ライフサイエンスコーパス: carboxyl group

1 d moieties of the PS molecule (phosphate and carboxyl groups).

2 trength, and distance from the charge to the carboxyl group.

3 s of the inhibitor are its indole ring and a carboxyl group.

4 d presence or steric accessibility of a free carboxyl group.

5 rom the FBP C(4) hydroxyl group to the Asp83 carboxyl group.

6 Cs due to the altered spatial orientation of carboxyl group.

7 ly unaffected by the ionization state of the carboxyl group.

8 nt tissues through methylation of IAA's free carboxyl group.

9 and Tyr156 co-ordinate the ligand side-chain carboxyl group.

10 ronic resonance of the intrinsically achiral carboxyl group.

11 ween a conserved cysteine and the C-terminal carboxyl group.

12 ing substrate specificity, and orienting the carboxyl group.

13 at this residue cannot be substituted at its carboxyl group.

14 nism was assigned to the dissociation of the carboxyl group.

15 volved in a hydrogen bond with the domain IV carboxyl group.

16 cupied either by a Cl- ion or by a glutamate carboxyl group.

17 residues and the negatively charged alanine carboxyl group.

18 al elucidation of lipid species containing a carboxyl group.

19 quantify the individual species containing a carboxyl group.

20 ly recognizing the protonation status of the carboxyl groups.

21 nctioning to "protect" the proline amino and carboxyl groups.

22 various number of (18)O-atoms to the peptide carboxyl groups.

23 acid for (18)O-labeling of peptides at their carboxyl groups.

24 are incorporated into the peptide C-terminal carboxyl groups.

25 the like-charge ion pair and the C-terminal carboxyl groups.

26 ts in 95-97 atom % incorporation of (18)O at carboxyl groups.

27 cular hydrogen bonding to the propionic acid carboxyl groups.

28 and proton transfer involving the phenol and carboxyl groups.

29 e to steric hindrance between the methyl and carboxyl groups.

30 identate-mononuclear U(IV/VI) complexes with carboxyl groups.

31 takes place for amino acids with C-terminal carboxyl groups.

32 e first oxidized to carbonyl groups, then to carboxyl groups.

33 hogonal cross-linking chemistry specific for carboxyl groups.

34 3 proved to reliably assess deprotonation of carboxyl groups.

35 ncing the sensitivity due to the presence of carboxyl groups.

36 ol) and macrocyclic lactones linking the two carboxyl groups.

37 gels containing different amounts of grafted carboxyl groups (1-10%) was done using quartz crystal mi

38 ure the dynamics of the side chain amide and carboxyl groups, (13)C(gamma/delta), in Escherichia coli

39 ethylaminophenyl (4), 4-nitrophenyl (5), and carboxyl group (6) as substituents at the exocyclic doub

40 ry activity of C4S, whereas reduction of the carboxyl groups abrogated the activity.

41 s H-bonded directly to the hydrate with each carboxyl group accepting two H-bonds at C=O and donating

42 celerated in parallel to the extent that the carboxyl group acquires a second proton (1H(+)).

43 side-chain of residue 42, and the C-terminal carboxyl group, affected paranucleus self-association.

44 Substrates having functionalities such as carboxyl groups, alcohols, or heterocycles in the vicini

45 Incorporation of (18)O into one carboxyl group allows investigation of the symmetry of t

46 Incorporation of (18)O into one carboxyl group allows investigation of the symmetry of t

47 The introduction of carboxyl groups allows covalent conjugation of biologica

48 rmation from primary amines with hydroxyl or carboxyl groups (amino acids), but not from secondary am

49 ree arginines that accommodates the terminal carboxyl group and a dedicated cavity that facilitates b

50 leavage between the lone double bond and the carboxyl group and defining the position of the lone dou

51 oxidative decarboxylation of the side chain carboxyl group and formation of an aldehyde group at the

52 te cleft, in conjunction with the C-terminus carboxyl group and His267 of a partner subunit forms a t

53 g a conjugated tetraene fluorophore near the carboxyl group and natural methylene-interrupted n-3 or

54 -center hydrogen-bonding pattern between the carboxyl group and the phenolic oxygen atom(s).

