ライフサイエンスコーパス: can tolerate

1 t are much higher than non-transformed cells can tolerate.

2 evel of Bim that effector and memory T cells can tolerate.

3 ighest level of disturbance that the species can tolerate.

4 tly on how much stress the affected organism can tolerate.

5 While the wild-type strain can tolerate 10% oxygen for growth, the growth of the md

6 ental studies have shown that although axons can tolerate 100% strain under slow loading rates, even

7 resumed lactose intolerance or malabsorption can tolerate 12 to 15 g of lactose.

8 t Pol lambda has a flexible active site that can tolerate 8-oxo-dG in either the anti- or syn-conform

9 Normally, rats can tolerate a 60% fat diet because 96% of the surplus f

10 The described method can tolerate a broad spectrum of functional groups, incl

11 The structure helps explain how B4e8 can tolerate a certain degree of sequence variation with

12 Although Env can tolerate a high degree of mutation in five variable

13 sis and in vivo validation revealed that LNs can tolerate a loss of approximately 50% of their FRCs w

14 results demonstrate that the enzyme complex can tolerate a size difference between the two b subunit

15 This method can tolerate a variety of functional groups and does not

16 hange reactions proceed regioselectively and can tolerate a variety of functional groups, thus provid

17 nsitive to the emergence of such figures and can tolerate a variety of spectral and temporal perturba

18 y and that the 4-position of the phenyl ring can tolerate a wide variety of substituents.

19 The zebrafish embryo is transparent and can tolerate absence of blood flow because its oxygen is

20 ral entry activity, identifying regions that can tolerate altered structure without loss of function.

21 indicate that many adults with Down syndrome can tolerate amyloid-beta deposition without deleterious

22 xylic acid and alkyne coupling partners, and can tolerate an array of functional groups, including ca

23 han FGF22-FGFR1c2 In addition, FGF22-FGFR1c2 can tolerate an HS chain having an N-acetylglucosamine r

24 Our results showed that NDV can tolerate an IGS length of at least 365 nt.

25 se results indicate that the HAV polyprotein can tolerate an insertion at the 2A/2B junction and that

26 of treatment burden and benefit the patient can tolerate and about emotional, cognitive, spiritual,

27 asive, fast-growing grass with high biomass, can tolerate and accumulate large quantities of Pb in it

28 g regimens should be chosen that the patient can tolerate and adhere to, and the consequences of resi

29 me animals, such as Drosophila melanogaster, can tolerate anoxia for prolonged periods without appare

30 It can tolerate any nucleotide at the first three positions

31 Each can tolerate any unpaired nucleotide (A, G, C, or U) at

32 indicate that nucleocytoplasmic trafficking can tolerate both partial depletion of RanGAP and deloca

33 nd that other positions on the inositol ring can tolerate bulky substituents.

34 Our results indicate that MCM can tolerate catalytically inactive subunits and still f

35 enomic loci by a 20 nt guide sequence, which can tolerate certain mismatches to the DNA target and th

36 ly, we find that the S1 and S3 binding sites can tolerate changes that are expected to increase or de

37 exhibit significant organ proteotoxicity and can tolerate chemotherapy.

38 osomes are remarkably robust structures that can tolerate considerable changes in protein composition

39 This confirms that these fish can tolerate considerable metal accumulation, highlighti

40 equirements, the cage domain of the molecule can tolerate considerable structural modifications witho

41 e readily under experimental conditions that can tolerate considerable variation and form micrometer-

42 data with noisy incomplete samples, i.e. it can tolerate data missing from individual time points.

43 eling activity while DNA remodeling activity can tolerate defective ATP hydrolysis of alternating sub

44 ease, but only for the very few species that can tolerate deforestation.

45 main unclassified, implying that yeast cells can tolerate deletion of a substantial number of individ

46 Yeast cells can tolerate deletion of either the YPT31 or the YPT32 g

47 he maximal rate of SLR that these ecosystems can tolerate depends partly on mineral sediment depositi

48 inding proteins (found mostly in eukaryotes) can tolerate disorder.

