ライフサイエンスコーパス: carboxy

1 dicating HS Fe(II) in deoxy and LS Fe(II) in carboxy.

2 of nitroxide and reference hydroxylamine (3-carboxy-1-hydroxy-2,2,5,5-tetramethylpyrrolidine-1-oxyl-

3 hmdC), 5-formyl-2'-deoxycytidine (fdC) and 5-carboxy-2'-deoxycytidine (cadC) were recently discovered

4 margin; also 5-formyl-2'-deoxycytidine and 5-carboxy-2'-deoxycytidine were lower in colorectal carcin

5 -deoxycytidine, 5-formyl-2'-deoxycytidine, 5-carboxy-2'-deoxycytidine, 5-(hydroxymethyl)-2'-deoxyurid

6 (18)F-PSMA-1007 (((3S,10S,14S)-1-(4-(((S)-4-carboxy-2-((S)-4-carboxy-2-(6-(18)F-fluoronicotinamid o)

7 (((3S,10S,14S)-1-(4-(((S)-4-carboxy-2-((S)-4-carboxy-2-(6-(18)F-fluoronicotinamid o)butanamido)butana

8 in variants capable of providing access to 1-carboxy-2-aryl-cyclopropanes with high trans-(1R,2R) sel

9 action as a model system, we designed a 9-(2-carboxy-2-cyanovinyl) julolidine-based p53 peptide repor

10 hway ofPseudomonas putidaKT2440 requires a 4-carboxy-2-hydroxymuconate (CHM) hydratase (GalB), which

11 tion by identifying 5-carboxyvanillate and 4-carboxy-2-hydroxypenta-2,4-dienoate as the products and

12 l doubly caged GABA analog, termed bis-alpha-carboxy-2-nitrobenzyl-GABA (bis-CNB-GABA).

13 lcypromine 7, a known LSD1 inhibitor, with 4-carboxy-4'-carbomethoxy-2,2'-bipyridine 8 or 5-carboxy-8

14 llylamine hydrochloride and in poly-1-[p-(3'-carboxy-4'-hydroxyphenylazo) benzenesulfonamido]-1,2-eth

15 7 by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreas

16 Serum 3-carboxy-4-methyl-5-propyl-2-furanpropanoate (CMPF) (P-in

17 osapentaenoic acid (fish) (P-raw = 0.041), 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF) (

18 oxidized analogue of the natural substrate 6-carboxy-5,6,7,8-tetrahydropterin (CPH4), is shown to be

19 acterial enzyme catalyzes the formation of 6-carboxy-5,6,7,8-tetrahydropterin.

20 The PSMA-targeting Auger emitter 2-[3-[1-carboxy-5-(4-(125)I-iodo-benzoylamino)-pentyl]-ureido]-p

21 PSMA-targeted (2S)-2-(3-(1-carboxy-5-(4-(211)At-astatobenzamido)pentyl)ureido)-pent

22 PET/CT tracers, first (18)F-DCFPyL (2-(3-{1-carboxy-5-[(6-(18)F-fluoro-pyridine-3-carbonyl)-amino]-p

23 Meanwhile, MIP-1404, PSMA-11, 2-(3-{1-carboxy-5-[(6-fluoro-pyridine-3-carbonyl)-amino]-pentyl}

24 The first series contains L-Ala and D-4-carboxy-5-methyl-oxazolidin-2-one (D-Oxd).

25 -based, 4-(5-(((4-acetoxybenzyl)oxy)amino)-2-carboxy-5-oxopentyl)benzoic acid, 12, provided 5-fold hi

26 nversion of the carboxylic acid containing 7-carboxy-7-deazaguanine (CDG) into its corresponding nitr

27 7-Carboxy-7-deazaguanine (CDG) synthase (QueE) catalyzes a

28 rboxy-4'-carbomethoxy-2,2'-bipyridine 8 or 5-carboxy-8-hydroxyquinoline 9, two 2-oxoglutarate competi

29 f 5-aminoimidazole ribonucleotide (AIR) to 4-carboxy-AIR (CAIR) represents an unusual divergence in p

30 ety in adducts can produce the corresponding carboxy, aldehyde, and ketone compounds under very mild

31 In this study we show that carboxy(alkylpyrrole) protein adducts represent novel un

32 4-Carboxy-alpha-[3-(hydroxyamino)-3-oxopropyl]-benzeneprop

33 reactions for molecules containing methoxy, carboxy, amino, and sulfide substituents were carried ou

34 involve an acidic proton shared between the carboxy and amino function.

