ライフサイエンスコーパス: carbamylation

1 ence of four metal-mediated stages of lysine carbamylation.

2 makes it difficult to study in vivo protein carbamylation.

3 arthritis, through the mechanism of protein carbamylation.

4 loaddition, alkene dihydroxylation, and diol carbamylation.

5 at they can adapt to the presence of urea or carbamylation.

6 n asthmatic airways through a process called carbamylation.

7 Lysine carbamylation, a post-translational modification, facili

8 Carbamylation alters low-density lipoprotein (LDL) struc

9 odified online with FBDSA or in solution via carbamylation and 4-sulfophenyl isothiocyanate (SPITC) p

10 d increases the rate constants of the serial carbamylation and decarbamylation steps.

11 eversible, noncovalent complex that precedes carbamylation and increases the rate constants of the se

12 ication (i.e., 2-mercaptoethanol adducts and carbamylation) and related to their expression (i.e., an

13 alyzing mutant proteins, proteins altered by carbamylation, and cell proteins with similar amino acid

14 Q labeling, Lys methylation, acetylation and carbamylation, and Cys/Met oxidation.

15 the metal distribution to accomplish lysine carbamylation as well as subsequent enzymatic functions.

16 te (SCN(-)) as substrate to catalyze protein carbamylation, as monitored by PTM of protein lysine res

17 mechanism for cyanate formation and protein carbamylation at sites of inflammation and atherosclerot

18 been recognized that urea solution can cause carbamylation at the N termini of proteins/peptides and

19 le high-throughput pipeline: high-efficiency carbamylation blocks lysine side chains, and subsequent

20 Protein/peptide carbamylation blocks protease digestion and affects prot

21 The extent of cysteine carbamylation can be moderated by the use of scavengers.

22 Carbamylation could be minimized by desalting the cyanyl

23 homocitrulline rate, the most characteristic carbamylation-derived product (CDP), over time in skin o

24 othing is known to date about tissue protein carbamylation during aging.

25 rves as a major enzymatic source for protein carbamylation during eosinophilic inflammatory models, i

26 In addition, protein carbamylation during sample preparation makes it difficu

27 tion; however, the post-translational lysine carbamylation facilitates additional metal coordination

28 w that myeloperoxidase-catalyzed lipoprotein carbamylation facilitates multiple pro-atherosclerotic a

29 obenzamidine resulted in comparable rates of carbamylation for FXIa(WT) and FXIa(G193E), suggesting t

30 e metal is sufficient for stabilizing lysine carbamylation; however, the post-translational lysine ca

31 he most effective buffers to inhibit protein carbamylation in urea solution.

32 In this study, we compared the peptide carbamylation in urea solutions of different buffers and

33 The possible mechanism of carbamylation inhibition by ammonium-containing buffers

34 We propose that protein carbamylation is a mechanism linking inflammation, smoki

35 Carbamylation is a more recently described NEPTM that is

36 In summary, EPO-mediated protein carbamylation is promoted during allergen-induced asthma

37 nd functional impairment of proteins through carbamylation is thought to promote vascular dysfunction

38 Thus, protein carbamylation may be considered a hallmark of aging in m

39 ubisco activase facilitates this spontaneous carbamylation/metal-binding process by removing phosphor

40 Mutation of the carbamylation motif in Cx26 and mCx31 destroyed CO2 sens

41 Introducing the carbamylation motif into Cx31 created a mutant hemichann

42 A 'carbamylation motif', present in CO2-sensitive connexins

43 Our results show that carbamylation occurs throughout the whole lifespan and l

44 similarly revealed significant enrichment in carbamylation of airway proteins recovered from atopic a

45 c results that alanosine did not inhibit the carbamylation of aspartate in the normal reaction of nat

46 cell stress because of its ability to cause carbamylation of cellular proteins.

47 Carbamylation of Cx26 introduces a new transduction prin

48 C retention times (peptides with and without carbamylation of either one or both N termini).

49 Ex vivo carbamylation of LDL from healthy subjects was induced w

50 A major side reaction was identified as carbamylation of lysine residues.

51 The novel protein catalyzes the carbamylation of N-succinyl-L-ornithine but not L-ornith

52 The rate of carbamylation of NH(2)-Ile(16), which forms a salt bridg

53 Moreover, the rate of carbamylation of NH2 of Val16, which forms a salt-bridge

54 Carbamylation of proteins followed by tryptic digestion

55 duced via modification of lysine residues by carbamylation of proteins.

56 Regioselective O-carbamylation of the 1,3-dione 36 enables the transforma

57 bit the catalytic activity of CEase by rapid carbamylation of the active site, a process that shows s

58 e large subunit protein that are involved in carbamylation of the active site.

59 LY2183240 inactivates FAAH by carbamylation of the enzyme's serine nucleophile.

60 of cleavage (4 M urea, pH 7) induced partial carbamylation of the N termini of the peptides, and each

61 d products, suggesting the prominent role of carbamylation over glycoxidation reactions in age-relate

62 ummary, serum PBHCit, a footprint of protein carbamylation, predicts increased cardiovascular risk in

63 homocitrulline (PBHCit), which results from carbamylation, predicts major adverse cardiac events in

64 The first step involves a carbamylation reaction between cyanate and the nascent a

65 rom cells exposed to urea showed significant carbamylation that increased as a function of time.

66 , we describe the mechanistic details of Lys carbamylation that leads to RuBisCO activation by atmosp

67 of sulfopeptides that have been modified via carbamylation to convert all primary amines to less basi

68 be probed, and the electronic nature of the carbamylation transition state to be characterized.

69 Carbamylation was not detected if recombinant human hemo

70 plemented a derivatization strategy based on carbamylation which converts basic amine sites (Lys, N-t

71 y modifies proteins through a process called carbamylation, which promotes atherosclerosis.