ライフサイエンスコーパス: calicivirus

1 rain is one of only a few culturable enteric caliciviruses.

2 larly between those of noroviruses and other caliciviruses.

3 with those of known human and animal enteric caliciviruses.

4 /Mc114 contained features common among other caliciviruses.

5 enetically similar to the Sapporo-like human caliciviruses.

6 structure and gene expression in the enteric caliciviruses.

7 based upon establishing risks of exposure to caliciviruses.

8 ticles that have revolutionized the study of caliciviruses.

9 ossible rescue of uncultivable human enteric caliciviruses.

10 rain is one of only a few culturable enteric caliciviruses.

11 cycle of sapoviruses and the related enteric caliciviruses.

12 r future functional studies of MNV and other caliciviruses.

13 unctions and facilitates strain diversity in caliciviruses.

14 the start site of the subgenomic RNA in all caliciviruses.

15 relationship between sapoviruses and animal caliciviruses.

16 Our data indicate that the calicivirus 3CL(pro), like PV 3C(pro), mediates the clea

17 has been previously demonstrated for feline calicivirus, a member of the Vesivirus genus, PSaV trans

18 on cruise ships, 12 (86%) were attributed to caliciviruses; among these 12, outbreak characteristics

19 main is remotely related to the P1 domain in calicivirus and hepatitis E virus, suggesting a possible

20 Previous studies on feline calicivirus and murine norovirus 1 (MNV1) demonstrated t

21 We have shown for feline calicivirus and rabbit hemorrhagic disease virus that th

22 lication were derived from studies of feline calicivirus and rabbit hemorrhagic disease virus, which

23 r divided into the following species: Feline calicivirus and Vesicular exanthema of swine virus (genu

24 me sequences are now available for 5 enteric caliciviruses and demonstrate that human and animal ente

25 Motif 1 is conserved among caliciviruses and is complementary to a sequence in the

26 sequence variation among Norwalk-like human caliciviruses and is likely to contain the determinants

27 antigenic diversity and host specificity in caliciviruses and provide a structural framework for vac

28 ectious agents (Hepatitis B Virus and Walrus Calicivirus) and demonstrated that it has higher efficie

29 supercluster, which includes picornaviruses, caliciviruses, and coronaviruses.

30 roviruses, Group A rotaviruses, Sapporo-like caliciviruses, and enteric bacteria (i.e., Salmonella, C

31 nd parasitic pathogens; serum was tested for calicivirus antibodies.

32 In humans, caliciviruses are a major cause of acute gastroenteritis

33 Host immune responses to human caliciviruses are difficult to study because of the lack

34 Caliciviruses are disseminated by the fecal-oral route a

35 Caliciviruses are known to use a novel mechanism of prot

36 The positive-strand RNA genomes of caliciviruses are not capped, but are instead covalently

37 nd demonstrate that human and animal enteric caliciviruses are phylogenetically closely related.

38 Caliciviruses are single-stranded RNA viruses that cause

39 Human caliciviruses are the major cause of outbreaks of acute

40 a and also confirmed the importance of human caliciviruses as the leading cause of foodborne disease

41 ar basis of replication and pathogenesis for caliciviruses associated with diarrheal disease.

42 ncing our appreciation of the full burden of calicivirus-associated diarrhea, and it is opening new a

43 Bovine enteric caliciviruses (BEC) are associated with diarrhea in youn

44 ogenesis of two host-specific bovine enteric caliciviruses (BEC), the GIII.2 norovirus (NoV) strain C

45 Two genetically distinct bovine enteric caliciviruses (BECs) have been identified: the norovirus

46 e genogroups and genotypes of bovine enteric caliciviruses (BECVs) circulating in calves, we determin

47 canonical start/stop site in huNV and feline calicivirus but not in rabbit hemorrhagic disease virus.

48 calf fecal samples were assayed for enteric caliciviruses by using six RT-PCR primer sets designed f

49 ralizing B-cell epitope, derived from feline calicivirus capsid protein, and a well characterized B-c

50 The first x-ray structure of a calicivirus capsid, which consists of 180 copies of a si

51 nonbacterial gastroenteritis, whereas animal caliciviruses cause various host-dependent illnesses wit

52 However, all caliciviruses contained 3' terminal hairpins, and stem-l

53 ion Agency (EPA) is interested in preventing calicivirus contamination in treated waters used for con

54 ted with other feline RNA viruses, including calicivirus, coronavirus, herpesvirus, and feline leukem

55 y, we report the characterization of a novel calicivirus (CV), the Tulane virus (TV), which was isola

56 ization of Tulane virus (TV), a novel rhesus calicivirus (CV).

57 r set was found to be the most sensitive for calicivirus detection.

58 st time an NTPase activity associated with a calicivirus-encoded protein.

