ライフサイエンスコーパス: carbamyl phosphate

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1 o subunits that act in concert to synthesize carbamyl phosphate.

2 l-L-citrulline from N-acetyl-L-ornithine and carbamyl phosphate.

3 ate, whereas CPS.B uses a second ATP to form carbamyl phosphate.

4 roduction of L-citrulline and phosphate from carbamyl phosphate and L-ornithine in L-arginine biosynt

5 f this novel transcarbamylase complexed with carbamyl phosphate and N-succinyl-L-norvaline, as well a

6 e of Escherichia coli ATCase maintained with carbamyl phosphate and succinate, phosphonoacetamide and

7 ytic subunit (c3) and holoenzyme (c6r6) with carbamyl phosphate are different.

8 distance is 45.2 A) when ATCase is bound to carbamyl phosphate (CP) and to L-alanosine (an analogue

9 at 5-N of glutamine is directly channeled to carbamyl phosphate (CP) synthesis.

10 to the synthetase domain (CPS domain), where carbamyl phosphate formation is catalyzed in three conse

11 enzyme, was 2 mol of ATP utilized per mol of carbamyl phosphate formed.

12 In UV difference and 31P-NMR spectra, carbamyl phosphate-induced effects associated with wild-

13 sfers ammonia to the synthetase domain where carbamyl phosphate is formed in a three-step reaction se

14 other ligands (N-phosphonacetyl-L-aspartate, carbamyl phosphate plus malonate, phosphonoacetamide plu

15 nthesis reaction of biotin carboxylase where carbamyl phosphate reacted with ADP by holoBCCP87 was 5-

16 minimal medium and can suppress mutations in carbamyl phosphate synthase-aspartate carbamyl transfera

17 nzymes, ornithine transcarbamylase (OTC) and carbamyl-phosphate synthase (CPS), as well as dibasic am

18 omains of CAD stimulates glutamine-dependent carbamyl phosphate synthesis and abolishes the ammonia-d

19 e enzyme can also catalyze ammonia-dependent carbamyl phosphate synthesis if provided with exogenous

20 utant not only catalyzed glutamine-dependent carbamyl phosphate synthesis, but was activated 10-fold

21 of reactions involved in glutamine-dependent carbamyl phosphate synthesis.

22 he E. coli enzyme was also found to catalyze carbamyl phosphate synthesis.

23 e 150-kDa band revealed sequence identity to carbamyl phosphate synthetase I (CPS I) and a high degre

24 rotein induced the activity of mouse hepatic carbamyl phosphate synthetase I (CpsI) 5-fold.

25 alogue of molecular changes in patients with carbamyl phosphate synthetase I (CPSI) deficiency to dev

26 Human carbamyl phosphate synthetase I (CPSI) is an essential h

27 In animals, UTP feedback inhibition of carbamyl phosphate synthetase II (CPSase) controls pyrim

28 on the hydrolysis of glutamine catalyzed by carbamyl phosphate synthetase of Escherichia coli.

29 lated trifunctional enzyme known as CAD (for carbamyl phosphate synthetase, aspartate transcarbamylas

30 d-Ala d-Ala ligase, glutathione synthetase, carbamyl phosphate synthetase, N(5)-carboxyaminoimidazol

31 Escherichia coli carbamyl-phosphate synthetase consists of two subunits t

32 glutaminase domain (GLN domain) of mammalian carbamyl-phosphate synthetase II (CPSase II) catalyzes g

33 midotransferase domain (GLNase) of mammalian carbamyl-phosphate synthetase II hydrolyzes glutamine an

34 s was deleted and the sequences encoding the carbamyl-phosphate synthetase subunits were fused in fra

35 ammonia that arises by the action of PDG to carbamyl-phosphate synthetase.

36 lyzes the conversion of metabolic ammonia to carbamyl phosphate, the rate-limiting step in urea biosy

37 However, ammonia-dependent synthesis of carbamyl phosphate was abolished, indicating that ammoni

38 The K(m) values for N-acetylornithine and carbamyl phosphate were 1.05 mM and 0.01 mM, respectivel

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