ライフサイエンスコーパス: calcium pump

1 monomers, the active/inhibitory units of the calcium pump.

2 smic reticulum (ER) Ca2+-ATPase (SERCA)-type calcium pump.

3 cilitating recognition and inhibition of the calcium pump.

4 ing a sarco/endoplasmic reticulum (ER)-Golgi calcium pump.

5 form of a human erythrocyte plasma membrane calcium pump.

6 and inhibition of the sarcoplasmic reticulum calcium-pump.

7 s able to rescue a yeast mutant deficient in calcium pumps.

8 regional and cellular distribution of these calcium pumps.

9 spine neck, and (iii) the strength of spine calcium pumps.

10 , which harbors a deletion of its endogenous calcium pumps.

11 iffusion through the spine neck and by spine calcium pumps.

12 at a specific site of human plasma membrane calcium pump-2 transcripts.

13 , these results support a model in which the calcium pump activity of ACA12 is primarily regulated by

14 ffness may increase light-scattering, reduce calcium pump activity, alter protein-lipid interactions,

15 fold reduction in endoplasmic reticulum-type calcium pump activity.

16 ty and marked inhibition of the sarcoplasmic calcium pump affinity for calcium, resulting in depresse

17 a previously unknown lipid modulator of the calcium pump, an effect that may predispose kidney tissu

18 t to be found in a mammalian plasma membrane calcium pump and define a new class of deafness genes th

19 ding of Mg(2+) before P(i) implies that both calcium pump and sodium pump form a ternary enzyme.metal

20 calmodulin (CaM) can affect the activity of calcium pumps and channels to modulate the amplitude and

21 ical model, we find that the contribution of calcium pumps and diffusion varies from spine to spine.

22 and U-73122 are inhibitors of plant type IIA calcium pumps and phospholipase C, respectively, and imp

23 We conclude that dendritic spines have calcium pumps and that their density and kinetics, toget

24 dies have aimed to explain how it influences calcium pumps and to determine whether it acts as an ion

25 uxes via the calcium current (I(Ca)), the SR calcium pump, and passive leak from the SR were evaluate

26 r phosphorylation and dephosphorylation, the calcium pump appears to catalyze phosphoryl group transf

27 ylation in the 3' untranslated region of the calcium pump ATP2A3 gene.

28 codes the sarcoplasmic/endoplasmic reticulum calcium-pumping ATPase SERCA2, which has a central role

29 A selective electrochemical calcium pump based on a fast diffusive calcium ionophore

30 n, an inhibitor of the endoplasmic reticulum calcium pumps, but buffering cytosolic calcium had no ef

31 integral membrane protein that regulates the calcium pump (Ca-ATPase) in cardiac sarcoplasmic reticul

32 ependent protein kinase, which activates the calcium pump (Ca2+-ATPase).

33 Calcium pump-catalyzed (18)O exchange between inorganic

34 mbrane domains, raising the possibility that calcium pumps contribute to local Ca(2+) signaling.

35 TP-sensitive K(+) current, a plasma membrane calcium-pump current and a Na(+) background current.

36 ing immunogold cytochemistry and showed this calcium pumping enzyme to be present throughout the subs

37 We found that the net SR calcium pump flux and rate of [Ca](i) decline decreased

38 pproximately 6-fold), and the probability of calcium pump forming phosphoenzyme from bound P(i) (P(c)

39 The calcium pump from sarcoplasmic reticulum (Ca2+-ATPase) i

40 Expression of the calcium pump had little effect on the induction of prest

41 Having demonstrated the efficiency of the calcium pump in background electrolyte solutions, a comp

42 LB), a 52-residue protein that regulates the calcium pump in cardiac muscle.

43 ects of the fractions on the plasma membrane calcium pump in human red blood cells were assessed.

44 oplasmic-endoplasmic reticulum Ca(2+)-ATPase calcium pump in mammals and is of industrial importance

45 Cyclopiazonic acid (an inhibitor of the calcium pump in the S-ER membrane) and caffeine or ryano

46 tructural demonstration of abundant sites of calcium pumps in the SSC supports a role for this struct

47 amino acid protein, regulates the Ca-ATPase (calcium pump) in cardiac sarcoplasmic reticulum (SR) thr

48 l membrane protein, regulates the Ca-ATPase (calcium pump) in cardiac sarcoplasmic reticulum through

49 lear differences between some members of the calcium pumps indicate that evolutionarily conserved clu

50 d (10-30 microM CPA), an inhibitor of the ER calcium pump, inhibited the calcium rise produced by TMA

51 ffects by sarcoplasmic/endoplasmic reticulum calcium pump inhibition are proposed to occur.

52 by store-depletion with Ca(2+) chelators or calcium pump inhibitors.

