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1 LMP-1's critical effector domains (i.e. the carboxy-terminus).
2 a functionally important RING domain at its carboxy terminus.
3 oteins and proteins tagged at their amino or carboxy terminus.
4 bstitutions for the aromatic residues in the carboxy terminus.
5 repeat (TR) region of the genome through its carboxy terminus.
6 in and four Kruppel-like zinc fingers at the carboxy terminus.
7 e of the amino terminus of EpoB and the EpoA carboxy terminus.
8 parS that contact the ParB protein near the carboxy terminus.
9 ts amino terminus and a kinase domain in its carboxy terminus.
10 d established a Golgi targeting motif at the carboxy terminus.
11 binding pocket in helices 2 and 3 of Pab1p's carboxy terminus.
12 product that deletes 50 amino acids near the carboxy terminus.
13 n the HMG-like DNA binding domain and at the carboxy terminus.
14 IK (AAP2BR5), from the amino terminus to the carboxy terminus.
15 s, and a predicted coiled-coil domain at the carboxy terminus.
16 the sole cysteine residue located within the carboxy terminus.
17 lting in the loss of 17 amino acids from the carboxy terminus.
18 wl', has been located to the large cytosolic carboxy terminus.
19 was present between residue 75 and the pilin carboxy terminus.
20 sing an apparently innocuous change near its carboxy terminus.
21 a CCT (CO, CO-Like, TOC1) domain near their carboxy terminus.
22 sphopeptide sequence in the highly conserved carboxy terminus.
23 of an alpha-chiral, aromatic residue on the carboxy terminus.
24 pendent on phosphorylation of the receptor's carboxy terminus.
25 its leucine-rich repeat (LRR) domain and its carboxy terminus.
26 the homologous core and in the heterogeneous carboxy terminus.
27 or without thioredoxin fused in-frame to its carboxy terminus.
28 coding region at C329, Q330, or Y331 in the carboxy terminus.
29 lexed alone with an IQ domain on the channel carboxy terminus.
30 el of the predicted structured region of the carboxy terminus.
31 ion of three serine residues in the receptor carboxy terminus.
32 nB substitutions in four regions of the TonB carboxy terminus.
33 ls between the ExbD transmembrane domain and carboxy terminus.
34 rypsin digestion sites of both the amino and carboxy terminus.
35 ucture is disordered in the highly conserved carboxy-terminus.
36 d atypically near the amino- rather than the carboxy-terminus.
37 ronectin type-III domains, and a hydrophobic carboxy-terminus.
38 represented by the crystal structure of the carboxy-terminus.
39 ly specific to SspH2 and was mediated by its carboxy-terminus.
40 hanism for all domains except for the distal carboxy-terminus.
41 f nucleotide, Hsp90 is dimerized only at the carboxy-terminus.
42 l nonamer core region at both the amino- and carboxy-terminus.
43 e 75-kd SirT1 fragment was found to lack the carboxy-terminus.
44 r Mad is activated by phosphorylation at its carboxy-terminus.
46 terozygous frameshift mutation affecting the carboxy-terminus (439fs) of perilipin 1 in two unrelated
47 ed amphiphilic repression (EAR) motif at the carboxy terminus abolishes BZR1's abilities to regulate
48 t its amino terminus and a SET domain at the carboxy terminus, abolishes H3 Lys-4 methylation in fiss
49 an ubiquitin-association (Uba) domain at the carboxy terminus, ACK1 binds to both poly- and mono-ubiq
50 el CLH-3b is reduced by phosphorylation of a carboxy-terminus "activation domain," which disrupts its
52 green fluorescent protein (EGFP) tags at the carboxy terminus, all transcript variants can be correct
53 ons between the functionally critical distal carboxy terminus alpha-helix (H6) and the proximal struc
56 al of 6 residues beginning with L-Glu at the carboxy terminus and alternating Neu2en and L-Glu residu
57 domain to a conserved sequence at the VP1/2 carboxy terminus and demonstrated that this domain suffi
58 , cysteines 754 and 759, is located near the carboxy terminus and is thought to reduce the cystine in
59 al changes that result in an exposure of the carboxy terminus and its insertion into the lipid phase.
