ライフサイエンスコーパス: carboxy-terminal region

1 lt in radical physicochemical changes in the carboxy terminal region.

2 nd three in sub-domain VIII), and two in the carboxy terminal region.

3 -turn-helix DNA binding motif located in the carboxy-terminal region.

4 calization signals were mapped to ataxin-7's carboxy-terminal region.

5 two LIM domains with regular spacing in the carboxy-terminal region.

6 half of the enzyme and does not require the carboxy-terminal region.

7 e an amino-terminal region and differ in the carboxy-terminal region.

8 n protease susceptibility in the central and carboxy-terminal regions.

9 to a lesser extent, in both the central and carboxy-terminal regions.

10 ted between structurally distinct amino- and carboxy-terminal regions.

11 domain, as well as conserved motifs in their carboxy-terminal regions.

12 ino acids 2003 to 2212 of CBP, which we call carboxy-terminal region 2 (CR2), as the minimal region f

13 assay, we show that vIRF-1 also targets the carboxy-terminal region (aa 1623 to 2414) of the transcr

14 us in vitro experiments showed that the Cet1 carboxy-terminal region (amino acids 265 to 549) carries

15 minants of antifungal activity reside in the carboxy-terminal region (amino acids 31-45) of MsDef1.

16 d with either full-length mKsr-1 or only its carboxy-terminal region, an inhibition of serum-stimulat

17 e positional homology across species for the carboxy terminal regions and relative positional homolog

18 ember of the TBP family that has a conserved carboxy-terminal region and DNA-binding domain virtually

19 The HAT activity of SRC-1 maps to its carboxy-terminal region and is primarily specific for hi

20 vation domains of both proteins map to their carboxy terminal regions, and we note that the activatio

21 The amino- and carboxy-terminal regions are characterized by several po

22 In contrast, the conserved amino- and carboxy-terminal regions are inactive.

23 (Ser) and one threonine (Thr) residue in the carboxy-terminal region as phosphorylation sites (RRS(23

24 to 299; AD2, aa 300 to 355) were within the carboxy-terminal region, as analyzed by using GAL4:Neuro

25 e central region of epsin binds AP-2 and its carboxy-terminal region binds Eps15.

26 respects, including its catalytic domain and carboxy-terminal region, both of which are essential for

27 homologous to other nuclear receptors in its carboxy-terminal region, but it lacks the characteristic

28 HO) cells of full-length SJ170 or its unique carboxy-terminal region caused mislocalization of Eps15,

29 AS) domain and a PAS-cap domain, whereas the carboxy-terminal region contains a cyclic nucleotide-bin

30 A second, more carboxy-terminal region (domain 2) was identified betwee

31 Despite a high degree of conservation in the carboxy-terminal region (e.g., putative functional domai

32 ng domains and an extensively phosphorylated carboxy-terminal region enriched in repeating Arg-Ser di

33 a truncated TBP protein containing only the carboxy-terminal region failed to induce either the tRNA

34 Here, we sample internal repetitive and carboxy terminal regions from all extant species of the

35 Carboxy-terminal region immunocytochemistry reveals that

36 adherin; beta-catenin and plakoglobin bind a carboxy-terminal region in a mutually exclusive manner,

37 ique amino termini but that contain a common carboxy-terminal region including DNA-binding and ligand

38 tructure demonstrates the mutual exchange of carboxy-terminal regions including BH2 (Bcl-2 homology 2

39 direct binding of cyclic nucleotides in the carboxy-terminal region is allosterically coupled to ope

40 Thus, the carboxy-terminal region is not required for nuclear loca

41 A chimera, in which the carboxy-terminal region (Leu861-COOH) of the Na+,K(+)-AT

42 heir immunoreactivity in both the amino- and carboxy-terminal regions may reflect differences in amyl

43 al sequence of the mature Env, within the SU carboxy-terminal region, near putative receptor binding

44 HIV-1 strain HXB2), which corresponds to the carboxy terminal region of gp120, have been undertaken.

45 ppears to be downregulated by the receptor's carboxy-terminal region of 98 amino acids, a region that

46 d amino acid sequence is homologous with the carboxy-terminal region of a nucleopore complex protein.