35 es C and pH 4 owing to the joint presence of carboxy and carboxylate groups.

36 OOH and -OH bonds leads to the wide range of carboxy and hydroxy functionalized alpha-amino esters (2

37 ructures of unligated (deoxy), CO-inhibited (carboxy), and O2-bound (oxy) hemes in myoglobin (MB) and

38 A general synthetic approach to vinylogous 4-carboxy- and 4-keto-2,3-dihydropyrroles is reported usin

39 We find residual carboxy- and endo-peptidase gamma-secretase activities,

40 ing the amino groups of the dendrimer with 4-carboxy-benzenesulfonamide functionalities.

41 4-, 2,6-, 2,8-quinolinediols, and 1-methyl-3-carboxy-beta-carboline are described.

42 trained so as to juxtapose the amino (N) and carboxy (C) termini; several of these designed structure

43 expression, but not the expression of a CD81 carboxy (C)-terminal deletion mutant, increases cellular

44 In Saccharomyces cerevisiae, the carboxy (C)-terminal Q/N-rich domain of the Lsm4 subunit

45 The carboxy (C)-terminal section of the polypeptide loop is

46 We find that the Brca1 carboxy (C)-terminal tandem BRCT repeat and regions of B

47 p63 also encodes multiple carboxy (C)-terminal variants.

48 signalling molecules bind to NRPs through a carboxy (C)-terminal, basic sequence motif (C-end Rule o

49 5-Formyl-dC (fdC) and 5-carboxy-dC (cadC) are newly discovered bases in the mamm

50 The liposomal 5(6)-carboxy-DCFH2 can be targeted to other tissues where oxi

51 Liposome-delivered 5(6)-carboxy-DCFH2 enabled real-time visualization and measur

52 to deliver the carboxylated derivative, 5(6)-carboxy-DCFH2, to hepatocytes in vivo.

53 the main urinary metabolite of THC, 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol (THC-COOH) with ch

54 nabidiol (CBD), and the metabolites 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol (THC-COOH), 11-hyd

55 trahydrocannabinol (11-OH-THC), and 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol glucuronide (THC-C

56 Delta9-tetrahidrocannabinol (THC), 11-nor-9-carboxy-Delta(9)-THC (THC-COOH) and 11-hidroxy-Delta(9)-

57 h abstinence before study; positive 11-nor-9-carboxy-delta-9-tetrahydrocannabinol urine levels) and c

58 rofiles of benzoylecgonine (BE) and 11-nor-9-carboxy-Delta9-tetrahydrocannabinol (THC-COOH) were show

59 ess to Nazarov cyclization precursors, alpha-carboxy divinyl ketones C.

60 on antigenic regions, we first expressed the carboxy domain of the hMPV N protein that was the most h

61 ly 20 degrees rotation between the amino and carboxy domains, which opens up a cleft in arrestin to a

62 rder to selectively capture HbA1c in sample, carboxy-EG6-undecanethiol was self-assembled on a gold t

63 ins in regulating legumain proteases via its carboxy-extended domain and papain-like proteases by its

64 led legumain (C13) protease inhibition via a carboxy-extended phytocystatin.

65 study reinforce the bifunctional ability of carboxy-extended phytocystatins in regulating legumain p

66 do derivative of the 5-carboxyl group from 5-carboxy-fluorescein diacetate or from Oregon green diace

67 spectively, cultured cells were stained with carboxy-fluorescein diacetate succinimidyl ester (CFDA S

68 lonRIalpha were measured as proliferation by carboxy-fluorescein diacetate succinimidyl ester dye dil

69 ed 2 independent assays (CD154 detection and carboxy-fluorescein succinimidyl ester dilution assays)

70 The reaction proceeded selectively at the carboxy function site to exclusively give the correspond

71 crylamide) (pCBAA), and a standard OEG-based carboxy-functional alkanethiolate self-assembled monolay

72 involved in functionalization of low-fouling carboxy-functional coatings have on the BRE capacity and

73 ith superior fouling resistance over various carboxy-functional low-fouling coatings including homopo

74 en compared with the widely used low-fouling carboxy-functional oligo(ethylene glycol) (OEG)-based al

75 oly(2-hydroxyethyl methacrylate) (pHEMA) and carboxy-functional poly(carboxybetaine acrylamide) (pCBA

76 (2-hydroxypropyl) methacrylamide (HPMAA) and carboxy-functional zwitterionic carboxybetaine methacryl

77 Carboxy-functionalised SWCNTs were covalently tethered o

78 d-supported synthetic approach using a novel carboxy-functionalized building block which bears a func

79 Lake water was dosed with AgNPs (carboxy-functionalized capping agent; approximately 10-n

80 annose and biotin ligands coupled to aqueous carboxy-functionalized gold nanoparticles through a spin

81 a and that binding did not require the gamma-carboxy glutamic acid domain.