49 ntly, cells cultured on stiff ECM substrates can tolerate disruption of multiple stress fibers with n

50 the regions of the antigen-binding site that can tolerate diversity without compromising stability.

51 equire a moderate amount of PD treatment and can tolerate dopamine agonist therapy.

52 f MNAs of the species, the proposed approach can tolerate edge loss in PPI networks and even discover

53 ur study provides evidence that some sponges can tolerate environments that appear unsuitable to many

54 evolutionary flexibility in SCR, whereby SCR can tolerate extensive amino acid changes within the lim

55 X inactivation in the extraembryonic lineage can tolerate extensive demethylation while normal levels

56 Most egg-allergic children can tolerate extensively cooked eggs.

57 protein domains under certain circumstances can tolerate extreme mutations giving rise to partial, b

58 as if their social and economic environments can tolerate false alarms, such predictions would be imp

59 eye movements (79 to 393 mN), the NFVB alone can tolerate forces of 98 mN at 0% to 10% strain and 393

60 trated that the first position of this motif can tolerate functional substitution.

61 Parasites with an intact glycolysis can tolerate genetic deletions of TgPEPCKmt as well as o

62 It can tolerate geometric variations and even permits conju

63 Most critically ill patients can tolerate hemoglobin levels as low as 7 mg/dL, so a m

64 Immunocompetent humans and animals, however, can tolerate high doses of L. monocytogenes without deve

65 Thus, cell lines and animals can tolerate high doses of these modified cytidines with

66 pt enrollment and reasonable reliability but can tolerate high measurement burden.

67 birds, indicating that resistant lymphocytes can tolerate high Myc expression.

68 quire an extended ordered lattice array, and can tolerate high noise and some missing intensity data

69 synthesis requires processing machinery that can tolerate highly variable substrates.

70 ed by 66 to 78 nucleotides and show that HAV can tolerate insertions at the N terminus of the polypro

71 njugation, highlighting regions of TraI that can tolerate insertions of a moderate size.

72 her must contain an intrinsic fluorophore or can tolerate its introduction by mutagenesis.

73 The finding that highly connected proteins can tolerate just as many amino acid substitutions as ot

74 res the presence of PS1, Pen2, and Aph1a but can tolerate knockdown of PS2 or Aph1b.

75 This highly chemoselective method can tolerate labile and reactive chemical functionalitie

76 These observations reveal that the replisome can tolerate leading-strand template lesions without dis

77 For patients who respond and can tolerate lifelong therapy, HIV infection may become

78 nd their precise three-dimensional locations can tolerate little to no overlap.

79 These results argue that cells can tolerate low levels of p180 as long as Mcm10 is pres

80 nt of fidelity and suggests that polymerases can tolerate many substitutions that alter fidelity with

81 ith the idea that the L-selectin protease(s) can tolerate minor structural alterations at the cleavag

82 The RNAi machinery can tolerate mismatches but is exquisitely sensitive to

83 ces cerevisiae, is a facultative aerobe that can tolerate mitochondrial mutations that would be letha

84 t the linker regions between the two modules can tolerate moderate structural changes and that the bu

85 the hypothesis that the adult primate brain can tolerate moderately reduced levels of wild-type Hunt

86 nd those of others suggest that although DNA can tolerate modifications with RNA-like (North) nucleot

87 HIV-infected individuals can tolerate more intensive chemotherapy, as they have b

88 at a lower efficiency, indicating that CPAF can tolerate more mutations inside Chlamydia-infected ce

89 to Alzheimer's disease, whereby some people can tolerate more of these changes than others and maint

90 evolutionary routes to generalism: organisms can tolerate multiple environments or they can modify th

91 to minimize solid deposition, the technique can tolerate Na matrix up to 10000 ppm (1%) with only ap

92 technologies involve polymeric materials and can tolerate neither the high-temperature nor the high-p

93 al identification is highly reproducible and can tolerate numerous variables, including differences i

94 Not all patients with rheumatoid arthritis can tolerate or respond to methotrexate, a standard trea

95 assays of mutants show that the apical loop can tolerate perturbation in length and surface residues

96 aken together, our model suggests that cells can tolerate perturbations to localization phenotypes, w

97 These results reveal that cells can tolerate protein waste, but not the amino acid scarc

98 demonstrating that the RealTime HIV-1 assay can tolerate raltegravir-selected mutations.

