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1 and Pol II phosphorylated at serine 5 of the carboxy-terminal domain.
2 obic membrane domain, and a long hydrophilic carboxy-terminal domain.
3 nce in protein regulation also reside in the carboxy-terminal domain.
4 ry effects identified two residues in Sis1's carboxy-terminal domain.
5 by distinguishing amino acid changes in the carboxy-terminal domain.
6 specific signal peptide present in the Reln carboxy-terminal domain.
7 with the Arp2/3 complex through a conserved carboxy-terminal domain.
8 criptional repression mediated by the XTcf-3 carboxy-terminal domain.
9 novel interaction between tRNA and the Elp1 carboxy-terminal domain.
10 Crk, Fyn, and others; and a highly conserved carboxy-terminal domain.
11 homology RNA-binding domains and an unusual carboxy-terminal domain.
12 e transmembrane domains and an intracellular carboxy-terminal domain.
13 -sensing and pore domains, and a cytoplasmic carboxy-terminal domain.
14 is activated and phosphorylates Cdc10 at its carboxy-terminal domain.
15 and increased ubiqutination within the Rbp1 carboxy-terminal domain.
16 its catalytic domain, but rather within the carboxy-terminal domain.
17 ngage the core structure via their integrase carboxy-terminal domains.
18 n between FtsZ and ZipA occurs through their carboxy-terminal domains.
19 nteracting transactivator, with Glu/Asp-rich carboxy-terminal domain 2 (CITED2), a gene that mediates
22 n response to CCL5, indicating that the US28 carboxy-terminal domain also regulates agonist-dependent
24 e conserved heptapeptide repeats in the Rpb1 carboxy-terminal domain and is mediated principally by t
25 t and Val149 --> Met) are located within the carboxy-terminal domain and maintain or improve packing
26 using a recombinant OcXII harboring only the carboxy-terminal domain and this part did not exhibit an
27 at the domain interface, with Cys217 of the carboxy terminal domain, and we suggest that these two c
28 lus subtilis ortholog YxiN have similar 75aa carboxy-terminal domains, and both proteins are specific
29 roteins, we find that sequences in the human carboxy-terminal domain are critical for telomere mainte
30 cretion of numerous other proteins that have carboxy-terminal domains associated with targeting to th
32 ge lambda nascent mRNA transcripts while the carboxy-terminal domain binds RNA polymerase and arrests
33 ST-amino-terminal domain (N-term or NTD)/GST-carboxy-terminal domain (C-term or CTD) intramolecular a
34 sense mutation occurs outside this conserved carboxy-terminal domain, closely upstream of an SIP1 (SM
35 n to target to the Golgi apparatus through a carboxy-terminal domain containing a conserved tyrosine
36 re, the cell line lex1/lex2, which lacks the carboxy-terminal domain containing the phosphorylated re
37 otein that has a unique amino-terminus and a carboxy-terminal domain containing two ankyrin-repeat mo
38 /alpha sandwich that binds OOHL, whereas the carboxy-terminal domain contains a helix turn helix DNA-
40 a "kelch" type beta-propeller fold, and the carboxy-terminal domain contains a repeat of a fibronect
41 anticipated, the enzyme contains amino- and carboxy-terminal domains corresponding to the DNA-recogn
42 ces encoding the signal peptide (SS) and the carboxy-terminal domain (CT) of beta-lactamase, and clon
43 proteins are kinases which phosphorylate the carboxy terminal domain (CTD) of RNA polymerase II (Pol
44 Cyclin T1/CDK9 complexes phosphorylate the carboxy terminal domain (CTD) of RNA polymerase II (RNAP
45 purified CDK8 in vitro for RNA polymerase II carboxy-terminal domain (CTD) and histone H3 substrates.
