ライフサイエンスコーパス: canonical

1 y reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure overload-i

2 e] subcluster ([2Fe]H) covalently bound to a canonical [4Fe-4S] cluster ([4Fe-4S]H).

3 2-converting cofactor (H-cluster) in which a canonical [4Fe-4S] cluster is linked to a unique diiron

4 In contrast, canonical Abeta comprised the minority of the identified

5 er to an intersubunit interface containing a canonical ACh binding site or to an alternative interfac

6 Formation of the canonical ACP-linked intermediate with fluoromalonyl-CoA

7 In contrast to canonical actin, P. falciparum actin 1 (PfAct1) does not

8 rdiometabolic effects that are distinct from canonical actions.

9 of AML and play an important role in the non-canonical activation of signal transducer and activator

10 reslin phosphorylation does not occur by the canonical adapter mechanism demonstrated for other subst

11 These findings indicate an uncoupling of the canonical Akt/FoxO1 pathway in HCV protein-expressing he

12 For the canonical Allolevivirus Qbeta the maturation protein, A2

13 ted with channel gating, the fluorescent non-canonical amino acid coumarin-tyrosine was genetically e

14 IMS) and fluorescence-based biorthogonal non-canonical amino acid tagging (BONCAT) - for studying the

15 a cell type of interest and providing a non-canonical amino acid with a chemical handle, we selectiv

16 ifficult and requires the replacement of the canonical amino acids (4R)-hydroxyproline and proline by

17 potent and selective hMC1R agonist with only canonical amino acids.

18 ific labeling of nascent proteins with a non-canonical amino-acid and click chemistry.

19 tramers via a 'three-pronged' combination of canonical and non-canonical mechanisms.

20 we propose a new unbiased method to identify canonical and non-canonical miRNA-binding sites from pea

21 nto the two main classes of these compounds: canonical and non-canonical nucleobases.

22 Despite this, we identify canonical and non-canonical skin pigmentation loci, incl

23 veled (Dsh/Dvl) transduces the signal during canonical and non-canonical Wnt signaling.

24 tein sorting 34 (Vps34) plays a role in both canonical and noncanonical autophagy, key processes that

25 her abundance of transcripts associated with canonical and noncanonical inflammasomes was detected in

26 ng" enzyme responsible for the catabolism of canonical and noncanonical nucleoside triphosphates (dNT

27 ometry and protein expression; activation of canonical and noncanonical pathways was examined in peri

28 ed into the inclusion membrane, displays one canonical and one noncanonical FFAT motif that cooperati

29 t and MEF2C occupancy at promoters harboring canonical and variant MEF2C motifs.

30 Cuntz algebra [Formula: see text] or of the canonical anticommutation relations (CAR) algebra.

31 f the blood pressure effects associated with canonical APJ activation.

32 However, this canonical approach works in limited conditions, such as

33 Importantly, unlike the canonical approach, an optimal experiment to identify pa

34 While both antibodies share a canonical asparagine-glycine (NG) motif in a structural

35 ombination of these alternative pathways and canonical autophagy blockade, results in dramatic nuclea

36 t not in macrophages defective in a related, canonical autophagy pathway (Atg14, Ulk1, or cGAS).

37 Collectively, our data identify the canonical autophagy pathway in DCs as a molecular target

38 stic target of rapamycin complex 1-dependent canonical autophagy, GC B cell autophagy occurred predom

39 Ps, all of which are known to be involved in canonical autophagy.

40 This lysosomal targeting is independent of canonical autophagy: both WT and Atg5(-/-) mouse embryon

41 hat MOSP destined for the TDE OM follows the canonical BAM pathway, while formation of a stable perip

42 ine, which was chosen to favor nucleation of canonical beta-turn secondary structures.

43 the inhibitor: a major conformer (70%) with canonical bidentate hydroxamate-Zn(2+) coordination geom

44 icomplexan parasites, which do not divide by canonical binary fission but undergo unconventional cycl

45 endent manner, preventing its recruitment to canonical binding-sites in the promoters of Nanog, Oct4

46 t FTase can modify sequences longer than the canonical CAAX sequence, specifically C(x)3X sequences w

47 PM3 by Gbetagamma subunits, rather than by a canonical cAMP mediated mechanism.

48 igate the effects of Vps34 inhibition on the canonical cAMP response elicited by beta2AR activation.

49 ompared the distribution of mutations in 119 canonical cancer genes.