82 The hydrogen of the free carboxy group derived from the catalyst interacts with t

83 ocenter at C2 (allylic methine, alpha to the carboxy group) and the protecting groups at C17-OH and C

84 It is revealed that, in contrast to free carboxy-group-terminated OEG-SAMs, only a partial deacti

85 IV-1 proteinase, function with two aspartate carboxy groups at the active site.

86 activation of EDC/NHS-activated zwitterionic carboxy groups by spontaneous hydrolysis is possible in

87 e) even after covalent attachment of BREs to carboxy groups of CBMAA.

88 id deactivation agents to residual activated carboxy groups of pCB.

89 specific mechanisms of EDC/NHS activation of carboxy groups, BRE attachment, and deactivation of resi

90 arrangement of oppositely charged amino and carboxy groups.

91 ise unactivated amide positioned between two carboxy groups.

92 ed from CORM-3 by following the formation of carboxy-Hmp in respiring cells.

93 ar compounds is demonstrated by formation of carboxy-Hmp.

94 ant tissues: hydroxy-IBP, 1,2-dihydroxy-IBP, carboxy-IBP and glucopyranosyloxy-hydroxy-IBP.

95 nvolving amino acid unsymmetrical urea A and carboxy-imidazolyl-dipeptide ester B intermediates.

96 direct decarboxylative arylation of 1- and 3-carboxy isoquinaldic acid N-oxides with aryl iodides is

97 out with a conjugated push-pull system and a carboxy linker for a conceivable coupling with biomolecu

98 evented by disrupting the interaction of the carboxy-lobe of calmodulin with a calmodulin-binding dom

99 e also proposed for future investigation: 4'-carboxy-mephedrone, 4'-carboxy-normephedrone, 1-dihydro-

100 Xanthan, locust bean, guar and carboxy methyl cellulose significantly enhanced Bostwick

101 Different ingredients (guar, xanthan, carboxy methyl cellulose, locust bean gums, potato fiber

102 cytochrome c by replacing tyrosine 48 with p-carboxy-methyl-l-phenylalanine (pCMF).

103 trations of the NOC-specific DNA adduct O(6)-carboxy-methylguanine when pork underwent a more intense

104 ure investigation: 4'-carboxy-mephedrone, 4'-carboxy-normephedrone, 1-dihydro-mephedrone, 1-dihydro-n

105 a nucleoside monophosphonate scaffold, alpha-carboxy nucleoside phosphonate (alpha-CNP), was designed

106 reverse transcriptase (RT) inhibitors, alpha-carboxy nucleoside phosphonates (alpha-CNPs).

107 unrecognized aminopeptidase activity but no carboxy- or endopeptidase activity.

108 combining alpha-amylase, protease and gamma-carboxy peptidase allowing complete sample preparation w

109 For example, for mono(2-ethyl-carboxy-propyl) phthalate (MECPP), a metabolite of di(2-

110 functions as a soluble glycoprotein via its carboxy-proximal Fas1 domain and its normal cellular tra

111 ntly by molecular interactions involving its carboxy-proximal fasciclin 1 domain and that its amino-p

112 The drug (R)-1-[6-[(R)-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl]pyrrolidine-2-ca

113 DFT calculations show that (amino)(carboxy) radicals evolve from C-centered radical to ambi

114 A series of monomeric (amino)(carboxy) radicals featuring carbonyl substituents with i

115 Although (amino)(carboxy) radicals had been previously considered as high

116 enzyme that recognizes the unique metabolite carboxy-S-adenosine-L-methionine (Cx-SAM) and catalyzes

117 in of MccB and the MccS enzyme that produces carboxy-SAM, which serves as a donor of the carboxymethy

118 ) or pH (pH(i)) were measured with Indo-1 or Carboxy-SNARF, respectively.

