ライフサイエンスコーパス: calcium-activated potassium channel

1 g protein) modulates the Drosophila SLOWPOKE calcium-activated potassium channel.

2 um efflux from RBCs is the Gardos channel, a calcium-activated potassium channel.

3 e Drosophila slowpoke gene encodes a BK-type calcium-activated potassium channel.

4 ither large- (BK) or small- (SK) conductance calcium-activated potassium channels.

5 o mediate efferent inhibition via associated calcium-activated potassium channels.

6 current, and higher concentrations activated calcium-activated potassium channels.

7 ropic acetylcholine receptors and associated calcium-activated potassium channels.

8 enced by the activation of small-conductance calcium-activated potassium channels.

9 ue to an increase in the open probability of calcium-activated potassium channels.

10 ation of small- and intermediate-conductance calcium-activated potassium channels.

11 cellular calcium that gated surface-membrane calcium-activated potassium channels.

12 ncreases the expression of small-conductance calcium-activated potassium channels.

13 I(AHP) was occluded by previous blockade of calcium-activated potassium channels.

14 urkinje neurons via decreased recruitment of calcium-activated potassium channels.

15 paradoxically mimics the effects of blocking calcium-activated potassium channels.

16 nels is to provide calcium for activation of calcium-activated potassium channels.

17 ium influx couples to large conductance (BK) calcium-activated potassium channels.

18 inding and also normalized large-conductance calcium-activated potassium channel activity.

19 ized protein levels of the large conductance calcium-activated potassium channel and the water channe

20 e established by the interactions between BK calcium-activated potassium channels and an L-type calci

21 mechanisms underlying seizure generation (BK calcium-activated potassium channels and interneuron-exp

22 d after acute dissociation, we found that BK calcium-activated potassium channels and Kv2 channels bo

23 This work shows that BK calcium-activated potassium channels and Kv2 voltage-act

24 results in the opening of large-conductance, calcium-activated potassium channels, and an attendant h

25 Here we demonstrate that calcium-activated potassium channels are activated exclu

26 P/Q-type voltage-gated calcium channels and calcium-activated potassium channels are required for no

27 he cloning and characterization of two novel calcium-activated potassium channel beta subunits, hKCNM

28 nique splice variant of a large conductance, calcium-activated potassium channel (BK channel).

29 A high-conductance calcium-activated potassium channel (BK KCa) was charact

30 ET-cGMP-S (50 muM), and the high-conductance calcium-activated potassium channel (BK(Ca) channel) inh

31 the function of both the large conductance, calcium-activated potassium channel (BK) and specific me

32 Large-conductance calcium-activated potassium channels (BK channels) are a

33 he presence of functional large-conductance, calcium-activated potassium channels (BK channels) on th

34 Large conductance, calcium-activated potassium channels (BK(Ca) or maxi-K)

35 RATIONALE: Large-conductance calcium-activated potassium channels (BK) are composed o

36 Voltage- and calcium-activated potassium channels (BK) are important

37 Large-conductance calcium-activated potassium channels (BK) are potent neg

38 fects of ethanol (EtOH) on large-conductance calcium-activated potassium channels (BK) in cell bodies

39 Mammalian large-conductance, voltage- and calcium-activated potassium channels (BK, K(Ca)1.1) are

40 Large conductance calcium-activated potassium channels (BK, MaxiK, Slo) ha

41 as recombinant cell lines (large-conductance calcium-activated potassium channel, BK(Ca)).

42 rt through cGMP-mediated activation of large calcium-activated potassium channels (BKCa).

43 as limited by activation of putative BK-type calcium-activated potassium channels (blocked by 250 mic

44 reductions in the sensitivity to the BK-type calcium-activated potassium channel blocker iberiotoxin.

45 y the CYP inhibitor, SKF525A, but not by the calcium-activated potassium channel blocker, charybdotox

46 ely prolonged by small-conductance (SK-type) calcium-activated potassium channel blockers in normally

47 fication of a role for the large conductance calcium-activated potassium channel brings new thinking

48 Inhibiting calcium-activated potassium channels by charybdotoxin or

49 vessels to adenosine; however, inhibition of calcium-activated potassium channels by iberiotoxin had

50 owed that slowpoke mutations, which affect a calcium-activated potassium channel, cause severe song a

51 mino acid level with three small conductance calcium-activated potassium channels cloned from brain.

52 nergic neuron burst firing by decreasing the calcium-activated potassium channel current (SK), as wel

53 ntial (AP) repolarization; small-conductance calcium-activated potassium channel currents generate an

54 For large-conductance calcium-activated potassium channels, data are satisfact

55 The Drosophila large-conductance calcium-activated potassium channel (dSlo) binds to and

56 ates the fibroblast intermediate conductance calcium-activated potassium channel, FIK, a positive reg

57 hKCa4, encoding an intermediate conductance, calcium-activated potassium channel from a human lymph n

58 tional regulation of the Drosophila slowpoke calcium-activated potassium channel gene is complex.