50 cerol (2-AG) and anandamide (AEA) activate a canonical cannabinoid receptor in Caenorhabditis elegans

51 Thus, the next step in this canonical case of coevolution after a species jump has b

52 he genetic determinants responsible for this canonical case of virulence evolution remain to be deter

53 of cell death does not fall into one of the canonical categories such as apoptosis, necrosis, parapt

54 psin coupled to transient receptor potential canonical cation channels.

55 ) that fully automates the classification of canonical cell populations and highlights novel cell typ

56 NP-N and CENP-C decode and stabilize the non-canonical CENP-A nucleosome to enforce epigenetic centro

57 cation channel, transient receptor potential canonical channel 6 (Trpc6), in isolated myocytes.

58 The transient receptor potential canonical channel-1 (TRPC1) is a Ca(2+)-permeable channe

59 loading by RecBCD, without the influence of canonical Chi signals.

60 n and around the primary cilium, making JS a canonical ciliopathy.

61 e sensory cortex (S1), mouse M1 also has the canonical circuit motif of a core thalamic input to the

62 sitic activity similar to that achieved with canonical cis-4'' substitution.

63 l description for a network of heterogeneous canonical Class 1 inhibitory neurons which includes the

64 is mirrored by changes in expression of the canonical clock genes Period1 and Period2 (Per1 and Per2

65 een the biological activities of CNbeta1 and canonical CNbeta2.

66 transcription of an mRNA, despite carrying a canonical coding sequence, can directly cause gene repre

67 hat different frequency bands index distinct canonical computations.

68 other five CDR loops, CDR H3 does not adopt canonical conformations and must be modeled de novo.

69 metabolism and lack of information about non-canonical connections between metabolites limits the sco

70 ent a combined framework, cascaded multiview canonical correlation (CaMCCo), for fusion and cascaded

71 In this context, we used sparse canonical correlation analyses (sCCAs) to determine the

72 inear discriminant analysis (LDA) and sparse canonical correlation analysis (CCA) were used to assess

73 techniques such as various structured sparse canonical correlation analysis (SCCA) algorithms have be

74 Sparse Canonical Correlation Analysis (SCCA) has been a popular

75 stimate metabolic connectivity and conducted canonical correlation analysis of metabolic activity and

76 present fCCAC, an application of functional canonical correlation analysis to assess covariance of n

77 Specifically, sparse canonical correlation analysis was conducted on 3 featur

78 Using canonical correlation analysis, we sought separable mult

79 Canonical correlations and hierarchical clustering techn

80 y repeated 7-amino-acid sequence, called the canonical CTD, which orchestrates various steps in mRNA

81 resistance to oxidative stress required the canonical CXXC redox-sensing motif.

82 accommodates the hydrophobic sidechains of a canonical D-site, retaining a significant degree of diso

83 its RQC domain, which is different from the canonical damage response at genomic sites via its HRDC

84 Using a canonical dataset of Californian bird surveys and a dete

85 of 343485 MITE putative sequences, including canonical, diverse and partial ones, were delineated fro

86 In the canonical DNA double helix, Watson-Crick (WC) base pairs

87 ructure of cognitive function, in terms of a canonical domain-general cognitive process, and various

88 They comprise three canonical domains for antigen recognition, T cell activa

89 orce each other to enhance signaling through canonical downstream second messengers, a phenomenon we

90 nocytes uniformly express high levels of the canonical E-selectin binding determinant sialyl Lewis X

91 tilizing Ubc5BF62A, defective in binding the canonical E2 site, demonstrate that the cryptic Site 1 i

92 therefore studying electrophysiology beyond canonical electrically excitable cells could yield excit

93 Manipulation of canonical endocytic pathways only slightly influenced pr

94 Their partial co-localization with canonical endosomal markers thus reflects their rapid fl

95 hosts of SIV express very low levels of the canonical entry coreceptor CCR5, and recent studies have

96 We recently described a non-canonical ER quality control mechanism for folding of th

97 ng roles of ETR1 and ETR2 do not require the canonical ethylene signaling pathway.

98 It is well established that canonical eukaryotic pre-mRNA 3' processing is carried o

99 bit populations of Australia and Europe is a canonical example of host-pathogen coevolution.

100 se transition in vanadium dioxide (VO2) is a canonical example of such correlations.

101 The canonical explanation for this effect is that frames dif

102 ty tuning curves, but may rather represent a canonical feature of neural encoding.

