ライフサイエンスコーパス: canine

1 weapon morphology (e.g., antlers, horns, and canines).

2 lar remodeling in the chronic phase of MI in canines.

3 DN completely normalizes hepatic SI in obese canines.

4 t a coupling interval of 200 ms in 7 healthy canines.

5 LLTS) suppresses atrial fibrillation (AF) in canines.

6 the mandible than maxilla, it affects mostly canines.

7 dge to better understand, train, and utilize canines.

8 Canine AD is a pruritic inflammatory condition that show

9 Acute canine AD skin lesions had a significant up-regulation o

10 antagonist in an allergen challenge model of canine AD, both clinically and histologically, to invest

11 469 (64.4%) red foxes were seropositive for canine adenovirus (CAV) by ELISA.

12 Canine adenovirus type 1 (CAV-1) causes infectious canin

13 The role of canine adenovirus type 2 (CAV-2), primarily a respirator

14 sing a retrograde Cre-recombinase-expressing canine adenovirus-2 in combination with Cre-dependent in

15 d structural study of representative bat and canine adenoviruses to better understand the relationshi

16 on of complete wet (n = 97) and dry (n = 80) canine and feline pet food sold in the UK was measured t

17 issue excitation model in 2-dimensional (2D) canine and human and 3D canine biventricular models.

18 ty of HL18NL11 or HL17NL10 viruses to infect canine and human cells might reflect a zoonotic potentia

19 es the feasibility of seizure forecasting in canine and human epilepsy.media-1vid110.1093/brain/aww04

20 rvations evidence a great similarity between canine and human V-SVZ indicating that the dog may be be

21 Renal complications are sequelae of canine and human visceral leishmaniasis (VL).

22 ion defects, oral sites other than maxillary canine and premolar teeth, and Miller Class III and IV d

23 Twenty-one canines and 24 patients with acute MI were studied.

24 The close evolutionary relationship between canines and humans may have spawned a unique bond in reg

25 ing intracranial electroencephalography from canines and humans with epilepsy.

26 nt on noncontacting surfaces of incisors and canines and nonfunctional cusps of posterior teeth.

27 ith MI by in vivo delayed-enhancement MRI in canines and patients.

28 mages of the AAR and MI by histopathology in canines and with MI by in vivo delayed-enhancement MRI i

29 ipients have been developed in mouse, swine, canine, and nonhuman primate models.

30 he contacting surfaces of incisors, cusps of canines, and functional cusps of posterior teeth.

31 knowledge of the odors cuing the canine, but canines are easily exposed to unintentional explosive od

32 precise visualization of the transmigrating canine as well as ruled out resorption of roots of mandi

33 Canine atopic dermatitis (CAD) is a chronic inflammatory

34 kin microbiome, and highlight the utility of canine atopic dermatitis as a spontaneous nonrodent mode

35 ylococcus species, concurrent with decreased canine atopic dermatitis severity.

36 In a cohort of 14 dogs with canine atopic dermatitis, the skin microbiota were longi

37 itis, this study used a spontaneous model of canine atopic dermatitis.

38 detailed biophysical models of the entire 3D canine atria was developed.

39 H3N8 viruses from different origins (equine, canine, avian, and seal) were performed.

40 he acquired genetic alterations that lead to canine B-cell lymphomas (cBCLs).

41 A standardized questionnaire, the Canine Behavioral Assessment and Research Questionnaire

42 In normal canines, bipolar electrodes were chronically implanted o

43 n 2-dimensional (2D) canine and human and 3D canine biventricular models.

44 nis PCR-positives were identified from 6,844 canine blood samples from 22 U.S. states, resulting in 2

45 or or HMS) was tested on four human and four canine bone marrow aspirates.

46 .01) among strains of M. canis isolated from canine brain tissue or mucosal surfaces.

47 roup of symptoms related to the aging of the canine brain.

48 With canine brains, we performed extensive analysis of pathol

49 for actual knowledge of the odors cuing the canine, but canines are easily exposed to unintentional

50 ion and drug sensitivity data from human and canine cancer cell lines, and canine OS tumor datasets.

51 Canine cancers represent a tremendous natural resource d

52 e focused on three distinct human-comparable canine cancers representing different tissues and embryo

53 alterations, we explored their relevance in canine cancers.