119 firmed by using the ratiometric pH indicator carboxy-SNARF-1.

120 targeted to the Z ring through the conserved carboxy tail of FtsZ leading to breakage of FtsZ filamen

121 a2+ regulation, and transplanting the NaV1.4 carboxy tail onto Ca2+ channels recapitulates Ca2+ regul

122 distinct ion channel superfamilies, yet the carboxy tails of these channels exhibit high homology, h

123 ing from neutral and deprotonated forms of 4-carboxy-TEMPO have been measured in solution (acetonitri

124 s to protein storage vacuoles is mediated by carboxy terminal and internal sorting determinants (ISDs

125 residues for DNA binding in cGAS as well as carboxy terminal tail domain for transducing signals in

126 SPAK possesses a conserved carboxy-terminal (CCT) domain, which recognises RFXV/I m

127 Here we identify the carboxy-terminal acidic tail of the yeast lipin Pah1p as

128 tment and the tagging of nascent chains with carboxy-terminal Ala and Thr extensions ("CAT tails").

129 -dependent ubiquitination and Rqc2p-mediated Carboxy-terminal Alanine and Threonine (CAT) tail elonga

130 from classical IgE by the replacement of two carboxy-terminal amino acids with eight novel residues t

131 s a metalloproteinase catalytic domain and a carboxy-terminal ancillary domain, the latter determinin

132 hotspots, requiring the repair functions of carboxy-terminal binding protein (CtBP)-interacting prot

133 The carboxy-terminal binding protein (CtBP)-interacting prot

134 S effector TRP120 is conjugated to SUMO at a carboxy-terminal canonical consensus SUMO conjugation mo

135 an amino-terminal alpha-helical region and a carboxy-terminal caspase-like catalytic domain.

136 pha), and bone metabolism (osteocalcin [OC], carboxy-terminal collagen crosslinks [CTX], and N-termin

137 ) RNA requires additional phosphorylation of carboxy-terminal Dicer residues (S1728 and S1852).

138 n and processing, and the role of the Pol II carboxy-terminal domain (CTD) in regulating these proces

139 man immunodeficiency virus type 1 (HIV-1) CA carboxy-terminal domain (CTD) is essential for CA-CA int

140 In mammals, the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II

141 i-subunit complex stably associated with the carboxy-terminal domain (CTD) of RNA polymerase II (RNAP

142 2)-Pro(3)-Thr(4)-Ser(5)-Pro(6)-Ser(7) in the carboxy-terminal domain (CTD) of the largest RNA polymer

143 The carboxy-terminal domain (CTD) of the RNA polymerase II (

144 inase 9 (CDK9) recruitment and phospho-Ser 2 carboxy-terminal domain (CTD) RNA polymerase (Pol) II fo

145 its, a core that binds UPF1 and a protruding carboxy-terminal domain (CTD) that binds the SMG1 kinase

146 n of the amino-terminal domain (NTD) and the carboxy-terminal domain (CTD) was found to be essential

147 s Pol II around the Rpb4-Rpb7 stalk near the carboxy-terminal domain (CTD).

148 is its long C-terminal extension, called the carboxy-terminal domain (CTD).

149 We recently showed that the carboxy-terminal domain (Cterm) of human mt-leucyl tRNA

150 using a recombinant OcXII harboring only the carboxy-terminal domain and this part did not exhibit an

151 The Elp1 carboxy-terminal domain contains a highly conserved argi

152 and involving a region of the middle domain/carboxy-terminal domain interface previously suggested t

153 utionarily restrictive catalytic core domain-carboxy-terminal domain linker regions.

154 The carboxy-terminal domain of DNTTIP1 has a structure relat

155 between FMRP and Ca(V)2.2 occurs between the carboxy-terminal domain of FMRP and domains of Ca(V)2.2

156 We determined the crystal structure of the carboxy-terminal domain of human SRAP and found that it

157 Our results show that the carboxy-terminal domain of N protein, N3, is necessary a

158 is model suggested that POA binds within the carboxy-terminal domain of ribosomal protein S1 (RpsA) a

159 gulates transcription by phosphorylating the carboxy-terminal domain of RNA polymerase II.