59 None of the enteric caliciviruses except Po/Sapo/GIII/Cowden/80/US replicate

60 the prototype of the Recovirus genus in the calicivirus family, was isolated from the stools of rhes

61 rains, MD145-12 (genus Norovirus) and feline calicivirus (FCV) (genus Vesivirus), to investigate pote

62 Feline calicivirus (FCV) and murine norovirus (MNV) are used as

63 n structures of the VPg proteins from feline calicivirus (FCV) and murine norovirus (MNV), which have

64 d at the 3' end of the genomic RNA of feline calicivirus (FCV) encodes a small (12.2-kDa) minor struc

65 ach is demonstrated by the capture of feline calicivirus (FCV) from cell culture media that is expose

66 Open reading frame 2 (ORF2) of the feline calicivirus (FCV) genome encodes a capsid precursor that

67 we show how longitudinal analysis of feline calicivirus (FCV) infection in an animal rescue shelter

68 Here, we examined the effect of feline calicivirus (FCV) infection on SG accumulation.

69 The genome of feline calicivirus (FCV) is an approximately 7.7-kb single-stra

70 Feline calicivirus (FCV) nonstructural proteins are translated

71 Expression of the region of the feline calicivirus (FCV) ORF1 encoded by nucleotides 3233 to 40

72 as to identify the active form of the feline calicivirus (FCV) RNA-dependent RNA polymerase (RdRP).

73 Feline calicivirus (FCV) strains can show significant antigenic

74 engineered in which the LC region of feline calicivirus (FCV) was placed under the control of the cy

75 Feline calicivirus (FCV), a member of the Caliciviridae, produc

76 Feline calicivirus (FCV), a member of the Vesivirus genus, prov

77 itopes in the major capsid protein of feline calicivirus (FCV), an expression library containing rand

78 or feline herpesvirus type 1 (FHV-1), feline calicivirus (FCV), Mycoplasma felis, Chlamydophila felis

79 infectious acute gastroenteritis and feline calicivirus (FCV), which causes respiratory illness and

80 regenerating system was isolated from feline calicivirus (FCV)-infected cells.

81 achment and infectious viral entry of feline calicivirus (FCV).

82 (fJAM-A) is a functional receptor for feline calicivirus (FCV).

83 We have examined the entry process of feline calicivirus (FCV).

84 s of feline coronaviruses (FCoVs) and feline caliciviruses (FCVs), respectively, and are important in

85 The capsid protein (VP1) of all caliciviruses forms an icosahedral particle with two pri

86 e we report the atomic structure of a native calicivirus from the Vesivirus genus that exhibits a bro

87 nsure that treatments are adequate to remove caliciviruses from source waters.

88 VP1 protein, including strains from all four calicivirus genera, showed the closest grouping of NB vi

89 Caliciviruses genetically related to the NLV-BEC Jena an

90 in could be provided in trans to replicating calicivirus genomes bearing a reporter gene.

91 and lagoviruses but may also represent a new calicivirus genus.

92 Caliciviruses, grouped into four genera, are important h

93 daviruses and members of the tombusvirus and calicivirus groups provide significant new data for unde

94 We propose a mechanism for enteric calicivirus growth dependent on bile acids, ubiquitous m

95 ecular techniques to the characterization of caliciviruses has resulted in an extensive database of s

96 The human enteric caliciviruses have been assigned to 2 of these genera.

97 Since then, Norwalk-like caliciviruses have been recognized to be the most common

98 or G3BP1 integrity, suggesting that related caliciviruses have distinct effects on the stress respon

99 Previous studies on caliciviruses have identified mechanisms by which they c

100 second outbreak showed that they were human calicivirus (HuCV) genogroup 1 viruses related, but not

101 powerful approach to the diagnosis of human calicivirus (HuCV) infections.

102 Human caliciviruses (HuCVs) are the major cause of outbreaks o

103 To define the role of human caliciviruses (HuCVs) in severe childhood gastroenteriti

104 of similar assays for the detection of human caliciviruses (HuCVs).

105 our study provides the first insight on how caliciviruses impair stress granule assembly by targetin

106 were essential for growth of porcine enteric calicivirus in cell culture in association with down-reg

107 walk virus (NV), a reference strain of human calicivirus in the Norovirus genus of the family Caliciv

108 uent coinfection of HAstV with rotavirus and caliciviruses in childhood diarrhea complicates the epid

109 Although laboratory confirmation of caliciviruses in stool samples was not attempted in most

110 Enteric caliciviruses in the genera Norovirus and Sapovirus are

111 unologic functions and pathogenesis of human caliciviruses in the Norovirus and Sapovirus genera is h

112 From such studies, it was proposed that caliciviruses induce apoptosis to facilitate the dissemi

113 f Health has allowed for the confirmation of calicivirus infection among patients involved in epidemi

114 nfectious peritonitis and virulent, systemic calicivirus infection are caused by certain types of fel

115 The control of outbreaks of calicivirus infection in high-density, high-throughput p

116 volution of our understanding of immunity to calicivirus infection, using Norwalk virus as the protot

117 assays and dissecting the immune response to calicivirus infection.

