ライフサイエンスコーパス: calf thymus DNA

1 ctroscopy of 160 base pair (bp) fragments of calf thymus DNA.

2 iated by adding a large excess of unlabelled calf thymus DNA.

3 unperturbed by complexation of the drug with calf thymus DNA.

4 xyuracil, compared to commercially available calf thymus DNA.

5 t interact with plasmid (pBR322) DNA or with calf thymus DNA.

6 ouble-stranded nucleic acid homopolymers and calf thymus DNA.

7 than unimmunized mice or mice immunized with calf thymus DNA.

8 ate the ethanol-induced B to A transition in calf thymus DNA.

9 compared to heat denatured, single stranded calf thymus DNA (0.007 endotoxin/microg DNA).

10 With calf thymus DNA, 5-guanidino-4-nitroimidazole was dose-d

11 e formation of 8 major and at least 10 minor calf thymus DNA adducts.

12 -forming cationic lipids are able to protect calf thymus DNA against denaturation at 100 degrees C.

13 asure the binding constants between purified calf thymus DNA and a library of designed tetrapeptides

14 he ability to displace ethidium bromide from calf thymus DNA and are rapidly taken up by F98 glioma c

15 ir ability to displace ethidium bromide from calf thymus DNA and are rapidly taken up in vitro by F98

16 Calf thymus DNA and DNA from the livers of MNU-treated S

17 to identify BPQ adducts formed in vitro with calf thymus DNA and DNA homopolymers.

18 Calf thymus DNA and DNA isolated from cultured HeLa cell

19 vels of the alpha-anomer of dG (alpha-dG) in calf thymus DNA and in DNA isolated from mouse pancreati

20 -cdGuo and (5'S)-8,5'-cdGuo were measured in calf thymus DNA and in DNA samples isolated from three d

21 OLN had DNA polymerase activity on activated calf thymus DNA and on a singly primed template.

22 -kDa Mg(2+)-dependent nuclease that degrades calf thymus DNA and plasmid DNA.

23 nity of the compounds was also studied using calf thymus DNA and poly(dA-dT).

24 nmol/min/mg when assayed in the presence of calf thymus DNA and the four deoxyribonucleoside triphos

25 lastic glycopeptide bleomycin A2 (Fe-BLM) to calf thymus DNA and the self-complementary oligonucleoti

26 ion of the racemic syn- and anti-BgCDEs with calf thymus DNA and with purine deoxyribonucleoside-3'-p

27 uantum yield (approximately 0.5, bound to ds calf thymus DNA) and large molar extinction coefficient

28 Binding to calf thymus DNA as assessed by differential pulse polaro

29 In the absence of polyamines, calf thymus DNA assumed a diffused, planar cholesteric p

30 tudies show that, after 18 h incubation with calf thymus DNA at a 5:1 DNA/ligand ratio, it increases

31 In fact, controls carried out with calf thymus DNA, betaNAD(+), PARP-1, and automodified PA

32 achieve when it is bound to d(CGCGCG) or to calf thymus DNA but not when bound to d(ATATAT).

33 The measurement of 8-OH-Gua in calf thymus DNA by GC/isotope-dilution MS (GC/IDMS) usin

34 ld be demonstrated that, although 3 binds to calf-thymus DNA by intercalation, the biological effects

35 Rabbits were immunized with calf thymus DNA, chemically modified with alpha-acetoxyt

36 es but not by pUC nor Bacillus subtilis DNA; calf thymus DNA competed at higher concentrations.

37 bound to double-stranded poly(dABrdU) and to calf thymus DNA (CT DNA) and the complexes characterized

38 monostyryl derivativatives intercalate into calf thymus DNA (ct DNA), whereas photocyclization produ

39 ity are observed upon addition of 100 microM calf thymus DNA (ct-DNA).

40 ands regulate their ability to interact with calf thymus DNA (ctDNA) through an intercalative mode.

41 Interactions of the complex with calf thymus DNA (ctDNA) were conducted with a flow-cell

42 ost of the thymidine 5'-monophosphate (TMP), calf thymus DNA (CTDNA), and plasmid DNA (PLDNA) analyse

43 The presence of single-stranded calf thymus DNA (equimolar with duplex) eliminated the t

44 lished by derivatizing adducts isolated from calf thymus DNA exposed to AAAF.

45 The substrate used was calf-thymus DNA exposed to gamma-radiation in N2O-satura

46 nance (NMR) studies of the interactions with calf thymus DNA for the three molecules.

47 For comparison, we also studied calf thymus DNA for which the hydration exhibits similar

48 lysis of the binding of iodoHoechst 33342 to calf thymus DNA gave an equilibrium association constant

49 3))(6)(3+), with 160 and 3000-8000 bp length calf thymus DNA has been investigated by circular dichro

50 160 base pair (bp) fragments of nucleosomal calf thymus DNA have been probed by the method of Raman

51 4-yl)diphenylporphine ions on the surface of calf thymus DNA have been studied using several spectros

52 (max)) of 632 nm, while the bound dyes (with calf thymus DNA) have electronic transitions with lambda

53 ologen (BV) with single- and double-stranded calf-thymus DNA immobilized onto gold electrodes have be

54 e betaine (GB) and urea with mononucleosomal calf thymus DNA in aqueous salt solutions are characteri

55 hydrolysis of the epoxide was accelerated by calf thymus DNA in the range of pH 6-8, with a larger en

56 -enhanced binding of the N-hydroxylamines to calf thymus DNA in vitro.

57 r 7-methylguanine (7-meG) from 3H-methylated calf thymus DNA in vitro.

