ライフサイエンスコーパス: calcium-binding

1 at perforin becomes membranolytic only after calcium binding.

2 ile maintaining conservation in N-acetyl and calcium binding.

3 sly unknown determinant of CaV high-affinity calcium binding.

4 The calcium-binding 2EF-hand protein Phl p 7 from timothy gr

5 MPCs displayed increased expression of S100 calcium-binding A4 (S100A4), a protein linked to cancer

6 lix of osteocalcin was selected based on its calcium binding ability and used as substrate for nuclea

7 Nerve injury increased ionized calcium binding adapter molecule 1 (Iba1) and phosphoryl

8 et of rapamycin signaling, levels of ionized calcium-binding adapter molecule 1 and glial fibrillary

9 The panmicroglial marker ionized calcium-binding adapter molecule 1 was decreased in all

10 stic groups did not differ regarding ionized calcium-binding adapter molecule 1+ immunoreactivity for

11 d increased lymphocyte expression of ionized calcium-binding adapter molecule 1, toll-like receptor 2

12 ctivation transcription factor 3 and ionized calcium binding adaptor molecule 1 for neurons and glia,

13 ary acidic protein), and microglial (ionized calcium binding adaptor molecule 1) markers was performe

14 es of amyloid-beta (4G8), microglia (ionized calcium binding adaptor molecule 1), astrocytes (glial f

15 amyloid-beta42 (AN1792): microglial ionized calcium-binding adaptor Iba-1, lysosome marker CD68, mac

16 constitutive astrocytic markers, and ionized calcium-binding adaptor molecule 1 (IBA1) as a constitut

17 neuroinflammatory markers including ionized calcium-binding adaptor molecule 1 (Iba1), glial fibrill

18 spatial distribution and duration of ionized calcium-binding adaptor molecule-1-positive microglial r

19 We ask whether domain interactions and calcium binding affect Protein S folding and potential s

20 The differential calcium binding affinities of the EF-hand domains compar

21 calcium oscillations that uses differential calcium binding affinities to create a robust molecular

22 The interaction does not directly affect the calcium binding affinity of cNTnC.

23 odulins exhibited several-fold reductions in calcium binding affinity.

24 90T in hippocalcin did not affect stability, calcium-binding affinity or translocation to cellular me

25 activity of patients' IgE and mAb102.1F10 to calcium-binding allergens and peptides thereof were stud

26 Calcium binding allosterically activates the enzyme, but

27 3-3 protein-mediated activation of Nth1, and calcium binding, although not required for the activatio

28 On calcium binding, an amphipathic helix of the C-terminal

29 e to the cTn core and site II of cTnC, where calcium binding and dissociation occurs.

30 Calcium binding and dissociation within the cardiac thin

31 TMEM16A is opened by voltage-dependent calcium binding and regulated by permeant anions and int

32 two consensus motifs overlapping the site of calcium-binding and dimerization of the cadherin molecul

33 onents with osteoblast-derived MVs including calcium-binding and extracellular matrix proteins.

34 Annexin A5 belongs to a large family of calcium-binding and phospholipid-binding proteins and ma

35 ese studies reveal central roles for ATP and calcium binding as regulators of calreticulin-substrate

36 two inner loops, CBL1 and CBL2, involved in calcium binding as well as by three outer loops, L1, L2,

37 An essential calcium-binding aspartate residue, Asp307Ala, was disrup

38 fusion studies with intact MUC5B showed that calcium binding at the protein site catalyzed reversible

39 ochemical and physiological basis for RsaA's calcium-binding behavior, which extends far beyond calci

40 ility and conformational dynamics of a model calcium-binding betagamma-crystallin protein, Protein S,

41 The multidomain calcium-binding betagamma-crystallin proteins are partic

42 High-affinity calcium binding by calreticulin is required for optimal

43 P2 levels, which are generated downstream of calcium binding by neuronal calcium sensors such as hipp

44 Indeed, calcium binding by recoverin results in the extrusion of

45 f major UNC-13/Munc13 isoforms contain a non-calcium binding C2A domain that mediates protein homo- o

46 hat PilC1 contains a functional 9-amino-acid calcium-binding (Ca-binding) site with homology to the P

47 nantly colocalized in particles, whereas the calcium-binding calcein label is mainly excluded from th

48 olin second domain, without compromising its calcium binding capacity.

