ライフサイエンスコーパス: capsulatum

1 longed the survival of mice infected with H. capsulatum.

2 mperature-regulated morphologic switch in H. capsulatum.

3 ogens Coccidioides posadasii and Histoplasma capsulatum.

4 nity in an Ag-specific manner to Histoplasma capsulatum.

5 ogenicity in Blastomyces dermatitidis and H. capsulatum.

6 the genetics and regulatory mechanisms of A. capsulatum.

7 utes to host resistance to infection with H. capsulatum.

8 the lungs of mice infected with Histoplasma capsulatum.

9 a but not morphologically consistent with H. capsulatum.

10 ritical element of protective immunity to H. capsulatum.

11 ed host resistance to the fungus Histoplasma capsulatum.

12 is by IFN-gamma and effective handling of H. capsulatum.

13 e agents in host defense against Histoplasma capsulatum.

14 rotective and memory immunity to Histoplasma capsulatum.

15 ulfur metabolism influences morphology in H. capsulatum.

16 fection with the fungal pathogen Histoplasma capsulatum.

17 ion of the worldwide presence of Histoplasma capsulatum.

18 in vivo, mice were infected with Histoplasma capsulatum.

19 3) of heat-shock protein 60 from Histoplasma capsulatum.

20 ungs of naive mice infected with Histoplasma capsulatum.

21 c oxide reductase (P450nor) from Histoplasma capsulatum.

22 or 6 organisms than with class 2 Histoplasma capsulatum.

23 e immunogen against pulmonary exposure to H. capsulatum.

24 wo yeast phase-specific genes in Histoplasma capsulatum.

25 hock protein 60 from the fungus, Histoplasma capsulatum.

26 e designed to amplify the Hcp100 locus of H. capsulatum.

27 mary infection with the pathogen Histoplasma capsulatum.

28 ined abundant yeast forms consistent with H. capsulatum.

29 hree families of siderophores excreted by H. capsulatum.

30 mation on the hydroxamate siderophores of H. capsulatum.

31 ary and secondary infection with Histoplasma capsulatum.

32 al for functional expression of a gene in H. capsulatum.

33 by transformation of an HAG1 plasmid into H. capsulatum.

34 studies of the dimorphic fungus Histoplasma capsulatum.

35 st Mycobacterium tuberculosis or Histoplasma capsulatum.

36 His CSF culture also was positive for H capsulatum.

37 n CCR5(-/)(-) mice infected with Histoplasma capsulatum.

38 with the intracellular pathogen Histoplasma capsulatum.

39 erevisiae, Candida albicans, and Histoplasma capsulatum.

40 lates the yeast to mycelial transition in H. capsulatum.

41 100% specificity and 94% sensitivity for H. capsulatum.

42 tomyces dermatitidis and also in Histoplasma capsulatum.

43 fection with the fungal pathogen Histoplasma capsulatum.

44 latent infections of the fungus Histoplasma capsulatum.

45 nfection by the dimorphic fungus Histoplasma capsulatum.

46 antibody (MAb) raised against a Histoplasma capsulatum 80-kDa hsp showed cross-reactivity to the pur

47 s an extracellular pathogen, and Histoplasma capsulatum a facultative intracellular pathogen.

48 Histoplasma capsulatum, a fungal pathogen of humans, switches from a

49 se model of acute infection with Histoplasma capsulatum, a major human pathogenic fungus.