46 ng seven alpha-helices and a beta-hairpin, a carboxy-terminal domain (CTD) comprising four alpha-heli
48 isomerizing peptide bonds within the pol II carboxy-terminal domain (CTD) heptapeptide repeat (YSPTS
49 ame phosphorylated at serines 2 and 5 in its carboxy-terminal domain (CTD) heptapeptide repeats (YSPT
50 n and processing, and the role of the Pol II carboxy-terminal domain (CTD) in regulating these proces
51 man immunodeficiency virus type 1 (HIV-1) CA carboxy-terminal domain (CTD) is essential for CA-CA int
52 Although Bur1 can phosphorylate the Rpb1 carboxy-terminal domain (CTD) kinase in vitro, it has no
54 dentified SEM-5 as able to interact with the carboxy-terminal domain (CTD) of EGL-15, a domain that i
60 i-subunit complex stably associated with the carboxy-terminal domain (CTD) of RNA polymerase II (RNAP
62 sential for P-TEFb to hyperphosphorylate the carboxy-terminal domain (CTD) of RNA polymerase II and m
63 air which has been found associated with the carboxy-terminal domain (CTD) of RNA polymerase II holoe
64 nd P-TEFb are both able to phosphorylate the carboxy-terminal domain (CTD) of RNA polymerase II, but
70 ly with inhibition of phosphorylation in the carboxy-terminal domain (CTD) of RNApolII, as well as wi
71 biochemical approach, we have identified the carboxy-terminal domain (CTD) of Rpb1, the largest subun
74 the failure to phosphorylate serine 2 in the carboxy-terminal domain (CTD) of the large subunit of RN
75 2)-Pro(3)-Thr(4)-Ser(5)-Pro(6)-Ser(7) in the carboxy-terminal domain (CTD) of the largest RNA polymer
76 ating Ser2 of the heptapeptide repeat of the carboxy-terminal domain (CTD) of the largest subunit of
77 mably mediated by its phosphorylation of the carboxy-terminal domain (CTD) of the largest subunit of
78 as a protein kinase that phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of
79 or b (P-TEFb) through phosphorylation of the carboxy-terminal domain (CTD) of the largest subunit of
82 ach complex are known to bind pol II via the carboxy-terminal domain (CTD) of the largest subunit, Rp
85 g reactions through interactions between the carboxy-terminal domain (CTD) of the RNAP II largest sub
86 anylyltransferase Cgt1 cocrystallized with a carboxy-terminal domain (CTD) peptide composed of four S
87 gated the role of RNA polymerase II (pol II) carboxy-terminal domain (CTD) phosphorylation in pre-mRN
88 , polymerase II (Pol II), and phospho-Ser(2) carboxy-terminal domain (CTD) Pol II to the IFN-stimulat
89 lation of a heptapeptide repeat known as the carboxy-terminal domain (CTD) present in the largest sub
90 inase 9 (CDK9) recruitment and phospho-Ser 2 carboxy-terminal domain (CTD) RNA polymerase (Pol) II fo
91 mplekin in a ternary complex with the Pol II carboxy-terminal domain (CTD) Ser 5 phosphatase Ssu72 an
92 gest subunit of Pol II contains a repetitive carboxy-terminal domain (CTD) that becomes highly phosph
93 its, a core that binds UPF1 and a protruding carboxy-terminal domain (CTD) that binds the SMG1 kinase
94 n of the amino-terminal domain (NTD) and the carboxy-terminal domain (CTD) was found to be essential
95 y consist of an approximately 100-amino acid carboxy-terminal domain (CTD) with two helix-turn-helix
96 hosphorylates the RNA polymerase II (RNApII) carboxy-terminal domain (CTD) within the transcription i
97 five SRB genes, identified as suppressors of carboxy-terminal domain (CTD)-truncation mutants; produc
102 s secreted by T9SSs typically have conserved carboxy-terminal domains (CTDs) belonging to the TIGRFAM
103 e differences between HDAC1 and HDAC2, their carboxy-terminal domains (CTDs) were deleted, which led
107 ishes NPK1 activity, and the presence of the carboxy-terminal domain diminishes the kinase activity.
108 eletions in the highly conserved hydrophobic carboxy-terminal domain disrupted both protein function
109 catalytic core domain flanked by amino- and carboxy-terminal domains essential for the concerted int
110 t of two residues in the L3 loop of the Smad carboxy-terminal domain establish the specificity of rec
111 avin dinucleotide, which binds to a distinct carboxy-terminal domain, fails to alter FAC-RED complexe
112 n that functions in flagellar assembly and a carboxy-terminal domain (FliG-C) that functions specific
115 o yield a protein that retained a 57-residue carboxy terminal domain fused to the catalytic core.
116 stabilize the protein and are located in the carboxy-terminal domain generally slow the rate of foldi
117 of the beta-promoter revealed that a smaller carboxy-terminal domain generated an open promoter confi
118 emical and functional studies, that the Srs2 carboxy-terminal domain harbours tandem receptor motifs
120 lial monocyte-activating polypeptide II-like carboxy-terminal domain has potent leukocyte and monocyt
121 americ ring formed by the amino-terminal and carboxy-terminal domains, have been deleted; an asymmetr
122 cription, whereas phosphorylation within the carboxy-terminal domain II is necessary for replication.