49 nal tail of CRT2 is responsible for its high calcium-binding capacity and function in regulating the

50 strate that lipid membranes have substantial calcium-binding capacity, with several types of binding

51 ps13 and its surprising binding partner, the calcium-binding centrin Cdc31, in trans-Golgi network (T

52 h C. parvum, including calreticulin, a major calcium-binding chaperone in the ER; GRP78/BiP, a prosur

53 Calreticulin is a calcium-binding chaperone that has several functions in

54 Calreticulin is a calcium-binding chaperone that is normally localized in

55 stent with molecular modeling predictions of calcium binding, CIB2 significantly decreased the ATP-in

56 ed primarily the structural integrity of the calcium-binding cluster in LipL32.

57 raphic structure of LipL32 revealed that the calcium-binding cluster of LipL32 includes several essen

58 In conclusion, the calcium-binding cluster of LipL32 plays essential roles

59 ulin, an endoplasmic reticulum (ER) luminal, calcium-binding component of the PLC that is known to bi

60 of Munc13-4 and Rab11, while expression of a calcium binding-deficient mutant of Munc13-4 significant

61 lin mutants that affect ATP or high-affinity calcium binding display prolonged associations with mono

62 ; however, the specific function of the S100 calcium-binding domain in profilaggrin biology is poorly

63 d heterozygous missense mutations in the C2B calcium-binding domain of the gene encoding Synaptotagmi

64 y expressing HA-CaM with impaired individual calcium binding domains as well as HA-CaM lacking the ab

65 ncing the stability of this protein, and the calcium-binding domains of MASS1 are essential for this

66 per 3D configuration of Nth1's catalytic and calcium-binding domains relative to each other, thus sta

67 of NADPH oxidase, NOX5-S, a variant lacking calcium-binding domains, by NOX5 siRNA significantly inh

68 g common collagen-binding domains and unique calcium-binding domains, were synthesized by solid-phase

69 ins a large extracellular N terminus with 35 calcium-binding domains.

70 Synaptotagmin contains two calcium-binding domains: C2A and C2B.

71 reduce levels of proteins within the soluble calcium-binding double C2 domain (Doc2)-like protein fam

72 ound that SMOC-EC, lacking the extracellular calcium binding (EC) domain, inhibited BMP2 signaling, w

73 y its dual ability to bind free calcium, via calcium binding EF-hand domains on the protein, or to bi

74 ered tyrosines, we show that two of the four calcium binding EF-hands dominate the FRET output of TN-

75 ith a semisequential pathway that favors the calcium binding EF-hands of the C-terminal lobe over tho

76 e functionally active if the second (native) calcium-binding EF hand is intact.

77 terminal calmodulin-like domain (CamLD) with calcium-binding EF hands.

78 Within the PC2 Cterm, there is a calcium-binding EF-hand domain, crucial for the calcium-

79 domain adjacent to the kinase domain and two calcium-binding EF-hands at its N terminus.

80 N-terminal regulatory domain containing four calcium-binding EF-hands, a linker loop domain with an a

81 aracterize a rhomboid protease that harbours calcium-binding EF-hands.

82 DAMTS3) and the secreted factor collagen and calcium binding EGF domains 1 (CCBE1) in this process.

83 Collagen- and calcium-binding EGF domain-containing protein 1 (CCBE1)

84 ing N-terminus, extended central array of 11 calcium-binding EGF domains and flexible TGFbeta-binding

85 and compound heterozygosity for collagen and calcium-binding epidermal growth factor domain-containin

86 in the N-terminal linker region of the first calcium-binding epidermal growth factor domain.

87 or Vegfc gene, we searched for collagen- and calcium-binding epidermal growth factor domains 1 (CCBE1

88 hese conformations showed relative increased calcium binding for cTnI QAEH compared to cTnI.

89 ations (apo-form) to a stable structure upon calcium binding (holo-form).

90 Our finding expands our knowledge of calcium binding in extracellular matrix proteins; provid

91 Loss of calcium binding in the D163-D168A mutant was confirmed u

92 Calcium binding induces conformational changes that like

93 The data suggest that SERCA calcium binding induces the pump to undergo a transition

94 Isothermal calorimetry yielded a calcium binding K(d) = 3.8 +/- 1.0 muM and reversible th

95 e kinetic scheme using literature values for calcium-binding kinetics and affinities.

96 EC9-EC10, which show an EC8-9 canonical-like calcium-binding linker, and an EC9-10 calcium-free linke

97 exin V-immunogold staining revealed that the calcium-binding lipid phosphatidylserine (PS) was expose

98 of the trypsinogen activation peptide or the calcium binding loop by Ctrc is unimportant.

