ライフサイエンスコーパス: capacity of @3 to

1 An extremely high absorption capacity of CO2 (up to 1.69 mol mol(-1) ) in aminopolyca

2 ntal study considers ride-sharing with rider capacity of up to 10 simultaneous passengers per vehicle

3 onal connectivity biases for short dispersal capacities of organisms (6 m to 16 m).

4 irst time, an extremely high gravimetric CO2 capacity of up to 22 wt % (1.65 mol mol(-1) ) and excell

5 of TTP by MK2, whereas retained RNA-binding capacity of TTP-AA to 3'UTRs caused profound changes in

6 present work explored the lipid antioxidant capacity of citrus pectin addition to 5%(w/v) linseed/su

7 ts including an enhancement of H2 adsorption capacities of up to 57%.

8 The electron deficiency and strong bonding capacity of boron have led to a vast variety of molecula

9 le reporter ion series improves multiplexing capacity of CMT with respect to a commercially available

10 tion of the photosynthetic apparatus and the capacity of the cells to acclimate to different light co

11 king of the phospholipids, which reduces the capacity of the membranes to accommodate inserted melitt

12 arately because entry time could reflect the capacity of an ACO to achieve savings.

13 The capacity of AZ1729 to act at FFA2 receptors to inhibit b

14 These findings highlight the capacity of DA neurons to act as metabolic sensors by re

15 However, multiple factors can impair the capacity of forests to act as carbon sinks; prominent am

16 the presence of IgM or IgA RF increased the capacity of ACPA-IC to activate the complement cascade.

17 IL-10 production, which in turn reduced the capacity of DCs to activate regulatory T cells.

18 to asthma pathophysiology by increasing the capacity of IL-13 to activate intracellular signaling pa

19 nsal duodenal bacteria and characterized the capacity of the produced peptides to activate gluten-spe

20 The capacity of S. aureus to adapt to different host species

21 ing the major mechanisms that will drive the capacity of seagrass seedlings to adapt and survive to w

22 t speech comprehension is not limited by the capacity of theta oscillations to adapt to syllabic rate

23 ulated with aging, this may suggest that the capacity of microglia to adequately produce IL-10 may be

24 Here, we quantify climate connectivity, the capacity of landscape configuration to allow species mov

25 een clinical isolates and corresponds to the capacity of each isolate to alter S. aureus antibiotic s

26 The capacity of grass species to alter their reproductive ti

27 Despite the capacity of invasive alien species to alter ecosystems,

28 The capacity of microbial pathogens to alter their host trop

29 The capacity of pneumococci to adhere to and infect lower ai

30 To evaluate the capacity of a widespread ectotherm to anticipated enviro

31 Embryonic development relies on the capacity of progenitor cells to appropriately respond to

32 We also examine the capacity of regional regulatory monitoring to assess and

33 These paradigms were also used to test the capacity of OXR antagonists to attenuate acute cocaine-e

34 t in the accumbens core with ceftriaxone the capacity of acute stress to augment the acquisition of c

35 Druggability refers to the capacity of a cellular target to be modulated by a small

36 This allows the absolute sequence capacity of a given protein to be approximately predicte

37 The capacity of chemicals to be biotransformed in fish was f

38 r protein rabconnectin-3alpha, determine the capacity of GnRH neurons to be activated by kisspeptin a

39 ca epidemic and that this change altered the capacity of GP to be activated by host factors, enhancin

40 This limits the potential capacity of these organisms to benefit from the antioxid

41 Here, we tested whether the capacity of anti-HLA antibodies to bind complement compo

42 n or gene conversion is not dependent on the capacity of BabA protein to bind Leb, which suggests tha

43 was not dependent on Le(b) expression or the capacity of BabA to bind Le(b).

44 To clarify CST mechanism, we examined the capacity of CST to bind and resolve DNA structures found

45 we reveal that this adaptation enhances the capacity of CV-A24v to bind sialic acid.

