ライフサイエンスコーパス: calvaria

1 membranous ossification to form skull bones (calvaria).

2 eration by examining critical defects in rat calvaria.

3 Using RT-PCR, we detected DSPP mRNA in mouse calvaria.

4 c mice leads to increased apoptosis in their calvaria.

5 mary murine osteoblastic cells isolated from calvaria.

6 using primary bone cells from newborn mouse calvaria.

7 nd decreased mineralization in newborn mouse calvaria.

8 MSCs (EPC/otMSCs) were fixed to the exposed calvaria.

9 o following RANKL or LPS injections over the calvaria.

10 g, was observed in Gli3(Xt-J/Xt-J) embryonic calvaria.

11 ed that Satb2 was down-regulated in Osx-null calvaria.

12 fibers were found in the diploe of the adult calvaria.

13 ntal defect in bones, most strikingly in the calvaria.

14 surgical control consisted of the intact rat calvaria.

15 ctin/SPARC, biglycan, and type I collagen in calvaria.

16 sed to heal a critical-sized defect in mouse calvaria.

17 , were also increased in miR-433 decoy mouse calvaria.

18 l as primary osteocytes and osteoblasts from calvaria.

19 Osteoblasts were isolated from fetal rat calvaria.

20 stic cell line, UMR-106, as well as in mouse calvaria.

21 -sized defect in the rat (Rattus norvegicus) calvaria.

22 rding the filling of critical defects in rat calvaria.

23 enile (2-day-old) and adult (60-day-old) rat calvaria.

24 he CNC have complete cleft secondary palate, calvaria agenesis, and other skull defects with complete

25 in the dura mater, consequently resulting in calvaria agenesis.

26 onate inhibition of bone resorption in mouse calvaria also is blocked by mevalonate whereas clodronat

27 ole of DSPP in the normal development of the calvaria, alveolar bone, and dentin-pulp complex.

28 mRNA was greater in mutant than in wild-type calvaria and bone marrow, suggesting a compensatory mech

29 ate, but do exhibit developmental defects in calvaria and clavicles that persist through post-natal g

30 late bone growth and inflammation over mouse calvaria and in rat mandible models.

31 er 3 weeks, animals were euthanized, and the calvaria and overlying soft tissues were processed for d

32 acts as a repressor in the developing murine calvaria and that Dlx5, Runx2 type II isoform (Runx2-II)

33 ed greater BrdU incorporation than wild-type calvaria and that Osx overexpression in C2C12 mesenchyma

34 rimary mouse osteoblasts isolated from mouse calvaria and the immortalized MC3T3-E1 cell line.

35 in other mineralized tissues like long bone, calvaria, and ameloblasts.

36 formation when injected locally over murine calvaria, and enhanced trabecular bone formation when ad

37 eoblasts in organ cultures of neonatal mouse calvaria, and in vivo using a mouse model that closely r

38 dation in cultures of human osteoclasts, rat calvaria, and rat fetal long bone.

39 expressed in mouse tissues, including bone, calvaria, and the osteoblastic cell line MC3T3-E1.

40 n that bridged a critical-size defect in the calvaria as early as 2 wk after implantation.

41 nusual form of ErbB3 in the context of mouse calvaria as well as osteoblasts in vitro and the femur m

42 d immediately deep to the inner table of the calvaria, as well as along the falx and tentorium.

43 last activity, measured using a rat neonatal calvaria assay, increased in the presence of nelfinavir

44 he hypomorphic clavicles and undemineralized calvaria associated with Runx2 haploinsufficiency, where

45 pendent loss of calcium from cultured murine calvaria at porin concentrations in the range of 1 to 10

46 old increase in new woven bone formed in the calvaria at sites of previous bone resorption was observ

47 ry osteocytes isolated from wild-type murine calvaria but not in cells isolated from mice deficient i

48 lastic cells were isolated from neonatal rat calvaria by sequential collagenase digestion.

49 ls obtained in primary cultures of the lung, calvaria, cartilage, long bone, tail, and skin.

50 Injection of PTH above the calvaria caused hypercalcemia in wild-type but not PGHS-

51 Furthermore, MIP-1 delta treatment of murine calvaria caused increased bone resorption as determined

52 sponsiveness to PTH was elevated in cultured calvaria cells expressing high levels of osterix, anothe

53 -locked 1alpha,25(OH)2-lumisterol3 analog in calvaria cells were blocked by three cytoplasmic kinase

54 Collectively, murine calvaria cells, bone marrow-derived murine cell lines (+

55 had a lower bone mass both in long bone and calvaria compared with their control counterpart.

56 genetic protein 2 (rhBMP-2), in the 8-mm rat calvaria critical-size bone defect.

57 ability to induce bone formation in the rat calvaria critical-size bone defect; therefore, they may

58 1 effects on osseous regeneration in the rat calvaria critical-sized defect model.

59 Animals were sacrificed after 22 or 44 days, calvaria decalcified and stained with hematoxylin and eo

60 a PRP preparation using a critical-size rat calvaria defect model.

61 icantly enhance bone regeneration in the rat calvaria defect model.

62 screte morphological features of the Manot 1 calvaria demonstrate that this partial skull is unequivo

63 usion of sutures without adversely affecting calvaria development.