99 Surprisingly, mouse Ctrc poorly cleaved the calcium binding loop in all mouse trypsinogens.

100 ates autoactivation, whereas cleavage of the calcium binding loop promotes trypsinogen degradation.

101 Leu81-Glu82 peptide bond is located within a calcium binding loop, and thermodynamic stability of the

102 The three mutations highlight the calcium-binding loop (R1597W), the hydrophobic core arou

103 The structure reveals an atypical calcium-binding loop containing a 13-residue insert.

104 ontrast, R1597W, which resides within the A2 calcium-binding loop, exhibited similar stability in the

105 altered residues in or adjacent to critical calcium binding loops in the calmodulin carboxyl-termina

106 d for the ACm3AC-CaM complex showed that the calcium-binding loops of C-CaM exhibited large fluctuati

107 n secondary structure of the multifunctional calcium-binding messenger protein Calmodulin (CaM) as a

108 that is mediated by an interaction with the calcium-binding messenger protein, calmodulin (CaM), and

109 n (CRT) is an endoplasmic reticulum-resident calcium-binding molecular chaperone that is highly conse

110 agamma-crystallin domain in FgFCO1 devoid of calcium binding motif whose homologous sequences are pre

111 calcium flash activates DUOX via an EF hand calcium-binding motif and thus triggers the production o

112 ion causes an amino acid substitution in the calcium-binding motif of the extracellular cadherin (EC)

113 We also mutated the major calcium-binding motifs within the T3R domain of full-len

114 C domains as well as wild-type Thbs4 and the calcium-binding mutant interacted with Atf6alpha, induce

115 This study aims to investigate calcium-binding myeloid-related protein (MRP)-8/14 in th

116 RTX (Repeat in ToXin) motifs are calcium-binding nonapeptide sequences that are found in

117 nes the temporal availability of calcium for calcium-binding partners and plays a pivotal role in set

118 and provide evidence that lack of secretory calcium-binding phosphoproteins accounts for the evoluti

119 est that the lack of genes encoding secreted calcium-binding phosphoproteins in cartilaginous fishes

120 protection of mAb102.1F10 towards homologous calcium-binding pollen allergens.

121 study revealed that the hydrogels exhibited calcium binding properties in the presence of serum-cont

122 ry and NMR spectroscopy, we investigated the calcium binding properties of a conserved (CaM1) and a d

123 tracellular matrix proteins, we examined the calcium binding properties of the myocilin OLF domain (m

124 at is achieved without drastic alteration of calcium-binding properties.

125 etalloproteinase 9, chitinase 3-like-1, S100 calcium binding protein A8 (S100A8), S100A9, cathepsin B

126 ve cancer phenotype including increased S100 calcium binding protein A8, IL-6, IL-8, and tissue inhib

127 tive excitatory SDH neurons that express the calcium binding protein calretinin (CR).

128 The calcium binding protein calretinin is known to be expres

129 nefits of additionally expressing the mobile calcium binding protein Cb.

130 Calmodulin is the primary calcium binding protein in living cells.

131 ctivity in inhibitory neurons expressing the calcium binding protein parvalbumin (PV) in the mouse pr

132 ss of inhibitory interneurons expressing the calcium binding protein parvalbumin plays a central role

133 nown localization such as TcFCaBP (flagellar calcium binding protein) and TcVP1 (vacuolar proton pyro

134 matricellular protein SMOC (Secreted Modular Calcium binding protein) is conserved phylogenetically f

135 The EF-hand calcium binding protein, parvalbumin, is a major fish al

136 Secretagogin (SCGN), a hexa EF-hand calcium binding protein, plays key roles in insulin secr

137 r target of 2F11 to be Annexin A4 (Anxa4), a calcium binding protein.

138 three lysine residues is stimulated by P300/calcium-binding protein (CBP)-associated factor (PCAF) a

139 We further show that 1q21.3-encoded S100 calcium-binding protein (S100A) family members, mainly S

140 Calcium-binding protein 1 (CaBP1) is a neuron-specific m

141 In neurons, binding of calmodulin (CaM) or calcium-binding protein 1 (CaBP1) to the CaV1 (L-type) v

142 Ca(2+) sensor proteins, calmodulin (CaM) and calcium-binding protein 1 (CaBP1), via multiple, partial

143 vels of an age-associated gene, Sarcoplasmic calcium-binding protein 1 (SCP-1).

144 n, calbindin, calretinin, N-terminal EF-hand calcium-binding protein 1, cholecystokinin, reelin, or a

145 rofiling reveals an increase of the neuronal calcium-binding protein 2 (NECAB2) in diseased neurons.