46 Moreover, cortistatin reduced the capacity of endothelial cells to bind and recruit immune

47 The capacity of fluorescently labeled AgLDL to bind to funct

48 these paradoxical findings and show that the capacity of LYVE-1 to bind HA is strictly dependent on a

49 that the stoichiometry strongly affects the capacity of magnetite to bind not only quinolone antibio

50 oinhibited WT filamin, but surprisingly, the capacity of these ligands to bind the P2204L mutant was

51 ing the specialized functions and cross-talk capacity of these DC subsets to boost tumor-reactive T c

52 Here we demonstrate the capacity of a synthetic foldamer to capture structure in

53 The capacity of these artificial hosts to catalyze Knoevenag

54 The capacity of HIV-1 to cause disease depends on the virus'

55 The capacity of the hemodialysis equipment to clear chlorami

56 hepatocytes and could contribute to the weak capacity of this cell type to clear HBV infection.

57 er" are important factors in determining the capacity of corals to adapt to climate change through th

58 ral specialisation may modulate the adaptive capacity of species to climate change.

59 exude a yellowish mucilage that promotes the capacity of this plant to climb vertical surfaces.

60 ally challenge social sustainability and the capacity of cities to collectively address environmental

61 the neonatal rat, significantly reduced the capacity of A192PP to colonize the gut, engender double-

62 eletion of misR or misS severely reduced the capacity of N. gonorrhoeae to colonize mice or maintain

63 de that codon optimization is related to the capacity of parasites to colonize multiple hosts.

64 from the marine biosphere and to examine the capacity of biogenic CH4 to compensate for the faint you

65 The capacity of each mAb to compete with patients' IgE for b

66 n with its longer nature, also decreases the capacity of the framework to compress and stabilizes it

67 silicate catalyst, further demonstrating the capacity of the MOF to contain a high concentration of a

68 ng reaction norms is crucial to estimate the capacity of different populations to contend with projec

69 ng provide a mechanistic explanation for the capacity of intestinal microflora to control liver infla

70 sfA2 by a moderate HS treatment enhances the capacity of seedlings to cope with a subsequent severe H

71 ngle miRNA locus (miR-iab4/iab8) affects the capacity of the larva to correct its orientation if turn

72 on can be achieved by utilising the inherent capacity of cells to create highly sophisticated supramo

73 enance of splenic CD8alpha(+) DCs and in the capacity of these cells to cross-present cell corpse-ass

74 els of aggregation-prone proteins exceed the capacity of the proteasome to degrade them.

75 tions, health priorities, financing, and the capacity of the health system to deliver the vaccine.

76 We demonstrated the capacity of the Hex nanocarrier to deliver functional an

77 rts, and funding has broadened the reach and capacity of the VA to deliver direct-acting antiviral (D

78 The capacity of Fractofusus to derive adult morphology by tw

79 Assessing the capacity of surveillance systems to detect these threats

80 The capacity of these probes to detect and stage pulmonary f

81 orbent spot (ELISpot) assay that reveals the capacity of memBcs to develop into antibody-secreting ce

82 ngly, stable expression of IRF3 restored the capacity of EML-TA cells to differentiate into mature B-

83 The capacity of neonatal moDCs to differentiate naive CD4 TH

84 of cue detection.SIGNIFICANCE STATEMENT The capacity of learned cues to direct attention and guide r

85 We hypothesized that the capacity of certain drugs to directly stimulate the inna

86 The capacity of crystallography to directly screen fragment

87 racterize the involvement of oxytocin in the capacity of mice to display emotional state-matching, an

88 ve performance are likely constrained by the capacity of females to dissipate body heat, and not indi

89 ning several miRNAs in a panel increased the capacity of the test to distinguish between colitis-asso

90 omain at S473, thereby expanding the binding capacity of OPTN to diverse Ub chains.

91 RTKs lead to qualitative differences in the capacity of each receptor to drive therapeutic resistanc

92 The capacity of these antibodies to dysregulate the C3 conve

93 TMs have been associated with the capacity of glioma cells to effectively invade the brain

94 The capacity of LSEVh-LS-F to eliminate HIV-1-infected cells

95 The capacity of LSEVh-LS-F to eliminate HIV-1-infected cells

96 nhances lysosomal function and increases the capacity of macrophages to eliminate intracellular patho

97 that speech perception is not limited by the capacity of the auditory system to encode fast acoustic

98 This review focuses on the capacity of complement and TLRs to engage in signaling c

99 subjects, we found lymphopenia and a reduced capacity of T cells to engage glycolysis upon TCR stimul

100 rate environments have examined the adaptive capacity of organisms to enhance our understanding of th

101 We report the capacity of B. pseudomallei to enter, efficiently replic

102 gs point to neonicotinoids causing a reduced capacity of bee species to establish new populations in

103 +) effector responses in differentiating the capacity of high-risk LTRs to establish durable immune c

104 We demonstrate that the capacity of HAV to evade MAVS-mediated type I interferon

105 tasis in the ER disrupts the protein-folding capacity of the ER, leading to eventual neuron death.