60 sults in the loss of 17 amino acids from the carboxy terminus and renders the envelope protein fusion
61 ber protein on ligands incorporated into its carboxy terminus and thus limited the range of potential
62 not the Delta102-139 protein, binds the p53 carboxy-terminus and diminishes its ubiquitination and n
64 minisatellite insertion that has altered the carboxy-terminus and selectively disrupted its capacity
66 one near the amino terminus and one near the carboxy terminus, and a large intervening loop that is p
67 nnel have focused on the large intracellular carboxy terminus, and much evidence supports the hypothe
68 leucine-glutamine (IQ) domain on the channel carboxy terminus, and subsequent Ca(2+) binding to this
69 Together, the data show that P, M, and the F carboxy terminus are sufficient for robust viral protein
72 ining this sequence that carry biotin on the carboxy terminus, as well as a photoactivated cross-link
73 imarily at two sites on the enzyme, with its carboxy terminus at the active site and with its amino-t
75 s a bipartite mediator nuclear export as the carboxy terminus binds HDA and the amino terminus itself
76 Rad1 is independent of Claspin and the Rad9 carboxy terminus, both of which are required for Chk1 ph
77 rylation of S477 and T479 at the Akt extreme carboxy terminus by cyclin-dependent kinase 2 (Cdk2)/cyc
78 and the TonB transmembrane domain, the TonB carboxy-terminus can form a meta-stable high-energy conf
79 located in the amino terminus and one in the carboxy terminus, can independently alter both the level
80 ing of the kinase-interacting regions of the carboxy terminus combined with structural modeling provi
81 -turn-helix (HTH) DNA-binding domain and the carboxy terminus consists of a dimerization domain with
82 elices designated "A-R" and an intracellular carboxy-terminus containing two cystathionine-beta-synth
83 0 throughout its first 551 residues, but its carboxy terminus contains a glycine/arginine-rich domain
87 tified based on ability to interact with the carboxy terminus (CT) of PABP in yeast two-hybrid and in
88 tins, hybrid compounds composed of 3 and the carboxy terminus dipeptides of dolastatin 10, or the dol
89 elongs to the Nedd4-like homologous to E6-AP carboxy terminus domain family of E3 ubiquitin ligases,
91 on between its HECT (homologous to the E6-AP carboxy terminus domain) and two central WW domains.
92 pecific loss of the HECT (homologous to E6AP carboxy terminus) domain E3 ubiquitin ligase Ube3a/E6AP.
93 show a role for the HECT (homologous to E6AP carboxy terminus) E3 ubiquitin ligase WWP-1 as a positiv
94 ll region rich in acidic residues within the carboxy terminus eliminated both the cleavage and nuclea
96 cdc34) ubiquitin-conjugating enzyme, and its carboxy terminus expresses a ubiquitin ligase activity d
99 n of a splice variant of REST that lacks the carboxy terminus has been associated with neuronal tumou
102 sesses a distinctive amino acid motif at its carboxy terminus, including a terminal phenylalanine, wh
103 uclein molecules, and a close amino terminus-carboxy terminus interaction within single alpha-synucle
104 ith the cryptic Polo box of Plk4 whereas the carboxy terminus interacts with the centriolar protein S
105 tional crosstalk between the pore region and carboxy terminus, involved in Ca(2+)-calmodulin-mediated
107 erminus, but a second function involving the carboxy terminus is also required for countering host ce
110 fferentiating osteoblasts and that the Runx2 carboxy terminus is necessary for maximal repression of
111 lation on tyrosines 421, 466, and 482 in the carboxy terminus is required for cell movement and metas
112 est that the essential function of the VP1/2 carboxy terminus is to anchor the VP1/2 tegument protein
113 apsids via their amino terminus, whereas the carboxy terminus is unstructured and therefore may bette
114 r provide evidence that the CSF-1 receptor's carboxy-terminus is a substrate for autophosphorylation.