146 Recently, the calcium-binding protein 39 (Cab39) has emerged as a bind

147 Calcium-binding protein 7 (CaBP7) is a member of the cal

148 otein (CRP), serum amyloid A (SAA), and S100 calcium-binding protein A12 (S100A12).

149 upregulation of the metastatic mediator S100 Calcium-binding protein A4 (S100A4) (1.78-fold, P<0.05).

150 ion using principal component analysis, S100 calcium-binding protein A4 (S100A4) was aligned to a pri

151 se levels trigger neutrophil release of S100 calcium-binding protein A8/A9 (S100A8/A9), which binds t

152 S100 calcium-binding protein A9 (S100A9) has previously been

153 ecific transcripts mannose receptor and S100 calcium-binding protein A9, which significantly discrimi

154 and modulates the interactions between this calcium-binding protein and the T1 domain of the Kv4.3 c

155 els of the astroglial injury biomarker S-100 calcium-binding protein B were also increased in players

156 marker concentrations of total tau and S-100 calcium-binding protein B were measured immediately afte

157 Total tau, S-100 calcium-binding protein B, and neuron-specific enolase c

158 tween the sexes, using the expression of the calcium-binding protein calbindin (CB) during embryonic

159 The calcium-binding protein calbindin-D28k is critical for h

160 bility group (HMG) box) proteins require the calcium-binding protein calmodulin (CaM) for optimal nuc

161 ecule, force-spectroscopy experiments of the calcium-binding protein calmodulin and explain it in a s

162 via the binding of the ubiquitous eukaryotic calcium-binding protein calmodulin to the cytoplasmic ta

163 The calcium-binding protein calreticulin (CRT) regulates pro

164 he vertical eye movement system contains the calcium-binding protein calretinin (CR).

165 Vps13p must be in complex with the small calcium-binding protein Cdc31p to be active.

166 cific Ca(V)1 subtype or distribution of each calcium-binding protein did not associate with those reg

167 The calcium-binding protein downstream regulatory element an

168 S100B is a calcium-binding protein expressed in, and secreted by, a

169 derived, but differ in morphology, location, calcium-binding protein expression, synaptic connectivit

170 This calcium-binding protein localizes to the junctional SR (

171 We have discovered that the calcium-binding protein nuclebindin-1 (NUCB1) is a novel

172 Positive immunoreactivity to the calcium-binding protein parvalbumin (PV) and nitric oxid

173 by two populations of neurons containing the calcium-binding protein parvalbumin (PV): local inhibito

174 ortical GABAergic interneurons expresses the calcium-binding protein parvalbumin and plays a critical

175 ssurance acted through the regulation of the calcium-binding protein PAT-10.

176 -spiking interneuron clusters expressing the calcium-binding protein Pvalb were identified, one co-ex

177 We used antibodies against the calcium-binding protein recoverin and the carbohydrate e

178 Nuclear expression of the calcium-binding protein S100A4 is a biomarker of increas

179 The calcium-binding protein S100A4 is expressed at elevated

180 correlated with the expression of the small calcium-binding protein S100A4.

181 ression of Cav1, which then acts through the calcium-binding protein S100P to promote metastasis.

182 In the present study the calcium-binding protein secretagogin was localized in a

183 otassium channel interacting protein 3) is a calcium-binding protein that binds at the N terminus of

184 matrix protein 1 (DMP1) is a non-collagenous calcium-binding protein that plays a critical role in bi

185 m and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as

186 alcium-dependent sequestration of PID by the calcium-binding protein TOUCH3 (TCH3).

187 Calmodulin is a calcium-binding protein ubiquitous in eukaryotic cells,

188 Here we show that S100A11, a calcium-binding protein upregulated in a variety of meta

189 interneurons, which do not contain any known calcium-binding protein(s), kappafixed amounted to only

190 ine kinase, myosin light chain, sarcoplasmic calcium-binding protein, and hemocyanin are the most rel

191 eraldehyde-3-phosphate dehydrogenase (GPDH), calcium-binding protein, and phosphoglycerate mutase wer

192 breast cancer cells is also modulated by the calcium-binding protein, calmodulin (CaM).

193 verse genetics to test the role of the small calcium-binding protein, centrin2, in ciliogenesis.

194 fin cells, but the role of a closely related calcium-binding protein, Doc2b, remains enigmatic.