50 ost abundant protein secreted by Histoplasma capsulatum, a pathogenic fungus that causes histoplasmos

51 We describe a case in which the Histoplasma capsulatum AccuProbe test displayed cross-reactivity wit

52 demonstrated the ability of the Histoplasma capsulatum AccuProbe to accurately identify this organis

53 t immunoglobulin Gs (IgGs) to Hsp60 cause H. capsulatum aggregation dependent on the (i) concentratio

54 ted a high mortality after infection with H. capsulatum, although TNFR1-/- mice were more susceptible

55 morphologic switch, which is exhibited by H. capsulatum and a group of evolutionarily related fungal

56 e the predominant infectious particle for H. capsulatum and are the first cell type encountered by th

57 tent antifungal activity against Histoplasma capsulatum and Cryptococcus neoformans by distinct mecha

58 s built with genomic elements of Histoplasma capsulatum and ESTs of Paracoccidioides brasiliensis tha

59 Tissues from mice infected with H. capsulatum and from biopsy specimens from a patient with

60 e suggests a direct link between Histoplasma capsulatum and presumed ocular histoplasmosis syndrome,

61 oth surface localized in the cell wall of H. capsulatum and released into the culture medium.

62 pecies, Cryptococcus neoformans, Histoplasma capsulatum, and Blastomyces dermatitidis from blood cult

63 America (Coccidioides posadasii, Histoplasma capsulatum, and Blastomyces dermatitidis), have soared r

64 duced resistance against B. dermatitidis, H. capsulatum, and C. posadasii.

65 on ancestor, Wor1 in C. albicans, Ryp1 in H. capsulatum, and Mit1 in S. cerevisiae are transcriptiona

66 gs of C57BL/6 mice infected with Histoplasma capsulatum, and the elimination of these cells impairs p

67 the detection of Histoplasma capsulatum var. capsulatum antigens may provide a more practical approac

68 Blastomyces dermatitidis and Histoplasma capsulatum are dimorphic fungi that often cause self-lim

69 ved methods for the detection of Histoplasma capsulatum are needed in regions with limited resources

70 phic fungal pathogens, including Histoplasma capsulatum, are soil fungi that undergo dramatic changes

71 The success of Histoplasma capsulatum as an intracellular pathogen depends complete

72 dimorphic probe hybridized with DNA from H. capsulatum, B. dermatitidis, C. immitis, P. brasiliensis

73 Specific probes for H. capsulatum, B. dermatitidis, C. immitis, P. brasiliensis

74 In H. capsulatum BAD1 transformants, yeast phase-specific expr

75 DPPIV homologs (HcDPPIVA and HcDPPIVB) in H. capsulatum based on a homology search with Aspergillus f

76 F-1alpha in the host response to Histoplasma capsulatum because granulomas induced by this pathogenic

77 A, were used to amplify DNA from Histoplasma capsulatum, Blastomyces dermatitidis, Coccidioides immit

78 intracellular pathogens such as Histoplasma capsulatum, but its mode of action remains elusive.

79 ous IL-4 modulates protective immunity to H. capsulatum by delaying clearance of the organism but doe

80 ts were generated in a virulent strain of H. capsulatum by optimization of Agrobacterium tumefaciens-

81 Chloroquine inhibits growth of H. capsulatum by pH-dependent iron deprivation, whereas it

82 Histoplasma capsulatum can efficiently survive within macrophages, f

83 However, H. capsulatum can establish persistent infections, indicati

84 Except with Histoplasma capsulatum, chocolate agar incubated for only 3 days pro

85 ht, with the notable distinction that the H. capsulatum circuit responds to temperature.

86 n H protein expression levels between the H. capsulatum classes, with a correlation between secreted

87 t episodes, the isolated fungus (Histoplasma capsulatum, Coccidioides immitis/posadasii, Fusarium oxy

88 The endemic fungi Histoplasma capsulatum, Coccidioides spp, Blastomyces dermatitidis,

89 a Mycobacterium haemophilum and Histoplasma capsulatum coinfection occurring 21 years after a living

90 for B. dermatitidis and 100% and 73% for H. capsulatum compared with the results for culture.

91 r fusions analysed in B. dermatitidis and H. capsulatum confirmed that BAD1 is transcriptionally regu

92 These findings indicate that H. capsulatum conidia and yeast can produce melanin or mela

93 uced in macrophages during infection with H. capsulatum conidia but not H. capsulatum yeast cells.