53 Thus, ER calcium-pump inhibitors represent a potential target for

54 Treatment with aerosolized calcium-pump inhibitors reversed the nasal epithelial po

55 "Backflux" through the SR calcium pump is a critical feature which allows realisti

56 onclude that the reverse flux through the SR calcium pump is an important factor in comprehensive und

57 t hippocampus, we identified plasma membrane calcium pump isoform 1 (PMCA1), a plasma membrane calciu

58 Alternate splicing of human plasma membrane calcium pump isoform 4 (hPMCA4) transcripts causes the e

59 a and b variants of the rat plasma membrane calcium pump, isoform 2 (rPMCA2a and rPMCA2b), were cons

60 lasmic reticulum calcium ATPase] and SERCA2a calcium pump isoforms by phospholamban (PLB), we quantif

61 intact myocytes both forward and reverse SR calcium pump kinetics as well as intra-SR calcium buffer

62 Regulation of the calcium pump of the cardiac sarcoplasmic reticulum by ph

63 o(endo)plasmic reticulum calcium ATPase, the calcium pump of the endoplasmic reticulum.

64 increasing evidence placing the sarcolemmal calcium pump, or plasma membrane calcium/calmodulin ATPa

65 The plasma membrane calcium pump (PMCA) is the only active Ca2+ transporter

66 Overexpression of the plasma membrane calcium pump (PMCA) isoform 4b by means of the baculovir

67 sion at the protein level of plasma membrane calcium pump (PMCA) isoforms in rat brain was detected b

68 calmodulin (CaM) vary among plasma membrane calcium pump (PMCA) isoforms.

69 f this work was to study the plasma membrane calcium pump (PMCA) reaction cycle by characterizing con

70 ulatory factor 1 (NHERF1) interacts with the calcium pump PMCA2 and the tyrosine kinase receptor ErbB

71 unctional variant (V586M) in plasma-membrane calcium pump PMCA2, which is encoded by ATP2B2, was asso

72 colleagues demonstrate that inhibiting SERCA calcium pumps preferentially impairs the maturation of t

73 ul effects of perturbations in plasma and ER calcium pump rates and the current through the CRAC chan

74 MDA receptor, and endoplasmic reticulum (ER) calcium pump, sacro-/ER calcium ATPase (SERCA1).

75 on, sitagliptin preserves function of the ER calcium pump, sarco-endoplasmic reticulum Ca(2+)-ATPase

76 The calcium pump sarcoplasmic reticulum Ca(2+)-ATPase (SERCA

77 d molecular dynamics (MD) simulations of the calcium pump (sarcoplasmic reticulum Ca(2+)-ATPase (SERC

78 -poor ER membrane inhibits the macrophage ER calcium pump, sarcoplasmic-endoplasmic reticulum calcium

79 nterest such as adenylate kinase, ATP-driven calcium pump SERCA, leucine transporter and glutamate tr

80 The sarcoplasmic reticulum calcium pump (SERCA) and its regulator, phospholamban, a

81 ial cells modulates ER store by upregulating calcium pump (SERCA) expression without affecting the re

82 The sarcoplasmic reticulum calcium pump (SERCA) is regulated by the small integral

83 duced activity of the sarcoplasmic reticulum calcium pump (SERCA), contribute to this contractile dys

84 h Hif-1alpha-dependent overexpression of the calcium pump SERCA2 (sarcoplasmic/endoplasmic reticulum

85 nvestigated whether overexpression of the SR calcium pump (SERCA2a) in transgenic mice could reduce t

86 show that the thioredoxin TMX1 inhibits the calcium pump SERCA2b at ER-mitochondria contact sites, t

87 en in human haploid cells and identified the calcium pump SPCA1.

88 function, our data suggest that PMCA1a is a calcium pump specialized for neurons, where it may contr

89 very strong inhibitor of the red blood cell calcium pump, suggesting that this substance may have re

90 ntained a powerful specific inhibitor of the calcium pump that had little or no effect on the Na+/K+-

91 eplete albumin, secreted an inhibitor of the calcium pump that migrated in the same chromatographic b

92 lasma membrane calcium ATPase 2 (PMCA2) is a calcium pump that plays important roles in neuronal func

93 bitor of an adenosine-5'-triphosphate-driven calcium pump, the Ca2+-ATPase.

94 s correlates with the higher expression of a calcium pump, the gene for which was cloned and sequence

95 interacts with the cytoplasmic domain of the calcium pump to relieve its inhibition.

96 latory protein phospholamban can inhibit the calcium pump, we evaluated it as a potential target to i

97 cally activated by Na(+) or K(+); and in the calcium pump, where a niche is integrally involved in th

98 his work is that the coupling of a selective calcium pump with a thin layer element can give rise to

99 h phorbol myristate acetate or poisoning the calcium pump with thapsigargin stimulates transcytosis o

100 Ca2+ release; however, after inhibiting the calcium pump with thapsigargin the same stimulus release

101 In contrast, poisoning intracellular calcium pumps with thapsigargin increases calcium mobili