106 nued association with FcepsilonRI impede the capacity of desensitized MCs to evoke the calcium respon

107 theoretical and practical issues impede the capacity of agent-based methods to examine and evaluate

108 These results suggest a remarkable capacity of subcortical motor circuits to execute learne

109 other known subdominant epitopes despite the capacity of these mice to expand epitope-specific T cell

110 ation, and summer heat waves could limit the capacity of coast Douglas-fir to extend its growing seas

111 evealed that recombinant ZmEXPB6 acts on the capacity of the walls to extend.

112 Ecosystem health depicts the capacity of system to respond to external perturbations

113 The capacity of cyclodextrins (CDs) to extract phenolic comp

114 iew the existing evidence for the regulatory capacity of OXT to fine-tune general and social anxiety-

115 ether the decoding process is bounded by the capacity of theta rhythm to follow syllabic rhythms in s

116 n, resulting in altered permeability and the capacity of bacteria to form biofilms.

117 skeletal consequences and did not affect the capacity of bone marrow macrophages to form osteoclasts

118 cross-linking experiments that exploited the capacity of Cys-306 to form intermonomeric disulfide bri

119 sed GSC marker expression, and decreased the capacity of GSCs to form tumor spheres in vitro and to i

120 tion of SOX5/6/21 dramatically increased the capacity of these cells to form glioma-like tumors in an

121 clude that herbivorous insects may limit the capacity of forests to function as sinks for anthropogen

122 Soil health has been defined as the capacity of soil to function as a vital living system to

123 lier conclusions from ex vivo work about the capacity of cortical neurons to generate precise dischar

124 Oxidative burden is used to describe the capacity of PM2.5 to generate reactive oxygen species in

125 h emergence of intermediate progenitors; and capacity of single NSCs to generate the correct number a

126 fter orofacial inflammation and increase the capacity of TG neurons to generate OLAMs.

127 sing electron microscopy, we demonstrate the capacity of these proteins to generate ordered one-dimen

128 ngraftment levels, associated with a reduced capacity of the transplanted cells to home to the bone m

129 The capacity of ACOT7 to hydrolyze long-chain acyl-CoA ester

130 esults demonstrate the high representational capacity of multivariate statistical methods to identify

131 munity against murine norovirus requires the capacity of IECs to respond to IFN-lambda.

132 The capacity of 10 to impair Pgp transporter is also discuss

133 The capacity of risk factor confluence to improve IHD risk p

134 roachment may enhance carbon storage and the capacity of a wetland to increase surface elevation in r

135 deficient induction of IL-1RI, reducing the capacity of IL-1beta to increase COX-2 and mPGES-1 expre

136 ococcal pneumonia is in part mediated by the capacity of welding fumes to increase PAFR-dependent pne

137 of their development, we discovered that the capacity of a PROTAC to induce degradation involves more

138 often called prion-like, which refers to the capacity of an assembled protein to induce the same abno

139 Here we examined the capacity of glucolipotoxicity to induce free cholesterol

140 e both the MyD88 and TRIF pathways, (ii) the capacity of Tat to induce TIRAP/MAL degradation, (iii) t

141 We assessed the capacity of these vaccines to induce functional HCV-spec

142 The capacity of two Micromonospora strains to infect legumes

143 reclinical published data with regard to the capacity of MSCs to influence fibrotic response to liver

144 human T cells by nucleofection abolished the capacity of ILT3.Fc to inhibit CD4(+) Th cell proliferat

145 The capacity of peach DMSO extracts to inhibit Candida albic

146 We report herein the capacity of sugar-based peptidomimetics to inhibit both

147 In the 1970s, the capacity of T cells to inhibit immunity and those from t

148 Moreover, the capacity of the tVTA to inhibit, but not disinhibit, DA

149 the OVA-specific response was not due to the capacity of uricase to inhibit the early steps of OVA up

150 regulation mechanism, and could explain the capacity of the complex to integrate multiple regulatory