59 a2, Myl3, and Myom1, myofibril proteins; and calcium-activated potassium-channel gene activity (KCNMB

60 howed several significant results, including calcium-activated potassium channels (GO:0016286; P=2.30

61 An intermediate conductance calcium-activated potassium channel, hIK1, was cloned fr

62 ctifier channels (I(KV)) and noninactivating calcium-activated potassium channels (I(BK,steady)), and

63 co-localization of intermediate-conductance calcium-activated potassium channels (IKCa) and IP3 rece

64 e colocalization of intermediate-conductance calcium-activated potassium channels (IKCa) and TRPV4 ch

65 ane blockers of the intermediate conductance calcium-activated potassium channel, IKCa1, have therape

66 f N-type voltage-gated calcium channels with calcium-activated potassium channels in DCN neurons.

67 f calcium-calmodulin-dependent kinase II and calcium-activated potassium channels in mediating these

68 The role of calcium-activated potassium channels in the regulation o

69 sistent with native intermediate conductance calcium-activated potassium channels, including the eryt

70 In addition, the activity of calcium-activated potassium channels increased markedly.

71 nel inhibitor), and iberiotoxin (100 nmol/L, calcium-activated potassium channel inhibitor).

72 rther demonstrate that the activation of the calcium-activated potassium channel is sufficient to ind

73 The opening of large-conductance calcium-activated potassium channels is a common endogen

74 voltage-gated potassium channels (K(v)) and calcium-activated potassium channels (K(Ca)).

75 muscle, we investigated the contribution of calcium-activated potassium channels (KCa) and endotheli

76 Large-conductance calcium-activated potassium channel (KCa1.1; BK, Slo1, M

77 The intermediate conductance calcium-activated potassium channel KCa3.1 contributes t

78 The calcium-activated potassium channel KCa3.1 controls diff

79 The calcium-activated potassium channel KCa3.1 is critically

80 The intermediate-conductance calcium-activated potassium channel KCa3.1 is expressed

81 Small conductance calcium-activated potassium channels link elevations of

82 Large-conductance calcium-activated potassium channels (maxi-K channels) h

83 Large conductance voltage- and calcium-activated potassium channels (MaxiK, BK(Ca)) are

84 ctivating A-current or the large conductance calcium-activated potassium channel-mediated fast spike

85 Because the large conductance calcium-activated potassium channel mSlo is sensitive to

86 The X-ray structure of the calcium-activated potassium channel MthK, which was crys

87 ne for hSK4, a novel human small conductance calcium-activated potassium channel, or SK channel, has

88 hese findings suggest that the maturation of calcium-activated potassium channels, particularly the a

89 members of the small-intermediate family of calcium-activated potassium channel proteins.

90 Cloned SK channels (small conductance calcium-activated potassium channel) recapitulate these

91 Calcium-activated potassium channels regulate AHP and ex

92 ated potassium channel and large-conductance calcium-activated potassium channel, respectively).

93 which selectively block the small and large calcium-activated potassium channels, respectively, resu

94 BK large conductance voltage- and calcium-activated potassium channels respond to elevatio

95 Small conductance calcium-activated potassium channels show a distinct pha

96 is associated with reduced small-conductance calcium-activated potassium channel (SK) currents and de

97 Small conductance calcium-activated potassium channels (SK channels) are p

98 rated by the activation of small-conductance calcium-activated potassium channels (SK channels).

99 The activation of small-conductance calcium-activated potassium channels (SK) has a profound

100 s were analyzed in native (small-conductance calcium-activated potassium channel, SK(Ca)) as well as

101 ing peptide (GRP) and the small conductance, calcium-activated potassium channel, SK2.

102 releasing peptide and the small conductance, calcium-activated potassium channel, SK2.

103 We found that the calcium-activated potassium channel SK3 and the G protei

104 Administration of an activator of calcium-activated potassium channels, SKA-31, partially

105 Apamin-sensitive small conductance calcium-activated potassium channels (SKCa1-3) mediate t

106 triarylmethane-insensitive small conductance calcium-activated potassium channel SKCa3 into IKCa1 ren

107 (HVA) (N- and P/Q-type) calcium channels and calcium-activated potassium channels (SKKCa).

108 eterminant of its anthelmintic effect is the calcium-activated potassium channel SLO-1.

109 to, but distinct from, the small conductance calcium-activated potassium channel subfamily, which is

110 egulating voltage-gated calcium channels and calcium-activated potassium channels that together contr

111 ium was similar to that of small conductance calcium-activated potassium channels, the slope factor d

112 he contribution of the SK (small-conductance calcium-activated potassium) channel to neuronal functio

113 botropic glutamate receptors or postsynaptic calcium-activated potassium channels, two conditions tha

114 Calcium-activated potassium channels were analyzed in na

115 tent with the SK class of small-conductance, calcium-activated potassium channels, which contribute t

116 d is abolished by blocking small conductance calcium-activated potassium channels with apamin.

117 ent is reduced by blocking large conductance calcium-activated potassium channels with iberiotoxin, a