ライフサイエンスコーパス: carbohydrate structure

1 AMTS13 through steric hindrance by the bulky carbohydrate structure.

2 ion sites is occupied by a high mannose-type carbohydrate structure.

3 c compounds either mimicking or masking this carbohydrate structure.

4 licit immune responses that cross-react with carbohydrate structures.

5 f galectin-3 to mucins depends on peripheral carbohydrate structures.

6 S-C, which produces mucin lacking peripheral carbohydrate structures.

7 on specific alterations in mucin-associated carbohydrate structures.

8 parameters is crucial for the elucidation of carbohydrate structures.

9 ifficulty of chemically synthesizing complex carbohydrate structures.

10 densely covered with highly branched complex carbohydrate structures.

11 Ps containing more high-mannose than complex carbohydrate structures.

12 tivity with some cross-reactivity to related carbohydrate structures.

13 same core amino acid sequence but different carbohydrate structures.

14 linkage in the expression of the two surface carbohydrate structures.

15 90, suggesting that these epitopes contained carbohydrate structures.

16 these proteins were altered by the different carbohydrate structures.

17 uch as CD34 and podocalyxin present sulfated carbohydrate structures (6-sulfated sialyl Lewis x or 6-

18 olecule and may shed light on how changes in carbohydrate structure affect protein conformation.

19 drate receptors, where the idiosyncrasies of carbohydrate structure and binding are increasingly cons

20 method has broad application for determining carbohydrate structure and conformation and to the study

21 s a new and powerful tool for characterizing carbohydrate structure and conformational dynamics in so

22 ing: Specific mutations affected the precise carbohydrate structure and folding of the HA trimer.

23 ase gene expression and enzyme activity with carbohydrate structure and function.

24 o better understand the relationship between carbohydrate structure and the stability of cholinestera

25 a role for the charge carrier as a probe of carbohydrate structure and thus have significant implica

26 se structures expand the complexity of mucin carbohydrate structure and thus the functional potential

27 cated both by the vast diversity of possible carbohydrate structures and by their dynamic nature.

28 the tremendous variation inherent in natural carbohydrate structures and their multiple biological fu

29 between expression of these two cell surface carbohydrate structures and their relative contribution

30 s show that: 1) the activity is specific for carbohydrate structure, and 2) the proliferative respons

31 tter equalizes the sensitivities for diverse carbohydrate structures, and has the potential to remove

32 ses because of the observation that specific carbohydrate structures appear in specific spatial and t

33 Carbohydrate structures are modified and degraded in the

34 in 1 significantly reduced the addition of a carbohydrate structure at this site.

35 highest activity toward GalNAcbeta1-4GlcNAc carbohydrate structures at the non-reducing termini of o

36 IgG is a glycoprotein with an N-linked carbohydrate structure attached to the CH2 domain of eac

37 idues 1-49 of the activation peptide or with carbohydrate structures attached to these residues.

38 Here, we examine a variety of protonated carbohydrate structures by gas-phase hydrogen/deuterium

39 The array of carbohydrate structures carried on lipopolysaccharides c

40 of TN-R modification with distinct sulfated carbohydrate structures changes dramatically over the co

41 rature range, the separation selectivity was carbohydrate structure dependent.

42 hope to inspire more researchers to consider carbohydrate structure, diversity, and binding as attrac

43 aliquots containing low picomole amounts of carbohydrate structures either enzymatically released fr

44 n arrays as tools for the elucidation of the carbohydrate structures expressed on cell surfaces.

45 gest novel strategies, based on the relevant carbohydrate structures, for promoting or inhibiting the

46 e majority of these antibodies recognize the carbohydrate structure Gal(alphal,3)Gal (gal epitope) pr

47 mate antibodies is a terminal galalpha1-3gal carbohydrate structure (gal antigen) present on glycolip

48 ind to terminal galactose alpha1,3-galactose carbohydrate structures (Gal) are present in humans and

49 The improved Carbohydrate Structure Generalization Scheme has been de

50 The addition of a carbohydrate structure in the N-terminal domain of PEN-2

51 was 2.1 nm, and is consistent with extended carbohydrate structures in CEA.

52 pecies-specific and individual variations in carbohydrate structures, including histo-blood group oli

53 This has been validated for several diverse carbohydrate structures, including series of malto- and

54 Several studies have proposed certain carbohydrate structures, including sLex and related stru

55 This lectin binds to high mannose carbohydrate structures, including those found on viruse

56 Expression of this unique sulfated carbohydrate structure is also temporally regulated, inc

57 carbohydrate specificity toward the O-linked carbohydrate structure known as Thomsen-Friedenreich ant

58 HuNV attaches to cell surface carbohydrate structures known as histo-blood group antig

59 ly with high mannose and fucosylated neutral carbohydrate structures, langerin has the ability to bin

60 ymes indicate that the microheterogeneity in carbohydrate structure may be responsible, in part, for

61 fect Gram-positive bacteria target cell wall carbohydrate structures, molecular mechanisms that confe

62 The heterogeneity of carbohydrate structures must represent the accessibility

63 as Lex, and clone 23 also binds the backbone carbohydrate structure nLacCer.