54 Normal canine cardiac anatomy is responsible for %dLV and %dT v

55 The H3N8 LACIV replicates efficiently in canine cells at 33 degrees C but is impaired at temperat

56 ed samples generated from Ehrlichia-infected canine cells covers 93% of the Ehrlichia genome, suggest

57 Here, we show that dividing human and canine cells partition transfected plasmid DNA asymmetri

58 allowed efficient entry into both feline and canine cells without successful infection.

59 to block general gene expression in human or canine cells.

60 s E186 and blocks general gene expression in canine cells.

61 e, we resolved a quantitative trait locus on canine chromosome 1 to a 188-kb critical interval that e

62 The analysis revealed a modifier locus on canine chromosome 25.

63 We previously identified a ~1.5 Mb locus on canine chromosome 27 associated with CAD in German sheph

64 ty index for anterior crowding; 2) molar and canine class relationship; 3) previous orthodontic treat

65 corners of the mandible (two angles and two canines): class I (lateral), class II (hemimandibulectom

66 Canine cognitive impairment syndrome (CDS) represents a

67 l to absent in an extended RPGRIP1 (ins/ins) canine colony, irrespective of the MAP9 genotype.

68 ctin-binding proteins SpsD and SpsL from the canine commensal and pathogen Staphylococcus pseudinterm

69 osed design will enable efficient mapping of canine complex diseases, most of which have human homolo

70 A form of canine cone-rod dystrophy (cord1) was originally associa

71 Next, canine corneas were inoculated with CHV-1 for 48 h, and

72 bjects, with an increase in sharpness of the canine coronary arteries of 85% +/- 72%.

73 Canine deaths have resulted from the consumption of indo

74 Canine degenerative myelopathy (DM) is a naturally occur

75 Integrating local estimates for canine demography and costs, we predicted the impact of

76 histological validation studies performed in canines demonstrated that HIC regions in balanced steady

77 ies are warranted to evaluate the utility of canine diabetes to provide novel mechanistic insights to

78 Herein, we consider the potential for canine diabetes to provide valuable insights for human t

79 ge voids exist regarding the pathogenesis of canine diabetes.

80 The canine disease is a non-syndromic LCA-ciliopathy, with n

81 ilar to human type 1 diabetes, the canonical canine disorder appears to be increasing in prevalence.

82 s that have been recently vaccinated against canine distemper virus (CDV) and develop respiratory dis

83 Both canine distemper virus (CDV) and rabies virus (RABV) cau

84 iridae such as PIV3, Sendai virus (SeV), and canine distemper virus (CDV) are resistant.

85 gous CDV strains.IMPORTANCE Rabies virus and canine distemper virus (CDV) cause high mortality rates

86 We report an outbreak of canine distemper virus (CDV) infection among endangered

87 een controlled successfully, others, such as canine distemper virus (CDV), are a growing concern.

88 gain insight into the methylation changes of canine DLBCL, we investigated the DNA methylome in prima

89 Serial carbon isotope ratios (delta(13)C) in canine enamel from individuals that lived between 1960-2

90 we have examined the potential of H3N8 from canine, equine, avian, and seal origin to productively i

91 It has a lethal canine equivalent: necrotizing meningoencephalitis.

92 titative trait loci that are responsible for canine facial shapes and sizes.

93 l source tracking (MST) for human, gull, and canine fecal sources, monitoring of enterococci and feca

94 om 70 species, including non-human primates, canines, felines, equids, ovids, suids, bovins, salmonid

95 viral (AAV) serotype 8 vector delivery of a canine FVII (cFVII) zymogen transgene.

96 uNoV virus-like particles (VLPs) can bind to canine gastrointestinal tissue, suggesting that infectio

97 al and electroencephalographic features of a canine generalized myoclonic epilepsy with photosensitiv

98 LUPA consortium to substantially expand the canine genome annotation to include 10 374 novel lncRNAs

99 Here we undertake the largest canine genome-wide association study to date, with a pan

100 We created the largest existing catalog of canine genome-wide variation and compared it against two

101 d on the recently released annotation of the canine genome: the exome-plus design and the exome-CDS d

102 , we assembled and analyzed a data set of 34 canine genomes.