47 acid sequence showed 96.8% identity with the carboxy-terminal region of a yeast nucleopore complex pr

48 cleolar (NoLS) localization signals near the carboxy-terminal region of AAP2 (amino acid positions 14

49 nsus motif was also present in the conserved carboxy-terminal region of all type A and B retroviral e

50 The carboxy-terminal region of another, ORF14, which is pred

51 The TULP proteins share a conserved carboxy-terminal region of approximately 200 amino-acid

52 Here we show that the carboxy-terminal region of BRCA2, which interacts direct

53 -associated protein, as interacting with the carboxy-terminal region of c-Myb.

54 In this study, we identify a carboxy-terminal region of CBP (and p300) that strongly

55 rowth inhibitory activity resides within the carboxy-terminal region of CdiA (CdiA-CT), and that CdiI

56 inus, or deletion of regions in the internal carboxy-terminal region of E protein, led to virus atten

57 The intracellular carboxy-terminal region of each subunit contains several

58 The carboxy-terminal region of each toxin was most effective

59 n to form oligomers when introduced into the carboxy-terminal region of gB monomers lacking this doma

60 in-mediated endocytosis and depends upon the carboxy-terminal region of GluR2/3.

61 arities suggest that Bdf1 corresponds to the carboxy-terminal region of higher eukaryotic TAF(II)250

62 ta indicate that sequence differences in the carboxy-terminal region of human and chicken transferrin

63 an E3 ligase substrate adaptor DCAF1 and the carboxy-terminal region of human SAMHD1.

64 activities or interactions specified by the carboxy-terminal region of ICP0 significantly contribute

65 ponsible for the functional integrity of the carboxy-terminal region of IEP86 between amino acids 344

66 The carboxy-terminal region of KCNH channels contains a cycl

67 Our findings provide a function for the carboxy-terminal region of ligase IV and suggest that BR

68 The carboxy-terminal region of LIN-14 contains an unusual ex

69 screen and found an interaction between the carboxy-terminal region of mKsr-1 and mitogen-activated

70 uction of deletion derivatives made from the carboxy-terminal region of Ndk.

71 ing in truncating mutations that deleted the carboxy-terminal region of Notch1 containing negative re

72 an extended alpha-helix from the disordered carboxy-terminal region of nucleoprotein-core links nucl

73 The carboxy-terminal region of P.69 pertactin incorporates a

74 Surprisingly, the remaining carboxy-terminal region of p27kip1 (p27C) actually induc

75 The carboxy-terminal region of p300, which binds to E1A, was

76 g with cellular transcription factors to the carboxy-terminal region of p300.

77 p300 acetylates Lys-382 in the carboxy-terminal region of p53, whereas PCAF acetylates

78 lysis of the PpsR mutants confirmed that the carboxy-terminal region of PpsR (residues 400 to 464) is

79 is physical contact between the 5'SS and the carboxy-terminal region of Prp8 reflects a functional re

80 This interaction required the same carboxy-terminal region of pTRS1 that is necessary to re

81 iated by the effector domain of TC21 and the carboxy-terminal region of RalGDS.

82 While the carboxy-terminal region of S-layer glycoproteins, consis

83 Mutation of the carboxy-terminal region of SM revealed a region that is

84 The carboxy-terminal region of SMRT contains CoRNR box motif

85 y a transcriptional repression domain in the carboxy-terminal region of the Drosophila Ultrabithorax

86 This region includes the carboxy-terminal region of the ectodomain and the predic

87 s indicated a major role for the charge-rich carboxy-terminal region of the endodomain.

