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1 ted in elevated levels of CYP2E1 and protein carbonyls).
2 4 formation is the hydrogenation of adsorbed carbonyl.
3 lysine NH3(+) group interacts with backbone carbonyl.
4 -bound hydroxide ion onto the ceramide amide carbonyl.
5 inst modifications produced by lipid-derived carbonyls.
6 r-UV irradiation, led to complete release of carbonyls.
7 nitial reaction of GSH with Michael-acceptor carbonyls.
8 ortant glutamate and three rings of backbone carbonyls.
9 d in food products by lipid-derived reactive carbonyls.
10 e of the steric hindrance exerted by the two carbonyls.
11 them the 10-(4-(3-methoxyphenyl)piperazine-1-carbonyl)-10H-phenoxazine-3-carbonitrile (16o), showed e
12 gen bonds between Calpha-H carbon donors and carbonyl acceptors on opposing helices (Calpha-H...O hor
15 ino diketone system allied to the Lewis acid carbonyl activator BF3 were strategically employed for t
20 nd dimerization of the resultant alpha-amino carbonyls all complicated the syntheses of the dihydro-4
22 carbonyls can be produced more rapidly than carbonyl-amine reactions, therefore providing a satisfac
24 -diazo-5-oxo-2-(((phenyl(pivaloyloxy)methoxy)carbonyl)amino)hexanoate (13d), was stable in swine and
25 ethyl-4-(((1(R)-(3-(11)C-methylphenyl)ethoxy)carbonyl)amino)isoxazol-5 -yl)-[1,1'-biphenyl]-4-yl)cycl
26 -(3-{1-carboxy-5-[(6-(18)F-fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-p entanedioic acid) and
27 -11, 2-(3-{1-carboxy-5-[(6-fluoro-pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentaned ioic acid (DCF
28 e that involvement of the peptide backbone's carbonyl and amide groups in hydrogen-bond stabilization
31 ne products generally formed in reactions of carbonyl and dicarbonyl compounds with H2 O2 were not de
32 ines have dramatically expanded the scope of carbonyl and iminyl chemistry by facilitating reactions
34 ecific electrostatic interaction between the carbonyl and the azide beta-nitrogen, which stabilizes t
36 tryptophan loss and the formation of protein carbonyls and iron had a clear dose-effect in most syste
37 zyme activity but reduced protein oxidation (carbonyls) and the concentration of IL-1beta, IL-6, TNF-
39 functional group fractions (including acids, carbonyls, aromatics, and aliphatics) were calculated to
40 ecular radical aziridination of this type of carbonyl azides, allowing for high-yielding formation of
42 ing ylide then rearranges, using an internal carbonyl base, to form an enol that leads to the product
43 ior performance of isatins compared to other carbonyl based dienophiles was demonstrated and rational
44 oxy-1-phenyl-3,4-tetrahydroisoquinoline-1H-2-carbonyl)benzenes ulfonamide (30) exhibited a remarkable
45 hCA II with 4-(3,4-dihydro-1H-isoquinoline-2-carbonyl)benzenesulfonamide (3) (PDB code 4Z1J ), a nove
47 A new one-pot approach to construct alpha-carbonyl bicyclic furans from easily accessible diynones
48 i-p-topyldiaryldi(2-pyrrolyl)methane)bis(2,2'carbonyl)bis(azanediyl )) diethaneamine.2HCl] (8) select
50 bond (the alpha rotation) and about the aryl-carbonyl bond (the beta rotation) are independent, and t
51 erates the active trans-isomer competent for carbonyl bond activation by active-site residues, thereb
53 ggested to modify the lipid-derived reactive carbonyl but not the reaction mechanism because the Ea o
54 ations involving radicals derived from amide carbonyls by single electron transfer take place under m
55 ed by single electron transfer to amide-type carbonyls by SmI2-H2O-LiBr, provide efficient access to
56 de evidence consistent with the reduction of carbonyls by SmI2-water proceeding through proton-couple
58 l reactions involving lipid-derived reactive carbonyls can be produced more rapidly than carbonyl-ami
60 s well as for the selective cyanation of the carbonyl carbon atom linked to the N atom of proline res
61 Cys, Ser, or Thr side chain and the backbone carbonyl carbon to form a thiazoline, oxazoline, or meth