94 H. capsulatum conidia were also cytotoxic to amoebae.

95 on of WGA-Fc fully protected mice against H. capsulatum, correlating with a reduction in lung, spleen

96 as concordance of four gene genealogies, H. capsulatum could be considered to harbor six species ins

97 Substrate gels with H. capsulatum culture supernatants revealed beta-glucosidas

98 immunization with H antigen from Histoplasma capsulatum did not protect mice against an intravenous c

99 Because H. capsulatum displays a considerable array of virulence me

100 The fungus Histoplasma capsulatum displays an Hsp60 on its cell surface that is

101 Finally, H. capsulatum displays morphotype-specific expression of se

102 um isolates representing the three varieties capsulatum, duboisii, and farciminosum was evaluated usi

103 icantly impacted pathogenic mechanisms of H. capsulatum during macrophage infection, and the effect w

104 secreted proteolytic activity in Histoplasma capsulatum effective toward DppIV-specific substrates.

105 , cathepsin G, and BPI are the major anti-H. capsulatum effector molecules in the azurophil granules

106 The adverse effects of IL-4 on H. capsulatum elimination were not observed during the earl

107 The YPS3 gene of Histoplasma capsulatum encodes a protein that is both surface locali

108 We report a case of Histoplasma capsulatum endocarditis in which Histoplasma antigen ass

109 The pathogenic fungus Histoplasma capsulatum escapes innate immune defenses and colonizes

110 The fungal pathogen Histoplasma capsulatum evades the innate and adaptive immune respons

111 A "dimorphic" fungus, H. capsulatum exists as a saprophytic mold in soil and conv

112 H. capsulatum expresses several iron acquisition mechanisms

113 Here, we report H. capsulatum ferric reduction activities in whole yeast ce

114 for the detection of B. dermatitidis and H. capsulatum from culture isolates and directly from clini

115 ect and differentiate B. dermatitidis and H. capsulatum from culture isolates and directly from clini

116 T cells (Tregs) using a model of Histoplasma capsulatum fungal infection.

117 esenting 10-fold coverage of the Histoplasma capsulatum G217B genome was used to construct a restrict

118 In a screen to identify H. capsulatum genes required for lysis of bone marrow-deriv

119 Here, we detail mapping the Histoplasma capsulatum genome comprehensively in fosmids, resulting

120 ighteen of 19 blood cultures positive for H. capsulatum grew in both IS and MFL, although the time to

121 atum, (iv) South American H. capsulatum var. capsulatum group A, (v) South American H. capsulatum var

122 oup A, (v) South American H. capsulatum var. capsulatum group B, and (vi) H. capsulatum var. duboisii

123 Wild-type H. capsulatum grows as filaments at room temperature and as

124 The human fungal pathogen Histoplasma capsulatum grows in a sporulating filamentous form in th

125 ine biosynthetic pathway is essential for H. capsulatum growth and virulence.

126 lony-stimulating factor (GM-CSF), inhibit H. capsulatum growth in macrophages.

127 Interestingly, H. capsulatum growth was restricted in mice lacking the typ

128 The Histoplasma capsulatum H antigen is a major secreted glycoprotein of

129 intracellular pathogenic fungus Histoplasma capsulatum has increased dramatically.

130 l pathogens Candida albicans and Histoplasma capsulatum have been reported to protect against the oxi

131 Ten cases of Histoplasma capsulatum (HC) infection were reported: 9 associated wi

132 Histoplasma capsulatum (Hc) is a facultative intracellular fungal pa

133 Histoplasma capsulatum (Hc) is a facultative intracellular fungus th

134 Histoplasma capsulatum (Hc) is a facultative, intracellular parasite

135 Histoplasma capsulatum (Hc) is a pathogenic fungus that replicates i

136 econdary infection by the fungus Histoplasma capsulatum (HC) is multifactorial, requiring cells of th

137 Histoplasma capsulatum (Hc) maintains a phagosomal pH of about 6.5.

138 he intracellular fungal pathogen Histoplasma capsulatum (Hc) resides in mammalian macrophages and cau

139 Cryptococcus neoformans (CN) and Histoplasma capsulatum (HC) to external gamma-radiation and to the o

140 Histoplasma capsulatum (Hc), is a facultative intracellular fungus t

141 se against the pathogenic fungus Histoplasma capsulatum (Hc).