103 Our previous work found that canonical forms of transition state theory incorrectly p

104 siological concentration, although the grand canonical free energy profiles are uphill for HTT exon 1

105 found conserved spectral patterns among the canonical frequency bands (delta 0-3 Hz, theta 3-7 Hz, a

106 endomembrane locations, in addition to their canonical function at the cytoplasmic surface of the pla

107 moothened (SMO) inhibition, suggesting a non-canonical function of PTCH1.

108 A canonical fungal mitochondrial genome was recovered from

109 ts favoring beta-arrestin-2 recruitment over canonical G protein activation.

110 species such as Arabidopsis having a single canonical Galpha, this rate could be affected by regulat

111 d (eCB) system regulates DA release and is a canonical gatekeeper of goal-directed behavior.

112 ding of how genomes are designed and how the canonical genetic code evolved.

113 emonstrate that GBAi does not interfere with canonical GPCR-G protein signaling but blocks GBA-depend

114 Canonical growth factors act indirectly via receptor-med

115 P-Glu stimulation enhanced the activation of canonical growth signalling pathways ERK1/2 and AKT.

116 n interactions were comparable to those of a canonical GTPase with an effector.

117 The epithelium showed no evidence of canonical hedgehog signaling, and hyperproliferation was

118 Instead of a canonical helix, a noncanonical herringbone helix is for

119 In addition to the canonical histones, there are also variant histones that

120 ryptic peptides representing essentially all canonical human gene products, and we exemplify the util

121 eractions of BH3-only proteins with both the canonical hydrophobic binding groove (alpha2-5) and alph

122 priming by inhibiting the activation of non-canonical IkappaB kinase varepsilon and IkappaBalpha, an

123 t adaptive NK cells are more long-lived than canonical, immunoregulatory NK cells.

124 Canonical IN types conserved across distinct cortical re

125 in was essential for TcpB to subvert the non-canonical inflammasome activation as a TcpB(G158A) mutan

126 K subunits, IKKalpha and IKKbeta, during the canonical inflammatory response.

127 these SPIs can be categorized into serpins, canonical inhibitors and alpha-2-macroglobulins (A2Ms).

128 mRNAs continues via the eIF2D-dependent non-canonical initiation pathway.

129 found that UIS3 binds host LC3 through a non-canonical interaction with a specialized surface on LC3

130 enerating after its excision, a newly formed canonical intron defined as 'external'.

131 Discordant canonical introns, one nt apart, are present in yet othe

132 The activation of this response is non-canonical, involving a regulatory mechanism requiring th

133 ctivated X-box binding protein 1 (XBP1), the canonical IRE1alpha target.

134 fic signature for interclass complexation of canonical J-proteins.

135 Canonical JAK-STAT signaling is pivotal for long-term de

136 nscriptional activity, and is independent of canonical Jak2 signaling.

137 nts a completely different fold from that of canonical K(+) channels.

138 ylation was localized to two variants of the canonical KIN10 recognition sequence, one in each of its

139 While WRI1 lacks canonical KIN10 target sequences, we demonstrated direct

140 s revealed that this signal does not require canonical ligand induction.

141 just the structures to accommodate these non-canonical linkages (Proc.

142 ember LC3B, binds directly to PCM1 through a canonical LIR motif.

143 similar correlation coefficients, and better canonical loading profiles than the competing methods.

144 s Pol alpha, Pol delta, and Pol epsilon; and canonical maturation of Okazaki fragments into continuou

145 endent kinase (PDK) 1 pathway represents the canonical mechanism for phosphorylation of Akt at its pr

146 r of the elusive post-chemistry steps in the canonical mechanism of a DNA polymerase.

147 LTPpre induction involves a non-canonical mechanism of retrograde nitric oxide signallin

148 Although the canonical mechanism of translation initiation has been s

149 geted to the proteasome for degradation (the canonical mechanism).

150 ee-pronged' combination of canonical and non-canonical mechanisms.

