ライフサイエンスコーパス: calcium-ATPase

1 activation of SERCA (sarcoplasmic reticulum calcium ATPase).

2 mban, and sarcoplasmic/endoplasmic reticulum calcium ATPase).

3 ban in regulating the sarcoplasmic reticulum calcium ATPase.

4 um pump isoform 1 (PMCA1), a plasma membrane calcium ATPase.

5 (+)-ATPase, but failed to have any effect on calcium ATPase.

6 ole as a regulator of sarcoplasmic reticulum calcium ATPase.

7 e) and stimulation of sarcoplasmic reticulum calcium ATPase.

8 itor of the endoplasmic reticulum-associated calcium-ATPase.

9 ilin and the Ca(2+) ATPase secretory pathway calcium ATPase 1 (SPCA1) in the sorting of soluble secre

10 it co-localizes with PMCA1b (plasma membrane calcium ATPase 1b).

11 nsitivity to pain stimuli in plasma membrane calcium ATPase 2 (PMCA2) heterozygous mice: a possible m

12 Plasma membrane calcium ATPase 2 (PMCA2) is a calcium pump that plays im

13 , whereas sarcoplasmic endoplasmic reticular calcium ATPase 2 abundance and sarcoplasmic reticulum Ca

14 gets both sarcoplasmic/endoplasmic reticulum calcium ATPase 2 and a novel Golgi inhibitor.

15 that is, sarcoplasmic/endoplasmic reticulum calcium ATPase 2 and the Na(+)/Ca(2+) exchanger.

16 ncreased SERCA2 (Sarco/Endoplasmic Reticulum Calcium ATPase 2) expression, which correlated with a le

17 p SERCA2 (sarcoplasmic/endoplasmic reticulum calcium ATPase 2).

18 e, as was sarcoplasmic endoplasmic reticular calcium ATPase 2/phospholamban protein ratio (45% reduce

19 MECs express the plasma membrane calcium-ATPase 2 (PMCA2), which transports calcium acros

20 he expression of sarco/endoplasmic reticulum calcium ATPase-2 (SERCA2), a protein that transports cal

21 izes with sarcoplasmic/endoplasmic reticulum calcium/ATPase-2 and calreticulin at membrane-bound cyto

22 ting the cardiac sarco/endoplasmic reticulum calcium ATPase 2a (SERCA2a) in the regulation of overall

23 creases in homogenate sarcoplasmic reticulum calcium ATPase-2a (SERCA2a) activity, protein density, a

24 fibrosis, normalized sarcoplasmic reticulum calcium ATPase-2a activity and expression of UCP-2 and U

25 nterstitial fibrosis, sarcoplasmic reticulum calcium ATPase-2a activity, expression of mitochondria u

26 eostasis through preserving sarcoplasmic/EnR calcium ATPase 2b (SERCA2b) function in AI-resistant cel

27 ium pump, sarcoplasmic-endoplasmic reticulum calcium ATPase-2b (SERCA2b).

28 oach, we discovered that the plasma membrane calcium ATPase 4 (PMCA4) is required for TNF-induced cel

29 aracrine mechanism involving plasma membrane calcium ATPase 4 (PMCA4).

30 explored the role played by plasma membrane calcium ATPase-4 (PMCA4) and its alternative splice vari

31 activity is elevated, and Na+-K+-ATPase and calcium ATPase activities are subnormal.

32 RS and the decrease of Na(+)-K(+)-ATPase and calcium ATPase activities in retinas of diabetic animals

33 The myosin high-salt EDTA and calcium ATPase activities of the isolated modified S1 we

34 -induced decreases of both Na+-K+-ATPase and calcium ATPase activities.

35 e calcium channel/sarcoendoplasmic reticulum calcium-ATPase activity and cardiac tissue fibrosis.

36 +) channels, N-methyl-d-aspartate receptors, calcium ATPase, adenomatous polyposis coli, and PTEN tum

37 ochondrial lipids and sarcoplasmic reticulum calcium ATPase after reperfusion.