103 isease using the murine (twitcher mouse) and canine [globoid cell leukodystrophy (GLD) dog] models.

104 Canine HACD1 deficiency is histopathologically classifie

105 ta-RII-DN) in the posterior left atrium in a canine heart failure model will sufficiently attenuate f

106 lated chick cardiomyocytes and sections from canine heart, we revealed by ground-state depletion and

107 that donation after circulatory death (DCD) canine hearts can be resuscitated if perfused with warm

108 the mathematical model, in coronary-perfused canine hearts, the addition of dofetilide (selective IKr

109 adenovirus type 1 (CAV-1) causes infectious canine hepatitis (ICH), a frequently fatal disease which

110 s to indospicine is consistent with observed canine hepatotoxicity, and considering the higher in vit

111 oline receptors was upregulated in human and canine HF compared with nonfailing controls.

112 critical pathological component of human and canine HF.

113 e performed whole exome sequencing (WES) and canine high-density (cHD) SNP genotyping of 28 dogs from

114 nd volumes and suppressed LA fibrosis in the canine high-rate ventricular pacing model.

115 moderate risk to public health and that the canine host should be monitored for emerging IAVs.IMPORT

116 Experimental acute canine house dust mite-induced AD lesions exhibit an act

117 tudy of the 14 histidine residues present in canine HSP47, where we have mutated all histidine residu

118 ty alongside associations with MHC and other canine immune response genes parallel that of different

119 Canine influenza is a respiratory disease of dogs caused

120 n of avian-origin IAVs in mammals.IMPORTANCE Canine influenza is a respiratory disease of dogs caused

121 The A/H3N8 canine influenza virus (CIV) emerged from A/H3N8 equine

122 pes of influenza A virus (IAV), avian-origin canine influenza virus (CIV) H3N2 (CIV-H3N2) and equine-

123 An avian-origin canine influenza virus (CIV) has recently emerged in dog

124 A new H3N2 canine influenza virus (CIV) of avian origin emerged in

125 A single subtype of canine influenza virus (CIV), A(H3N8), was circulating i

126 a is a respiratory disease of dogs caused by canine influenza virus (CIV).

127 n reported in dogs in the last 16 years: the canine influenza viruses (CIV) H3N8 and H3N2 of equine a

128 mergence, summarize our knowledge of the new canine influenza viruses (CIVs) and how they provide key

129 Canine influenza viruses (CIVs) are the causative agents

130 ological characterization of H3N8 equine and canine influenza viruses using various experimental appr

131 a viruses (CIVs) are the causative agents of canine influenza, a contagious respiratory disease in do

132 Canine insulin deficiency diabetes is, in some cases, co

133 fectiveness threshold above $1,400 per DALY, canine interventions are at least 95% likely to be optim

134 This case study of cost-effective canine interventions in Tamil Nadu may have applicabilit

135 moprevention for the explicit benefit of the canine is compelling since dogs are an important part of

136 ion and is required to stimulate Madin-Darby canine kidney (MDCK) cell scatter.

137 an expanding island of confluent Madin-Darby canine kidney (MDCK) cells as a model system to quantify

138 the establishment of polarity in Madin-Darby canine kidney (MDCK) cells in part through phosphorylati

139 Madin-Darby canine kidney (MDCK) cells stably transfected with human

140 rface localization, we generated Madin-Darby canine kidney (MDCK) cells that stably express EGFP-EAAT

141 solateral membranes of polarized Madin-Darby canine kidney (MDCK) cells, but enzyme activity was seve

142 show similar growth kinetics in Madin-Darby canine kidney (MDCK) cells, but pH1N1low-1 is significan

143 easing concentrations of HGF, in Madin-Darby canine kidney (MDCK) cells, grown as cysts in 3D collage

144 ells and larger sheets of motile Madin-Darby canine kidney (MDCK) cells.

145 e and tricellulin overexpression Madin-Darby Canine Kidney (strain II, MDCKII) cells.

146 In Madin-Darby canine kidney cell cultures overlaid with human or swine

147 tubulogenesis in Tuba knockdown Madin-Darby canine kidney cell cysts cultured in a collagen gel.

148 Tension across Madin-Darby canine kidney cell monolayers was increased by a low lev

149 ructures in polarized epithelial Madin-Darby canine kidney cell transfectants.

