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1 say and identify the samples from which they came.
2 ard a better understanding of cAMP signaling came 18 years ago with the discovery of the exchange pro
5 more revolutionary was the information that came afterward: protein dynamics play a critical role in
6 The proliferative burst after PD-1 blockade came almost exclusively from this CD8(+) T-cell subset.
8 ter kinases identified in the past 3 decades came as a surprise, as protein phosphorylation on Ser, T
9 , the main transducer of replication stress, came as a top candidate gene for camptothecin synthetic
10 immigrated as children than among those who came as adults; however, direct comparisons across Hispa
16 tion conferred by these individual mutations came at the cost of reduced mating efficiency with cells
19 We find no evidence that these improvements came at the expense of employment, sales, credit ratings
20 tive in reducing hERG binding affinity, this came at the expense of higher than desired Pgp-mediated
27 ike the case for other sampling methods that came before, there are parameters that are needed for qu
31 the PBX1, RORalpha, NTN1, and SYT6 loci also came close to genome-wide significance levels (P = 10(-6
33 recognition of the essentiality of n-3 PUFAs came decades later despite compelling evidence of their
36 first 10 s or until VF terminated, whichever came first (11.4 +/- 2.9 s to defibrillator charging).
37 (myocardial infarction or stroke, whichever came first) was lower in the surgery group (199 events a
40 an cooperation." We believe that cooperation came first, making culture and thus cultural group selec
61 dual recognition of the encapsulated anions came from (1)H NMR and UV-vis spectroscopies and ITC tit
68 ing system from 122,421,765 sentences, which came from 21,014,382 MEDLINE citations (i.e., the comple
71 diet and a nutritive property of breast milk came from 3 studies that supported the link between fish
72 1 infected MSM in Shenzhen were migrants who came from 31 of the 34 provinces of China, and these mig
75 y to the standard scheme, blue Off responses came from a blue On bipolar and inverting amacrine cell.
76 material in the northern hemisphere of Vesta came from a depth of about 20 kilometres, whereas the ex
77 ed to be independent of whether the patients came from a disadvantaged or an affluent neighborhood.
79 a (2R)-2-methyl-3-ketoacyl-ACP intermediate, came from a newly developed coupled ketosynthase (KS)-ke
80 mal medium where the only source of arginine came from a peptide 5 to 10 amino acid residues in lengt
81 trate that the Eurasian backflow into Africa came from a population closely related to Early Neolithi
84 assion for science and a broad interest that came from a strong commitment to curiosity-driven resear
87 e ruling elite controlled raw materials that came from afar whereas the intermediate elite may have b
89 The primary heterogeneity in the studies came from age and sex matching and the extent of coronar
92 We show that the previous lack of agreement came from an extended practice of using standardized mea
93 le regions, and the fact that these families came from an isolated population, we hypothesized that t
101 peroxide/substrate radical pair intermediate came from detection of enzyme-bound superoxide during tu
102 Three quarters of the GWF related to N loads came from diffuse sources (agriculture), 23% from domest
104 cells respond in an antigen-specific fashion came from experiments revealing that subpopulations of m
106 Support for barrier deficiency initiating AD came from flaky tail mice, which have a frameshift mutat
110 F and plasma sequences, indicating that they came from HIV-1 from 2 different compartments, one poten
112 se who were caries free, children with S-ECC came from households with lower income; they were more l
114 n findings was limited because most evidence came from indirect comparisons of trials with short (</=
118 port for a demethylase-independent mechanism came from mice expressing a catalytically inactive KDM6A
119 f the self-reported physical activity, 68.3% came from mild activities, 25% from moderate activities,
120 rths of energy in purchases by US households came from moderately (15.9%) and highly processed (61.0%
121 Further evidence for Eaf3/5/7 within NuA4 came from mutations in the subcomplex leading to approxi
123 spective of donor status, suboptimal kidneys came from older donors with a higher incidence of diabet
124 Sixty-five percent (68/105) of individuals came from ophthalmology departments that ranked in the t
125 cemic normoxic conditions; 51% of the energy came from oxidative phosphorylation and 49% came from gl
129 ociodemographic, dietary, and lifestyle data came from questionnaires self-completed at recruitment,
134 to honey bees providing pollination services came from residues in non-focal crop pollen, likely cont
135 ldren aged 12-23.9 mo, 9% of sodium consumed came from restaurant foods, and 4% of sodium came from c
136 egative effect of deer exclusion on Alliaria came from rosette transitions, whereas the largest posit
137 t contributions to the CHD mortality decline came from secular decreases in blood pressure and increa
139 rt for the underlying complexation chemistry came from single-crystal X-ray diffraction analyses and
143 Much of the information about discussions came from surrogates of patients who died before baselin
148 ting molecular mechanisms, the first inkling came from the behavior of cells in which this system was
151 But perhaps the paper's greatest influence came from the concept of functional architecture (the co
157 d under the expectation that these molecules came from the Endoplasmic reticulum (ER) or the plasma m
159 troscopy were performed if the microorganism came from the gastrointestinal tract in patients >/=50 y
161 with repeated examinations, 54% (n = 19 687) came from the group in which repeated EGD was not expect
162 High fluorescence intensity of HDTA in mice came from the ileum, and it was eliminated from the body
165 of care (whether the patient lived or died) came from the Intensive Care National Audit & Research C
166 lower, indicating that much of the variation came from the kinetic binding (kon) of the proteins.
