ライフサイエンスコーパス: calibrant

1 application, because of its dependence on a calibrant.

2 ans of ratio counting using a colloidal gold calibrant.

3 nds, that is, the compound of interest and a calibrant.

4 was due to loss of HIV DNA from the 8E5 cell calibrant.

5 sed as suitable for value assigning such DNA calibrants.

6 108% for all cereals matrices using external calibrants.

7 of labeled metabolites using a mixture of RT calibrants.

8 sociated with pRSETMON-02 as opposed to gDNA calibrants.

9 ix, indicating no need to use matrix-matched calibrants.

10 tter alternative to conventional seed powder calibrants.

11 eptides to the isotopically labeled internal calibrants.

12 the detected species that serve as effective calibrants.

13 minal residues and provide valuable internal calibrants.

14 accuracy MS and MS/MS spectra using separate calibrant and analyte regions on the target plate, avoid

15 ismatching while the same molecular class of calibrant and analyte was maintained yielded larger erro

16 ass standard without the necessity of mixing calibrant and analyte.

17 fication of the 50 compounds using a generic calibrant and mass calibration achieved an average error

18 N(2)) and Omega(He) values for the drug-like calibrants and two diastereomers were measured using a d

19 ccurate calibration with a minimal number of calibrants, and the ability to extract unknown parameter

20 These calibrants are often internal and behave in a fashion si

21 Current calibrants are sometimes not designed to satisfy these r

22 Such calibrants are suitable to determine the reduced mobilit

23 In this paper, we introduce a new IM calibrant (CCS and K0) using singly charged sodium adduc

24 ification of target concentration in primary calibrant certified reference materials (CRMs), both lam

25 age of the methods presented here is that no calibrant compounds need to be added to the mobile phase

26 ure component relative to "internal affinity calibrants", compounds of known affinity for the target.

27 area and plotting the area ratio against the calibrant concentrations.

28 Since all calibrants consist of the same species and differ only i

29 obtain sufficiently high number of internal calibrants covering the entire ranges of mass-to-charge

30 sing an internal standard curve and need for calibrant diluent, and takes into account the individual

31 100-500 nmol/mol, with NO and NO2 reactants/calibrants diluted down from standards with nominal mole

32 urthermore, high method recoveries indicated calibrants do not need to undergo clean-up to account fo

33 pDNA calibrants exhibited better performance characteristic i

34 ce liquid chromatography, is also a suitable calibrant for CCS estimations.

35 his work establishes a new type of inorganic calibrant for IM-MS allowing sizing, structural analysis

36 However, currently available calibrants for CCS measurement using TWIM are predominan

37 es multiple ion isolations of an analyte and calibrants for internal calibration at each stage in a M

38 tudy of large biomolecules, however reliable calibrants for large anions have not been available.

39 cy and reproducibility of PCs and PEs as CCS calibrants for phospholipids against different classes o

40 injection and trapping of the internal mass calibrant (i.e., poly(ethylene glycol) with a 1000 Da av

41 rge effects is to introduce an internal mass calibrant (IMC) using a dual electrospray ionization (ES

42 ose of the healthy hemisphere as an internal calibrant in addition to routinely used external standar

43 show that dextran, already widely used as a calibrant in high performance liquid chromatography, is

44 nriched metalloprotein standard for use as a calibrant in species-specific isotope dilution analysis

45 l(2)O(3)) has been widely used as a pressure calibrant in static high-pressure experiments and as a w

46 r phospholipids against different classes of calibrants, including polyalanine (PolyAla), tetraalkyla

47 ins some question regarding how selection of calibrants influences TWIMS CCS measurements.

48 n "unknown" concentration without the use of calibrants, internal standards, or a calibration curve.

49 r analyte quantitation that does not rely on calibrants, internal standards, or calibration curves bu

50 ffects that would result from the spiking of calibrants into the sample.

51 This report presents a study of calibrant ion influence on CCS determination via TWIMS.

52 through the use of an internal energy-input calibrant ion that ensured reproducible energy depositio

53 Furthermore, we investigate the number of calibrant ions as well as their required m/z range in or

54 In addition, calibrant ions desorbed from a separate sample spot can

55 a method for the controlled introduction of calibrant ions in highly accurate mass measurements usin

56 well-defined series of positive and negative calibrant ions using either electrospray ionization (ESI

57 ignals using sucrose and ammonium sulfate as calibrants is presented.

58 The experimental results showed that the one-calibrant kinetic calibration technique can be used for

59 In open bed form, a one-calibrant kinetic calibration technique was accomplished

60 We demonstrate that structurally mismatched calibrants lead to larger errors in calibrated CCS value

61 The calibrant-loaded approach can provide both total and fre

62 se and analyte uptake between the sample and calibrant-loaded extraction phase, CL-EP, with a finite-

63 ICP-OES analysis for production of accurate calibrants may increase quantitative accuracy and give g

64 sue sections by MALDI t-wave IM-MS using CCS calibrants measured by MALDI drift cell IM-MS.

65 Mismatching of both calibrant molecular class and charge state resulted in t

66 tandardization of seminal plasma derived PSA calibrant molecular form mass concentrations and purific

67 centroided m/z values of the known, internal calibrant molecular ions versus that calculated from the

68 This is of particular concern when calibrants of the same molecular class (e.g., carbohydra

69 accomplished by loading benzophenone3-d5 as calibrant on the C18 coating to quantify all nonpolar co

70 lysis is achieved using ICA by incorporating calibrants on a separate spot from the sample of interes

71 rom 0.04-2.5microg/mL and stable derivatized calibrants over 7days.

72 ed CCS values while the structurally matched calibrants, PCs and PEs, gave highly accurate and reprod

73 ose are quite unreliable, leading to missing calibrant peaks in spectra and correspondingly lower mas

74 With the set of calibrants presented here, the m/z range of 40-400 kDa i

75 t to be unsuitable for the purpose of single-calibrant quantification.

76 alculated based on the fact that 100% of the calibrant reaches the plasma through the MDG, whereas fo

77 We present the kinetics of calibrant release and analyte uptake between the sample

78 4 which demonstrate their use as a TW-IM-MS calibrant set to facilitate characterization of very lar

79 Calibrant solutions are delivered from reservoirs fabric

80 ons was established and was used to identify calibrant solutions that can be employed for the simulta

81 th this system, we have been able to deliver calibrant solutions, washing buffers, or "test" solution

82 The use of internal calibrants (the so-called lock mass approach) provides m

83 a universally applicable and robust internal calibrant, the tripeptide Asn3.

84 Using the lipid calibrants, the majority of the CCS values of several cl

85 o be used with a single external nitrogenous calibrant to quantify nitrogen-containing compounds of k

86 TW IM-MS) instrumentation rely on the use of calibrants to convert the arrival times of ions to colli

87 These instruments often rely on drift-time calibrants to perform qualitative identification.

88 The PSA calibrants used to create calibration curves in these as

89 nation of small molecule and polypeptide CCS calibrants, we successfully determined the nitrogen CCS

90 e been corrected through the use of internal calibrants (well-characterized standards introduced with

91 Standard curves of the spiked calibrants were generated with concentrations ranging fr

92 Calibrants were made of nitrocellulose membranes doped w

93 Matrix-matched calibrants were needed to compensate for over recovery o

94 The development of phospholipid CCS calibrants will enable high-accuracy structural studies

95 -tagged peptides can further act as internal calibrants with high confidence in a PMM to identify the

96 -to-charge ratios and abundances of internal calibrants without a need for theoretical description of

97 standard oxidation-reduction potential (ORP) calibrants, ZoBell's and Light's solution.