ライフサイエンスコーパス: caninum

1 ed by infective hookworm larvae (Ancylostoma caninum).

2 a tenella, Sarcocystis neurona, and Neospora caninum).

3 olated from the canine hookworm (Ancylostoma caninum).

4 gh degree of resistance to infection with N. caninum.

5 protein produced by the hookworm Ancylostoma caninum.

6 s with abortion confirmed to be caused by N. caninum.

7 T-1, a GST from the dog hookworm Ancylostoma caninum.

8 osely related apicomplexan parasite Neospora caninum.

9 ondii is also true for its relative Neospora caninum.

10 tion against congenital transfer of Neospora caninum.

11 apicomplexan protozoan closely related to N. caninum.

12 s anticoagulant activity than extracts of A. caninum.

13 e isolated from the dog hookworm Ancylostoma caninum.

14 Neospora caninum, a causative agent of bovine abortions, is an ap

15 for detection of serum antibody to Neospora caninum, a major cause of bovine abortion.

16 Neospora caninum, a protozoan parasite closely related to Toxopla

17 The routine diagnosis of Neospora caninum abortion is based upon histopathologic changes i

18 inant Ancylostoma secreted protein 1 from A. caninum (Ac-ASP-1) results in protection against hookwor

19 rease in the numbers of mice transmitting N. caninum and a lower frequency of transmission by individ

20 ion in mice that had been vaccinated with N. caninum and challenged with T. gondii was observed.

21 lin-like signals may regulate recovery of A. caninum and could be potential targets for antihelminthi

22 ed by coccidian parasites including Neospora caninum and Eimeria tenella.

23 these parasites and present evidence that N. caninum and H. heydorni are separate species.

24 Neospora caninum and Hammondia heydorni are two coccidian parasit

25 canine parvovirus, Ehrlichia canis, Neospora caninum and perhaps rabies virus, but not with exposure

26 ds of the dog-infecting hookworm Ancylostoma caninum and the human-infecting hookworm Ancylostoma cey

27 ing stage of the canine hookworm Ancylostoma caninum and vaccinated dogs with the purified protease.

28 f exposure of polar bears to C. burnetii, N. caninum, and F. tularensis.

29 nsferase from the adult hookworm Ancylostoma caninum, and its possible role in parasite blood feeding

30 a system specifically designed for Neospora caninum, and used this system as a heterologous platform

31 hookworm Ancylostoma caninum termed AcAP (A. caninum anticoagulant protein).

32 s to the cELISA included capturing native N. caninum antigen with a parasite-specific MAb (MAb 5B6-25

33 inhibited by mild periodate treatment of N. caninum antigen, demonstrating the carbohydrate nature o

34 -reactive antibodies recognizing multiple N. caninum antigens by immunoblot assay, did not inhibit bi

35 mechanisms involved in protection against N. caninum-associated abortions.

36 olated from the canine hookworm (Ancylostoma caninum), binds to the I domain of CD11a and CD11b and i

37 of 8 fetuses that had typical lesions of N. caninum but were immunohistochemistry negative, indicati

38 In summary, the modified N. caninum cELISA provided a simple, rapid, and versatile m

39 membrane of the canine hookworm, Ancylostoma caninum, contains aspartic proteases (APR-1), cysteine p

40 ays/networks for Toxoplasma gondii, Neospora caninum, Cryptosporidium and Theileria species, and Babe

41 bial protein in the N. caninum tachyzoite N. caninum cyclophilin (NcCyP) as a major component of the

42 ne potently inhibits in vitro recovery of A. caninum dauer arrest.

43 cattle experimentally infected with Neospora caninum develop parasite-specific CD4+ cytotoxic T lymph

44 In fresh or frozen tissues, PCR detected N. caninum DNA in 10 of 13 true-positive fetuses (77%) and

45 d paraffin-embedded tissues, PCR detected N. caninum DNA in 13 of 13 true-positive fetuses (100%) and

46 PCR also detected N. caninum DNA in 6 of 8 fetuses that had typical lesions o

47 PCR detection of N. caninum DNA in formalin-fixed, paraffin-embedded tissues

48 N. caninum DNA was amplified most consistently from brain t

49 that Nod2-dependent responses account for N. caninum elimination.

50 rnetii, Francisella tularensis, and Neospora caninum, estimate concentrations of persistent organic p

51 this approach, we here demonstrated that N. caninum expressing T. gondii's GRA15 and ROP16 kinase ar

52 N. caninum expressing TgGRA15 differentially disturbed the

53 On the other hand, N. caninum expressing TgROP16 induced host STAT3 phosphoryl

54 e IkappaB kinase activity was detected in N. caninum extracts, thereby implying that this parasite is

55 d in dermatological lesions, and Ancylostoma caninum has been associated with eosinophilic enteritis

56 ogs in 1984, the protozoan parasite Neospora caninum has been found to infect a wide range of animals

57 In cattle, N. caninum has particular significance as a cause of aborti

58 oluble protein extracts of adult Ancylostoma caninum hookworms.

59 sera defined by fetal histopathology and N. caninum immunohistochemistry and by maternal N. caninum

60 rching the vertical transmission of Neospora caninum in cattle that the terms 'vertical', 'congenital

61 and characterization of CTL responses to N. caninum in the natural, outbred, bovine host will facili

62 inum immunohistochemistry and by maternal N. caninum indirect fluorescence assay (IFA) at a 1:200 ser

63 NF-kappaB subunit p65 was not detected in N. caninum-infected cells, although this host transcription

64 Four N. caninum-infected Holstein cattle developed NcSRS2 peptid

65 transfer of CD8+ T-cell splenocytes from N. caninum-infected mice was protective against challenge w

66 subsets indicated that CD4(+) CTL killed N. caninum-infected, autologous target cells and that killi

67 Bovine abortions due to Neospora caninum infection are a major cattle-production problem

68 Confirmation of N. caninum infection by immunohistochemistry has low sensit

69 zes several pathogens and its role during N. caninum infection has not yet been described.