88 Here we demonstrate that the carboxy-terminal region of the essential latent antigen,

89 he HCF-1(N) subunit, which associates with a carboxy-terminal region of the HCF-1(C) subunit that is

90 dent difference in sigma3 cleavage rate to a carboxy-terminal region of the ISVP-bound protein.

91 Clones encoding the carboxy-terminal region of the lobster ryanodine recepto

92 ertants of MDelta2 revealed mutations in the carboxy-terminal region of the N protein that compensate

93 est that the main biological function of the carboxy-terminal region of the NS1 protein of influenza

94 helicase ATP-binding site or deletion of the carboxy-terminal region of the protein reduced the abili

95 tein beta-sheet surface, and reorganizes the carboxy-terminal region of the protein to maximize surfa

96 e NDV V protein appears to be located in the carboxy-terminal region of the protein, a region implica

97 tants localized the inhibitory domain to the carboxy-terminal region of the protein.

98 cDNA clones encoding the carboxy-terminal region of the RalGDS protein were isola

99 s that a lipid is covalently attached to the carboxy-terminal region of the S-layer glycoprotein, our

100 ptor binding domain, discrete regions of the carboxy-terminal region of the surface subunit (SU), or

101 everal lines of evidence indicating that the carboxy-terminal region of the tumor suppressor protein

102 more than one instability determinant in the carboxy-terminal region of the wild-type protein, which

103 Sequence analysis revealed that a carboxy-terminal region of this protein, which we have t

104 erpes gestationis sera) and the other in the carboxy-terminal region of this protein.

105 The carboxy-terminal region of TRAFs (the TRAF domain) is re

106 properties of transportin and found that the carboxy-terminal region of transportin could, by itself,

107 3L replication, deletion mutants affecting a carboxy-terminal region of TRS1 that is not required for

108 The basic carboxy-terminal region of U2A' interacts with the RNA s

109 The carboxy-terminal region of UBF is necessary for transcri

110 yrosines found in the bidentate motif in the carboxy-terminal region of V-SEA.

111 We now report that the carboxy-terminal region of Vpr (amino acids 73 to 96) co

112 ct between the GTPase-binding domain and the carboxy-terminal region of WASP proteins.

113 tetratricopeptide repeat (TPR) domain in the carboxy-terminal region of XAP2 was similar to the third

114 Thus, the carboxy-terminal regions of both the SERCA1 and the Na+,

115 ed by shuffling amino-terminal, central, and carboxy-terminal regions of phyB and phyD.

116 reported interaction between the amino- and carboxy-terminal regions of the alpha-subunit.

117 ns or deletions in the amino-terminal or the carboxy-terminal regions of the E protein were generated

118 function, distinct roles for the amino- and carboxy-terminal regions of the ExbD periplasmic domain

119 alyzing mutations that map in the linker and carboxy-terminal regions of the paired domain, and for m

120 Antibodies to the 19-kDa carboxy-terminal region referred to as MSP1(19) inhibit

121 tiana tabacum), the maize proteins contain a carboxy-terminal region related to the inhibitory domain

122 ast two distinct domains: a highly conserved carboxy-terminal region required for binding to the amin

123 6 suggests that it contains (1) a disordered carboxy-terminal region that associates with HCF, Oct-1,

124 erved motifs and an identical 147-amino-acid carboxy-terminal region that contains a 60-amino-acid bH

125 binding and nuclear localization, Rev has a carboxy-terminal region, the activation domain, whose in

126 erminal two-thirds of gpA, separate from the carboxy-terminal region where mutations affecting the pr

127 o acid alignment showed conserved amino- and carboxy-terminal regions which flank a variable region.

128 bic heptad repeats located at the amino- and carboxy-terminal regions which have been proposed to for

129 domains of PDE2, PDE5 and PDE6 as well as a carboxy-terminal region with homology to the catalytic r

130 domains of LIN-14 are dispensable and that a carboxy-terminal region within exons 9 to 13 is necessar