151 Epimetabolites are produced from canonical metabolites by defined enzymatic reactions and

152 we show that tRF biogenesis does not rely on canonical microRNA/siRNA processing machinery (i.e., ind

153 .8 to -4.6 per mil ( per thousand), than the canonical mid-ocean ridge basalt value of -6.0 per thous

154 een miRNA and target mRNAs, but rather a non-canonical miRNA targeting activity outside the seed or w

155 nbiased method to identify canonical and non-canonical miRNA-binding sites from peaks identified by A

156 d half-phased miRNA-like RNAs different from canonical miRNAs from cassava miRNA precursors detected

157 molecular level we provide evidence for non-canonical mode of action of Wnt5a and its regulation ove

158 A canonical model entails a C1r2s2 with its serine proteas

159 The canonical model of DNA replication describes a highly-pr

160 o regulation by monocular deprivation is the canonical model of plasticity confined to a critical per

161 In contrast to canonical models, we observed that Bicoid binds to DNA w

162 Grand canonical Monte Carlo (GCMC) simulation provides microsc

163 semblies from double crossover (DX) tiles, a canonical motif in DNA nanotechnology.

164 by reshuffling base pairs in and around non-canonical motifs.

165 ends inflicted during tRNA splicing and non-canonical mRNA splicing in the fungal unfolded protein r

166 Here, we demonstrate that the canonical Musashi2 isoform is subject to similar regulat

167 sting the existence of an alternative to the canonical MutS-MutL-based MMR.

168 transcription of this isoform represses the canonical NDC80 mRNA expression in cis, thereby inhibiti

169 These dual roles of canonical NF-kappaB in Tconv and Treg cells highlight th

170 ion of TLR signaling pathways implicated the canonical NF-kappaB pathway and the proinflammatory cyto

171 sible for the preferential activation of non-canonical NF-kappaB pathway in LPS-conditioned DCs.

172 It operates via subversion of the canonical NF-kappaB pathway, which requires a physical i

173 lation appeared to require activation of the canonical NF-kappaB pathway.

174 kappaBalpha, 2 bona fide target genes of the canonical NF-kappaB pathway.

175 , we identified that conditional deletion of canonical NF-kappaB signaling (p65) in myeloid cells inh

176 BCR-mediated canonical NF-kappaB signaling was impaired in all mature

177 IKKbeta plays a central role in the canonical NF-kB pathway, which has been extensively char

178 inase beta (CA-IKKbeta), a key kinase in the canonical NFkappaB pathway.

179 motes DNA double-strand break repair via the canonical nonhomologous end joining (c-NHEJ) pathway.

180 In contrast to canonical Notch activation initiated by adjacent ligand-

181 it-1 mRNA or, potentially, by modulating the canonical Notch pathway.

182 Although the canonical Notch signaling pathway is well characterized,

183 Although Hairless (H) is the canonical nuclear Notch pathway inhibitor, and H heteroz

184 lasses of these compounds: canonical and non-canonical nucleobases.

185 eosome states (PANS) are as important as the canonical nucleosome structure for the understanding of

186 ctivity, when the catalytic glutamate of the canonical nucleotide binding site 2 was mutated to gluta

187 ng of adenine and guanine nucleotides to the canonical nucleotide binding sites of the regulatory Bat

188 This nuclear signaling is established as the canonical or type 1 pathway for TH action.

189 quaternary structure did not conform to the canonical pairing expected for class III enzymes.

190 Non-canonical pairs can be predicted using a knowledge-based

191 y structure, allow accurate inference of non-canonical pairs, an important step towards accurate pred

192 tor (IL-1R) families transduce signals via a canonical pathway involving the MyD88 adapter and the in

193 the primary transducer of the Wnt signaling canonical pathway, and IWP2, a wide action Wnt signal bl

194 Top canonical pathways represented by these mRNAs include Wn

195 hat are predicted by enzyme promiscuity from canonical pathways.

196 Contravening the canonical phagocytic pathway, tPCs mature by fusing with

197 in of the ISWI subunit BAZ1B and for the non-canonical PHD and bromodomain modules of the paralog BAZ

198 Despite the canonical picture of LacI diffusing rather freely, in re

199 Canonical, PLZF-expressing NK cells were retained in asy

200 ts demonstrate that inhibition or slowing of canonical pre-mRNA processing events shifts the steady-s

201 We found that the canonical principle of Marginal Value Theorem (MVT) also

202 representing different manifestations of the canonical process, is a fundamental organization of huma

203 cular recognition fundamentally differs from canonical promiscuous chaperone-substrate interactions.

204 gene promoters and led to downregulation of canonical PU.1 transcriptional targets.

205 utive chemokine CXCL12, which also binds the canonical receptor CXCR4, and CXCL11, which also binds C

206 an Hsp70-client interaction and involved non-canonical regions of the chaperone.

