ライフサイエンスコーパス: calcium-sensitive

1 ly correlated with cAMP accumulation and was calcium sensitive.

2 , the co-immunoprecipitation was found to be calcium-sensitive.

3 g of plant actin by human T-plastin, a known calcium-sensitive actin-crosslinking protein.

4 lin, but not Xenopus ADF/cofilin, eliminates calcium-sensitive actin-filament shortening.

5 -type calcium channels, and secondarily, the calcium-sensitive activity of Maxi-K channels, rendering

6 Classically, P(open) is regulated by a calcium-sensitive adaptation mechanism in which lowering

7 Spermidine efflux is also calcium sensitive, and removal of external calcium incre

8 The in vivo function of CapG, a calcium-sensitive barbed end capping protein and member

9 The calcium-sensitive binding of calmodulin to myosin-1c may

10 cell populations by cotransfection with the calcium-sensitive, bioluminescent protein aequorin and b

11 elation showed that cTn myofibrils were more calcium sensitive but less cooperative (pCa50 = 6.14, nH

12 ar glutamate levels was determined to be 39% calcium-sensitive by lowering the calcium concentration

13 These findings provide evidence that the calcium-sensitive CBL and CIPK families together with 2C

14 ctor-transfected control, demonstrating that calcium-sensitive chloride channel (CLCA) expression is

15 lcium signals were studied using Fura Red or calcium-sensitive Cl(-) current.

16 An antagonist of calcium-sensitive Cl- channels (CaCC), niflumic acid, ha

17 We also show that RP2 forms a calcium-sensitive complex with the autosomal dominant po

18 50(-/-)) mice and demonstrated that both the calcium-sensitive conductance and dye influx were absent

19 in, and this interaction is regulated by the calcium-sensitive conformation of COMP/TSP5; interaction

20 e three-dimensional molecular topography and calcium-sensitive conformational changes of Connexin40 h

21 d three-dimensional molecular topography and calcium-sensitive conformational changes of individual h

22 that would not easily explain the advent of calcium-sensitive currents at embryonic day (E)18-19.

23 he current view, which has focused mainly on calcium-sensitive dehydrogenases as the target for the a

24 zers we bring two droplets, one containing a calcium sensitive dye and the other calcium chloride, in

25 actory bulb, we loaded receptor neurons with calcium-sensitive dye and imaged odorant-evoked response

26 ated hippocampal slices were loaded with the calcium-sensitive dye Calcium Green-1 and the responses

27 dies, single M1WT3 CHO cells loaded with the calcium-sensitive dye fluo-4 AM were captured; exposure

28 Further, using the calcium-sensitive dye Fluo-4, we conducted real-time ima

29 y in dopaminergic PC12 cells loaded with the calcium-sensitive dye Fura-2.

30 intracellular calcium to nicotine using the calcium-sensitive dye fura-2.

31 measured by ratiometric techniques with the calcium-sensitive dye fura-2.

32 m levels were measured using the fluorescent calcium-sensitive dye, Calcium Green-1 3000 mw dextran c

33 , measured by flow cytofluorometry using the calcium-sensitive dye, Fluo-3.

34 s (APs) from multiple dendrites using either calcium-sensitive dye, voltage-sensitive dye or both.

35 Using a calcium-sensitive dye, we observed a dramatic increase i

36 ns at single-cell and population levels with calcium-sensitive dye.

37 Advances in fluorescence microscopy and calcium sensitive dyes has led to the routine quantifica

38 video and confocal laser microscopy with the calcium-sensitive dyes fluo-3 and fura-2 were used to st

39 ard cells has previously required loading of calcium-sensitive dyes using invasive and technically di

40 parvalbumin, calbindin, calretinin, and the calcium-sensitive enzyme calcium/calmodulin-dependent ki

41 holipases A2 (cPLA2s) consist of a family of calcium-sensitive enzymes that function to generate lipi

42 nce of net plateau currents by modulation of calcium-sensitive exchange and ion channel currents.

43 that dysregulation of ceramide pathways and calcium sensitive exocytosis underlies seizures and larg

44 interacting with the doc2a gene, encoding a calcium-sensitive exocytosis regulator, a genetic intera

45 dynamics during convergent extension using a calcium-sensitive fluorescent dye and a novel confocal m

46 ; imaging of nerve terminals loaded with the calcium-sensitive fluorescent dye fluo-3 showed no signi

47 Isolated PMNs were loaded with the calcium-sensitive fluorescent dye fura-2.

48 [Ca2+](i) was assessed using the calcium-sensitive fluorescent dye fura-2.

49 in the perfused mouse heart loaded with the calcium-sensitive fluorescent dye Rhod-2.