64 Disruption of the extensive carbohydrate structure normally present on alpha-dystrog

65 The membrane-distal repeated carbohydrate structure of LPS, the O antigen, can preven

66 trating the essential role of preserving the carbohydrate structure of mannan.

67 The carbohydrate structures of beta1-LAP are not required fo

68 To study the role of the carbohydrate structures of beta1-LAP in its biological f

69 ties, many of which are linked with specific carbohydrate structures of MFGM glycoconjugates.

70 Accumulating evidence is elucidating surface carbohydrate structures of symbiotic bacteria that drive

71 The carbohydrate structures of the Fv glycans and their impa

72 rence of type 1-piliated Escherichia coli to carbohydrate structures of vaginal mucosa plays a major

73 To investigate the effect of carbohydrate structure on Ab function, we have now expre

74 -react with highly similar or even identical carbohydrate structures on a variety of different natura

75 lar ligands, the function(s) of more generic carbohydrate structures on alpha-dystroglycan remain unc

76 The astounding number and complexity of carbohydrate structures on cell surfaces added support t

77 t from small molecules capable of perturbing carbohydrate structures on cells.

78 However, the subsets of carbohydrate structures on GPIbalpha recognized by the b

79 high-affinity binding to distinct sialylated carbohydrate structures on human platelets and salivary

80 ntibodies and their relationships to similar carbohydrate structures on infectious organisms, particu

81 the innate immune system showing binding to carbohydrate structures on microorganisms in a calcium-d

82 Sialylated carbohydrate structures on mucin play a role in adhesive

83 pattern recognition receptors that recognize carbohydrate structures on pathogens and self-Ags often

84 e C-type lectins that recognize cell surface carbohydrate structures on pathogens, and trigger killin

85 es use surface lectins to bind to sialylated carbohydrate structures on porcine endothelium, and indi

86 Hi microarrays for exploring the presence of carbohydrate structures on the bacterial surface.

87 fied by a diverse and abundant repertoire of carbohydrate structures on the cell surface, which is kn

88 ion dimerized, providing clear evidence that carbohydrate structures on the extracellular domain do n

89 human gastric epithelium, and its mimicry by carbohydrate structures on the surface of H. pylori may

90 hyaluronic acid on DCs and removal of these carbohydrate structures partially abrogated LC-DC cluste

91 apid and unambiguous distinction of isomeric carbohydrate structures persists as a tremendous analyti

92 Carbohydrate structures play important roles in many bio

93 y a mycobacterial phospholipid antigen whose carbohydrate structure precisely corresponds to mammalia

94 Assembly of discrete carbohydrate structures requires the coordinated activit

95 ts that they may express a novel, sialylated carbohydrate structure(s) that binds to E-selectin.

96 fication of the cyclopentyl chelate complex [carbohydrate structure-see text] as the catalyst resting

97 f the palladium cyclopentyl chelate complex [carbohydrate structure-see text] in 26% yield as a appro

98 ensitive, providing additional evidence that carbohydrate structures shield important neutralization

99 ascular mucin-type glycoproteins bearing the carbohydrate structure sialyl-Lewisx.

100 cells, that recognizes the terminal sulfated carbohydrate structure SO4-4-GalNAcbeta1,4GlcNAcbeta1,2M

101 n response to desialylated cancer-associated carbohydrate structures such as Thomsen-Friedenreich (TF

102 ess the MECA-79 epitope, an unusual sulfated carbohydrate structure that belongs to an important clas

103 One carbohydrate structure that is likely to be important in

104 jejuni possesses an extensive repertoire of carbohydrate structures that decorate both protein and n

105 umber of bacteria have been found to express carbohydrate structures that mimic host glycans.

106 l capsular polysaccharides (CPS) are complex carbohydrate structures that play a role in the overall

107 This carbohydrate structure (the alpha-galactosyl epitope) is

108 Despite the diversity of carbohydrate structures, the core beta-D-(GlcNAc)(2) rem

109 engendered with the ability to bind specific carbohydrate structures, thereby mediating cell-cell and

110 his study is the first to characterize which carbohydrate structures they can recognize.

111 We postulate that the unusual carbohydrate structures this molecule carries could inte

112 cterial samples, allowing dynamic changes in carbohydrate structures to be studied.

113 ay consisting of approximately 180 different carbohydrate structures to identify the specific sialosi

114 rd the goal of characterizing all aspects of carbohydrate structure using a single instrument.

115 purified to apparent homogeneity, and their carbohydrate structure was examined by high-pH anion-exc

116 The three carbohydrate structures were of the biantennary complex

117 VSG and LVSR (LVS strains altered in surface carbohydrate structures) were susceptible.