150 n together, knockdown of NCX1 in Madin-Darby canine kidney cells alters epithelial morphology and cha

151 phrogenesis using Tuba knockdown Madin-Darby canine kidney cells and tuba knockdown in zebrafish.

152 and activity of DbpA and YAP in Madin-Darby canine kidney cells depleted either of ZO-1, or one of t

153 Knockdown of NCX1 in Madin-Darby canine kidney cells induced fibroblastic morphology, inc

154 l NTRp75 and basolateral VSVG in Madin-Darby canine kidney cells still undergo progressive sorting af

155 Madin-Darby canine kidney cells with Na,K-beta knockdown have reduce

156 ole of GRHL2 in tubulogenesis of Madin-Darby canine kidney cells, a process requiring transient, part

157 In contrast to monolayered Madin-Darby canine kidney cells, hepatocytic epithelial cells, which

158 nhibition of NCX1 by KB-R7943 in Madin-Darby canine kidney cells, LLC-PK1, and human primary renal ep

159 f epithelial cell colonies using Madin-Darby canine kidney cells.

160 African green monkey kidney and Madin-Darby canine kidney cells.

161 Here, using Madin-Darby canine kidney epithelial cells grown in 3D culture, we s

162 to GJs when expressed in HeLa or Madin-Darby canine kidney epithelial cells.

163 estingly, transwell assays using Madin-Darby canine kidney II cell line cells stably expressing speci

164 und to be susceptible, including Madin-Darby canine kidney type II (MDCK II) cells.

165 ments within monolayers of MDCK (Madin Darby canine kidney) cells.

166 embryonic kidney) and polarized (Madin-Darby canine kidney) renal cell lines and electrophysiology on

167 ia from kidney epithelial cells [Madin-Darby canine kidney-II (MDCK-II)], which sense fluid flow in r

168 ion potential duration (APD) were studied in canine left ventricular subendocardial slabs using micro

169 Canine leishmaniasis (CanL) is a chronic fatal disease o

170 The diagnosis of canine leishmaniosis (CanL) is complex due to its variab

171 ding tools for the control and prevention of canine leishmaniosis (CanL), including new preventative

172 The best carboplatin model utilized canine lines for gene identification and model training,

173 -closing cycles with a 20-N mandibular right canine load.

174 Canine lymphoma resembles human lymphoma in many importa

175 ources that are currently available to study canine lymphoma, advantages to be gained by exploiting t

176 s, treatment, and outcomes between human and canine lymphoma.

177 in culture for an indefinite period, whereas canine MaSCs (cMaSCs) lose their growth potential in lon

178 and their close phylogenetic relationship to Canine mastadenovirus A (CAdV A) has raised important qu

179 ibits a close phylogenetic relationship with Canine mastadenovirus A (CAdV A), as previously observed

180 All strains colonized the surface of canine MDCK epithelial and DH82 histiocyte cells and mur

181 M. canis polyvalent antigen distribution in canine meningoencephalitis case brain tissues, were appa

182 marker of iron deposition was validated in a canine MI model (n=18).

183 ic delivery of a rAAV2/8 vector expressing a canine microdystrophin (cMD1) is effective in restoring

184 iruses from five host groups: humans, swine, canine, migratory waterfowl, and terrestrial birds.

185 milarly, engraftment into dystrophic mice of canine MiPs from dystrophic dogs that had undergone TALE

186 dual differentiation observed in murine and canine MiPs.

187 In both the canine model (n = 13) and the clinical cohort (80 CRT ca

188 METHODS AND In a canine model (n=10), ventricular radiofrequency lesions

189 out chronic pericardial inflammation in this canine model and offers a potential alternative to endoc

190 With inherent limitations of the canine model and the concern of such a demanding surgica

191 o a VCA in our dog leukocyte antigen-matched canine model is not dependent on the previous establishm

192 This study shows the utility of this canine model of AD for testing new therapeutic agents.

193 Continuous cold crystalloid perfusion in a canine model of DCD: (1) facilitates aerobic metabolism

194 he transverse tubular system (t-system) in a canine model of DHF.

