ライフサイエンスコーパス: calcium concentration

1 by the substantial elevation of cytoplasmic calcium concentration.

2 displaying an acute effect on free cytosolic calcium concentration.

3 tive contribution dependent on extracellular calcium concentration.

4 pond to the signal of an increased cytosolic calcium concentration.

5 e of generating oscillatory power at a fixed calcium concentration.

6 wn (KD) cells were more sensitive to reduced calcium concentration.

7 ling and prevention of a deleterious rise in calcium concentration.

8 ts function and structure depend strongly on calcium concentration.

9 s to RyR1 at the apo site, regardless of the calcium concentration.

10 65% increase in the mean free intracellular calcium concentration.

11 y of NCAD12 dimers was strongly dependent on calcium concentration.

12 rently affected by increases in the external calcium concentration.

13 ting is regulated by changes in intraciliary calcium concentration.

14 iculin is remarkably thermostable at a given calcium concentration.

15 egulated in part by an optimal intracellular calcium concentration.

16 calcium channels rather than changes in bulk calcium concentration.

17 works responsive to changes in intracellular calcium concentration.

18 cells, and Akt, and increased intracellular calcium concentration.

19 velength modulations in response to changing calcium concentration.

20 of CaM (CaM1-80) binds weakly, regardless of calcium concentration.

21 the PAR1-mediated increase in intraplatelet calcium concentration.

22 pholipase C beta2 and increase intracellular calcium concentration.

23 response magnitude depends on extracellular calcium concentration.

24 with their ability to increase intracellular calcium concentration.

25 stinal epithelial migration and increases in calcium concentration.

26 n more sensitive to changes in environmental calcium concentration.

27 ntent, and increased the basal intracellular calcium concentration.

28 ion of membrane potential into intracellular calcium concentration.

29 ould be clearly distinguished by varying the calcium concentration.

30 anoconfined solution can be tuned by varying calcium concentration.

31 differentiation by an elevated extracellular calcium concentration.

32 bited persistent elevations in intracellular calcium concentration.

33 ponsible for oscillations in the cytoplasmic calcium concentration.

34 perties and its role in maintaining systemic calcium concentrations.

35 ents, or NMDA-induced increases in cytosolic calcium concentrations.

36 itochondria contact points and mitochondrial calcium concentrations.

37 was collected for a wide range of specified calcium concentrations.

38 um permeability and elevated basal cytosolic calcium concentrations.

39 dividual domains differ significantly at low calcium concentrations.

40 can also target Ser-282 at nonphysiological calcium concentrations.

41 ual actin filaments by VLN3 at physiological calcium concentrations.

42 accounted for 0.54% of the variance in serum calcium concentrations.

43 um and phosphorus concentrations or in urine calcium concentrations.

44 mal Ca(2+) buffering characteristics at high calcium concentrations.

45 sotopic ratio suggesting changes in seawater calcium concentrations.

46 e in substrate-adsorbed protein at different calcium concentrations.

47 Ser359 inhibits eEF2K activity even at high calcium concentrations.

48 tments also significantly reduced the plasma calcium concentrations.

49 measured over a range of extra mitochondrial calcium concentrations.

50 ogenesis in response to increasing cytosolic calcium concentrations.

51 ns under both physiological and pathological calcium concentrations.

52 el activity because of the low extracellular calcium concentrations (0.2-0.5 mM) used typically to as

53 .22, 0.96-1.55; p=0.1010) or raised adjusted calcium concentration (1.08, 0.88-1.34; p=0.4602).

54 2.05-2.60; p<0.0001), and raised total serum calcium concentration (1.43, 1.21-1.69; p<0.0001), but n

55 mulation frequencies (0.1-4 Hz) and external calcium concentrations (1.8-3.6 mm) at 37 degrees C.

56 At high nonphysiological calcium concentration, A8V, E134D, and D145E mutations m

57 VO) and non-DLVO forces as a function of the calcium concentration, also after charge reversal of bot

58 Pf) in response to increases in the external calcium concentration, an effect that is mediated by an

59 diameter caused rapid rises in intracellular calcium concentration, an effect that was inhibited by t

60 larly, SP-induced increases in intracellular calcium concentration and actomyosin stress fiber format

61 te (WPI) nanoparticles prepared by different calcium concentration and aggregation pH.