115 n, there is evidence that the CSF-1 receptor carboxy-terminus is involved in down regulation of the r
117 analog (TP3982) was synthesized to harbor a carboxy-terminus lysine (Lys) residue separated from VIP
119 gh the all-Ala Ser(16) His(20) TMD, the TonB carboxy terminus might fold so rapidly that disulfide-li
120 ese data together with the existing Na(V)1.5 carboxy terminus nuclear magnetic resonance structure, w
121 t fusion of domain 3 of the N protein to the carboxy terminus of a heterologous protein caused it to
122 dentify clusters of basic amino acids in the carboxy terminus of AAP from AAV serotype 2 (AAV2) that
124 Here we show that the soluble cytosolic carboxy terminus of an oligomeric ammonium transporter f
127 ontaining the amino terminus of CETP and the carboxy terminus of BPI did not retain any observable CE
129 chimaeras, we demonstrate that the conserved carboxy terminus of CENP-A is necessary and sufficient f
131 ity of a stretch of basic amino acids in the carboxy terminus of Chp and that the basic amino acids w
133 script stability and by restoring the native carboxy terminus of Cre, resulting in a five- to tenfold
136 ce has been mapped to the well-characterized carboxy terminus of E3L, which contains a conserved doub
137 e proteasome, and an interaction between the carboxy terminus of E6 and the PDZ domain of PTPN3.
138 e PDZ domain-binding motif (-X-T-X-V) at the carboxy terminus of E6 is essential for targeting PDZ pr
139 ed by engineering cysteine residues into the carboxy terminus of each STAT molecule, allowing a hypot
140 in recruiting cyclin A complexes, while the carboxy terminus of EBNA3C is necessary for the function
141 this report we demonstrate that although the carboxy terminus of EBNA3C predominantly regulates cycli
143 Cyclin A interacted with a region of the carboxy terminus of EBNA3C, shown to be important both f
144 leting a single amino acid from the amino or carboxy terminus of either peptide markedly reduced IFN-
146 Removal of three lysine residues from the carboxy terminus of ErpP significantly reduced binding o
150 a Gbetagamma inhibitor peptide derived from carboxy terminus of G protein-coupled receptor kinase 2
153 and carboxy-terminal halves of gp120 and the carboxy terminus of gp41 contributed to the neutralizati
154 Vpx binding domain of SAMHD1 is fused to the carboxy terminus of green fluorescent protein (GFP) and
155 Removal of a PDZ domain-binding motif at the carboxy terminus of hH1 did not alter the PKA response.
157 asing the stability of Smad3 in an E3 ligase carboxy terminus of Hsc70-interacting protein-dependent
160 A critical mediator of this mechanism was carboxy terminus of Hsp70-interacting protein (CHIP), a
163 e chimera containing the TD of KCNQ1 and the carboxy terminus of KCNQ4 yielded current density 10- or
164 ntrast to previous models, we found that the carboxy terminus of Ku80 is not absolutely required for
166 hat this 31-kDa antigen was derived from the carboxy terminus of LipL45; therefore, it was designated
167 ed fluorescent protein fused in frame at the carboxy terminus of M [MmRFP]) at the G-L gene junction,
168 dence that mapped interactions with N to the carboxy terminus of M, it was not possible to define a s
170 terminus of NA from the PR8 strain with the carboxy terminus of NA from VN1203, the surface epitopes
171 analysis suggests that large portions of the carboxy terminus of NS5A are in an unfolded and disorder
173 mutagenesis experiments determined that the carboxy terminus of p28 is not required for its interact
176 re mediated by a conserved region within the carboxy terminus of perilipin 1 that binds and stabilize
177 Chimeric proteins generated by fusing the carboxy terminus of perilipin 1 to the amino terminus of
180 omplex reveals the complete unfolding of the carboxy terminus of Prx, and its unexpected packing onto
182 gnaling complex exists in the absence of the carboxy terminus of Rad9 and that this carboxy-terminal
183 s is consistent with the hypothesis that the carboxy terminus of Rex-2 contains a novel domain that i
189 no terminus and a shorter alpha-helix at the carboxy terminus of Scm3(CBD) wraps around the Cse4-H4 d
191 acts with Sgt1p and, in combination with the carboxy terminus of Sgt1p, regulates the interaction bet
192 the Tyr208Asn amino acid substitution in the carboxy terminus of SHP-1 (referred to as Ptpn6(spin) mi
193 t, co-expression of GFP-tagged Orai with the carboxy terminus of Stim as a cytosolic protein to activ
196 d seven sites in the proline-rich region and carboxy terminus of tau by amino acid substitution.