160 t the Na(+)-K(+)-ATPase, upon binding to the carboxy-terminal domain of the alpha subunit of the chan

161 The RVA PDE forms the carboxy-terminal domain of the minor core protein VP3 (V

162 The carboxy-terminal domain of the receptor shows an extensi

163 binding motifs and instead is similar to the carboxy-terminal domain of the yeast spliceosome protein

164 tion results in premature termination of the carboxy-terminal domain of VIR, resembling McClintock's

165 The carboxy-terminal domain of YTHDF2 selectively binds to m

166 novel interaction between tRNA and the Elp1 carboxy-terminal domain.

167 s secreted by T9SSs typically have conserved carboxy-terminal domains (CTDs) belonging to the TIGRFAM

168 cretion of numerous other proteins that have carboxy-terminal domains associated with targeting to th

169 catalytic core domain flanked by amino- and carboxy-terminal domains essential for the concerted int

170 Carboxy-terminal domains line the central ion pore, and

171 arged regions conserved in the J-domains and carboxy-terminal domains of each J-protein class, and ar

172 d amino-terminal and the leucine-rich repeat carboxy-terminal domains of Tmod.

173 These include rotation of the amino- and carboxy-terminal domains relative to each other, and a m

174 of phosphorylation in the amino-terminal and carboxy-terminal domains that are positioned to alloster

175 l as alpharetroviruses by providing critical carboxy-terminal domains to the intasome core that canno

176 and STING interacted directly, through their carboxy-terminal domains, to promote STING dimerization,

177 ngage the core structure via their integrase carboxy-terminal domains.

178 on coded a truncated protein that lacked the carboxy-terminal end of the VWF protein.

179 amino-terminal end and hexahistidine at the carboxy-terminal end to generate CPD-MAGE-A3 in a pQE-70

180 -381 and serine-382, located in the C-linker carboxy-terminal end, which prevent KAT2 surface express

181 Similar acidic sequences are present in the carboxy-terminal ends of all yeast lipin orthologues.

182 robably impacts Cre activity in strains with carboxy-terminal Ert2 fusion.

183 rice, OcXII is the only gene possessing this carboxy-terminal extension.

184 aused by elevated levels of the beta-cleaved carboxy-terminal fragment of APP (betaCTF).

185 We identify higher molecular mass carboxy-terminal fragments (CTFs) of APP, termed CTF-eta

186 Its catalytic domain comprises the carboxy-terminal half (containing TM6-10) and envelops t

187 the lamin-A binding domain was mapped to the carboxy-terminal half of matrin-3.

188 on depends on a beta-propeller domain in the carboxy-terminal half of the protein, which is fused to

189 Three layers of hydrophobic residues on the carboxy-terminal half of the TM1 helices form a bottlene

190 ostly rigid body movements of the amino- and carboxy-terminal halves of SecY.

191 We therefore propose that the carboxy-terminal helicase module of Brr2p acquired a reg

192 proaches, we investigated interaction of the carboxy-terminal helicase module, in particular the carb

193 -binding domains remain in contact via their carboxy-terminal helices.

194 Deleterious mutations of the ubiquitin carboxy-terminal hydrolase BAP1 found in cancers are pre

195 mposed of a four-helix bundle connected to a carboxy-terminal immunoglobulin (Ig)-like domain through

196 s N-SH2 domain and a previously unrecognized carboxy-terminal immunoreceptor tyrosine-based activatio

197 ese SARD (UT-69 and UT-155) also binding the carboxy-terminal ligand binding domain.

198 A carboxy-terminal linker connecting S6 and the cyclic-nuc

199 o acids between the leucine-rich repeats and carboxy-terminal low-complexity acidic region domains.

200 We identified a carboxy-terminal modification that is sufficient to conf

201 stinct from SGR in genomic location, encoded carboxy-terminal motif, and expression through plant and

202 l transfer protein (PITP) domain linked to a carboxy-terminal nodulin domain.

203 ng motifs, and the catalytic function of the carboxy-terminal PARP domain.

204 hat target the degradation of p53 and have a carboxy-terminal PDZ ligand that is required for stable

205 Finally, we found that the DAT carboxy-terminal PDZ-binding motif was required for DAT

206 al sequence, the protein was identified as a carboxy-terminal peptide of the acute phase protein seru

207 tsZ, referred to here as the CCTP (conserved carboxy-terminal peptide), is required for the interacti

208 Our work uncovers carboxy-terminal phosphorylation-independent noncanonica

209 In the structure of the complex of the carboxy-terminal portion of Na(v)1.5 (CTNa(v)1.5) with c

210 Next the carboxy-terminal portion of Ssp2 forms a complex with Sm

211 e range of potential substrates that undergo carboxy-terminal processing.