142 with observations in other organisms, the H. capsulatum hcl1 mutant was unable to grow on leucine as

143 cus neoformans (cryptococcosis), Histoplasma capsulatum (histoplasmosis), and Talaromyces (Penicilliu

144 fied an insertion mutation disrupting the H. capsulatum homolog of 3-hydroxy-methylglutaryl coenzyme

145 ) isotype monoclonal antibodies (MAbs) to H. capsulatum Hsp60.

146 i) class 1 North American H. capsulatum var. capsulatum, (ii) class 2 North American H. capsulatum va

147 i) class 2 North American H. capsulatum var. capsulatum, (iii) Central American H. capsulatum var. ca

148 his drove IL-10 production in response to H. capsulatum IL-10 inhibited Mvarphi control of fungal gro

149 Treatment of naive and H. capsulatum-immune mice with caspase inhibitors decreased

150 n (BPI) also mediated fungistasis against H. capsulatum in a concentration-dependent manner.

151 fungal isolates tested and also detected H. capsulatum in clinical specimens from three patients tha

152 A real-time PCR assay to detect Histoplasma capsulatum in formalin-fixed, paraffin-embedded (FFPE) t

153 clearance of the fungal pathogen Histoplasma capsulatum in mice lacking the chemokine receptor CCR2.

154 esponse is required for full virulence of H. capsulatum in mice.

155 used to expedite culture confirmation of H. capsulatum in regions in which PDH is endemic.

156 V-ATPase function in the pathogenicity of H. capsulatum, in iron homeostasis and in fungal dimorphism

157 The production of H. capsulatum-induced interferon-gamma and TNF-alpha was as

158 Histoplasma capsulatum induces a cell-mediated immune response in lu

159 at shock protein 60 (Hsp60) from Histoplasma capsulatum induces a protective immune response in mice.

160 ation of excess interleukin-4 in lungs of H. capsulatum-infected CCR2(-/-) mice is at least partially

161 H. capsulatum-infected CCR2(-/-) mice manifested defects in

162 Apoptosis was diminished in H. capsulatum-infected gld/gld and TNF-alpha-deficient mice

163 ations in the metal homeostasis of murine H. capsulatum-infected macrophages that were exposed to act

164 Rising rates of Histoplasma capsulatum infection are an emerging problem among the r

165 hat CCR5 controls the outcome of Histoplasma capsulatum infection by dictating thymic and lymph node

166 erleukin (IL)-17 and IL-23 on immunity to H. capsulatum infection in mice.

167 n vivo, Zn supplementation and subsequent H. capsulatum infection supressed MHCII on DCs, enhanced PD

168 ce that received methamphetamine prior to H. capsulatum infection were immunologically impaired, with

169 specifically limits iron during Histoplasma capsulatum infection, and fungal acquisition of iron is

170 aive and immune mice during the course of H. capsulatum infection.

171 of Tregs in the lungs prior to and during H. capsulatum infection.

172 he balance between Treg and Th17 cells in H. capsulatum infection.

173 ns-mediated mutagenesis, and screened for H. capsulatum insertional mutants that were unable to survi

174 ce were infected by injection of Histoplasma capsulatum into the subarachnoid space.