168 d CLM during endocrine therapy, the majority came from the letrozole monotherapy arm (n = 318), follo
169 Data to inform each of these parameters came from the literature and from special projects condu
176 y localized, which indicates that these ORFs came from the nucleus or (less likely) a cryptic endosym
177 consistent with that number; support for 25 came from the observation that flagella can assemble and
179 elated to irregular adherence; the remainder came from the private sector, related to treatment non-c
188 of ground-state charge transfer complexation came from the UV-vis spectra and the static quenching of
191 with stable isotopes showed that Cu in seeds came from two sources: directly from roots and via remob
195 nd present case estimates for Chagas disease came from various sources, including WHO and other epide
203 in cells allowed us to analyze proteins that came in close proximity to the Gag proteins as they were
204 determined only by those lipids the channels came in contact with first after purification and can se
206 es per year), nonoperative trauma management came in second (with 20.0 [33.0] procedures per year), a
207 x structures could be unfolded enzymatically came in the late 1990s with reports that some well-known
208 ir for children younger than 6 months of age came in third (with 14.7 [13.8] procedures per year).
210 ode was deciphered, but how the genetic code came into being has not been satisfactorily addressed.
212 ew law, the Organ Transplant Act 2008, which came into effect in January 2010 and sets out principles
214 etter fit than the date when the legislation came into force (26 March 2006), suggesting an anticipat
216 Alzheimer or Parkinson's diseases, and hence came into the focus of research interest and as a therap
217 time intervals that include experiences that came just before the health event with control-time inte
218 ial demonstrations of memory reconsolidation came mainly from animal studies, evidence for reconsolid
219 otection offered by immunization with SLTRiP came mainly from T-cells, and antibodies had little role
221 5% CI, 0.1%-1.8%) developed grade 3 LVSD and came off study, and 13 (3.2%) (95% CI, 1.9%-5.4%) had si
223 etically modified soybean oil Plenish, which came on the U.S. market in 2014 and is low in linoleic a
228 However, our understanding of PRL function came primarily from studies with cultured cell lines abe
229 y rituximab and its addition to chemotherapy came the first observation that minimal residual disease
238 nd two patients with Parkinson's disease who came to autopsy 18 months and 16 years post-transplantat
239 ue of two Huntington's disease patients, who came to autopsy 9 and 12 years post-transplantation, and
240 irst 157 participants of 'The 90+ Study' who came to autopsy, including participants with dementia (n
243 es, reported in Cell Host & Microbe in 2008, came to be and contributed to our understanding of micro
245 This Retrospective on how these studies came to be is offered as a means to highlight the 25th a
246 , it remains unresolved how the bottle gourd came to be so widely distributed, and in particular how
252 asy obstacles with wide gaps for passage but came to dominate the postures used as obstacle challenge
254 After target presentation, they gradually came to encode the location of the targets and the upcom
255 l Cd and Se burdens increased over time, and came to equal those measured in indigenous C. punctipenn
256 s to optimize for CNS druglike molecules, we came to focus on the di(pyridin-2-yl)amines because of t
257 solate genes both physically and by sequence came to fruition, researchers (and patent offices) began
258 le numbers of examined lymph nodes (ELN) and came to inconsistent conclusions as to the value of the
259 In this personal perspective I relate how I came to know John as his postdoctoral fellow at the Labo
260 tion in detail and from clinical history, we came to know that he had inserted a safety pin within th
261 synovial joints first evolved as vertebrates came to land, with ray-finned fishes lacking lubricated
265 tial for manual skill in intact animals, but came to mediate this skill due to training after stroke.
268 erally altered these parameters so that they came to more closely resemble the levels found in younge
269 clades of terrestrial vertebrates, dinosaurs came to occupy an extensive morphospace throughout their
274 that normal is a derived mutant allele that came to predominate and define the leaf shape of cultiva
277 he basal ganglia and ventral temporal cortex came to represent attentional states more distinctively.
278 o left the National Institutes of Health and came to Scripps), and the gifted postdoctoral fellows wh
281 moir-diary during World War I explain how he came to the decision to stray and to stay so far from hi
282 ld man without underlying medical conditions came to the emergency department for evaluation of persi
283 further suggests that these deep waters only came to the surface under sea ice, which insulated them
284 A 62-year-old Asian male construction worker came to us with intense ocular pain, injection of the co
285 nitially learnt, but with prolonged training came to withhold responding during the trace-conditioned
286 r 2014, scientists with varying perspectives came together at Georgetown University to discuss the fo
287 ughout the workshop, the groups periodically came together in plenary sessions to reflect on other gr
288 researchers, family members, and friends who came together to memorialize his son and create knowledg
289 ceutical companies developing CDI treatments came together to seek advice from a panel of experts.
290 ere young scientists from all over the world came together to study cellular and molecular mechanisms
292 ical entity a century ago, the disorder only came under intense molecular scrutiny in the mid-1980s.
294 hydroxytyrosol and oleuropein by themselves came up as relatively weak inhibitors, despite their eff
299 andscape productivity optimization, however, came with a heavy cost of reduced environmental resilien
300 e presented a case of a 30-year-old male who came with symptoms of muscle weakness, carpopedal spasms
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