58 The levels of N7-MedG and 06-MedG in calf thymus DNA increased with MNU concentration and inc

59 position of pV is reduced in the presence of calf thymus DNA, indicating that a decomposition product

60 nsfer of the electronic excitation energy in calf thymus DNA is studied by time-resolved fluorescence

61 NA interactions results in high affinity for calf thymus DNA (Kapp approximately 5 x 10(7) M(-1)).

62 the epoxide forms a reversible complex with calf thymus DNA (Kd = 0.43 mg ml-1, or 1.4 mM monomer eq

63 Further, the DNA adduction studies with the calf thymus DNA led to a mixture of dA and dG adducts fo

64 e binding to mononucleosomal (160 base-pair) calf thymus DNA of a high charge density (compact) 5-res

65 ng DPPH radical) and biocompatibility (using calf-thymus DNA) of curcumin-loaded mixed surfactant for

66 polynucleotides, of hexamine cobalt(III) to calf thymus DNA, of polyamines to T7 DNA, of oligolysine

67 the t(m) depression, whereas double-stranded calf thymus DNA only altered the t(m) of the 28-mer dupl

68 When calf thymus DNA or oligonucleotides were reacted with pe

69 ocytes in NZB/NZW mice injected with EC DNA, calf thymus DNA, or an immune active oligonucleotide.

70 y an excess of free aptamer but not by tRNA, calf thymus DNA, or transferrin.

71 iologically reactive metabolite and binds to calf thymus DNA (pH 5.0 or 7.0) to form the N-(deoxyguan

72 e in primer extension reactions catalyzed by calf thymus DNA polymerase (pol) alpha and human DNA pol

73 36-mer primer/template DNA by purified fetal calf thymus DNA polymerase (pol) delta was examined usin

74 catalyzed by Klenow fragment exo- (Kf exo-), calf thymus DNA polymerase alpha (pol alpha) or human DN

75 oth adducts primarily blocked replication by calf thymus DNA polymerase alpha at the modified base, w

76 t of Escherichia coli DNA polymerase I or by calf thymus DNA polymerase alpha.

77 amide gel electrophoresis, is formed between calf thymus DNA polymerase delta (pol delta) and synthet

78 ear antigen (PCNA) promotes DNA synthesis by calf thymus DNA polymerase delta (pol delta) past severa

79 e 8-oxo-7,8-dihydroguanine (8-oxoG) by fetal calf thymus DNA polymerase delta (pol delta) was examine

80 with exogenous template-primer and purified calf thymus DNA polymerase delta (pol delta).

81 Calf thymus DNA polymerase delta also fully restored mis

82 ypeptides were isolated with highly purified calf thymus DNA polymerase delta by conventional chromat

83 mmunoprecipitated with human p50, as well as calf thymus DNA polymerase delta heterodimer, but not wi

84 activity and to enhance the processivity of calf thymus DNA polymerase delta holoenzyme similar to c

85 lls, in contrast to the native heterodimeric calf thymus DNA polymerase delta, is not responsive to s

86 antibodies (13D5) inhibited the activity of calf thymus DNA polymerase delta.

87 le of NTP concentration in determining where calf thymus DNA primase synthesizes a primer on a DNA te

88 bacterial DNA, in comparison to 10 microg of calf thymus DNA, resulted in a fourfold increase in the

89 olution (rho(v)(90) = 0.13 at 450 nm) and on calf thymus DNA (rho(v)(90) = 0.20 at 454 nm), and chlor

90 cro-dG adducts in acrolein (10-fold)-treated calf thymus DNA showed approximately 830 lesion/10(6) DN

91 ochromate(V) with pUC19 DNA, single-stranded calf thymus DNA (ss-ctDNA), a synthetic oligonucleotide,

92 ts were formed in a dose-dependent manner in calf thymus DNA subjected to photooxidation in the prese

93 enhanced thermal denaturation temperature of calf thymus DNA ( T m), and cytotoxicity is well documen

94 -BD lesions (intrastrand and interstrand) in calf thymus DNA treated separately with S,S-, R,R-, or m

95 In enzymatic digests of calf thymus DNA treated with 2, three adducts were ident

96 DNA upon exposure to gamma- or X-rays and in calf thymus DNA treated with Fenton reagents.

97 ation of high molecular weight and sonicated calf thymus DNA, two therapeutic oligonucleotides, and p

98 d to the analysis of etheno-dC in commercial calf thymus DNA, untreated mouse liver, and untreated ra

99 tandem MS confirmation of their formation in calf thymus DNA upon diazoacetate exposure, and the prep

100 ethylated derivatives of thymidine formed in calf thymus DNA upon exposure to diazoacetate.

101 yguanosine moiety and commercially available calf thymus DNA using this technique.

102 AP sites induced in plasmid or genomic calf thymus DNA via mild depurination or by simple incub

103 say, the rate of spontaneous depurination of calf thymus DNA was determined.

104 of small fluorescent organic molecules with calf thymus DNA was developed using two-photon absorptio

105 Calf thymus DNA was incubated with BaP and irradiated wi

106 he binding constant for each tetrapeptide to calf thymus DNA was obtained from the negative slope of

107 Calf thymus DNA was selected for the investigation, sinc

108 When calf thymus DNA was treated with PAH o-quinones, malondi

109 Calf thymus DNA was used as the substrate as well as sho

110 Freshly dissolved calf thymus DNA was used to test the method performance.

111 nteraction of the neutral lex dipeptide with calf thymus DNA, we have prepared stable, nonmethylating

112 ) induced significant numbers of AP sites in calf thymus DNA, which were predominantly cleaved 5' to

113 Incubation of calf-thymus DNA with MA and DTT or mercaptoethanol (MER)

114 n precipitating and resolubilizing sonicated calf thymus DNA, with N4-methyl substitution of spermidi