62 aneous correlated increases in intracellular calcium concentration and compound postsynaptic currents

63 hannel activity depends on the intracellular calcium concentration and is associated with D-serine re

64 uence channel sensitivity to fluctuations in calcium concentration and perhaps even metabolic state.

65 ations of glucose increase the intracellular calcium concentration and the frequency of alpha-cell ca

66 contact elimination depends on extracellular calcium concentration and the level of E-cadherin, sugge

67 lume of the synaptic terminal influences the calcium concentration and the number of available vesicl

68 ciliary calcium channel controlling ciliary calcium concentration and thereby modifying SMO-activate

69 fic synaptic changes through the dynamics of calcium concentration and thresholds implementing in sim

70 aPrm1 mutants was sensitive to extracellular calcium concentration and was associated with an increas

71 Gs that may serve to raise local cytoplasmic calcium concentrations and aid in refilling intracellula

72 a, Bmi-1, K15, and ABCG2), whereas increased calcium concentrations and air-lifting induced terminal

73 athyroid surgery include monitoring of serum calcium concentrations and bone density.

74 to occur fast robustly over a large range of calcium concentrations and hence energetic stabilities.

75 cal stimulation with increased intracellular calcium concentrations and increased inward cation curre

76 is maintained in the inactive state at basal calcium concentrations and is activated via CaM binding

77 strate that VWF binds calcium at physiologic calcium concentrations and that calcium stabilizes VWF A

78 topHluorin signals correlate with high local calcium concentrations and that local, spontaneous calci

79 M-free state, were able to bind CaM at lower calcium concentration, and had lower rates of heme reduc

80 ng plasticity at physiological extracellular calcium concentration, and highlight the role of synapti

81 sigmoidal dependence of key parameters with calcium concentration, and is simpler and more suitable

82 in which IQCG stores CaM at low cytoplasmic calcium concentrations, and releases CaM to activate CaM

83 d found that, at physiological endolymphatic calcium concentrations, approximately half of the mechan

84 As such, cellular and systemic calcium concentrations are tightly regulated.

85 brane potential and an increase in cytosolic calcium concentrations, are inhibited by low luminal pH

86 ike trains and/or time varying intracellular calcium concentrations--are hidden.

87 ees C evoked a 40% increase in intracellular calcium concentration as determined by live-cell confoca

88 ane to 180 mM makes it possible to determine calcium concentrations as high as 3 mM by chronopotentio

89 of TCRzeta, ZAP70, and LAT and intracellular calcium concentration, as well as IL-2 gene expression.

90 safety measures of renal function and serum calcium concentration assessed every 3 months.

91 uction is often an increase in intracellular calcium concentration associated with intracellular calc

92 obust molecular switch that is responsive to calcium concentrations associated with both the basal st

93 nses calcium over the physiological range of calcium concentrations associated with RyR1 regulation o

94 by CO2-rich brine with discrete increases in calcium concentration at reaction boundaries.

95 The increases in calcium concentration at the AIS evoked by subthreshold

96 llations; and 4), a threshold exists for the calcium concentration below which oscillations cease.

97 brane, a transient increase of intracellular calcium concentration, binding of calcium to troponin in

98 d to those of nicotine on intracellular free calcium concentration but were causally associated with

99 rthermore, the extension rate increases with calcium concentration, but at a given concentration, we

100 at keratinocytes proliferate in media of low calcium concentration, but rapidly commit to differentia

101 ease increased with an increase in the added calcium concentration, but the increase was dependent on

102 inhibits contractility at high intracellular calcium concentration by disrupting the actin-myosin ATP

103 rgoes dynamic polymerization with increasing calcium concentration by front-to-front dimerization and

104 xpressed by parathyroid cells controls blood calcium concentration by regulating parathyroid hormone

105 at membrane voltage (V(m)) and intracellular calcium concentrations (Ca) become dissociated during ve

106 e heart to function as a pump, intracellular calcium concentration ([Ca(2+) ]i ) must increase during

107 at cardiomyocytes and the free mitochondrial calcium concentration ([Ca(2+) ]m ) was measured at diff

108 Resting motile cilia calcium concentration ([Ca(2+)] ~170 nM) is only slightl

109 sis that Bid regulates endoplasmic reticulum calcium concentration ([Ca(2+)](ER)) homeostasis to affe

110 relationship between increased intracellular calcium concentration ([Ca(2+)](i)) and changes in spont

111 ial smooth muscle cell (PASMC) intracellular calcium concentration ([Ca(2+)](i)) and pH.