38 SERCA2a (sarcoplasmic-endoplasmic reticulum calcium ATPase), along with an increased BNIP3 expressio

39 76, and PLCgamma2 as well as plasma membrane calcium ATPase and focal adhesion kinase.

40 e to mitochondria and sarcoplasmic reticulum calcium ATPase and restored mitochondrial and cardiac fu

41 inhibitors of the sarcoendoplasmic reticulum calcium ATPase and ryanodine receptor.

42 e to mitochondria and sarcoplasmic reticulum calcium ATPase and to impaired functional recovery.

43 tectable abundance of sarcoplasmic reticulum calcium-ATPase and sodium calcium exchanger were greater

44 ion of SERCA1a [sarco(endo)plasmic reticulum calcium ATPase] and SERCA2a calcium pump isoforms by pho

45 Interestingly, we identified calcium ATPases as ABCD2-binding partners, suggesting a

46 estrated by the preferential localization of calcium ATPases at one cell pole, in a ring pattern, fac

47 SERCA, a sarco-endoplasmic reticulum calcium ATPase, being the main agent for calcium uptake

48 nce ryanodine and sarcoendoplasmic reticulum calcium-ATPase blockers altered the time course and magn

49 and cardiac muscle, where it inhibits SERCA (calcium ATPase) by lowering its apparent Ca2+ affinity i

50 tained both a sodium/calcium exchanger and a calcium ATPase (Ca-ATPase).

51 pholamban-sarcoplasmic/endoplasmic reticulum calcium ATPase complex.

52 In vivo both of these calcium ATPases function to maintain millimolar levels o

53 ) vector carrying the sarcoplasmic reticulum calcium ATPase gene (AAV1/SERCA2a) in patients with adva

54 The sodium-calcium exchanger and sarcolemmal calcium ATPase had a lower activity and the exchanger wa

55 idue integral membrane protein that inhibits calcium ATPase in the cardiac sarcoplasmic reticulum.

56 etes-induced reductions in Na+-K+-ATPase and calcium ATPase in the retina are mediated in large part

57 oding beta1- and beta2-adrenergic receptors, calcium ATPase in the sarcoplasmic reticulum, and alpha-

58 e further insights into the critical role of calcium ATPases in maintaining epidermal integrity.

59 gargin, a sarcoplasmic/endoplasmic reticulum calcium ATPase inhibitor that induces ER stress, underwe

60 IP3), the sarcoplasmic-endoplasmic reticulum calcium ATPase inhibitor, thapsigargin, and the calcium

61 s were induced to undergo apoptosis with the calcium ATPase inhibitor, thapsigargin, or the glucocort

62 with the sarcoplasmic-endoplasmic reticulum calcium ATPase inhibitor, thapsigargin, was completely b

63 channel release activator (caffeine) and SR calcium-ATPase inhibitor (cyclopiazonic acid), consisten

64 th the kinase inhibitor staurosporine or the calcium-ATPase inhibitor thapsigargin.

65 a decrease in the levels of plasma membrane calcium ATPase isoform 2 (PMCA2), a major pump extruding

66 l as an activation of sarcoplasmic reticulum calcium ATPase isoform 2 and citrate synthase, was evide

67 ntified the calcium exporter plasma membrane calcium ATPase isoform 4 (PMCA4) as the interaction part

68 gin-resistant activity was a plasma membrane calcium ATPase isoform in transit to the plasma membrane

69 ump was a sarcoplasmic/endoplasmic reticulum calcium ATPase isoform.

70 Plasma membrane calcium ATPase isoforms (PMCAs) are expressed in a wide

71 Inhibition of sarco-endoplasmic reticulum calcium ATPase led to store depletion and dramatic redis

72 ession of sarcoplasmic/endoplasmic reticular calcium ATPase, less stored calcium, smaller calcium tra

73 ionophore, and thapsigargin, an inhibitor of calcium ATPase, mimicked the ET-1-stimulated PGHS-2 mRNA

74 se had an increase in sarcoplasmic-reticulum calcium ATPase mRNA and alpha-myosin heavy chain mRNA an

75 timulated decrease in sarcoplasmic reticulum calcium ATPase mRNA.