63 eristic of Snn are the two downfield shifted carbonyl chemical shifts, the chemical shift correlation
64 alkene instead of npi* excited state of the carbonyl chromophore in a "transposed Paterno-Buchi" rea
65 ysis of six standards representing different carbonyl classes, acetaldehyde could be ionized only aft
68 proximately hydroxyl (OH) > nitrate (ONO2) > carbonyl (CO) approximately ester (COO) > methylene (CH2
69 CORP-1) incorporates 1 such that neither the carbonyl complex nor its photoproduct(s) exits the polym
71 ons between low-valent Rh(I) and Ir(I) metal-carbonyl complexes and arylnitrile oxides possess the el
72 scribe the synthesis of reduced iron-hydride/carbonyl complexes that enable an electrophile-promoted
75 related to their ability to trap rapidly the carbonyl compound, avoiding in this way the reaction of
80 e extraction and UFLC-DAD-ESI-MS analysis of carbonyl compounds (CCs) in oils heated to 180 degrees C
82 mote the Michael reaction between enolizable carbonyl compounds and nitroolefins with excellent enant
85 g reactions of aryl groups with alpha-fluoro carbonyl compounds catalyzed by palladium complexes have
86 allows direct access to chiral beta-alkynyl carbonyl compounds employing allylic alcohol substrates
87 oach to the asymmetric synthesis of valuable carbonyl compounds from easily accessed starting materia
90 nation experiments revealed that addition of carbonyl compounds increased trigeminal burn perception
91 carbenoid insertion reaction of alpha-diazo carbonyl compounds into Si-H and S-H bonds was developed
92 terials in the hydrogenation of nitriles and carbonyl compounds is strongly influenced by the modific
93 which are precursors to valuable beta-amino carbonyl compounds such as beta-amino amides and esters,
94 aliphatic nitriles to alpha,beta-unsaturated carbonyl compounds under mild, neutral conditions is rep
97 yse the reductive coupling of a broad set of carbonyl compounds with a variety of primary and seconda
98 ) F]trifluoromethylthiolation of alpha-bromo carbonyl compounds with broad substrate scope and compat
99 omplexity associated with the interaction of carbonyl compounds with hydroperoxides and H2O2 in acidi
100 ols, 11 acids, 39 esters, 8 hydrocarbons, 14 carbonyl compounds, 17 terpenes, and 6 other compounds.
101 novel strategy for the utilization of simple carbonyl compounds, aldehydes and ketones, as intermolec
102 tween electronically or sterically different carbonyl compounds, allylmagnesium reagents reacted with
103 -catalyst for the hydrosilative reduction of carbonyl compounds, and in most cases at room temperatur
104 that additions of allylmagnesium halides to carbonyl compounds, unlike additions of other organomagn
105 e tool for the alpha- and beta-activation of carbonyl compounds, via HOMO, SOMO or LUMO activation pa
114 e, toluene, ethylbenzene, and xylene (BTEX); carbonyl compounds; and polycyclic aromatic hydrocarbons
116 ation method enables one to identify various carbonyl containing functional groups by infrared spectr
117 lative contributions of two broad classes of carbonyl-containing compounds, ketones/aldehydes versus
118 stidine, cysteine, or lysine residues to the carbonyl-containing histidine oxidation intermediates to
119 tuted THQ analogues that incorporate various carbonyl-containing moieties to maintain DOR affinity an
120 as a linchpin to introduce a broad range of carbonyl-containing pharmacophores onto oligopeptides, t
121 electivity for the formation of multi-carbon carbonyl-containing products, which we hypothesize to be
123 method resulted in three to fourfold larger carbonyl content determined in chicken, pork and beef (2
125 -diethylamino-3-((((2-maleimidyl)ethyl)amino)carbonyl) coumarin) placed at the same positions, which
126 ed annulation chemistry where initial alkyne-carbonyl coupling is followed by a second, now intramole
128 function induced by mitochondrial ionophore, carbonyl cyanide m-chlorophenyl hydrazone and other resp
129 translocation to mitochondria in response to carbonyl cyanide m-chlorophenylhydrazone treatment.