123 results indicate that phosphorylation of the carboxy-terminal domain II residues of P protein are req
124 o examine the role of phosphorylation of the carboxy-terminal domain II residues of the P protein in
125 trate for the first time that the 57-residue carboxy-terminal domain in CCTalpha participates in lipi
126 se-resistant domain and a protease-sensitive carboxy-terminal domain in N-218 MLN64 is similar to the
128 via one transmembrane domain with amino- and carboxy-terminal domains in the cytoplasm and periplasm,
130 B protein (CSB) or overexpression of the p53 carboxy-terminal domain induces fragility of the same lo
131 of assembly not driven by the strong capsid carboxy-terminal domain interactions that characterise c
132 and involving a region of the middle domain/carboxy-terminal domain interface previously suggested t
133 f serine residues 151 and 153 within a novel carboxy-terminal domain is critical for function in vivo
134 lyses of stable cell lines revealed that the carboxy-terminal domain is necessary to prevent the shut
136 ndrogen receptor (AR), ligand binding to the carboxy-terminal domain (LBD) regulates transcriptional
139 f the carboxy terminus of Rad9 and that this carboxy-terminal domain may be a specific requirement fo
141 ranscription activation domain of Gal4p, the carboxy terminal domain of Tcn1p directed strong calcine
143 We have studied the contribution of the carboxy terminal domains of lipid-free apoE isolated fro
146 present data suggesting that the cytoplasmic carboxy-terminal domain of amphiregulin plays an importa
147 s in TNNI2 that are predicted to disrupt the carboxy-terminal domain of an isoform of troponin I (TnI
151 e present the X-ray crystal structure of the carboxy-terminal domain of Brd4 in complex with HPV-16 E
156 specifically interact with the intracellular carboxy-terminal domain of EAAT4 and modulate its glutam
159 ding of activated CheY to FliM displaces the carboxy-terminal domain of FliG (FliGC) from FliM, modul
160 between FMRP and Ca(V)2.2 occurs between the carboxy-terminal domain of FMRP and domains of Ca(V)2.2
163 n of Rad51 by Chk1 or phosphorylation of the carboxy-terminal domain of hBRCA2 by Chk1 or Chk2 plays
164 oint kinases Chk1 and Chk2 phosphorylate the carboxy-terminal domain of hBRCA2, a protein involved in
165 histone variant that is 62% identical to the carboxy-terminal domain of histone H3 [4,5] and that res
166 w, with the use of crystallography, that the carboxy-terminal domain of human Dnmt3L interacts with t
167 owed selective competitive inhibition of the carboxy-terminal domain of human somatic ACE providing e
168 We determined the crystal structure of the carboxy-terminal domain of human SRAP and found that it
169 the amino-terminal domain is more similar to carboxy-terminal domain of I-DmoI and to I-CreI, with in
174 This interaction takes place through the carboxy-terminal domain of Lig4p and is required for Lig
175 ost proteins, and nonrepeat sequences in the carboxy-terminal domain of LigB show only weak interacti
176 onse (UPR) and autophagy in B cells, and the carboxy-terminal domain of LMP1 activates cellular signa
177 lls, the apoptosis required the UPR, and the carboxy-terminal domain of LMP1 blocked this apoptosis.
179 -transferase with the catalytically inactive carboxy-terminal domain of LPL did not activate CT despi
180 -transferase with the catalytically inactive carboxy-terminal domain of LPL that partially blocked LP
181 ruited to origins by an essential, conserved carboxy-terminal domain of Mcm3 that interacts with and
183 ne residues 983 and 985 contained within the carboxy-terminal domain of Mga2p120 are Rsp5p-directed U
185 n1, which directly and selectively binds the carboxy-terminal domain of NR3A through its NPF motifs a
186 nus of Nischarin preferentially binds to the carboxy-terminal domain of PAK1 when the kinase is in it
187 interdomain connector loop (IDCL) and of the carboxy-terminal domain of PCNA in Apn2 binding and foun
191 is model suggested that POA binds within the carboxy-terminal domain of ribosomal protein S1 (RpsA) a
194 The transcriptional cdks phosphorylate the carboxy-terminal domain of RNA polymerase II, facilitati
195 on factor b (P-TEFb) hyperphosphorylates the carboxy-terminal domain of RNA polymerase II, permitting
198 Sub1 influences Spt5 phosphorylation of the carboxy-terminal domain of RNAPII largest subunit by the
199 study described herein demonstrates that the carboxy-terminal domain of RNase E has little structure
202 of the interdomain connector loop and of the carboxy-terminal domain of Saccharomyces cerevisiae prol
206 vitro transcription assays indicate that the carboxy-terminal domain of the alpha subunit (alpha-CTD)
208 the interacting surfaces of MarA and of the carboxy-terminal domain of the alpha subunit of RNAP (al
209 t the Na(+)-K(+)-ATPase, upon binding to the carboxy-terminal domain of the alpha subunit of the chan
210 n between calmodulin and a novel site in the carboxy-terminal domain of the alpha1A subunit of P/Q-ty
212 Slob is a novel protein that binds to the carboxy-terminal domain of the Drosophila Slowpoke (dSlo
213 Slob, a novel protein that binds to the carboxy-terminal domain of the Drosophila Slowpoke (dSlo
217 juxtaposes transcription factor IIH and the carboxy-terminal domain of the largest subunit of Pol II
218 n basal transcription by phosphorylating the carboxy-terminal domain of the largest subunit of RNA po
224 eraction between Ceg1 and the phosphorylated carboxy-terminal domain of the Pol II largest subunit.