151 s on the other, which together determine the capacity of IgG to interact in a cell-type-specific mann

152 Furthermore, the capacity of M-Tha to interact with RelAp43 was shown to

153 ranular layers, and they indicate comparable capacities of both stimulation methods to isolate thalam

154 The resistance was linked to an improved capacity of E11 to bind to its host cells, which was fur

155 This paralyzes the capacity of neutrophils and macrophages to kill bacteria

156 its cortical mechanisms and will enhance the capacity of computational models to learn from visual ex

157 To explore the capacity of mice and humans to learn tactile sequences,

158 onal and structural plasticity relied on the capacity of transplanted NPCs to localize in the peri-is

159 efoldedin vitrowith pigments showed that the capacity of responding to low pH by decreasing the fluor

160 The capacity of a habitat to maintain growth will be crucial

161 It is now clear that the capacity of cells to maintain proteostasis undergoes a d

162 Together, our findings reveal an unexpected capacity of primary cells to maintain transcriptome inte

163 n bioorthogonal catalysis are increasing the capacity of researchers to manipulate the fate of molecu

164 etic lineages and establish an unanticipated capacity of megakaryocytes to mediate IL-1-driven system

165 The capacity of these CBS domains to mediate the catalytic a

166 It is not clear how WNT augments the capacity of osteoblast progenitors to meet the increased

167 for biological functions that may affect the capacity of hatchery-born smolts to migrate successfully

168 rce will have an increasing influence on the capacity of plants to mitigate human greenhouse gas emis

169 y predicted by climate change will alter the capacity of biocrust-forming mosses to modulate multiple

170 However, the capacity of IFNalpha/beta to modulate human activated au

171 Our results reveal an unexpected capacity of local auxin metabolism to modulate the homeo

172 The capacity of NAMI-A to modulate the relationship establis

173 Lack of IL-4 responsiveness attenuates the capacity of CD8(+) T cells to mount a robust response to

174 We estimate that the capacity of animals to move nutrients away from concentr

175 re largely normal, highlighting a remarkable capacity of olfactory circuits to normalize sensory inpu

176 This work establishes that Fhod shares the capacity of other formins to nucleate and bundle actin f

177 hotovoltaic is well matched to the operating capacity of the electrolysers to optimize the system eff

178 The capacity of ECMs to orchestrate functional muscle tissue

179 In the current study, the capacity of mouse platelets to participate in host defen

180 One potential explanation is the lack of capacity of this agent to penetrate the central nervous

181 Here, we explored the capacity of Pol epsilon to perform strand displacement s

182 The capacity of the platform to perform multiplexed measurem

183 luted human serum we further investigate the capacity of the proposed technique to perform specific t

184 s known in P. putida but also recognizes the capacity of this bacterium to perform difficult redox re

185 ting that mesalamine aids in diminishing the capacity of bacteria to persist within chronically infla

186 erate change in seasonality may outstrip the capacity of greater bamboo lemurs to persist on their me

187 r to daughter cells, and favors the response capacity of the latter to physiological signals and envi

188 c basis for cmvIL-10 function, including the capacity of this viral cytokine to potentially amplify i

189 pact ofCtCBM3a is in sharp contrast with the capacity of this binding module to potentiate the activi

190 The capacity of in vitro assays to predict As RBA was demons

191 The capacity of renal DCs to present antigen was examined by

192 related to sexual outcomes, and outline the capacity of vessel-sparing radiotherapy to preserve sexu

193 those most likely to explain the remarkable capacity of the brain to process information and govern

194 ion of CD8alpha(+) DC homeostasis and in the capacity of these cells to process and present antigens

195 human institution that recurs because of the capacity of cultural evolution to produce practices adap

196 ntiviral host responses that is based on the capacity of HAdV3 to produce subviral penton-dodecahedra

197 eral blood CD8(+) T-cell function and/or the capacity of individuals to produce IL-10 may represent b

198 echanistically, loss of Ptpn22 increases the capacity of T cells to produce IL-2, which overcomes TGF

199 Understanding of the capacity of the natural world to produce secondary metab

200 Enhancing the capacity of CD8(+) T cells to promote resolution or incr

201 a provide unique insights into the selective capacity of receptor ligands to promote and/or stabilize

202 of this targeted migration was traced to the capacity of TGF-beta1 to promote CCR7/CCL21-mediated cro