175 Histoplasma capsulatum is a dimorphic fungal pathogen that survives

176 Histoplasma capsulatum is a dimorphic fungus that causes respiratory

177 Histoplasma capsulatum is a dimorphic fungus that is endemic in the

178 Histoplasma capsulatum is a fungal pathogen that causes respiratory

179 Histoplasma capsulatum is a fungal pathogen that requires the induct

180 Histoplasma capsulatum is a fungal respiratory pathogen that survive

181 Histoplasma capsulatum is a respiratory pathogen that infects phagoc

182 Histoplasma capsulatum is a significant respiratory and systemic fun

183 Histoplasma capsulatum is a successful intracellular pathogen of mam

184 Acidobacterium capsulatum is an acid-tolerant, encapsulated, Gram-negat

185 Histoplasma capsulatum is an effective intracellular parasite of mac

186 Histoplasma capsulatum is an infrequent but serious cause of endocar

187 the immune response during infection with H. capsulatum is controlled via mechanisms independent of t

188 importance to its success or failure, and H. capsulatum is good at finding or making the right enviro

189 cteria; however, the time to detection of H. capsulatum is increased.

190 l feature of the fungal pathogen Histoplasma capsulatum is its ability to shift from a mycelial phase

191 Histoplasma capsulatum is the best-studied of the primary pathogens

192 esis of the respiratory pathogen Histoplasma capsulatum is the conversion from the mold form (found i

193 Histoplasma capsulatum is the most common cause of fungal respirator

194 The yeast phase of Histoplasma capsulatum is the virulent form of this thermally dimorp

195 sition in pathogenic organisms, including H. capsulatum, is a highly regulated process.

196 psulatum that correctly identified the 34 H. capsulatum isolates in a battery of 107 fungal isolates

197 eny of 46 geographically diverse Histoplasma capsulatum isolates representing the three varieties cap

198 m, (iii) Central American H. capsulatum var. capsulatum, (iv) South American H. capsulatum var. capsu

199 The zoopathogenic fungus Histoplasma capsulatum, like other eukaryotic aerobic microorganisms

200 cate we have cloned the gene encoding the A. capsulatum major sigma factor and the gene product is ac

201 gap, we identified the gene encoding the A. capsulatum major sigma factor, rpoD, which encodes a 597

202 nsidered a resident of the phagolysosome, H. capsulatum may also reside in a modified phagosome witho

203 lu) and amphotericin B (AmB) for Histoplasma capsulatum meningitis, MICs were determined for 10 clini

204 The fungal pathogen Histoplasma capsulatum minimizes detection of beta-glucan by host ce

205 hich the primary fungal pathogen Histoplasma capsulatum multiplies and disseminates from the lung to

206 H. capsulatum must compete with the host to acquire the ess

207 this hypothesis has not been tested since H. capsulatum mutants that experience decreased phagosomal

208 Growth of H. capsulatum mycelia in chemically defined minimal medium

209 nly (three Candida albicans, one Histoplasma capsulatum, one Candida glabrata, and one Fusarium speci

210 A, they did not necessarily correspond to H. capsulatum open reading frames.

211 with heat shock protein 60 from Histoplasma capsulatum or a polypeptide from the protein designated

212 t shock protein 60 (rHsp60) from Histoplasma capsulatum or a region of the protein designated fragmen

213 F bottle did not recover M. tuberculosis, H. capsulatum, or C. neoformans isolates.

214 the site preference measured for purified H. capsulatum P450nor was not constant, increasing from app

215 , IgG1 and IgG2a MAbs to Hsp60 can modify H. capsulatum pathogenesis in part by altering the intracel

216 mic mycosis caused by the fungus Histoplasma capsulatum, primarily affects immune-suppressed patients

217 e used against C. immitis DNA and for the H. capsulatum probe used against Candida albicans DNA.

218 fungal pathogen Histoplasma capsulatum var. capsulatum produced melanin or melanin-like compounds in

219 The fungus, Histoplasma capsulatum, produces a persistent infection.

220 of cells from mice immunized with either H. capsulatum recombinant Hsp70 or bovine serum albumin.