195 SVD parameter has excellent performance in a canine model of dyssynchrony and is strongly associated

196 he pharmacokinetics in a clinically-relevant canine model of HCA-induced brain injury.

197 We used mixed hematopoietic chimerism in the canine model of major histocompatibility complex-matched

198 of cerebrospinal fluid (CSF) samples from a canine model of MPS I revealed a marked elevation of the

199 in simultaneous (18)F-FDG PET/MR scans of a canine model of myocardial infarct and was demonstrated

200 his study evaluated VEGF-B gene therapy in a canine model of tachypacing-induced dilated cardiomyopat

201 vered at intermediate stages of disease in a canine model of X-linked retinitis pigmentosa (XLRP) cau

202 The 3D biventricular-paced canine model resulted in %dLV and %dT values of -7.1% an

203 zed dogs and created a DTI-based atlas for a canine model which could be used to investigate various

204 In a canine model, free-breathing 3D radial UTE performs bett

205 In the canine model, the median difference in CURE-SVD (range,

206 sensitivity (SI) in a nonhypertensive obese canine model.

207 tion of CTPs from bone marrow aspirates in a canine model.

208 w report pacemaker function of iPSC-CMs in a canine model.

209 levels in relation to the crestal bone in a canine model.

210 MP)-2, under space-making titanium mesh in a canine model.

211 arios were in agreement with observations in canine models and patients.

212 i.v. administration of activated allogeneic canine MSC.

213 membrane binding was conserved in murine and canine muscles.

214 Minute virus of canine (MVC) is an autonomous parvovirus in the genus Bo

215 The bocaparvovirus minute virus of canines (MVC) encodes a small, genus-specific protein, N

216 Minute virus of canines (MVC) is an autonomous parvovirus in the genus B

217 erficial tracts of the spinal cord seen in a canine myelin mutant, suggesting that the mutation preve

218 vements in full width at half maximum of the canine myocardium of 13% +/- 5%, similar to cardiac gati

219 Canines (n=40) were studied with cardiac magnetic resona

220 We performed a survey of 84 canine NHL tumors to identify genes affected by somatic

221 novel genetic commonality between human and canine NHLs and supports the potential utility of cBCLs

222 arose from unvaccinated or under-vaccinated canines, not from a novel CPV strain incapable of being

223 Using the canine NPHP5-LCA model we compared human and canine reti

224 homogenous donor/recipient genetics in mice, canine or non-human primates (NHP), anatomic site of T c

225 robiota and two additional species, from the canine oral sphere and from the environment, are present

226 gene identification and model training, with canine OS tumor data for co-expression.

227 lines that were co-expressed and trained on canine OS tumor data, which accurately predicted clinica

228 from human and canine cancer cell lines, and canine OS tumor datasets.

229 models can successfully predict response in canine OS, which may improve outcome in dogs and serve a

230 ct chemosensitivity and treatment outcome in canine OS.

231 vironment on disease development also favors canine over rodent models.

232 rodents is distinctly different from humans, canine pancreatic endocrine cell distribution is more si

233 lthough the emergence and pandemic spread of canine parvovirus (CPV) are well documented, the carnivo

234 examine capsid substitutions that eliminate canine parvovirus (CPV) infectivity and identify how tho

235 Canine parvovirus (CPV) is a highly contagious pathogen

236 Canine parvovirus (CPV) outbreaks can have a devastating

237 We studied the binding kinetics of canine parvovirus (CPV) variants isolated from raccoons-

238 nized as important hosts in the evolution of canine parvovirus (CPV), a pandemic pathogen of domestic

239 Canine parvovirus type 2 (CPV-2) emerged in 1978 and spr

240 Here, in a study of 18 canine patients with soft tissue sarcoma (STS), CIVO cap

241 pound 25 showed robust effects in rabbit and canine pharmacodynamic models and an acceptable cross-sp

242 increasing evidence that surveillance of the canine population for IAVs is an important component of

243 gin CIV H3N8 (CIV-H3N8), are enzootic in the canine population.

244 under different loading scenarios (incisive, canine, premolar and molar bites) to test the hypothesis

245 xillary dentition by a loss of the permanent canines, premolars and to some extent incisors.

246 heir role in promoting bacterial invasion of canine progenitor epidermal keratinocytes (CPEK).

