ライフサイエンスコーパス: carbon-11

1 specific for MAO A (clorgyline labeled with carbon 11).

2 lective radiotracer carfentanil labeled with carbon 11.

3 n N-methyl group as a site for labeling with carbon-11.

4 rbamates and radiolabeled eight of them with carbon-11.

5 Myelin content was detected with carbon 11 ((11)C) Pittsburgh compound B (PIB).

6 The positron-emitting radionuclide carbon-11 ((11)C, t1/2 = 20.3 min) possesses the unique

7 roxybenzothiazole (2b) was radiolabeled with carbon-11 ((11)C-(2b)) and used in vivo for microPET sca

8 After radiolabeling with positron-emitting carbon-11, [(11)C]CIC-PET was conducted in longitudinal

9 ission tomographic (PET) imaging study using carbon 11 ([11C])-labeled PBR28 in patients with tempora

10 Microbial communities utilized ancient carbon (11,300 to >50,000 (14)C years) in permafrost tha

11 [1-Carbon-11]acetate has been used as a tracer for oxidativ

12 eled with the positron-emitting radioisotope carbon-11 and evaluated in ex vivo biodistribution studi

13 and potent antagonist activity suggests that carbon-11 and iodine-123 analogues may be useful as PET

14 nd pyrazinamide (PZA) have been labeled with carbon-11 and the biodistribution of each labeled drug h

15 14a, 14b, 16, and 20 were radiolabeled with carbon-11 and their log P(7.4) was calculated as a measu

16 atus between carbons 7 and 8 (7' and 8') and carbons 11 and 12 (11' and 12') as well as the methyl gr

17 s, which were conveniently radiolabeled with carbon-11, as potential positron emission tomography (PE

18 eS-IMPY ( 3, K i = 7.93 nM) was labeled with carbon-11 at its S- or N-methyl position to give [ (11)C

19 Carbon-11-carfentanil brain kinetics were monitored for

20 Carbon-11-CFT (WIN 35,428, 2 beta-carbomethoxy-3 beta-(4

21 1-[Carbon-11]-D-glucose ([11C]-glucose) is an important ima

22 ssion tomography and raclopride labeled with carbon 11 (D2/D3 receptor radioligand sensitive to compe

23 Carbon-11-EPI traces sympathetic nerve terminals in the

24 Carbon-11-EPI was added to the perfusate during wash-in

25 nthesized and successfully radiolabeled with carbon-11, fluorine-18, and gallium-68.

26 Positron emission tomography using carbon-11 hydroxyephedrine was used to characterize left

27 Carbon-11-hydroxyephedrine cardiac retention was quantif

28 Carbon-11-hydroxyephedrine is a positron-emitting tracer

29 Carbon-11 is most often incorporated into small molecule

30 Carbon-11-L-159,884 was prepared by alkylation of the no

31 the pharmacokinetics and distribution of the carbon-11 labeled 5HT2C agonists.

32 atives as functional analogues to the native carbon-11 labeled versions with similar pharmacological

33 t of 50 patients also underwent imaging with carbon 11-labeled 3-amino-4-(2-dimethylaminomethyl-pheny

34 Binary classification of carbon 11-labeled [11C]PMP acetylcholinesterase and caud

35 ion tomography (PET) tumor imaging; however, carbon 11-labeled acetate appears to show improved sensi

36 the mu-opioid receptor selective radiotracer carbon 11-labeled carfentanil during a neutral state.

37 hy with the dopamine D2 receptor radiotracer carbon 11-labeled FLB457 before and after amphetamine ad

38 Positron emission tomographic imaging with carbon 11-labeled FLB457 before and following 0.5 mg/kg

39 sitron emission tomographic D2/3 radiotracer carbon 11-labeled FLB457 in combination with the ampheta

40 are psychiatric hospital, 58 women underwent carbon 11-labeled harmine positron emission tomography.