197 and the highly conserved KLLEGE motif at the carboxy terminus of the 2B domain of the central rod.
199 ave inserted the IgG-binding Z domain at the carboxy terminus of the coat protein and coexpressed thi
200 uded an unusual series of amino acids at the carboxy terminus of the core protein unlike that seen in
201 hat harbored a 1.2-kb insertion spanning the carboxy terminus of the envelope glycoprotein 1 (E1), th
202 04305) was homologous to the non-DNA-binding carboxy terminus of the Escherichia coli Rob transcripti
203 ioning of the NC peptide is conserved at the carboxy terminus of the Gag protein among most long term
205 -helical coiled-coil rod region--towards the carboxy terminus of the heavy chain--has unusual structu
206 ch as PMS1, MLH3 and MBD4, we identified the carboxy terminus of the human c-MYC proto-oncogene as an
207 gous domain (NUDT9 homology domain) near the carboxy terminus of the LTRPC2/TrpC7 putative cation cha
208 A conserved amphipathic alpha-helix in the carboxy terminus of the myogenic bHLH proteins has disti
209 vector containing a six-histidine tag on the carboxy terminus of the NqrF subunit, the last subunit i
210 tion is enhanced by a positive charge at the carboxy terminus of the peptide, which triggers an inwar
214 of interactions, one with the phosphorylated carboxy terminus of the receptor and the other with its
218 and E3 three-enzyme cascade, which links the carboxy terminus of ubiquitin to the epsilon-amino group
219 s study is the first to demonstrate that the carboxy terminus of US28 controls US28 signaling in the
220 s to a conformational region centered on the carboxy terminus of V4, and the epitope(s) of CG-III ant
223 sequences on the progressive deletion of the carboxy-terminus of alpha-syn in regulating fibril forma
227 rylated (hp) Tau and to E3 ubiquitin ligase, carboxy-terminus of heat shock-70 interacting protein.
228 gnaling of the nucleotide-bound state to the carboxy-terminus of Hsp82, or regulating Hsp82-Cpr6 inte
229 ions have suggested instead that in vivo the carboxy-terminus of intact TonB is dynamic and flexible.
230 ine based signal (330YSKF333) located in the carboxy-terminus of Kir6.2 and that SUR1 has no direct r
231 hat phosphorylation of kNBC1-Ser(982) in the carboxy-terminus of kNBC1 (kNBC1-Ct), by cAMP-protein ki
232 roteins bind to an acidic LXXLL motif at the carboxy-terminus of MAML1 and repress transactivation by
233 c fragment, a 10 amino acid peptide from the carboxy-terminus of proSP-B (SPTGEWLPR), from the circul
234 ns Ser119, Ser130, Thr132, and Ser138 in the carboxy-terminus of PTHrP and are associated with the ph
237 nd on the binding of calmodulin (CaM) to the carboxy-terminus of the A(2A) receptor in the A(2A)-D(2)
239 These tandem domains are attached to the carboxy-terminus of the cytolytic domain and contain a b
240 of the CAAX box from the git11 Ggamma to the carboxy-terminus of the git5 Gbeta partially suppresses
241 n binding (Fab) (scFab) format, in which the carboxy-terminus of the light chain is linked to the ami
242 ropose that alteration and elongation of the carboxy-terminus of the protein has a dominant-negative
243 le pool is signaled by an element within the carboxy-terminus of the protein, and is a cell-specific
245 opes (neoepitope from cleavage of CII [C2C], carboxy-terminus of three-quarter peptide from cleavage
246 The phenotypic results suggested that the carboxy-terminus of TonB was a flexible and dynamic doma
252 ein domain to either the amino terminus, the carboxy terminus, or to both termini of two small knotte
255 The site of CaM action within the channel carboxy terminus overlaps with that of the KCNQ opener N
257 eas deletion of the S. Typhimurium flagellin carboxy-terminus prevented caspase-1 maturation only.