195 he Tc1 include increased levels of the S100B calcium-binding protein, mTOR proteins RAPTOR and P70S6,

196 ulation of projection neurons containing the calcium-binding protein, parvalbumin (PV).

197 ically projecting neurons, which contain the calcium-binding protein, parvalbumin (PV).

198 that the selective co-expression of another calcium-binding protein, secretagogin (Scgn), separates

199 -like domain beta (DOC2B) gene encodes for a calcium-binding protein, which is involved in neurotrans

200 f the gene encoding SMOC-2 (secreted modular calcium-binding protein-2), which has been shown to syne

201 Calcium-binding protein-7 (CaBP7) is a phosphatidylinosi

202 This process is initiated by the calcium-binding protein-apoptosis-linked gene (ALG)-2.

203 is structurally stabilized by calmodulin, a calcium-binding protein.

204 Neurons expressing the calcium binding proteins (CaBPs) parvalbumin (PV) and ca

205 These data support the notion that calcium binding proteins are differentially distributed

206 Centrins are calcium binding proteins that belong to the EF-hand supe

207 (Ocm), a member of the parvalbumin family of calcium binding proteins, is expressed predominantly by

208 cell adhesion molecules, neuropeptides, and calcium binding proteins.

209 Calcium-binding proteins (CaBPs) such as parvalbumin are

210 se to hyperglycemia, neutrophil-derived S100 calcium-binding proteins A8/A9 (S100A8/A9) interact with

211 thalamic neurons that do not contain typical calcium-binding proteins and do not project to other par

212 ith existing classification methods based on calcium-binding proteins and firing behavior.

213 Thus, with respect to the expression of calcium-binding proteins and neuropeptides, GINs are sur

214 amined expression of Ca(V)1 subtypes and the calcium-binding proteins calbindin, calmodulin and calre

215 ctal cells were found to be negative for the calcium-binding proteins calbindin, parvalbumin, or calr

216 compared with the apo states of the EF-hand calcium-binding proteins calmodulin, S100B, and calbindi

217 The calcium-binding proteins calretinin (CR) and calbindin-D

218 that up to 1% of all identified multidomain calcium-binding proteins contain a similarly highly char

219 Because of the many different calcium-binding proteins distributed throughout cells, s

220 EhCaBP1, one of the calcium-binding proteins from Entamoeba histolytica, is

221 nalyze the immunohistochemical expression of calcium-binding proteins in the dorsal thalamus of Fmr1

222 of GABAergic neurons identified by distinct calcium-binding proteins may exert unique roles in the p

223 ar components include the EF-hand-containing calcium-binding proteins mitochondrial calcium uptake 1

224 to GABAergic interneuron subtypes expressing calcium-binding proteins parvalbumin, calbindin, or calr

225 S100A8 and S100A9 are calcium-binding proteins predominantly expressed by neut

226 In the habenula, these calcium-binding proteins revealed right-left asymmetry o

227 ne signaling, notably the heterodimeric S100 calcium-binding proteins S100a8 and S100a9.

228 Interneuron markers using calcium-binding proteins showed that LS GABAergic neuron

229 Calcium-binding proteins such as parvalbumin and calbind

230 r to derive from matrix vesicles enriched in calcium-binding proteins that are released by cells with

231 S100A4 is a member of the S100 family of calcium-binding proteins that is directly involved in tu

232 n the amount of both Ca(V)1 subtypes and the calcium-binding proteins were found throughout the brain

233 calcium indicators are fusions of endogenous calcium-binding proteins whose functionality in vivo may

234 Centrins are a family of small, calcium-binding proteins with diverse cellular functions

235 antibodies against G-protein alpha subunits, calcium-binding proteins, and general neuronal markers,

236 that includes the AMPA receptor, integrins, calcium-binding proteins, and, surprisingly, the myelin

237 that CUL3 and its adaptor KLHL12 require two calcium-binding proteins, PEF1 and ALG2, for recognition

238 95% of the axonemal tektins, and >95% of the calcium-binding proteins, Rib74 and Rib85.5, whose human

239 It involves two major calcium-binding proteins, the voltage-gated calcium chan

240 s signals as inferred by the accumulation of calcium-binding proteins.

241 In dentate granule cells, the calcium binding ratio (kappa) after complete washout of

242 ncluding the phosphatase catalytic site, the calcium-binding region 3 (CBR3) loop, the Calpha2 loop a

243 ed that multiple Ca(2+) ions bind within the calcium-binding regions, activating perforin with respec

244 Chatterjee and colleagues, we show that the calcium-binding residues of LapG, D134 and E136, which a

245 identify four acidic amino acids as putative calcium-binding residues.