112 The intracellular calcium concentration ([Ca(2+)](i)) has been monitored u

113 e role of a Ca(2+) channel and intracellular calcium concentration ([Ca(2+)](i)) in osmotic stress-in

114 ay excitability in the form of intracellular calcium concentration ([Ca(2+)](i)) increases, but the s

115 causes a prolonged increase in intracellular calcium concentration ([Ca(2+)](i)) that inhibits EC mov

116 iol signaling increases the free cytoplasmic calcium concentration ([Ca(2+)](i)) that stimulates the

117 a significant increase in the intracellular calcium concentration ([Ca(2+)](i)) through activation o

118 al methods and measurements of intracellular calcium concentration ([Ca(2+)](i)) to show that TRPA1 i

119 Intracellular calcium concentration ([Ca(2+)](i)) was examined in rods

120 Intracellular calcium concentration ([Ca(2+)](i)) was measured by micr

121 Cytoplasmic calcium concentration ([Ca(2+)](i)) was measured in cult

122 ent early increase (30 min) in intracellular calcium concentration ([Ca(2+)](i)), following Abeta(1-4

123 The consequent lowering of the cytosolic calcium concentration ([Ca(2+)](i)), if protracted, can

124 arly and transient increase of intracellular calcium concentration ([Ca(2+)](i)), required for AhR-re

125 ed with stereotypic changes in intracellular calcium concentration ([Ca(2+)](i)), yet the target of t

126 As the free ionized plasma calcium concentration ([Ca(2+)](o)) of the fetus is high

127 Extracellular calcium concentration ([Ca(2+)](o)) regulates Ca(2+) ent

128 shows a limited dependence on extracellular calcium concentration ([Ca(2+)](o)), suggesting the invo

129 FSS rapidly increases the intracellular calcium concentration ([Ca(2+)]) and nitric oxide (NO) s

130 the power required for flight by varying the calcium concentration ([Ca(2+)]).

131 Transient elevations in intracellular calcium concentration ([Ca(2+)]i) and migratory pauses o

132 lpha7 nAChR agonist, increases intracellular calcium concentration ([Ca(2+)]i) mainly released from i

133 s of transmembrane voltage and intracellular calcium concentration ([Ca(2+)]i) that gate the channels

134 e arteries, coupling a rise of intracellular calcium concentration ([Ca(2+)]i) to endothelial cell hy

135 ed by a sustained elevation of intracellular calcium concentration ([Ca(2+)]i) which could not be blo

136 stimuli trigger increases in cytosolic free calcium concentration ([Ca(2+)]i).

137 ted by increases in astrocytic intracellular calcium concentrations ([Ca(2)(+)](i)).

138 ted by membrane voltage (Vm ), intracellular calcium concentrations ([Ca(2+) ]i ) and external permea

139 estradiol rapidly increased free cytoplasmic calcium concentrations ([Ca(2+)](i)) that facilitate pro

140 led simultaneous monitoring of intracellular calcium concentrations ([Ca(2+)]i) in multiple cells and

141 Ionized calcium concentration [Ca(2+)] was significantly lower i

142 ar to be in response to changes in cytosolic calcium concentration, [Ca(2+)](i).

143 activity in the regulation of intracellular calcium concentration ([Ca2+](i)) and secretion.

144 probability, Ca2+ sparks, and the myoplasmic calcium concentration ([Ca2+]i) during excitation-contra

145 Resting cytoplasmic calcium concentration ([Ca2+]i) in cultured preCGG hippo

146 in the membrane potential and intracellular calcium concentration ([Ca2+]i) in SCN neurons after sti

147 d agonist-induced increases in intracellular calcium concentration ([Ca2+]i), in both ECs and VSMCs.