133 cascade triggered by reduction of amide-type carbonyls delivers novel, complex tetracyclic architectu
134 lkynyl halo-Prins reaction joins an enyne, a carbonyl derivative, and either a chloride, bromide, or
137 ts that with the exposure to radiations, the carbonyl double bonds break affording oxo-radicals that
138 onstrate that zinc homoenolates can react as carbonyl-electrophiles in the presence of nucleophilic a
139 tion of GSH with nine alpha,beta-unsaturated carbonyls employing high performance liquid chromatograp
141 species were identified by NMR from distinct carbonyl environments resonating at deltaC approximately
143 tadienyl and carboranyl ligands on the metal carbonyl, explain the ease of the chemical processes and
145 : reduced tryptophan fluorescence intensity, carbonyl formation, and extensive polymerization of myos
146 superposition of similar absorption bands of carbonyl functional groups summing up to a broad, nondis
147 s developed to date for the hydrogenation of carbonyl functionalities (loadings up to approximately 1
149 lectron-rich arenes to the alpha-position of carbonyl functionality of in situ generated masked benzo
152 pective is focused on alpha,beta-unsaturated carbonyls given their preponderance in bioactive natural
154 designed by bioisosteric replacement of the carbonyl group at position 2 in a series of 3,4-dihydrop
155 Thr196 residue of SpnF and the substrate C15 carbonyl group contributes to the enhancement of the rat
160 rophile preorganization by coordination to a carbonyl group likely play a role in controlling the rea
161 ety being the most preferred followed by the carbonyl group of aryl aldehyde and the aryl methane.
164 ncreases the susceptibility of a coordinated carbonyl group to nucleophilic addition in the former, f
165 f the amide spacer and the direct linkage of carbonyl group to the gamma-pyrone ring, along with the
167 unctionality of the oxygen atom of the ester carbonyl group via noncovalent interaction, which provid
168 The reaction involves methylenation of the carbonyl group with tetrahydrothiophenium ylide followed
172 Recent strategies for installing reactive carbonyl groups and alpha-nucleophiles into biomolecules
176 -) charge-dipole attraction compel the amide carbonyl groups to orient antiperiplanar to the C-F bond
178 evaluated on protein oxidation (by measuring carbonyl groups), protein nitrosation (by measuring nitr
179 yclized GNRs induces cleavage of sacrificial carbonyl groups, resulting in atomically well-defined he
181 e radical scavenging capacity, protein-bound carbonyl groups, thiol groups and metal chelation activi
182 mistry, alcohols are important precursors to carbonyl groups, which then can be converted into a wide
186 ketones to optically enriched alpha-indolic carbonyls has been accomplished using a new amino alcoho
188 ents on a water-soluble version of the metal carbonyl headgroup shows that water hydrogen bond rearra
189 evealed a different kinetics for lipid ester carbonyl hydration, suggesting that the carboxyl is link
190 yl azodicarboxylate leads to an intermediate carbonyl imide, which can react with a variety of amines
191 ion-metal-catalyzed addition of C-H bonds to carbonyls, imines, and related polarized pi bonds has em
194 level measuring overall two to fourfold more carbonyls in muscles from different species as well as i
195 ons of ammonia or ammonium sulfate (AS) with carbonyls in secondary organic aerosol (SOA) produced fr
197 l as the use of photoactive transition metal carbonyls in the presence of alkyl, fluoroalkyl, and per
198 id cycle enzyme aconitase and higher protein carbonyls; in both, lower glycolytic enzyme enolase.
206 of proteins, lactate dehydrogenase, protein carbonyl (marker of ROS), 3-nitrotyrosine (marker of RNS
208 ary and an online search program for labeled carbonyl metabolite identification based on MS, RT, and
209 e possibility of detecting a large number of carbonyl metabolites as well as high reproducibility of
210 e use of dansylhydrazine (DnsHz) labeling of carbonyl metabolites to change their chemical and physic
211 eled standards was constructed, including 78 carbonyl metabolites with each containing MS, retention
213 le ligands, including van der Waals', ionic, carbonyl, metal, hydrophobic, and halogen bond contacts,
216 mote CN group in the PivCN renders the PivCN carbonyl more electropositive and thus susceptible to nu
219 aracterized by linear atom arrangement, with carbonyl O atom positioned on the three-fold symmetry ax
220 s found to form a key hydrogen bond with the carbonyl of Leu41 in the FXIa active site, resulting in
223 ed on a novel coumarin scaffold in which the carbonyl of the lactone function of the original coumari
227 s as reactive intermediates in the catalytic carbonyl-olefin ring-closing metathesis has been obtaine