221 dicate the importance of Hcl1 function in H. capsulatum replication in the harsh growth environment o

222 ial effector nitric oxide (*NO) restricts H. capsulatum replication.

223 In response to excess iron, H. capsulatum represses transcription of genes involved in

224 Host defenses against Histoplasma capsulatum require the action of several cytokines.

225 The pathogenic fungus Histoplasma capsulatum requires iron for its survival during macroph

226 on against the pathogenic fungus Histoplasma capsulatum requires Th1 cytokines.

227 ehydrogenase genes of B. dermatitidis and H. capsulatum, respectively.

228 To understand how H. capsulatum responds to RNS, we determined the transcript

229 ed beta-glucosidase activities from three H. capsulatum restriction fragment length polymorphism (RFL

230 A. capsulatum RpoD restored normal growth to E. coli strain

231 nd calcium and its prevalence as Histoplasma capsulatum's most abundant secreted protein.

232 tical disease occurring in the absence of H. capsulatum seropositivity.

233 Histoplasma capsulatum should be considered in the differential diag

234 The H. capsulatum siderophore dimerum acid and the structurally

235 , the capacity of IgG MAbs to agglutinate H. capsulatum significantly impacted pathogenic mechanisms

236 ' sera of a 69- to 70-kDa H. capsulatum var. capsulatum-specific antigen which appears to be useful i

237 eneral DNA binding proteins from Histoplasma capsulatum strain G217B.

238 n and is also expressed differentially in H. capsulatum strains of different virulence levels.

239 erated monoclonal antibodies (MAbs) to an H. capsulatum surface-expressed heat shock protein of 60 kD

240 ere we show that a 250-fold difference in H. capsulatum susceptibility between inbred mouse strains i

241 or the dimorphic fungal pathogen Histoplasma capsulatum, susceptibility to echinocandins differs for

242 e complication of infection with Histoplasma capsulatum that can lead to obstruction of pulmonary and

243 nce of infection with the fungus Histoplasma capsulatum that can lead to occlusion of large pulmonary

244 selected for, or induced, a phenotype of H. capsulatum that caused a persistent murine lung infectio

245 l-time LightCycler PCR assay for Histoplasma capsulatum that correctly identified the 34 H. capsulatu

246 al in response to a sublethal inoculum of H. capsulatum The absence of myeloid HIF-1alpha did not alt

247 revealed an important mechanism by which H. capsulatum thwarts the host immune system.

248 determined the transcriptional profile of H. capsulatum to *NO-generating compounds using a shotgun g

249 sure of an avirulent laboratory strain of H. capsulatum to A. castellanii selected for, or induced, a

250 Although the ability of H. capsulatum to prevent acidification of the macrophage ph

251 was sufficient to increase resistance of H. capsulatum to RNS in culture.

252 patterns ranging from circular (Histoplasma capsulatum) to punctate (Cryptococcus neoformans) to lab

253 survive within macrophages, facilitating H. capsulatum translocation from the lung into the lymphati

254 Detection of the Histoplasma capsulatum urinary antigen (UAg) is among the most sensi

255 H. capsulatum uses different host receptors for binding to

256 We propose that H. capsulatum uses the pathways identified here to cope wit

257 we designed a strategy to disrupt CBP1 in H. capsulatum using a telomeric linear plasmid and a two-st

258 ed use, whereas the detection of Histoplasma capsulatum var. capsulatum antigens may provide a more p

259 atum var. capsulatum, (iv) South American H. capsulatum var. capsulatum group A, (v) South American H

260 r. capsulatum group A, (v) South American H. capsulatum var. capsulatum group B, and (vi) H. capsulat

261 rmally dimorphic fungal pathogen Histoplasma capsulatum var. capsulatum produced melanin or melanin-l

262 ed six clades: (i) class 1 North American H. capsulatum var. capsulatum, (ii) class 2 North American

263 . capsulatum, (ii) class 2 North American H. capsulatum var. capsulatum, (iii) Central American H. ca

264 m var. capsulatum, (iii) Central American H. capsulatum var. capsulatum, (iv) South American H. capsu

265 tion in patients' sera of a 69- to 70-kDa H. capsulatum var. capsulatum-specific antigen which appear

266 sulatum var. capsulatum group B, and (vi) H. capsulatum var. duboisii.