203 To study the capacity of the lipid-ligand to promote sensitization to

204 Cell type specification relies on the capacity of undifferentiated cells to properly respond t

205 The capacity of licensed vaccines to protect the ocular surf

206 re, and burning and thereby might reduce the capacity of landscapes to provide archives of climate ch

207 The capacity of pediatric hospitals to provide treatment to

208 This mechanism utilizes the innate capacity of surrounding neuronal networks to provide pro

209 The capacity of vector insect surveillance to provide estima

210 The doing lessons involve improving the capacity of the research community to put its understand

211 ) Reduced KCC2 levels, however, restrict the capacity of RT neurons to rapidly extrude Cl(-) followin

212 eneration, and they highlight the remarkable capacity of CNS neurons to re-establish accurate circuit

213 nelrhodopsin-2 expressing mice to assess the capacity of the cortex to re-establish motor output long

214 cal and clinical evidence indicates that the capacity of immunogenic cell death to (re-)activate an a

215 SBVp32 virulence is associated with the capacity of this virus to reach high titers in the brain

216 organism during its evolution highlights the capacity of some pathogens to readily expand into new ho

217 discuss the mechanisms whereby RT alters the capacity of the immune system to recognize and eliminate

218 re, we harnessed the endogenous regenerative capacity of the zebrafish retina to reconstruct the circ

219 Although the capacity of the liver to recover its size after resectio

220 e change has led to a decline of 1/3 in the capacity of these disturbed forests to recover and recap

221 ng of class II transactivator can reduce the capacity of human endothelial cells to recruit and activ

222 up size, and acyl chain length, modulate the capacity of membrane curvature to recruit lipidated prot

223 ntent was positively correlated (p<0.001) to capacity of coffee to reduce nitric oxide and scavenge F

224 ks the onset of a rapid deterioration in the capacity of the GICs firn to refreeze meltwater.

225 These findings demonstrate the remarkable capacity of adult neurons to regenerate functional circu

226 The results highlight the capacity of lipids to regulate the conformation of membr

227 to accurately detect aberrant mRNAs and the capacity of long 3'UTRs to regulate gene expression.

228 The capacity of Perm1 to regulate muscle mitochondrial conte

229 distinctive feature of sepsis is the reduced capacity of leukocytes to release proinflammatory cytoki

230 riminate against ribonucleotides, and by the capacity of repair mechanisms to remove incorporated rib

231 rogramming of progenitors, but the intrinsic capacity of the developing brain to replenish lost cells

232 jagged-2 was dispensable for maintaining the capacity of HSPCs to repopulate under steady-state condi

233 o examine how information format affects the capacity of neurons to represent stimuli, we measured th

234 titrait eco-evolutionary model to assess the capacity of these processes to reproduce 74 y of histori

235 ucagon deficiency did not impair the natural capacity of alpha-cells to reprogram into insulin produc

236 The capacity of mosquitoes to resist insecticides threatens

237 )C]DHA can be used, therefore, to assess the capacity of tumor cells to resist oxidative stress in vi

238 phase NER proficiency is correlated with the capacity of individual mutants to respond to replicative

239 Here, we show that the capacity of presynaptic cholinergic synapses to respond

240 e naive CD8 T cell repertoire, affecting the capacity of the host to respond to new infections.

241 n and inversely correlated with the residual capacity of the immune system to respond to new infectio

242 on near the lesion epicenter and rescued the capacity of these cells to restore function.

243 ce IDO1-mediated suppression and the reduced capacity of RASF to restrict Th cell proliferation throu

244 n, inhabiting the same niche, may affect the capacity of the mucus barrier to retain commensal E. col

245 Thus, the capacity of NK cells to secrete IL-10 plays a unique rol

246 lasma creatinine concentration and a reduced capacity of the kidney to secrete anionic drugs (furosem

247 Self-righting, the capacity of an animal to self-turn after falling on its

248 Further motivated by the well-established capacity of PDT photosensitizers to serve as tumour-sele

249 llogeneic (allo-)MSCs are immunoevasive, the capacity of CSCs to similarly elude the immune system re

250 an be partly explained by differences in the capacity of models to simulate gross growth (both birth

251 ware package for scoring and summarising the capacity of gene ontology features to simultaneously cla