148 Non-negativity constraints on the calcium concentration can also be incorporated using a l

149 fects of the imaging procedure, we show that calcium concentration can be estimated up to an affine t

150 fusion induced an increase in intracellular calcium concentration, causing premature oocyte activati

151 ary to expectation, does not affect the peak calcium concentration close to the source but sharpens t

152 d ROS levels and reduced basal intracellular calcium concentration compared with mock cells.

153 n of variation in CASR that influences serum calcium concentration confirms the results of earlier ca

154 indings, we suggest that decreased NADPH and calcium concentration contribute to subsequent respirato

155 Strikingly, calcium concentration controls the frequency, but not th

156 ion was dependent on a rise in intracellular calcium concentration derived from extracellular sources

157 alcium store, the evolution of intracellular calcium concentration during a train of long-lasting dep

158 The kinetics of solubility and ionic calcium concentration during in vitro digestion were stu

159 e role of GluN2 subunit differences on spine calcium concentration during several STDP protocols in a

160 odel the effects become apparent at elevated calcium concentrations, e.g., at [Ca(2+)] = 25 muM, taua

161 at: calcium signals in the form of cytosolic calcium concentration elevations are nonlinearly amplifi

162 mental in generating sustained intracellular calcium concentration elevations that are necessary for

163 ent cation environment, with the ER range of calcium concentrations enhancing stability, and calcium-

164 At the same calcium concentration, excimer emission increased also,

165 trocytes undergo elevations in intracellular calcium concentration following activation of G protein-

166 We detected a decrease in mitochondrial calcium concentration following exposure to Tat.

167 h mu-calpain (calpain1) requiring micromolar calcium concentrations for activation and m-calpain (cal

168 to measure a marked heterogeneity in average calcium concentrations from cell to cell in the basal ke

169 d active vitamin D while maintaining a serum calcium concentration greater than or the same as baseli

170 on, but rapidly commit to differentiation at calcium concentrations >0.07 mM after the initial attach

171 utoprocessing and activity were dependent on calcium concentrations >1 mm, consistent with the protei

172 f those protocols, increases in postsynaptic calcium concentration have been shown to play a crucial

173 egions could be modulated by controlling the calcium concentration: (i) at a low calcium concentratio

174 ere the dissolution of calcite increases the calcium concentration in a thin boundary layer in contac

175 ich leads to a greater rise in intracellular calcium concentration in aging than that in young neuron

176 CaSR inhibition increased blood calcium concentration in animals pretreated with a bisph

177 Here, using optical recordings of calcium concentration in ASE neurons in intact animals,

178 Additionally, the patient showed an elevated calcium concentration in blood and urine as well as neph

179 rization-activated current and intracellular calcium concentration in both normal control (NC) rats a

180 an increase in baseline and spike-triggered calcium concentration in both the AIS and nearby synapti

181 inetics of the changes in free mitochondrial calcium concentration in cardiac myocytes are largely un

182 inetics of the changes in free mitochondrial calcium concentration in cardiomyocytes.

183 uces a dose-dependent elevation in cytosolic calcium concentration in ET(B)-transfected cells and end

184 lours, and it is related to the increases in calcium concentration in germ and the formation of amylo

185 hermore, by measuring changes of cytoplasmic calcium concentration in hASCs during EFS, our findings

186 how that a chronic increase of the cytosolic calcium concentration in hepatocytes during obesity and

187 ffinity of the exhaustive nanosensors, total calcium concentration in human blood plasma was successf

188 The calcium concentration in mineral water was successfully

189 ICP-OES confirmed a substantial elevation of calcium concentration in mutant lenses.

190 ve been observed as spikes of the whole-cell calcium concentration in numerous cell types and are ess

191 osinophils showed an increased intracellular calcium concentration in response to Alternaria that was

192 the observations that STIM-1, the sensor of calcium concentration in stores, and Orai-1, the calcium

193 primary hippocampal neurons does not affect calcium concentration in the endoplasmic reticulum.

194 scale can be extended: (i) the extracellular calcium concentration in the experiments used to fit the

195 Importantly, with an increase of the calcium concentration in the growth medium, these phmSG

196 ry to the stratum corneum alterations in the calcium concentration in the outer epidermis are the pri

197 stress but are independent of intracellular calcium concentration in the physiological range.