64 orphogenic protein 2, the OBs from TIEG(+/+) calvaria displayed several mineralized nodules in cultur

65 rison of HSCs and putative HSC niches in the calvaria, epiphyses, and diaphyses, at steady state or a

66 In addition, Esl-1(-/-) calvaria exhibit an elevated mature TGF-beta/pro-TGF-bet

67 ically competent bone regenerated the native calvaria form.

68 Ca 2b cells did not induce bone formation in calvaria from mice lacking the Wnt co-receptor Lrp5.

69 minid 1 (KNM-LH 1) is a Homo sapiens partial calvaria from site GvJm-22 at Lukenya Hill, Kenya, assoc

70 nofluorescent staining of bacterium-infected calvaria (i.e., skull bone) demonstrated the presence of

71 s target two rhythmically expressed genes in calvaria, Igf1 and Hif1alpha.

72 We studied sensory innervation of the calvaria in coronal and horizontal sections of whole-hea

73 rrects the abnormal femoral growth plate and calvaria in organ cultures from embryos of the Fgfr3Y367

74 CaMKII antagonists, using the newborn mouse calvaria in vivo model, cause a 50% decrease in osteobla

75 RANKL were absent in metatarsal explants or calvaria in vivo, respectively, from Mmp9(-/-) mice, dem

76 In this study, an animal model of calvaria-induced aseptic osteolysis was used to analyze

77 Anatomically, the calvaria is consistently well segmented, with frequent b

78 Data were compared with calvaria, maxilla, lumbar vertebra, femoral neck, and il

79 We show that in mouse calvaria, miR-433 displays robust circadian rhythm, peak

80 olysis in vivo were analyzed using the mouse calvaria model, in which AdLacZ was used as the control.

81 s tested in the guided bone regeneration rat calvaria model.

82 to induce bone repair in a critical-size rat calvaria model.

83 expression from 0.5 mg simvastatin in murine calvaria (N = 12).

84 age, and tendon, but is barely detectable in calvaria, notochord, or neural retina at select stages o

85 Bone resorption pits in calvaria, observed by micro-computed tomography, and ost

86 Onlay bone grafts were performed on the calvaria of 36 guinea pigs.

87 Phex gene expression was evaluated in calvaria of 6-7-week-old mice administered with trinitro

88 of osteoblasts obtained from the developing calvaria of DSPP-null mice.

89 Importantly, in calvaria of E18.5 Osx-null embryos harboring the TOPGAL

90 The discovery of a particularly small calvaria of H. erectus indicates that this taxon overlap

91 mation when injected subcutaneously over the calvaria of mice and increased cancellous bone volume wh

92 ected into the subcutaneous tissue overlying calvaria of mice lacking IL-1 receptor type I (IL-1RI(-/

93 Forty-five bone samples removed from the calvaria of nine animals were divided in groups (n = 9)

94 response following RANKL injection over the calvaria of NLRP12-deficient chimeric mice compared with

95 into the subcutaneous tissues overlying the calvaria of normal mice once daily for 6 days and then e

96 A-III cells were inoculated over the abraded calvaria of nude mice, large tumors formed with invasion

97 miRNAs that are differentially expressed in calvaria of the E18.5 Osx(-/-) embryos compared to wild

98 Last, in calvaria of transgenic mice expressing a miR-433 decoy i

99 n and OPG ligand mRNA levels were altered in calvaria of transgenic mice in a pattern that would prom

100 analyze the effect of the distance from the calvaria on bone formation.

101 rate that attenuation of Fgfr signaling in a calvaria organ culture with an Fgfr inhibitor prevents p

102 inhibits terminal mineralization in primary calvaria osteoblast cultures when added at early stages

103 ocytes in the growth plate as well as in the calvaria osteoblasts of neonatal mice.

104 Only 20% of rat calvaria osteoblasts were viable when cultured on commer

105 culturing mouse bone marrow cells with mouse calvaria osteoblasts, we found by molecular cloning and

106 ed into contralateral critical-size 6 mm rat calvaria osteotomies in 18 animals.

107 When isolated from the calvaria, Ppia(-/-) osteoblasts demonstrate decreased os

108 TNF treatment of fetal calvaria precursor cells or MC3T3-E1 clonal pre-osteobla

109 Here we describe a partial calvaria, recently discovered at Manot Cave (Western Gal

110 re, and histologic sections of the embryonic calvaria revealed that PRP leads to suture fusion.

111 Indeed, E18.5 Osx-null calvaria showed greater BrdU incorporation than wild-typ

112 independent biological assay involving mouse calvaria (skull bone) primary cell cultures, in which a

113 day 15 on the closure of the embryonic mouse calvaria sutures ex vivo was also studied.

114 Our data supported a model that within the calvaria sutures Twist1 homodimers (T/T) reside in the o

115 tosis, which is the premature closure of the calvaria sutures.

116 erived from regions of the fetal mandible or calvaria that do not undergo endochondral ossification f

117 In the adult calvaria, the highest concentration of peripherin- and C

118 cell isolation protocol employed human fetal calvaria tissue sequentially digested with trypsin and c

119 re, we show that p45-sErbB3 stimulated mouse calvaria to secrete factors that increased the invasiven

120 larly, intramembranous bone formation on the calvaria was reduced 60% in COX-2(-/-) mice following in

121 Calvaria were harvested at 12 weeks postsurgery and eval

122 ression in mouse phalangeal chondrocytes and calvaria, which suggests a role of TBC1D24 in skeletogen