50 Fluorescence measurements using the calcium-sensitive fluorescent dye, calcium green 5N, con

51 Calcium-sensitive fluorescent dyes indicated that such c

52 onist-receptor interaction is measured via a calcium-sensitive fluorescent probe (fura-2) and a fluor

53 Confocal microscopy in combination with the calcium-sensitive fluorescent probe fluo-3 was used to s

54 lls were isolated, plated and preloaded with calcium-sensitive fluorescent probe, Indo-1AM.

55 A recent study in which a calcium-sensitive fluorescent protein was expressed in t

56 croscopy with the specific expression of the calcium-sensitive fluorescent protein, G-CaMP.

57 Using a calcium-sensitive fluorochrome and digital multichannel

58 Infusion of Fluo-4 AM, a calcium-sensitive fluorochrome, into the mouse circulati

59 lular calcium levels were monitored with the calcium-sensitive fluorophore fura-2 before and after tr

60 s visualized via selective expression of the calcium-sensitive fluorophore GCaMP in layer 2/3 and 5 e

61 the ROS preparations was measured using the calcium-sensitive fluorophore Quin-2.

62 naptic calcium transients were measured with calcium-sensitive fluorophores, and delayed release was

63 ng I(Ca)pre optically in boutons loaded with calcium-sensitive fluorophores.

64 le motion indicates the operation of a rapid calcium-sensitive force generator linked to the gating o

65 dc42 activation through interaction with the calcium sensitive GTPase scaffolding protein IQGAP1, mai

66 nd RetGC2) in rod and cone photoreceptors by calcium-sensitive guanylyl cyclase activating proteins (

67 Two calcium-sensitive guanylyl cyclase activating proteins (

68 ormed from connexin 38 (Cx38), and produce a calcium-sensitive (Ic) current that is inhibited by exte

69 reviously and hypothesized to be caused by a calcium-sensitive inactivation of a potassium channel.

70 We also detected calcium-sensitive increased TRPV1 activity after TRPA1 a

71 Cerebratulus lacteus were injected with the calcium-sensitive indicator calcium green dextran and/or

72 sands of neurons of the visual cortex with a calcium-sensitive indicator in vivo.

73 Measurements of [Ca]res using fluorescent calcium-sensitive indicators revealed that [Ca]res decay

74 e in endothelial cell (EC) calcium activates calcium-sensitive intermediate and small conductance pot

75 The results indicate the presence of calcium-sensitive intracellular mechanisms involved in t

76 tivators of the ATP sensitive K (K(ATP)) and calcium sensitive K (K(ca)) channel following fluid perc

77 ctivators of ATP sensitive K(+) (K(ATP)) and calcium sensitive K(+) (K(ca)) channels following fluid

78 Although nitric oxide (NO) and calcium sensitive K+ channel (Kca) activation contribute

79 ion of calcium (Ca(2+)) sparks and transient calcium-sensitive K(+) (K(Ca)) currents by acute changes

80 duction of cAMP and subsequent activation of calcium-sensitive K+ (K(Ca2+)) channels by this second m

81 Human large-conductance voltage- and calcium-sensitive K+ (maxi KCa) channels are composed of

82 Voltage-dependent and calcium-sensitive K+ (MaxiK) channels are key regulators

83 lease of cAMP, which, in turn, activates the calcium sensitive (K(ca)) and the ATP-dependent K(+) (K(

84 Activation of calcium sensitive (K(ca)) K channels and cAMP contribute

85 while cAMP activates both the K(ATP) and the calcium sensitive (K(ca)) K(+) channel to elicit vasodil

86 cterize the role of ATP sensitive (KATP) and calcium sensitive (Kca) channel activation in hypotensio

87 olic calcium and decreases activation of the calcium-sensitive kinase calcium-calmodulin-dependent pr

88 This helix has been postulated to serve as a calcium-sensitive latch, keeping gelsolin inactive.

89 ound that myoferlin binds phospholipids in a calcium-sensitive manner that requires the first C2A dom

90 rmation and SNARE-mediated lipid mixing in a calcium-sensitive manner.

91 regulate CDH23 trafficking/localization in a calcium-sensitive manner.

92 for their ability to bind phospholipid in a calcium-sensitive manner.

93 own that Cabin1 is associated with MEF2 in a calcium-sensitive manner; activated calmodulin binds to

94 pus extracts, Listeria tail lengths are also calcium-sensitive, markedly shortening on addition of ca

95 dent in vivo and inhibitable in vitro by the calcium-sensitive MEF2 repressor Cabin 1.

96 as been shown to be necessary for efficient, calcium-sensitive, membrane resealing.

97 [Ca2+]i were recorded using either fura-2 or calcium-sensitive microelectrodes.

98 crophage, coupling membrane capacitance with calcium-sensitive microfluorimetry.

99 Furthermore, unlike wild type G1-G3, calcium-sensitive mutants of G1-G3 acquired closed shape

100 contributed to the production of NO through calcium-sensitive nitric-oxide synthase enzymes present

101 d that this persistent firing is driven by a calcium-sensitive nonselective cation current.