70 Current diagnostic methods for N. caninum infection in cattle and the advances necessary t

71 tochemistry determined the true status of N. caninum infection in each fetus.

72 examined the utility of PCR in detecting N. caninum infection in fetal tissues from spontaneous bovi

73 d versatile method to accurately identify N. caninum infection status in cattle using a single cutoff

74 or-mediated apoptosis is repressed during N. caninum infection, and the data further showed that the

75 of mice with either third-stage Ancylostoma caninum infective hookworm larvae (L3) or alum-precipita

76 from the hematophagous nematode Ancylostoma caninum inhibit blood coagulation with picomolar inhibit

77 Neospora caninum is a coccidial protozoan parasite that appears m

78 The protozoan Neospora caninum is a primary infectious cause of abortion in cat

79 cate that heterologous gene expression in N. caninum is a useful tool for the study of specific gene

80 Neospora caninum is an apicomplexan parasite responsible for majo

81 Neospora caninum is an apicomplexan parasite that is closely rela

82 Neospora caninum is an obligate intracellular protozoan parasite

83 fection with the protozoan parasite Neospora caninum is emerging as a major cause of reproductive los

84 study was conducted to establish whether N. caninum is similarly capable of subverting apoptotic pat

85 olated from the canine hookworm (Ancylostoma caninum), is a beta2 integrin antagonist that inhibits P

86 he intracellular protozoan parasite Neospora caninum, is fatal when there is a complete lack of IFN-g

87 o analyze several independent and diverse N. caninum isolates; both antigens were recognized in all i

88 e the anatomic sites of expression within A. caninum L3 to secretory granules in the glandular esopha

89 A. caninum larvae migrate through mouse lungs, with maximal

90 did not amplify Toxoplasma gondii, Neospora caninum, Leishmania infantum, Cryptosporidium parvum, or

91 that coyotes (Canis latrans) can excrete N. caninum oocysts in their feces and that white-tailed dee

92 nterest, including Eimeria tenella, Neospora caninum, Plasmodium falciparum, Sarcocystis neurona and

93 The hematophagous hookworm Ancylostoma caninum produces a family of small, disulfide-linked pro

94 ted genes of Toxoplasma gondii, driven by N. caninum promoters, have yielded robust expression and co

95 These observations demonstrate that N. caninum protects against lethal T. gondii infection by t

96 PVM) of T. gondii was not apparent on the N. caninum PVM.

97 Cattle infected with Neospora caninum readily experience transplacental parasite trans

98 activated larvae of the hookworm Ancylostoma caninum released a 42-kDa protein, termed Ancylostoma-se

99 The dog hookworm Ancylostoma caninum secretes an astacin-like metalloprotease, Ac-MTP

100 In this study, N. caninum-specific CTL expanded from peripheral blood mono

101 sting of the 4,323 bovine sera of unknown N. caninum status revealed a distinct bimodal distribution

102 e, and a set of 4,323 cow sera of unknown N. caninum status.

103 The binding of MAb 4A4-2 to N. caninum tachyzoite antigen was consistently inhibited by

104 Immunoblot analysis of N. caninum tachyzoite antigens with sera from cows with con

105 In N. caninum tachyzoite culture supernatant, three NcCyP band

106 inum tachyzoite lysate antigen (NcAg) and N. caninum tachyzoite culture supernatant.

107 Abundant NcCyP was detected in whole-cell N. caninum tachyzoite lysate antigen (NcAg) and N. caninum

108 has identified a microbial protein in the N. caninum tachyzoite N. caninum cyclophilin (NcCyP) as a m

109 These results indicate that the N. caninum tachyzoite naturally produces a potent IFN-gamma

110 binds a carbohydrate epitope on a single N. caninum tachyzoite surface antigen that is recognized co

111 ound diffusely to the exterior surface of N. caninum tachyzoites and recognized a single 65-kDa band

112 inoculation consisting of live, avirulent N. caninum tachyzoites followed by virulent challenge durin

113 nated Ncp29 and Ncp35, respectively) from N. caninum tachyzoites that are the predominant antigens re

114 clonal antibody (MAb), MAb 4A4-2, against N. caninum tachyzoites.

115 anticoagulants from the hookworm Ancylostoma caninum termed AcAP (A. caninum anticoagulant protein).

116 In the parasitic nematode Ancylostoma caninum, the dauer larval stage is the infective stage,

117 pathway is not central to the ability of N. caninum to prevent apoptosis of their host cells.

118 asite-specific CTL against transplacental N. caninum transmission in cattle.

119 ecrease the frequency of congenital Neospora caninum transmission.

120 findings support investigation of subunit N. caninum vaccines incorporating NcSRS2 gene sequences or

121 st, a closely related apicomplexan, Neospora caninum, was unable to inhibit IFN-gamma-induced gene ex

122 that were infected intraperitoneally with N. caninum were protected against a lethal challenge from T

123 se Toxoplasma strains but also with Neospora caninum, which is closely related to Toxoplasma but has

124 re thought to be protective against Neospora caninum would be detrimental to the pregnancy.