76 malarial exerts its activity by inhibiting a calcium ATPase (PfATP6) that is most similar to sarcopla

77 ntly described by our group, plasma membrane calcium ATPase (PMCA) activity can be regulated by the a

78 H+ uptake by the ubiquitous plasma membrane calcium ATPase (PMCA) has not been measured in any neuro

79 on is internalization of the plasma membrane calcium ATPase (PMCA).

80 Inhibition of plasma membrane calcium-ATPase (PMCA) attenuated these effects, as did d

81 The plasma membrane calcium-ATPase (PMCA) helps to control cytosolic calcium

82 lar calcium ([Ca2+](i)), the plasma-membrane calcium-ATPase (PMCA) may actively contribute to the gen

83 Plasma membrane calcium ATPases (PMCAs) actively extrude Ca(2+) from the

84 ) extrusion by high-affinity plasma membrane calcium ATPases (PMCAs) is a principal mechanism for the

85 Plasma membrane calcium ATPases (PMCAs), responsible for high-affinity C

86 ily of Ca(2+) pumps includes plasma membrane calcium ATPases (PMCAs).

87 oads due to the abundance of plasma membrane calcium ATPases (PMCAs).

88 The plasma membrane calcium ATPase pump (PMCA) is one of two major mechanism

89 2 trial targeting the sarcoplasmic reticulum calcium ATPase pump (SERCA2a), along with the start of m

90 Treatment of DM with a calcium ATPase pump inhibitor substantially recapitulate

91 bling the sarcoplasmic/endoplasmic reticulum calcium ATPase pump-leak system and suggest that it is i

92 te to the sarcoplasmic/endoplasmic reticulum calcium ATPase pump.

93 We have used thapsigargin (TG), an ER calcium-ATPase pump inhibitor that induces calcium relea

94 7-nAChRs are associated with plasma membrane calcium-ATPase pump isoform 2 (PMCA2).

95 hapsigargin, an inhibitor of the endoplasmic calcium-ATPase pump.

96 /l of the SERCA (sarco/endoplasmic reticulum calcium ATPase) pump inhibitor thapsigargin and reduced

97 ytoplasm, where it repletes the ER store via calcium-ATPases pumps.

98 tions of regulatory membrane proteins of the calcium ATPase SERCA, namely sarcolipin and phospholamba

99 gargin, a sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) (Ca2+ pump) blocker.

100 ion of CLNX with sarco endoplasmic reticulum calcium ATPase (SERCA) 2b results in inhibition of intra

101 sequence of sarco endoplasmic reticulum (ER) calcium ATPase (SERCA) 2b to inhibit Ca2+ oscillations.

102 he inhibition of sarco/endoplasmic reticulum calcium ATPase (SERCA) activity and ER stress.

103 used by impaired sarco/endoplasmic reticulum calcium ATPase (SERCA) activity due to altered phospholi

104 s modulation of sarco(endo)plasmic reticulum calcium ATPase (SERCA) activity.

105 The sarco(endo)plasmic reticulum calcium ATPase (SERCA) and its regulatory partner phosph

106 plasmic reticulum (ER) Ca(2+) pump sarco-/ER calcium ATPase (SERCA) and the single transmembrane-solu

107 structure, and sarco(endo)plasmic reticulum calcium ATPase (SERCA) binding were quantified by fluore

108 Sarco/endoplasmic reticulum calcium ATPase (SERCA) channels emerged at the intersect

109 The cardiac sarco/endoplasmic reticulum calcium ATPase (SERCA) establishes the intracellular cal

110 hat a decline in sarco/endoplasmic reticulum calcium ATPase (SERCA) function occurs with advancing ag

111 ose, a blocker of sarcoendoplasmic reticulum calcium ATPase (SERCA) had little effect on OCR despite

112 The sarco/endoplasmic reticulum calcium ATPase (SERCA) is essential for the control of i

113 The sarco(endo)plasmic reticulum calcium ATPase (SERCA) is regulated in a tissue-dependen

114 The sarcoplasmic reticulum calcium ATPase (SERCA) plays a central role in regulatin

115 The sarcoendoplasmic reticulum calcium ATPase (SERCA) plays a key role in cardiac calci

116 highly abundant sarco/endoplasmic reticulum calcium ATPase (SERCA) pump.