229 reductive coupling of alkenylpyridines with carbonyl or iminyl derivatives with the aid of a Lewis a
230 C)3 is more robust than Cr(0) complexes with carbonyl or monodentate isocyanides, manifesting in comp
231 irst-generation products of these reactions, carbonyl oxides (often named Criegee intermediates), is
232 Criegee intermediates are very reactive carbonyl oxides that are formed in reactions of unsatura
235 mple nonredox substitution of the C2-uridine carbonyl oxygen by sulfur is catalyzed by tRNA thiouridi
236 entify an alpha-helical switch that shifts a carbonyl oxygen into the active site to coordinate a met
238 triple bond, and solid K3PO4 interacts with carbonyl oxygen, promoting intermolecular nucleophilic a
239 rol experiments established retention of the carbonyl oxygens in the enzymatic products during the tr
241 lkenal-phenol reaction was characterized and carbonyl-phenol adducts were produced firstly by epoxide
245 tor antagonist [N2-2-2-oxoazepan-3-yl amino] carbonyl phenyl benzo (b)thiophene-2-carboxamide (ANA-12
246 which we attribute to the larger size of the carbonyl portals of CB[8]; this suggests routes to devel
247 e hydroxyl group of Hzp and a backbone amide carbonyl positioned across the dimer interface may be re
248 of several substituted N-(pivaloyloxy)alkoxy-carbonyl prodrugs of 14 designed to circulate inert in p
253 ecently developed and commercially available carbonyl-reactive tandem mass tags (aminoxyTMT) enable m
257 n as ketoreductase can be transformed from a carbonyl reductase into an initiator of radical species
258 e-pot cascades with other enzymes, including carbonyl reductases (CREDs), hydrolases and monoamine ox
259 a(2+) binding to the PI(4,5)P2 headgroup and carbonyl regions leads to confined lipid headgroup tilti
261 ish the starting pyruvate precursor from the carbonyl resonances in the resulting products, these pro
263 aliphatic aldehydes, including the reactive carbonyl species (RCS) acrolein, hydroxyl-2-nonenal, and
264 This study investigates the role of Reactive Carbonyl Species (RCS) from the Maillard reaction on bro
265 ealed that the elimination of toxic reactive carbonyl species during germination and seedling establi
266 al (MGO) and glyoxal (GO) are toxic reactive carbonyl species generated as by-products of glycolysis.
268 insertion of carbenes derived from silyl- or carbonyl-stabilized diazoalkanes into Au-C bonds at temp
269 g and aggregation was determined by inducing carbonyl stress in young mice, which recapitulated the i
270 al mol(-1) for BTP) include its high lactone carbonyl stretching energy (1821 cm(-1) in acetonitrile
271 n extended compilation of NBO charges and IR carbonyl stretching frequencies of various substituted b
272 ensional infrared (2D IR) spectroscopy, on a carbonyl stretching mode of tricarbonylchloro-9-octadecy
273 placed on the thermal evolution of the ester carbonyl stretching modes (1800-1700cm(-1)) and the comp
275 By monitoring the dynamics of the ester carbonyl stretching vibration in hydrated phosphocholine
276 ing LC-MS is a useful tool for profiling the carbonyl submetabolome of complex samples with high cove
277 abeling (CIL) LC-MS method for profiling the carbonyl submetabolome with high coverage and high accur
280 olymers derived from the copolymerization of carbonyl sulfide (COS) and epoxides by metal-free Lewis
281 ase kinetics from a series of isomeric caged-carbonyl sulfide (COS) compounds, including thiocarbamat
283 ntury that is based on long-term atmospheric carbonyl sulfide (COS) records, derived from ice-core, f
284 ical processes with variable contribution of carbonyl sulfide (OCS) shielding in an evolving volcanic
285 molation of benzyl thiocarbamates to release carbonyl sulfide, which is rapidly converted to H2S by c
286 s in non-nucleophilic substrates using alpha-carbonyl sulfoxonium ylides has not been so far investig
288 namic G:G base pairs that transit between N1-carbonyl symmetric and N1-carbonyl, N7-amino base-pairin
289 ophene-2,6-diyl][3-fluor o-2-[(2-ethylhexyl)-carbonyl]-thieno[3,4-b]thiophenediyl]]) thin films is in
290 ra methodology, was subjected to a reductive carbonyl transposition to afford 8-(4-methoxyphenyl)peri
291 use of phenolics, although the lipid-derived carbonyl trapping ability of phenolics is still poorly u
292 e (PYB) and two members of the sulfonylamino-carbonyl-triazolinone (SCT) herbicide families, revealin
293 lotris(ethane-2,1-diyl))tris(azanediyl))tris(carbonyl))tris(4-ox o-4H-pyran-3-olate) (Gd-TREN-MAM).
295 triggered by electron transfer to amide-type carbonyls, using SmI2 -H2 O, provide straightforward acc
298 eral amino acids can be oxidized to reactive carbonyls, which are often used to monitor oxidative str
299 ssed by hydrogen bonding of the cis-aldehyde carbonyl with the DHAP enamine phosphate dianion through
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