212 The carboxy-terminal proline-rich domain of DAZAP1 interacts

213 e tissue growth factor (CTGF), procollagen I carboxy-terminal propeptide (PICP), amino-telopeptide of

214 he characterization of two novel enzymes for carboxy-terminal protein modification provides novel ins

215 ralizing epitopes have been found within the carboxy-terminal receptor binding domains (RBDs) of TcdA

216 cleolar (NoLS) localization signals near the carboxy-terminal region of AAP2 (amino acid positions 14

217 inus, or deletion of regions in the internal carboxy-terminal region of E protein, led to virus atten

218 The intracellular carboxy-terminal region of each subunit contains several

219 an E3 ligase substrate adaptor DCAF1 and the carboxy-terminal region of human SAMHD1.

220 an extended alpha-helix from the disordered carboxy-terminal region of nucleoprotein-core links nucl

221 While the carboxy-terminal region of S-layer glycoproteins, consis

222 ns or deletions in the amino-terminal or the carboxy-terminal regions of the E protein were generated

223 chromes consist of a photosensory core and a carboxy-terminal regulatory domain.

224 (iii) However, the carboxy-terminal repeat in the VEEV HVD is indispensable

225 acid composition and charge at the six most carboxy-terminal residues.

226 fs in Slx5 to aid in substrate targeting and carboxy-terminal RING domains in both Slx5 and Slx8 for

227 -terminal helicase module, in particular the carboxy-terminal Sec63-2 domain, with the splicing RNA h

228 d with Bacillus subtilis spores expressing a carboxy-terminal segment (TcdA26-39) of C. difficile tox

229 e amino acid sequence DDDDK identical to the carboxy-terminal sequence of the FLAG epitope.

230 Cellular alpha-tubulin can bear various carboxy-terminal sequences: full-length tubulin arising

231 m substrates have been proposed to contain a carboxy-terminal signal sequence that is necessary and s

232 Several PPR proteins in plants harbor a carboxy-terminal small-MutS-related (SMR) domain, but th

233 Pre-fusion gp41 encircles amino- and carboxy-terminal strands of gp120 with four helices that

234 Here we investigate the negatively charged carboxy-terminal tail domains (CTTs) of alpha- and beta-

235 P4, has previously been shown to bind to the carboxy-terminal tail of MTA1.

236 The carboxy-terminal tail of TFAM is essential for activatio

237 dentify serine residue 1166 (Ser1166) in the carboxy-terminal tail of the NMDAR subunit GluN2B to be

238 his activation requires histidine 711 in the carboxy-terminal tail of TRPV5.

239 oth alpha- and beta-tubulin proteins possess carboxy-terminal tail regions (CTTs) that are negatively

240 with the extracellular face, rather than the carboxy-terminal tail, of the receptors.

241 The posttranslational modification of carboxy-terminal tails of tubulin plays an important rol

242 investigate the inhibition effect of tubulin carboxy-terminal tails using peptide sequences of alpha-

243 the tubulin and specifically depends on the carboxy-terminal tails.

244 Uric acid, C-reactive protein, galectin-3, carboxy-terminal telopeptide of collagen type I, and end

245 l products expressed through the cytoplasmic carboxy-terminal Toll/IL-1 domain.

246 Before insertion, the carboxy-terminal transmembrane domains of tail-anchored

247 ease domain of P3 and the domains within the carboxy-terminal two-thirds of PB2 are completely rearra

248 ith STAT3 and p300 to transactivate, whereas carboxy-terminal unphosphorylated Smad3 interacts with S

249 describe a new recombinant PRV expressing a carboxy-terminal VP26-mCherry fusion.

250 plex interacts with tubulin monomers via the carboxy-terminal winged-helix domain of Ska1, providing

251 ure with an amino-terminal coiled-coil and a carboxy-terminal zinc binuclear cluster.

252 ditionally, Rqc2 modifies stalled NCs with a carboxy-terminal, Ala- and Thr-containing extension-the

253 Furthermore, expression of carboxy-terminal-truncated VE-cadherin increases the num

254 protection was successful, and the resulting carboxy-terminated dendrimers were analyzed by NMR and D

255 olymer brushes (pCB) as well as conventional carboxy-terminated oligo(ethylene glycol)-based alkaneth

256 ly related ryanodine receptor, the cytosolic carboxy termini are uniquely arranged in a left-handed a

257 t-handed super-helical coiled-coil and their carboxy termini arrayed in a left-handed super-helical c

258 changes, with direct binding mediated by the carboxy termini of Dam1p and Duo1p.