267 The presence of H. capsulatum var. farciminosum DNA was confirmed by sequen

268 first reports of the direct detection of H. capsulatum var. farciminosum in equine blood and at high

269 he 29 horses with suspected cases of EZL, H. capsulatum var. farciminosum was confirmed by extraction

270 Histoplasma capsulatum var. farciminosum, the causative agent of epi

271 nce for the existence of two subgroups of H. capsulatum var. farciminosum.

272 acil auxotrophy due to a ura5 mutation on H. capsulatum virulence in both cell culture and whole-anim

273 of the dimorphic fungal pathogen Histoplasma capsulatum was first described over 40 years ago.

274 es and alveolar macrophages infected with H. capsulatum was inhibited by the addition of physiologic

275 Intracellular proliferation of H. capsulatum was measured in alveolar macrophages and peri

276 r intranasal exposure of mice to Histoplasma capsulatum was necessary for control of primary or secon

277 Consequently, H. capsulatum was selectively deprived of Zn, thereby halti

278 To identify phase-regulated genes of H. capsulatum, we carried out expression analyses by using

279 ants of Francisella novicida and Histoplasma capsulatum, we confirmed the applicability of these host

280 tidis, Sporothrix schenckii, and Histoplasma capsulatum were each ingested by amoebae and macrophages

281 of rRNA genes of 24 isolates of Histoplasma capsulatum were examined.

282 Two isolates of Histoplasma capsulatum were recovered from the Isolator tube only.

283 more diverged pathogenic fungus, Histoplasma capsulatum, were sequenced and compared with those of 13

284 ure-responsive transcriptional network in H. capsulatum, which switches from a filamentous form in th

285 eminated Coccidioides immitis or Histoplasma capsulatum with heterozygous missense mutations in the S

286 of infected mice, aberrant processing of H. capsulatum within macrophages, and immobilization of MAC

287 portant for survival and proliferation of H. capsulatum within macrophages.

288 was associated with delayed clearance of H. capsulatum yeast and increased fungal burden.

289 nt in the outermost layer of the Histoplasma capsulatum yeast cell wall and contributes to pathogenes

290 ion effects of the antibodies to Hsp60 on H. capsulatum yeast cells by light microscopy, flow cytomet

291 ing MAb and were similar in appearance to H. capsulatum yeast cells.

292 ection with H. capsulatum conidia but not H. capsulatum yeast cells.

293 Growth of H. capsulatum yeast in chemically defined minimal medium wi

294 long-lasting fungistasis against Histoplasma capsulatum yeasts and that all of the fungistatic activi

295 at human dendritic cells (DC) phagocytose H. capsulatum yeasts and, unlike human macrophages (Mo) tha

296 tivity were identified by incubation with H. capsulatum yeasts for 24 h and by quantifying the subseq

297 HNP-2, and HNP-3 inhibited the growth of H. capsulatum yeasts in a concentration-dependent manner wi

298 infection of the mammalian host, Histoplasma capsulatum yeasts survive and reside within macrophages

299 an override one of the strategies used by H. capsulatum yeasts to survive intracellularly within Mo.

300 estored in the presence of wild-type (WT) H. capsulatum yeasts, or the hydroxamate siderophore, rhodo

301 ed the capacity of DC to kill and degrade H. capsulatum yeasts.

302 inst sublethal and lethal challenges with H. capsulatum yeasts.

303 ted additive fungistatic activity against H. capsulatum yeasts.

304 ibited no significant fungistasis against H. capsulatum yeasts.