207 Trypanosomes possess two canonical RNA poly (A) polymerases (PAPs) termed PAP1 an

208 C-terminal alpha-helical region obscures its canonical RNA-binding surface.

209 ow these si/shRNAs kill cancer cells through canonical RNAi by targeting the 3'UTR of critical surviv

210 Thus, in addition to their canonical role in protein recycling, REs also mediate fo

211 Thus, in addition to their canonical roles in mitochondrial fission, Mff and Drp1 a

212 o as heterochromatin, suggesting further non-canonical roles of the proteasome in gene expression.

213 s an intertwined two-domain arrangement of a canonical RRM and second domain.

214 f miRNA-binding activity does not follow the canonical rule about the seed matching between miRNA and

215 , and trypanosomes do not follow many of the canonical rules developed for other eukaryotic N-glycosy

216 late that viral terminases cleave DNA by the canonical RuvC-like mechanism.

217 BTH)-regulated genes, including ICS1 and the canonical SA marker gene, PR1.

218 used in concert with prior knowledge of the canonical secondary structure, allow accurate inference

219 Foraging has been a canonical setting for studying reward seeking and inform

220 stal structures showed that pT1471 binds the canonical SH2 pY site while pS1493 binds an unanticipate

221 a indicates that the activation of NF-kappaB canonical signaling by Notch-4/Int3 is ANK repeats depen

222 ss bitter taste receptors (TAS2Rs) and their canonical signaling components (i.e., G-protein gustduci

223 neither ErbB4-induced phosphorylation of the canonical signaling pathway effectors Erk1/2, Akt, or ST

224 beal2 and points to the dysregulation of the canonical signaling pathway of Dock7 as a possible cause

225 ic network analysis identified that 46 and 6 canonical signaling pathways were significantly targeted

226 with Egfr, which cannot be explained by the canonical signalling paradigm.

227 thioester formation, whereas binding at the canonical site (Site 2) is associated with polyubiquitin

228 that Cin8 binds microtubules not only at the canonical site, but also one or more separate ("noncanon

229 genetic analyses revealed that ISE2 is a non-canonical Ski2-like RNA helicase that represents a separ

230 Despite this, we identify canonical and non-canonical skin pigmentation loci, including near SLC24A5

231 ion of GC cells, which is different from the canonical SOCE/Ca(2+)-induced apoptosis in other tumors.

232 Minigene assays were performed for two non-canonical splice site variants and revealed missplicing

233 mpared to exonic cores, even after excluding canonical splice sites.

234 "Read-Split-Fly" (RSF), which can detect non-canonical spliced regions with higher sensitivity and im

235 cing did not reveal any pathogenic coding or canonical splicing mutations within the linkage region b

236 s in nucleocytoplasmic shuttling among seven canonical SR protein family members.

237 Translation from non-canonical start codons ranged from 0.007 to 3% relative

238 tension of H-strand transcripts beyond their canonical stop site and that TOP1MT acts as a topologica

239 Oxytocin-modulated DA neurons give rise to canonical striatal projections.

240 the evolution of charge correlations in the canonical stripe-ordered cuprate La1.875Ba0.125CuO4 acro

241 with dimensions comparable with those of the canonical structure described for opisthokonts.

242 NT/X is the only toxin that also cleaves non-canonical substrates VAMP4, VAMP5 and Ykt6.

243 We have found that the canonical surface marker of ASCs, CD138 (syndecan-1), wh

244 e the inhibitory action of this miRNA on its canonical targets such as Notch1 and SIRT1, and on Ras/M

245 variety of other TRAV/TRBV combinations (non-canonical TCRs).

246 this relatively featureless peptide epitope (canonical TCRs).

247 omain, which has no sequence homology to the canonical tetrameric K(+) channels and lacks the TVGYG s

248 ) promotes liver homoeostasis by controlling canonical TGFbeta-SMAD signalling, driving the SMAD1 pat

249 binding to DNA and leads to complete loss of canonical TH action.