259 While the YopD amino and carboxy termini participate in pore formation, the role

260 able region 2 (VR2) and two cysteines at the carboxy terminus (CT) as S-acylation sites.

261 For F, only the carboxy terminus (Fstem) was required, and addition of f

262 ed amphiphilic repression (EAR) motif at the carboxy terminus abolishes BZR1's abilities to regulate

263 ugh an isopeptide bond between the ubiquitin carboxy terminus and a substrate lysyl amino group.

264 Together, the data show that P, M, and the F carboxy terminus are sufficient for robust viral protein

265 The binding of receptors or their carboxy terminus as well as certain truncations induce a

266 rylation of S477 and T479 at the Akt extreme carboxy terminus by cyclin-dependent kinase 2 (Cdk2)/cyc

267 on between its HECT (homologous to the E6-AP carboxy terminus domain) and two central WW domains.

268 apsids via their amino terminus, whereas the carboxy terminus is unstructured and therefore may bette

269 dentify clusters of basic amino acids in the carboxy terminus of AAP from AAV serotype 2 (AAV2) that

270 The cytosolic carboxy terminus of AQP1 has two acidic motifs homologou

271 script stability and by restoring the native carboxy terminus of Cre, resulting in a five- to tenfold

272 A short conserved motif located at the carboxy terminus of FtsZ, referred to here as the CCTP (

273 Vpx binding domain of SAMHD1 is fused to the carboxy terminus of green fluorescent protein (GFP) and

274 dence that mapped interactions with N to the carboxy terminus of M, it was not possible to define a s

275 re mediated by a conserved region within the carboxy terminus of perilipin 1 that binds and stabilize

276 Chimeric proteins generated by fusing the carboxy terminus of perilipin 1 to the amino terminus of

277 the Tyr208Asn amino acid substitution in the carboxy terminus of SHP-1 (referred to as Ptpn6(spin) mi

278 of the NS2B/3 protease cleavage site at the carboxy terminus of the C protein.

279 tion is enhanced by a positive charge at the carboxy terminus of the peptide, which triggers an inwar

280 of interactions, one with the phosphorylated carboxy terminus of the receptor and the other with its

281 and E3 three-enzyme cascade, which links the carboxy terminus of ubiquitin to the epsilon-amino group

282 ins a tethered cluster-binding domain at its carboxy terminus that moves in and out of the active sit

283 Residues 582 to 596 in the DAT carboxy terminus were identified as the primary binding

284 between the 20 kDa amino terminus and 65 kDa carboxy terminus, after proteolytic processing.

285 tional crosstalk between the pore region and carboxy terminus, involved in Ca(2+)-calmodulin-mediated

286 IK (AAP2BR5), from the amino terminus to the carboxy terminus.

287 coding region at C329, Q330, or Y331 in the carboxy terminus.

288 lexed alone with an IQ domain on the channel carboxy terminus.

289 el CLH-3b is reduced by phosphorylation of a carboxy-terminus "activation domain," which disrupts its

290 terozygous frameshift mutation affecting the carboxy-terminus (439fs) of perilipin 1 in two unrelated

291 elices designated "A-R" and an intracellular carboxy-terminus containing two cystathionine-beta-synth

292 rylated (hp) Tau and to E3 ubiquitin ligase, carboxy-terminus of heat shock-70 interacting protein.

293 n binding (Fab) (scFab) format, in which the carboxy-terminus of the light chain is linked to the ami

294 ropose that alteration and elongation of the carboxy-terminus of the protein has a dominant-negative

295 eas deletion of the S. Typhimurium flagellin carboxy-terminus prevented caspase-1 maturation only.

296 Addition of Q17 at its carboxy-terminus reduces the extent of the main basin to

297 hanism for all domains except for the distal carboxy-terminus.

298 , and two major metabolites of THC, 11-nor-9-carboxy-THC and 11-hydroxy-THC, in active users and part

299 The alpha-carboxy-tropone substructure is ideal for this purpose a

300 ng cerebrovascular perfusion with ROX, SE (5-Carboxy-X-Rhodamine, Succinimidyl Ester), a fluorescent