118 Feline calicivirus is a major causative agent of respiratory di

119 identity of the complete NB VP-1 with other caliciviruses is low, varying between 14.6 and 26.7%.

120 Norwalk virus (NV), the prototype human calicivirus, is the leading cause of nonbacterial acute

121 Norwalk virus, a noncultivatable human calicivirus, is the major cause of epidemic gastroenteri

122 that VP2, a protein apparently unique to the caliciviruses, is essential for productive replication t

123 thus far, suggesting that the VPg protein of caliciviruses, like those of picornaviruses and potyviru

124 ith cytoplasmic membrane vesicles containing calicivirus-like particles of 25 to 40 nm in diameter.

125 The calicivirus minor capsid protein VP2 is expressed via te

126 The conserved calicivirus motifs were identified in the nonstructural

127 occurs efficiently on subgenomic bicistronic calicivirus mRNAs, enabling synthesis of minor capsid pr

128 is process in vitro on two model bicistronic calicivirus mRNAs.

129 Among caliciviruses, NB virus shows amino acid identities of 1

130 Norwalk-like caliciviruses (Noroviruses) cause over 90% of nonbacteri

131 All cleavages by calicivirus or PV proteases separated the C-terminal dom

132 Eleven of the 12 calicivirus outbreaks were attributed to noroviruses, 7

133 herein make TV a valuable model for studying calicivirus pathogenesis and replication.

134 Porcine enteric calicivirus (PEC) causes diarrhea and intestinal lesions

135 Porcine enteric calicivirus (PEC) is associated with diarrhea in pigs, a

136 A porcine enteric calicivirus (PEC), strain Cowden in the family Calicivir

137 A porcine enteric calicivirus (PEC), strain Cowden in the genus Sapovirus

138 Porcine enteric calicivirus (PEC/Cowden) causes diarrhea in pigs, grows

139 Among caliciviruses, PEC has the highest amino acid sequence i

140 f new molecular diagnostic methods has shown caliciviruses (previously referred to as the Norwalk fam

141 ) were subsequently screened using universal calicivirus primers, and 17 SaV strains were confirmed b

142 he RdRp activity of the norovirus and feline calicivirus Pro(-)Pol enzymes were compared and found to

143 ovides the first structural view of a native calicivirus-protein receptor complex and insights into t

144 These comparative structural studies of caliciviruses provide a functional rationale for the uni

145 ular proteins, and its function in the human calicivirus replication cycle is not known.

146 ype strain of a group of noncultivable human caliciviruses responsible for epidemic outbreaks of acut

147 is the prototype strain of a group of human caliciviruses responsible for epidemic outbreaks of acut

148 ype strain of a group of noncultivable human caliciviruses responsible for epidemic outbreaks of acut

149 may play a role in initiating translation on calicivirus RNA through unique protein-protein interacti

150 Pg may function in translation initiation on calicivirus RNA.

151 EPA can make regulatory decisions regarding caliciviruses, significant information and technology ne

152 We used two distinct calicivirus strains, MD145-12 (genus Norovirus) and feli

153 humans and map immunological function onto a calicivirus structure.

154 triking differences between MNV and previous calicivirus structures are that the protruding domain is

155 re structural similarity to SMSV4, an animal calicivirus, suggesting a closer relationship between sa

156 ion by local or state health departments for calicivirus testing.

157 press the capsid protein of Norwalk virus, a calicivirus that causes epidemic acute gastroenteritis i

158 Tulane virus (TV) is a newly reported calicivirus that was isolated from stool samples of capt

159 m is presently the only in vitro model among caliciviruses that cause gastrointestinal disease, inclu

160 ursors and products identified in studies of caliciviruses that replicate in cell culture systems.

161 is the first report of an attenuated enteric calicivirus, the induction of diarrhea, and intestinal l

162 As observed for other caliciviruses, the PSaV genome was found to be covalentl

163 nd to date it is the only cultivable enteric calicivirus (tissue culture-adapted [TC] PEC/Cowden).

164 investigate potential strategies used by the caliciviruses to inhibit cellular translation.

165 e used as a model to examine the dynamics of calicivirus transmission and evolution in such environme

166 e features of MNV suggest that at least some caliciviruses undergo a capsid maturation process akin t

167 Many viruses, including the related feline calicivirus, use terminal sialic acids (SA) as receptors

168 The precise role of the calicivirus VPg core in virus replication remains to be

169 his relative position is conserved among all calicivirus VPg proteins examined thus far, suggesting t

170 s into the novel protein-primed mechanism of calicivirus VPg-dependent translation initiation.

171 in young cats, and virulent, systemic feline calicivirus (vs-FCV) causes a highly fatal disease in ca

172 criteria for inclusion in the present study, caliciviruses were detected in 184 (81%) by reverse-tran

173 erformance for detection of RV-A, HAstV, and calicivirus, while the sensitivity for HAdV and HEV was

174 The public health impact of caliciviruses will not be fully appreciated, nor will in

175 been exploiting endemic infection of feline calicivirus within five geographically distinct househol