198 e Nox5 activity was also observed with fixed calcium concentrations in an isolated enzyme activity as

199 These features enable NMR measurements of calcium concentrations in human serum in the presence of

200 Fluorescence imaging of intracellular calcium concentrations in live RA FLS stimulated with sp

201 MDA, or kainate (KA) increased intracellular calcium concentrations in RA FLS, demonstrating function

202 Calcium concentrations in the dispersed phase increased

203 We describe that the high calcium concentrations in the normal human host were tox

204 ical mapping of transmembrane potentials and calcium concentrations in the zebrafish heart.

205 Calcium concentrations increase considerably in gypsum-a

206 y for a calcium sensor, we found that higher calcium concentrations increased the lifetimes of the mi

207 d renal tubular calcium absorption and blood calcium concentration independent of PTH secretion chang

208 e that CaSR is a direct determinant of blood calcium concentration, independent of PTH, and modulates

209 lting transient increase in cytoplasmic free calcium concentration is a critical trigger for the init

210 Robust elevation of the cytosolic calcium concentration is a crucial early step for T cell

211 We show that peak calcium concentration is highly correlated with soma-syn

212 study was to test the hypothesis that serum calcium concentration is positively and independently as

213 The evolution of calcium concentration is represented through a smaller s

214 Uncorrected serum calcium concentration is the first mineral metabolism me

215 oidism has been described in which the serum calcium concentration is within normal range but parathy

216 um, villin can bundle F-actin and, at higher calcium concentrations, is capable of a gelsolin-like F-

217 ed by a transient rise in intracellular free calcium concentration linked to a change in the structur

218 At pCa levels above approximately 6.0 (i.e., calcium concentrations <1 microM), CK-2066260 increased

219 Here, we demonstrate that low calcium concentrations (<1.5 mg/L) that are found in man

220 chlear hair cell stereocilium where local mm calcium concentrations may exist.

221 directly visualized the close apposition of calcium concentration microdomains and synaptic release

222 naptic plasma membrane, have been defined as calcium concentration microdomains.

223 nsient, localized increases in intracellular calcium concentration near the calcium-conducting pores

224 The discovery that transient elevations of calcium concentration occur in astrocytes, and release '

225 e cytoplasm, we show that changes in ciliary calcium concentration occur without substantially alteri

226 At an external calcium concentration of 1 mM, and a membrane potential

227 and a temporal matrix that characterizes the calcium concentration of each neuron over time.

228 Furthermore, the intracellular calcium concentration of isolated neuroepithelial cells

229 Necrosis was induced using calcium concentrations of 100-500 mmol/L and injection v

230 e set out to assess effects of extracellular calcium concentration on isoflurane-induced caspase-3 ac

231 s in stimulation frequency and extracellular calcium concentration on the simulated Ca(2+) transient

232 re highly cooperative with respect to either calcium concentration or extent of cRLC phosphorylation.

233 d to E(2)(#) is lower at lower pH, at higher calcium concentrations, or with an inhibitor bound to th

234 At low luminal calcium concentrations, ouf8 had little detectable effec

235 ulin remained stably attached independent of calcium concentration (pCa 3-7).

236 nsensitive to both salt (25-1000 mm KCl) and calcium concentrations (pCa 3-7).

237 at individual sites is low at physiological calcium concentration, PF-PC synapses release one or mor

238 imental studies suggest that intrapancreatic calcium concentrations play an important role in the ini

239 asynchronous release increases with external calcium concentration, possibly suggesting that the mode

240 nd that the dominant folding pathway at high calcium concentrations proceeds via a transition state c

241 Increasing calcium concentrations progressively shift this equilibr

242 ve model, we show how membrane potential and calcium concentration provide a fast feedback that can e

243 Upon intense illumination, rhabdomeric calcium concentration reaches millimolar levels that wou

244 pic and metabotropic) that alter cytoplasmic calcium concentration (receptor-agonist challenges) and

245 allow us to propose a mechanistic model for calcium concentration regulated outer shell assembly.

246 cal positive-gating modulator and shifts the calcium-concentration response curve of KCa3.1 to the le

247 hich both lead to an elevated intraendosomal calcium concentration, resulted in the accumulation of i

248 The increase in baseline calcium concentration rose with depolarization and fell

249 el can fit all three data sets with the same calcium-concentration-sensitive parameters.