225 e for HPV-11 capsid formation, much like the carboxy-terminal domain of the polyomavirus VP1 protein.
228 in dbp5 mutant strains are dependent on the carboxy-terminal domain of the RNA pol II largest subuni
230 binding motifs and instead is similar to the carboxy-terminal domain of the yeast spliceosome protein
231 Models for the binding of the 200-residue carboxy-terminal domain of two mutants of apolipoprotein
235 tion results in premature termination of the carboxy-terminal domain of VIR, resembling McClintock's
236 s one molecule of the Vps protein Vps22, the carboxy-terminal domain of Vps36 and two molecules of Vp
239 stent with a chaperone activity in which the carboxy-terminal domain of YxiN tethers the protein to t
240 ric and heterooligomeric ENaCs, although the carboxy-terminal domains of beta- and gamma-ENaC subunit
241 Dkk domains and chimeric Dkks shows that the carboxy-terminal domains of both Dkks associate with LRP
242 vity assays demonstrate that both amino- and carboxy-terminal domains of BSP contribute to restoratio
245 ion of cells in culture, both the amino- and carboxy-terminal domains of E3L were required for full p
246 arged regions conserved in the J-domains and carboxy-terminal domains of each J-protein class, and ar
249 ilaments possess side arms that comprise the carboxy-terminal domains of neurofilament middle and hea
258 t on preinitiation complex assembly and Ser5 carboxy-terminal domain phosphorylation for optimal asso
259 lling polymerase II (Pol II) recruitment and carboxy-terminal domain phosphorylation on the IL-8 and
260 han does wild-type US28, indicating that the carboxy-terminal domain plays an important role in regul
261 n with an amino-terminal GTPase domain and a carboxy-terminal domain predicted to be embedded in the
263 These include rotation of the amino- and carboxy-terminal domains relative to each other, and a m
266 lation of Raf-1 at serine 338 and within the carboxy-terminal domain, resulting in an electrophoretic
267 erevisiae Arp2/3 complexes bound to the WASp carboxy-terminal domain reveal asymmetric, oblate ellips
269 amino-terminal RNA recognition motif and two carboxy-terminal domains rich in serine-arginine (SR) di
270 the RNA polymerase holoenzyme alpha subunit carboxy-terminal domain (RNAP alphaCTD) and stimulate tr
271 ad2/Smad4/FAST-1 complex to DNA; through its carboxy-terminal domain, Smad4 provides an activation fu
272 the highly exposed alpha-helix 2 of the Smad carboxy-terminal domain specify the interaction with the
275 tions of Int are apportioned between a large carboxy-terminal domain that cleaves and ligates DNA at
276 eceiver domain linked by a small region to a carboxy-terminal domain that contains an amino acid sequ
277 mediated by the human protein TAP requires a carboxy-terminal domain that directly interacts with com
278 bunits, a highly charged inter-region, and a carboxy-terminal domain that encodes a functional PP2C.
280 hogen Pseudomonas syringae pv. tomato, has a carboxy-terminal domain that is an E3 ubiquitin ligase.
281 and p20C/EBPbeta bind to SRF in vitro via a carboxy-terminal domain that probably does not include t
282 of phosphorylation in the amino-terminal and carboxy-terminal domains that are positioned to alloster
283 IcsA is anchored in the outer membrane by a carboxy-terminal domain (the beta domain), such that the
284 at Thr75 is the first residue of the minimal carboxy-terminal domain, thereby identifying a specific
285 of traR, and the resulting protein lacks the carboxy-terminal domain thought to constitute the DNA-bi
286 l as alpharetroviruses by providing critical carboxy-terminal domains to the intasome core that canno
287 and STING interacted directly, through their carboxy-terminal domains, to promote STING dimerization,
288 tructed an HCMV recombinant virus encoding a carboxy-terminal domain truncation mutant of US28, FLAG-
289 mily of traffic ATPases revealed a conserved carboxy-terminal domain unique to family members which a
293 in many chromatin-associated proteins, and a carboxy-terminal domain which identifies it as a member
294 in phosphorylation of the RNA polymerase II carboxy-terminal domain, which in turn affects recruitme
296 n containing the Taxol-binding site, and the carboxy-terminal domain, which probably constitutes the
297 the two Moody proteins differ in their long carboxy-terminal domains, which are generated by use of
298 o-terminal DNA-binding domains but different carboxy-terminal domains, which enable them to bind spec
299 anscripts that encode proteins with modified carboxy-terminal domains, while the mitochondrial isozym
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