102 The calcium-sensitive nuclear factor of activated T cells (N

103 f activated T cells) signaling, an important calcium sensitive pathway controlling bone formation.

104 K506, and has been implicated in a number of calcium-sensitive pathways in the nervous system, includ

105 ed phenotypes similar to those observed with calcium-sensitive, Pet- vna mutants defective in vacuole

106 egulator of the hypertrophic response is the calcium-sensitive phosphatase calcineurin.

107 egulator of cardiomyocyte hypertrophy is the calcium-sensitive phosphatase calcineurin.

108 nstream signaling events are mediated by the calcium-sensitive phosphatase calcineurin; inhibition of

109 ysferlin C2A domain and demonstrated reduced calcium-sensitive phospholipid binding.

110 tein which we have named CSPP28 based on its calcium-sensitive phosphorylation.

111 were fused at their carboxyl terminus to the calcium-sensitive photoprotein aequorin.

112 Aequorin is a calcium-sensitive photoprotein originally obtained from

113 Using knock-out mice of the calcium-sensitive PKC isoforms (PKC(Ca)), we find that e

114 nduced, TRPA-1-mediated calcium influx and a calcium-sensitive PKC that signals to the transcription

115 -PMA, which does not activate PKC) recruited calcium-sensitive PKCalpha and novel PKCdelta and PKCeps

116 eries is by activation of large-conductance, calcium-sensitive potassium (BK(Ca)) channels by local C

117 The large conductance calcium-sensitive potassium (BK) channel is widely expre

118 Modulation of calcium-sensitive potassium (BK) channels by oxygen is i

119 eurohypophysis potentiates large-conductance calcium-sensitive potassium channels (BK), contributing

120 e elevation in cytosolic calcium potentiated calcium-sensitive potassium channels (sK) activated by a

121 y between voltage-gated calcium channels and calcium-sensitive potassium channels, they can be very d

122 However, cell-specific delivery of calcium-sensitive probes in vivo remains problematic.

123 switches are ancient devices for controlling calcium-sensitive processes.

124 reduction is reproduced by inhibition of the calcium-sensitive protease calpain in wild-type neurons

125 on their dephosphorylation by calcineurin, a calcium-sensitive protein phosphatase and the inhibitory

126 ts lacking tropomyosin regions 2-3 exhibited calcium-sensitive regulation in in vitro motility and my

127 In addition, the unimpaired calcium-sensitive regulation of cleaved actin indicates

128 rved at higher cellular [Ca(2+)], indicating calcium-sensitive regulation of these processes.

129 vator (CAMTA) family of proteins function as calcium-sensitive regulators of gene expression in multi

130 studies show its calcium dependence, but the calcium-sensitive regulatory cascades have not been defi

131 d cardiac troponins C and I (Tnni3), forms a calcium-sensitive regulatory complex within sarcomeres.

132 similar to the partial assembly that engages calcium-sensitive regulatory machinery.

133 lasmic free calcium in host root hairs using calcium-sensitive reporter dyes.

134 propose a model in which otoferlin acts as a calcium-sensitive scaffolding protein, localizing SNARE

135 Colorimetric calcium-sensitive sensor films were deposited onto a DVD

136 entrations in T cells, potentially affecting calcium-sensitive signaling pathways.

137 and Asp-61), together with the intra-domain calcium-sensitive sites in villin, regulate actin depoly

138 chemically and functionally characterize the calcium-sensitive sites in villin.

139 modules constitute a dynamic and interactive calcium-sensitive structure in which a distortion at one

140 ic voltage-gated calcium entry to downstream calcium-sensitive synaptic growth regulators provides an

141 w show that the tandem C2 domains of several calcium-sensitive synaptotagmin isoforms tested, includi

142 r soluble sperm factors and in turn regulate calcium-sensitive targets required for subsequent develo

143 lin D1 by post-translational modification of calcium sensitive transcription factor CREB.

144 rvations indicate that CBP can function as a calcium-sensitive transcriptional coactivator that may a

145 AC4, MITR, and Cabin1 constitute a family of calcium-sensitive transcriptional repressors of MEF2.

146 tected, despite their position distal to the calcium-sensitive tryptophan, with a volume change of +2

147 teine did inhibit the phosphorylation of the calcium sensitive tyrosine kinases PYK2 and Src, effects

148 Calcium-sensitive tyrosine kinase Pyk2 has been implicat

149 However, the activation of the calcium-sensitive tyrosine kinase PYK2, which occurred i

150 of classical PKC and the recently described calcium-sensitive tyrosine kinase PYK2.

151 Y mutation at low (<10(-7) m) calcium but is calcium-sensitive with a 1.6-fold increase at high ( app