41 underwent positron emission tomography using carbon 11-labeled N-(2-(1-(4-(2-methoxyphenyl)-1-piperaz

42 T) imaging for tau and Pittsburgh compound B carbon 11-labeled PET (PiB-PET) imaging for Abeta.

43 nderwent flortaucipir 18 T807 (18F-T807) and carbon 11-labeled Pittsburgh Compound B (11C-PiB) positr

44 F]AV-1451 PET imaging to measure tau burden, carbon 11-labeled Pittsburgh Compound B ([11C]PiB) PET i

45 inimal brain amyloid burden as measured with carbon 11-labeled Pittsburgh Compound B ([11C]PiB) posit

46 ion-based controls, underwent amyloid ligand carbon 11-labeled Pittsburgh Compound B (PiB) positron e

47 ositron emission tomography (PET) scans with carbon 11-labeled Pittsburgh Compound B (PiB), and cereb

48 Carbon 11-labeled Pittsburgh Compound B (PiB)-, florbeta

49 groups based on their amyloid load shown on carbon 11-labeled Pittsburgh Compound B positron emissio

50 ND MEASURES beta-Amyloid burden, measured by carbon 11-labeled Pittsburgh compound B positron emissio

51 lume, and Abeta deposition (quantified using carbon 11-labeled Pittsburgh compound B positron emissio

52 Disease Neuroimaging Initiative (ADNI) using carbon 11-labeled Pittsburgh Compound B scanning.

53 Positron emission tomography (PET) and carbon-11-labeled 2B-carbomethoxy-3B-(4-fluorophenyl)tro

54 ron emission tomography demonstrated reduced carbon-11-labeled 2beta-carbomethoxy-3beta-(4-fluorophen

55 Three different carbon-11-labeled catecholamines were used for positron

56 Carbon-11-labeled D2/3R agonists have been developed, bu

57 y aimed to determine the pharmacokinetics of carbon-11-labeled DACA ([11C]DACA) and evaluate the effe

58 measured at hours 1, 3, 5, and 7 by using a carbon-11-labeled imaging agent (Altropane) and positron

59 Using two analytes, carbon-11-labeled m-hydroxyephedrine and alpha-methylepi

60 Amyloid deposition was assessed using carbon-11-labeled Pittsburgh compound B positron emissio

61 Carbon-11-labeled triamcinolone acetonide was formulated

62 positron-emission tomography (PET) with the carbon-11-labeled, R-enantiomer form of PK11195 ([(11)C]

63 Carbon-11 labeling of (+)-31 yielded [(11)C]-(S)-30, whi

64 with positron emission tomography (PET) and carbon-11-labelled (R)-PK11195, a specific ligand for th

65 Carbon-11-labelled lorlatinib is routinely prepared with

66 ission tomography (PET) with the radioligand carbon-11-labelled McN-5652, which selectively labels th

67 positron emission tomography tracers such as carbon-11-labelled Pittsburgh compound-B.

68 id imaging agent, but the short half-life of carbon-11 limits its clinical viability.

69 Carbon-11-MTICU was administered to a female baboon and

70 te pyridopyrazinone derivatives labeled with carbon-11 or fluorine-18 as PDE5-specific PET tracers.

71 amenability of thioethers to be labeled with carbon-11 or fluorine-18 through S-alkylation reactions.

72 specificity for SULT1E1 can be labeled with carbon-11 or fluorine-18, in vivo assays of SULT1E1 func

73 for labeling with a positron-emitter, either carbon-11 or fluorine-18.

74 se (MTD) to evaluate normal tissue and tumor carbon-11 radiolabeled XR5000 ([11C]XR5000) pharmacokine

75 synthesized as candidates for labeling with carbon-11 ( t 1/2 = 20.4 min) and imaging of A beta plaq

76 id component with a positron emitter, either carbon-11 (t(1/2) = 20.4 min) or fluorine-18 (t(1/2) = 1

77 beled with the short-lived positron emitter, carbon-11 (t(1/2) = 20.4 min).

78 inity enantiomer ((+)-12a) were labeled with carbon-11 (t1/2 ) 20.4 min) using [11C]cyanide ion as la

79 atives with the short-lived positron emitter carbon-11 (t1/2 = 20.4 min) in generally good to high yi

80 Carbon-11-thymidine is a PET tracer of DNA synthesis and

81 Carbon-11-thymidine labeled in the ring-2 position was u

82 pine receptor ligand flumazenil labeled with carbon 11 to assess the regional brain pattern of recept

83 cyclization can be used to label drugs with carbon-11 to study their pharmacokinetics and for evalua

84 st promising ligand 6a was radiolabeled with carbon-11 to yield 16 ([(11)C]RSR-056).

85 Compared with the 20 min half-life of carbon-11 used in the most widely used tracer, Pittsburg

86 and vabicaserin (3), were radiolabeled with carbon-11 via Pictet-Spengler cyclization with [(11)C]fo

87 ed with the short-half-life positron emitter carbon-11, which is rather impractical for many PET cent