99 We demonstrate that M-Probes can tolerate sequence variations of up to 7 nt at prescr

100 lencing and activating functions of the m-AH can tolerate significant changes in length and sequence.

101 t the calculations predict that the membrane can tolerate significant differences in the resting area

102 We find that VH-B1a can tolerate significant diversity within all three comp

103 the morphological event and also that cells can tolerate significant levels of unphosphorylated SpoI

104 to the 3' end of transcripts for detection, can tolerate significant RNA degradation, while still yi

105 leotides found at the 5' mRNA start sequence can tolerate significant sequence variability without af

106 A degradation channel that can tolerate some steric bulk may reconcile the two oppo

107 strate that tetramolecular i-motif structure can tolerate specific flanking G-repeats.

108 ing studies have shown that some individuals can tolerate substantial amounts of Alzheimer's patholog

109 indicating that the DNA of replicating cells can tolerate substantial substitution with ClU.

110 ndicate that the ring N3 of 6-anilinouracils can tolerate substituents of considerable size and struc

111 emic injury, thereby extending the time they can tolerate such an insult.

112 Robust beta-hairpins that can tolerate such changes are attractive tools for study

113 single nucleotide polymorphism analyses that can tolerate such imperfections in archived tissues.

114 ion (HSCT), at least in younger patients who can tolerate such intensive treatments.

115 deficiency is cell lethal, but the intestine can tolerate such lethality at the organ level.

116 For example, ground squirrels and camels can tolerate temperatures more than 40 degrees C better

117 s, we identify mutants of P. aeruginosa that can tolerate the depletion of MvaT in an DeltamvaU mutan

118 rapy for patients with chronic-phase CML who can tolerate the drug.

119 ng why most individuals carrying this allele can tolerate the drug.

120 jacketed capillary columns were used as they can tolerate the elevated pressures required.

121 roductivity; at low productivity few species can tolerate the environmental stresses, and at high pro

122 vely, these data suggest that polymerase eta can tolerate the geometric distortions in DNA conferred

123 addition, we have demonstrated that the PRR can tolerate the insertion of a peptide-binding domain,

124 (i) SIN nsP3 can tolerate the insertion of GFP into different fragmen

125 oduce the replicative form of the Pf4 genome can tolerate the loss of both MvaT and MvaU.

126 rganisms, the yeast Saccharomyces cerevisiae can tolerate the loss of mitochondrial DNA (mtDNA).

127 The assay is stable over a 24-h period and can tolerate the presence of dimethyl sulfoxide up to 8%

128 The selectivity of this surface reaction can tolerate the presence of internal cysteines in close

129 Cyanobacterium Nostoc commune can tolerate the simultaneous stresses of desiccation, U

130 sites selects for antibody sublineages that can tolerate these changes, thereby providing a mechanis

131 unction, whereas the amino terminus of VP19C can tolerate transposon insertions.

132 nd shows that if liver transplant recipients can tolerate treatment for 1 year there is a reasonable

133 o be able to predict critical positions that can tolerate two different amino acids and retain functi

134 In addition, we found that CSOD can tolerate up to 3.9% dimethyl sulfoxide (DMSO) and up

135 These observations indicate that ATF3 can tolerate variations in the center of the binding sit

136 The Co(II)-catalyzed process can tolerate various substitution patterns and produces

137 promiscuous donor substrate specificity and can tolerate various substitutions at C-5 or C-9 of the

138 mine the mutational burden that active sites can tolerate, we randomly mutated a stretch of 13 amino

139 domain to the cytoplasmic membrane and thus can tolerate wide divergence and multiple insertions and

140 ell as the degree of modifications the sgRNA can tolerate without compromising its association with S