117 sP(3)R)], sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pumps, bradykinin receptors, and

118 Ca2+ channels and sarcoendoplasmic reticulum calcium ATPase (SERCA) pumps.

119 ibitor of sarcoplasmic endoplasmic reticulum calcium ATPase (SERCA)) while 1-EBIO (300 microM, an IKC

120 uding the sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA), calreticulin, and calsequestrin,

121 onists of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA), cyclopiazonic acid, and thapsiga

122 ylation activates the sarcoplasmic reticulum calcium ATPase (SERCA), which reduces cytoplasmic Ca(2+)

123 raction with the sarco-endoplasmic reticulum calcium ATPase (SERCA).

124 efilling via the sarco/endoplasmic reticulum calcium ATPase (SERCA).

125 tags to PLB and sarco/endoplasmic reticulum calcium ATPase (SERCA).

126 thapsigargin in sarco/endoplasmic reticulum calcium ATPase (SERCA).

127 r by transfecting sarcoendoplasmic reticulum calcium ATPase (SERCA).

128 Reduced expression of sarcoplasmic reticulum calcium ATPase (SERCA)2 and other genes in the adult car

129 hibitors of sarco- and endoplasmic reticulum calcium-ATPase (SERCA) have important therapeutic value

130 ed mild ER stress and inhibition of sarco/ER calcium-ATPase (SERCA) without significant increase in s

131 ng regulation of sarco/endoplasmic reticulum calcium-ATPase (SERCA).

132 The calcium ATPase SERCA1 was coexpressed with the potassium

133 skeletal muscle sarco(endo)plasmic reticulum calcium ATPase (SERCA1) gene is transactivated as early

134 asmic reticulum (ER) calcium pump, sacro-/ER calcium ATPase (SERCA1).

135 own-regulation of the sarcoplasmic reticulum calcium ATPase (SERCA2a) by GSK-3beta, acting at the lev

136 ession of the cardiac sarcoplasmic reticulum calcium ATPase (SERCA2a), a critical pump regulating cal

137 The sarcoplasmic reticulum calcium ATPase SERCA2b is an alternate isoform encoded b

138 3)Rs) and sarcoplasmic/endoplasmic reticulum calcium ATPases (SERCAs).

139 imilar to sarcoplasmic endoplasmic reticulum calcium ATPases (SERCAs).

140 or actin and P-type ATPase secretory pathway calcium ATPase (SPCA)-dependent sorting of secretory pro

141 ltiazem), ryanodine and inhibitors of the SR calcium ATPase (thapsigargin, cyclopiazonic acid) were w

142 f IRS-1 and the sarco(endo)plasmic reticulum calcium ATPase, the calcium pump of the endoplasmic reti

143 ine changes in expression of plasma membrane calcium ATPase type 2 (PMCA2), a high-affinity calcium e

144 hich encodes the sarco-endoplasmic reticulum calcium ATPase type 2 (SERCA2).

145 revealed that PDE3A associates with both SR calcium ATPase type 2a and phospholamban in a complex th

146 ns containing macromolecular complexes of SR calcium ATPase type 2a-phospholamban-PDE3A.

147 and upregulated sarco(endo)plasmic reticulum calcium-ATPase type 2 (SERCA2).

148 calcium channel, sarco/endoplasmic reticulum calcium-ATPase type 2a, Kv1.4, and Kv4.3 were downregula

149 Cav1 and the localization of plasma membrane calcium ATPase was disrupted.

150 The change in sarcoplasmic-reticulum calcium ATPase was not present in the patients in the pl

151 nto contact with the PLB binding site on the calcium ATPase, while the presence of twisting motions a

152 s similar to that for phosphorylation of the calcium ATPase with and without initial incubation with

153 nhibiting sarcoplasmic/endoplasmic reticulum calcium ATPase with cyclopiazonic acid or thapsigargin),