252 ial for additional soil C sequestration, the capacity of land ecosystems to slow the rise in atmosphe

253 Fe(II) oxidation through O2 production, the capacity of their cell surfaces to sorb iron, and the in

254 his provides a potential explanation for the capacity of this asexual snail to spread by adaptive evo

255 degranulation in real time by exploiting the capacity of fluorochrome-labeled avidin to stain degranu

256 cells undergoing peripheral deletion is the capacity of the latter to still signal through MAPKs upo

257 The capacity of DC to stimulate allogenic splenocyte prolife

258 that reduce HVEM expression could alter the capacity of FL B cells to stimulate allogeneic T-cell re

259 Additional assays revealed deficits in the capacity of GIT1-R283W to stimulate PAK phosphorylation

260 We sought to determine the capacity of RSV infection to stimulate group 2 innate ly

261 impact of an acquired genetic lesion on the capacity of tumor cells to stimulate allogeneic T-cell i

262 Soil pH regulates the capacity of soils to store and supply nutrients, and thu

263 Heightened cellular activation promotes the capacity of CD4 T cells to support productive HIV replic

264 and neurogenesis, highlighting the intrinsic capacity of non-neurogenic vasculature to support stem c

265 IL-4R signaling impaired the capacity of Treg cells to suppress mast cell activation

266 We found that the capacity of coral recruits to survive under warmer tempe

267 ection in resting CD4 T cells resides in the capacity of these cells to survive the early steps of HI

268 impact reef carbonate budgets, and thus the capacity of reefs to sustain vertical growth under risin

269 eater expansion and persistence in vivo, the capacity of such cells to sustain effector functions wit

270 This led to controversies about the capacity of liver cells to switch their fate.

271 The impaired capacity of skeletal muscle to switch between the oxidat

272 d stress-induced behavioral pathology to the capacity of PFC to synchronize amygdala and VTA activity

273 o ofloxacin is inversely correlated with the capacity of non-growing cells to synthesize protein.

274 thus providing a mechanism for the enhanced capacity of P. aeruginosa to target bacteria that elabor

275 he signaling components that account for the capacity of progesterone to target specific subsets of m

276 tein, and properties of sigma1 influence the capacity of reovirus to target specific host tissues and

277 The photoprotective capacity of kleptoplasts was compared to that observed i

278 onstraints on phenotypic variation limit the capacity of organisms to adapt to the multiple selection

279 tibodies specifically affecting the adhesive capacity of S. pneumoniae led to the identification of t

280 Water holding and fat absorption capacities of FPI were similar to those of the above men

281 onment, namely the host diet, influences the capacity of an organism to tolerate and resist infection

282 dent to explore the potential to augment the capacity of reef organisms to tolerate stress and to fac

283 nous beta activity, but not primarily by the capacity of theta activity to track the syllabic rhythm.

284 ls, suggesting an explanation for the latent capacity of these cells to transdifferentiate into hair

285 Additionally, the uveitogenic capacity of Th17 cells to transfer EAU was abrogated by

286 ation of rRNA plays an important role in the capacity of the parasite to transit between the insect m

287 c ionophore activity was demonstrated as the capacity of polyphenols to transport zinc cations across

288 ion among stormflow events suggests that the capacity of these systems to trap and retain solids and

289 To enhance the capacity of the NYVAC vector to trigger broad humoral re

290 ggesting that age influences the tumorigenic capacity of BMCs in response to tumor-associated signals

291 g in the central channel correlates with the capacity of motif V to twist and order in the SaPI-induc

292 Finally, we demonstrate the capacity of this approach to uncover additional new info

293 This trial shows the capacity of helminths to up-regulate inhibitory molecule

294 This capacity of cmvIL-10 to upregulate hIL-10 represents a m

295 ucosamine, or pyruvate) revealed contrasting capacity of bacterioplankton to utilize specific carbon

296 by primary glia cell coculture abolished the capacity of metastatic cells to utilize extracellular gl

297 ogical disorders, to which a decrease in the capacity of the brain to utilize glucose has been linked

298 During the development of heart failure, the capacity of the heart to utilize fatty acids, the chief

299 evolutionary process shows that the genetic capacity of an organism to vary traits can qualitatively

300 ry examination revealed the specific binding capacity of fluorescein isothiocyanate-RamAb to VEGFR-2,