247 dog movements for the elimination of endemic canine rabies by mass dog vaccination in Region VI of th

248 global burden of human rabies is to control canine rabies rather than expansion of the availability

249 t tolerance to a VCA could be achieved after canine recipients were simultaneously given marrow from

250 Canines remain the gold standard for explosives detectio

251 annels within the tight junction of cultured canine renal tubule or human intestinal epithelial monol

252 for the prevention of disease caused by this canine respiratory pathogen.

253 canine NPHP5-LCA model we compared human and canine retinal phenotypes, and examined the early stages

254 used FEELnc on a real data set comprising 20 canine RNA-seq samples produced by the European LUPA con

255 hallenging by a lack of understanding of the canine's odor environment, which is dynamic and typicall

256 m may therefore contribute to the decline in canine semen quality that parallels that reported in the

257 samples consisting of positive and negative canine sera for VL was accompanied by high sensitivity a

258 nd anti-sand fly saliva IgG were measured in canine sera.

259 within cells have not been demonstrated, the canine serological data indicate that dogs produce an im

260 Remarkably, canine seroprevalence for different HuNoV genotypes mirr

261 for the presence of viral nucleic acid, and canine serum samples were tested for the presence of ant

262 ous exposure to HuNoV was obtained in 43/325 canine serum samples.

263 type 5 constructs encoding large sections of canine SMCY and the entire canine SRY gene.

264 se revealed the external aerodynamics during canine sniffing, where ventral-laterally expired air jet

265 acid motif (SA2,3Gal) in avian, equine, and canine species; the alpha2,6-linked sialic acid motif (S

266 rentiation and myelin formation in the fetal canine spinal cord from E40 to P0.

267 ations performed in the presence of purified canine SRP.

268 large sections of canine SMCY and the entire canine SRY gene.

269 In addition, canine stool samples were analyzed for the presence of v

270 Recent canines studies have shown that iron deposition within c

271 Canine tachypaced dyssynchronous HF and CRT models were

272 morphological analyses reveal that enlarged canine teeth (fangs) originated at the base of the Nemop

273 Periapical lesions were induced in 24 canine teeth of 6 ferrets.

274 After 3 mo, block sections of the canine teeth were imaged radiographically and processed

275 To examine this risk, canine tissues were studied for their ability to bind to

276 addition, a PK/PD method was established in canines to enable preclinical profiling of mouse-inactiv

277 common hippopotamus (Hippopotamus amphibius) canines to quantify herbaceous vegetation change in Quee

278 NM myosin during contractile stimulation of canine tracheal SM tissues.

279 These results supported existing canine training and identified certain areas that may be

280 The instrument was deployed to support canine training in the field, detecting cross-contaminat

281 Developing a canine training regimen is made challenging by a lack of

282 This goal requires canine training to be approached similarly to scientific

283 was to present a case report of a mandibular canine transmigration in a patient aged 12.

284 Canine transmissible venereal tumor (CTVT) is a parasiti

285 Canine transmissible venereal tumors (CTVT) are likely t

286 fficacious and affordable vaccine to control canine-transmitted rabies in developing countries.

287 study is to describe the cytoarchitecture of canine V-SVZ (cV-SVZ), to assess its neurogenic potentia

288 graphy and costs, we predicted the impact of canine vaccination and sterilization on human health out

289 as potential supplemental approaches include canine vaccination and sterilization.

290 nhance IKs amplitude in adult guinea pig and canine ventricular myocytes.

291 g various experimental approaches, since the canine virus emerged from horses approximately 15 years

292 Although equine and canine viruses hardly replicated in the respiratory syst

293 s genetic differences between the equine and canine viruses, this variation did not result in dramati

294 Clinical manifestations in canine visceral leishmaniasis (CVL) have not been clearl

295 In Brazil, human and canine visceral leishmaniasis is caused by infection wit

296 Forty canines were divided into dimethylsulfoxide (DMSO) group

297 located at the upper and lower incisors and canines were treated with a laterally positioned flap.

298 ntracranial electroencephalography from five canines with naturally occurring epilepsy and two humans

299 re and after pericardial resection in normal canines with open (n=3) and closed chest (n=5) and in a

300 that observed with adenosine in 3 groups of canines: without coronary stenosis, subjected to non-flo