246 able to interact with LapD, indicating that calcium binding results in LapG adopting a conformation

247 ggest a mechanism for allosteric activation: calcium binding results in partial closure and ordering

248 metal-chelating antimicrobial protein of the calcium-binding S100 family that is produced and release

249 NF, MHC, immunoglobulin-binding Fc receptor, calcium-binding S100, matrix metalloproteinase, tissue i

250 ng helix across the activation pocket to the calcium binding site and are embedded in elements of sec

251 well as in the vicinity of the high affinity calcium binding site and the A knob polymerization pocke

252 as was seen with TBSV, CNV appears to have a calcium binding site between the subunits around the qua

253 ), affect residues at or near the structural calcium binding site Ca-1.

254 e, reside at a significant distance from the calcium binding site in cardiac troponin C, and do not a

255 A structures, with a single highly conserved calcium binding site in each monomer.

256 We further identified a calcium binding site in proximity to the catalytic zinc.

257 mited access to chelators, indicate that the calcium binding site is largely buried in the interior o

258 study reveals an unprecedented high affinity calcium binding site within myoc-OLF.

259 I are important for the stabilization (first calcium binding site) of its zymogenic form and the poss

260 the same residue, leading to the loss of the calcium binding site.

261 ity produced by the high charge density of a calcium binding site.

262 plicating a critical role for the A2 type II calcium-binding site and the A2A3 linker in the activati

263 ealed a previously uncharacterized catalytic calcium-binding site in hSCAN-1, which elucidates the un

264 exes with different ligands and identified a calcium-binding site in the S1 pocket of APA.

265 pose the scissile bond and is regulated by a calcium-binding site within A2.

266 subfamily of TRP channels and a well-defined calcium-binding site within the intracellular side of th

267 ymeric MUC5B revealed a single high affinity calcium-binding site, distinct from multiple low affinit

268 reticulin, in proximity to the high-affinity calcium-binding site, that are important for high-affini

269 le chronological submolecular changes within calcium binding sites can bring about the detailed trans

270 Cells expressing CaM with all calcium binding sites impaired died with kinetics simila

271 2 channel function, we altered the number of calcium binding sites in hPC2.

272 calcium biosensors with a reduced number of calcium binding sites per sensor.

273 In addition, secondary calcium binding sites were identified.

274 ic acid residues 3394, 3556, and 3674 in the calcium binding sites.

275 idic region containing multiple low-affinity calcium binding sites.

276 fic immunotherapy based on mutation of the 2 calcium-binding sites have been developed.

277 ults suggest that the number and location of calcium-binding sites in the EF hand senses the concentr

278 main interactions and define three potential calcium-binding sites that are likely important for regu

279 ence, often featuring linkers with conserved calcium-binding sites that confer mechanical strength to

280 Synaptotagmin-1 (SYT1) is a calcium-binding synaptic vesicle protein that is require

281 at the EF-hand changes its conformation upon calcium binding, the central coiled coil forms an antipa

282 Furthermore, C2B inhibition is relieved by calcium binding to C2B, while the neighboring C1 domain

283 calcium-activated K(+) channels are gated by calcium binding to calmodulin (CaM) molecules associated

284 We discovered that calcium binding to calmodulin increases the binding affi

285 DP destabilize enthalpy-driven high-affinity calcium binding to calreticulin.

286 Calcium binding to either domain favors an "open" confor

287 By analyzing the dynamics of calcium binding to probe molecules and the effects of th

288 on with the plasma membrane on activation by calcium binding to synaptotagmin.

289 It is established that calcium binding to Syt1 triggers vesicle fusion and rele

290 Contraction of heart muscle is triggered by calcium binding to the actin-containing thin filaments b

291 eable channel whose activity is regulated by calcium binding to the C-terminal domain of PC2 (PC2 Cte

292 Muscles are usually activated by calcium binding to the calcium sensory protein troponin-

293 Calcium binding to the EF-hand domains of CP increases t

294 We find that calcium binding to the EF-hand domains promotes autophos

295 NMR data demonstrate that calcium binding to the regulatory module generates subst

296 Calcium binding to the troponin C (TnC) subunit causes a

297 Calcium binding to thin filaments is a major element con

298 ated to the sensitivity and cooperativity of calcium binding to troponin C and the activation and rel

299 Dysferlin is a calcium-binding transmembrane protein involved in membra

300 However this included Cabyr, the calcium-binding tyrosine phosphorylation-regulated prote