250 eg cells upregulated their expression of the canonical TH2 transcription factor GATA3, as well as ST2

251 that the human 7SK snRNP also functions as a canonical transcription factor that, in collaboration wi

252 ates vascular barrier function through a non-canonical, transcription-independent signalling mechanis

253 ously shown that angiotensin II (Ang II) via canonical transient receptor potential 6 (TRPC6) channel

254 smooth muscle cells (VSMCs), stimulation of canonical transient receptor potential channel 1 (TRPC1)

255 lls (VSMCs), stimulation of SOCs composed of canonical transient receptor potential channel 1 (TRPC1)

256 a short timescale that is inconsistent with canonical trkB signaling pathways, suggesting a noncanon

257 Here, we found that a member of the canonical TRP channel family, TRPC3, is highly expressed

258 pothesized that transient receptor potential canonical type 3 (TRPC3) channels are involved in hypoth

259 Two varieties of dsRBD exist: canonical Type A dsRBDs interact with dsRNA, while non-c

260 Type A dsRBDs interact with dsRNA, while non-canonical Type B dsRBDs lack RNA-binding residues and in

261 ricyclic ABC-ring system commonly present in canonical-type strigolactones but feature an open-chain

262 ular localization and phosphorylation by non-canonical upstream kinases.

263 To dissociate canonical versus noncanonical functions of DGCR8, we com

264 tional features of the ipRGC system that are canonical versus species-specific.

265 In contrast to the canonical view that principal cell discharges dominate i

266 ns or a cancer germline antigen, rather than canonical viral antigens.

267 te that different mechanisms, other than the canonical VSD-pore coupling, are at work in voltage-depe

268 e incoming nucleotide is bound in either the canonical Watson-Crick base pair or a nonplanar base pai

269 The canonical Wnt pathway regulates numerous fundamental pro

270 rain barrier integrity are controlled by the canonical Wnt pathway.

271 order to activate the beta-catenin-dependent canonical Wnt pathway.

272 n, it is an autocrine/paracrine activator of canonical WNT signaling and, as an intracellular protein

273 We tested C-82, a therapeutic that inhibits canonical Wnt signaling by blocking the interaction of t

274 in NMPs functions in tight coordination with canonical Wnt signaling during the epithelial to mesench

275 nal patterns exhibited evidence of activated canonical Wnt signaling in both types of adenomas, with

276 We show here that loss of Trp53 activates canonical WNT signaling in these SOX2-enriched cultures.

277 Cotreatment with a canonical Wnt signaling inhibitor attenuated but did not

278 bilizes nuclear beta-catenin, and stimulates canonical Wnt signaling more effectively than wild-type

279 uired to localize Dsh to the membrane during canonical Wnt signaling placing Dsh downstream of Arrow.

280 Canonical Wnt signaling was impaired in LGR4-deficient b

281 expression of Axin2, an endogenous target of canonical Wnt signaling, in the developing palatal mesen

282 with either lithium chloride, an agonist of canonical Wnt signaling, or the DKK inhibitor IIIC3a res

283 ene encoding beta-catenin that also activate canonical WNT signaling.

284 ansduces the signal during canonical and non-canonical Wnt signaling.

285 utions of Wnt versus RSPO ligands to in vivo canonical Wnt signalling and ISC biology remain unknown.

286 maps of the developing skeleton, we identify canonical Wnt signalling as a candidate for transducing

287 These surrogates demonstrate that canonical Wnt signalling can be activated by bi-specific

288 toma, accompanied by reduced cerebrovascular canonical Wnt-beta-catenin signaling.

289 Functionally, mature WNT-5A attenuated canonical WNT-driven alveolar epithelial cell wound heal

290 an antagonistic role for Ror2 in regulating canonical Wnt/beta-catenin activity in vivo, where lenti

291 shRNA depletion of Ror2 expression augmented canonical Wnt/beta-catenin signaling activity across mul

292 These findings are significant because the canonical Wnt/beta-catenin signaling pathway promotes ne

293 l fibroblasts through p38 MAPK regulation of canonical Wnt/beta-catenin signaling, increasing alpha-S

294 ell as precise molecular control via the non-canonical Wnt/planar cell polarity pathway, Shh/BMP sign

295 of its downstream protein GSK-3 through the canonical WNT4 pathway which involved in the behavioral

296 CCN1 induces the expression of the non-canonical Wnt5a in pericyte but not in EC cultures.

297 dantly, treatment of mice with TNP470, a non-canonical Wnt5a inhibitor, reestablishes endothelial exp

298 these data demonstrate a FOXC1-elicited non-canonical WNT5A signaling mechanism comprising NF-kappaB

299 derlying rib meristem, without affecting the canonical WUSCHEL-CLAVATA meristem size regulators (3) .

300 that mouse and human germ cells exhibit non-canonical X dosage states that differ from the soma and