258 cated RHA peptide that can bind to the BRCA1 carboxy-terminus prevents normal BRCA1 function, such as
261 lation of cortactin tyrosine residues in the carboxy terminus requires the aminoterminal domain and R
262 Here, the importance of the cytoplasmic ExbB carboxy terminus (residues 195 to 244) was evaluated by
263 1C and some of the substitutions nearest the carboxy terminus spontaneously formed disulfide cross-li
264 When the crystal structure of a dimeric TonB carboxy-terminus subsequently became available, we obser
265 otein interaction domain of gp32 (the acidic carboxy-terminus), suggesting that a specific interactio
267 the HAND-SANT-SLIDE (HSS) domain at the ISWI carboxy terminus that binds linker DNA, needed for ISWI
268 ave been identified within the intracellular carboxy terminus that can activate NF-kappaB, C-terminus
270 A peptide corresponding to a region of the carboxy terminus that is conserved in Cx36 and its two t
271 (EGFR) upon EGF stimulation via a region at carboxy terminus that is highly homologous to Gene-33/Mi
272 ins a tethered cluster-binding domain at its carboxy terminus that moves in and out of the active sit
273 , we focus on a 57-residue domain within the carboxy-terminus that is a possible PIP(2) binding site.
274 hen combined with W213C or F202C in the TonB carboxy terminus, the TonBDelta7 deletion did not preven
275 -regulate conformational changes at the TonB carboxy terminus through the all-Ala Ser(16) His(20) TMD
277 f amino acids 136 to 290 and is fused at the carboxy terminus to enhanced green fluorescent protein (
278 ioactive peptides require amidation of their carboxy terminus to exhibit full biological activity.
280 n integral membrane protein that exposes its carboxy-terminus to the intermembrane space and exists i
282 G contains a glycine and arginine-rich (RGG) carboxy terminus typically found in vertebrate nucleolin
286 ma-tubulin was specific, and function of the carboxy terminus was necessary for this reaction; trunca
288 or both beta(1)- and beta(2)AR, the receptor carboxy-terminus was uniquely responsible for scaffold i
290 n a yeast two-hybrid screen with the InsP3R1 carboxy terminus, we isolated Htt-associated protein-1A
292 nteractions between that region and the TonB carboxy terminus were identified by examining 270 combin
293 harged residues 104, 105 and 114, 115 in the carboxy-terminus were implicated in this reduced aggrega
294 us to vertebrate Nopp140 particularly in its carboxy terminus, whereas Nopp140-RGG contains a glycine
295 ometer distances after 1) truncations of the carboxy terminus, which contains a C-terminal PDZ (PSD95
296 mia virus (Mo-MuLV) Gag protein has a unique carboxy terminus with a highly charged arginine-rich seq
297 the data suggest that the interaction of Cbl carboxy terminus with CIN85 has a minor and a redundant
298 ar magnetic resonance structures of the TonB carboxy terminus with conformational changes and mutant
299 nt roles in cocrystal structures of the TonB carboxy terminus with OM transporters BtuB and FhuA.
300 h a nuclear localization signal fused to the carboxy terminus (XAP2-NLS) was utilized to test whether
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