250 of a high prevalence of hyperparathyroidism, calcium concentrations should be checked before and duri

251 Culturing keratinocytes with increased calcium concentrations significantly induced S100/A11 ex

252 diffraction but only for its dormant or high-calcium-concentration state, not its low-calcium-concent

253 igh-calcium-concentration state, not its low-calcium-concentration state, which is relevant to viral

254 of CaxP was bacteriostatic in physiological calcium concentrations, suggesting a new antibiotic targ

255 dc73(L/L)/PTH-Cre mice had higher mean serum calcium concentrations than wild-type littermates, and C

256 lls caused rapid elevations in intracellular calcium concentration that were independent of phospholi

257 ling the calcium concentration: (i) at a low calcium concentration the droplets were evenly distribut

258 We propose a model whereby at low calcium concentrations the lectin-like module drops away

259 m influx is changed by altering the external calcium concentration, the calcium cooperativity of p is

260 Finally, above a threshold cadherin and calcium concentration, the cis and trans protein interac

261 we show that with increased bulk cytoplasmic calcium concentration, the CRU model exhibits determinis

262 In contrast, at lower physiological calcium concentration, the D145E mutation led to an appr

263 ation and illustration refer to a monitor of calcium concentration, the method is applicable to any s

264 evenly distributed; (ii) at an intermediate calcium concentration they formed a layer around the sta

265 around the starch granules; (iii) at a high calcium concentration they formed a network of aggregate

266 are impermeant and unable to bind PS at low calcium concentration, they are unsuitable for intracell

267 Glucagon increased cytosolic calcium concentration through the PKA-mediated phosphory

268 ular switch that ties shifting intracellular calcium concentration to association and dissociation of

269 Lowering extracellular calcium concentration to in vivo levels leads to an incr

270 s, and ultimately elevates the intracellular calcium concentration to increase the release of glutama

271 ffectors into macrophages and required lower calcium concentrations to activate type III secretion th

272 tant was identified which contains identical calcium concentrations to wild-type, but contains no oxa

273 r data suggest that changes in intracellular calcium concentrations triggered by nAChR activation can

274 in the transgenic mouse retinas at the free calcium concentrations typical for dark-adapted rods.

275 the lysoPC-induced increase in intracellular calcium concentration was inhibited in ECs transiently t

276 Calcium concentration was the only variable that influen

277 GWAS of serum calcium concentrations was performed in 20 611 individua

278 Changes of intracellular calcium concentration were involved not only in high glu

279 phorylation of Cx36 or in intracellular free calcium concentration were not involved in the observed

280 atively slow decreases in free mitochondrial calcium concentration were observed in rat cardiac myocy

281 caffeine, similar increases in intracellular calcium concentration were observed in Stac3-deleted and

282 Serum and urinary calcium concentrations were also measured.

283 Cytosolic calcium concentrations were assessed under the same expe

284 re media in which essential trace metals and calcium concentrations were manipulated.

285 Adverse events and plasma calcium concentrations were similar between groups.

286 g on CB(1) receptors increases intracellular calcium concentration when administered intracellularly

287 dimer disassembles rapidly regardless of the calcium concentration, whereas the disassembly of NCAD12

288 ensing receptors to changes in extracellular calcium concentrations, whereas autosomal dominant hypoc

289 ny synapses by increasing the intra-terminal calcium concentration, which may increase the quantal co

290 control is exerted by affecting the internal calcium concentration, which sets the resting open proba

291 The extracellular calcium concentration, which triggers activation of the

292 hyperexcited states cause high intracellular calcium concentrations, which could trigger transcriptio

293 II model system is never bistable at resting calcium concentrations, which suggests that CaMKII activ

294 with latrunculin A or reducing intracellular calcium concentration with BAPTA-AM.

295 ssessed the association of uncorrected serum calcium concentration with clinical outcomes.

296 Significantly, the binding mode depends on calcium concentration with important implications for ca

297 asymmetry caused a rise in the mitochondrial calcium concentration with stimulation frequency.

298 and cultured in low to medium (0.03-0.4 mM) calcium concentrations with proper serum levels (10% FCS

299 Local control of calcium concentration within neurons is critical for sig

300 However, moderate variations in calcium concentrations within the physiological range ca