55 The ASMA ligand features 2 carboxyl groups and an amine function for the coordinati

56 rongly suggest that the reduction of surface carboxyl groups and the redox activity of carbonyl group

57 These data demonstrate that the C4S carboxyl groups and their equatorial orientation but not

58 functionalities such as hydroxyl or multiple carboxyl groups and to distinguish between isomers.

59 led and chemically modified to have terminal carboxyl groups and used as variably sized probes to stu

60 antiradical moieties (catechol, guaiacyl and carboxyl group) and molecular conformation in antioxidat

61 sting the alkyl chain lengths of the pendent carboxyl groups, and preferred conformations were predic

62 hat in tryptic/Lys-C peptides the C-terminal carboxyl group appears to be in a zwitterionic bond with

63 d a fluorescent oxazole (5) having amine and carboxyl groups approximately the same distance apart as

64 tagging strategy, in which metabolites with carboxyl groups are chemically tagged with (15)N-ethanol

65 nable structures are obtained only when both carboxyl groups are ionized.

66 e aqueous-lipid interface, fatty acids whose carboxyl groups are positioned toward the aqueous phase

67 -accommodating pocket, where alpha-amino and carboxyl groups are stabilized by salt bridges, and the

68 additional polar functional group such as a carboxyl group (as in 3x) or a monosaccharide (as in 4x

69 local scrutiny of protonation states of the carboxyl group, as had been suggested by Arg-bound AdiC

70 a complete dissociation of the alpha-hydroxy carboxyl group at pD < 4.

71 polymerization to verify the presence of the carboxyl group at position 1 and the intactness of the i

72 Addition of a carboxyl group at the alpha position of carbocyclic nucl

73 ch was placed in position B26, and the alpha-carboxyl group at the C terminus of the A chain (A26).

74 ituted)benzylpyrimidines (2-11) containing a carboxyl group at the distal end of the 5'-substituent w

75 s, as predicted, deoxycholate bound with its carboxyl group at the entrance of the K path.

76 ion did not result in loss of the position 1 carboxyl group at the reducing end of the polysaccharide

77 linear peptides that contained a free alpha-carboxyl group at their C-termini but remained covalentl

78 Ionisation of carboxyl groups at all tested pH values, and increased b

79 Lack of the amino or carboxyl groups at the alpha-carbon does not prevent the

80 ertion at ~pH 4 driven by the protonation of carboxyl groups at the inserting end of the peptide.

81 bination of readily functionalized amine and carboxyl groups attached to a chiral central core along

82 irs within 3 A, suggesting that at least one carboxyl group bears a proton.

83 thered biotin cofactor to carry an activated carboxyl group between distantly spaced active sites.

84 ly attached biotin as a vector to transfer a carboxyl group between donor and acceptor molecules duri

85 tively, the H2O loss did not derive from the carboxyl group but involved the sulfinyl oxygen, a proto

86 in thiol in cysteine is more acidic than the carboxyl group by 3.1 kcal mol-1.

87 ebactin via PubC-catalyzed activation of the carboxyl group by adenylation, followed by PubC-catalyze

88 lactam in 27 followed by removal of the C(5) carboxyl group by radical decarbonylation gave deformylg

89 e of hydrophobic acetyl groups, carbonyl and carboxyl groups caused a partial disorganization and dep

90 veal a form of gating in which the glutamate carboxyl group closes the pore by mimicking a Cl- ion.

91 prisingly high water affinity of the neutral carboxyl group, comparable to that of the charge-carryin

92 GO chemical properties including C/O ratios, carboxyl group concentrations, and C-C fractions.

93 ng this tag, we demonstrate the detection of carboxyl group containing metabolites in both human seru

94 tter receptors that are activated by various carboxyl-group-containing compounds play a central role

95 The optimal carboxyl group content was determined to be 5%.

96 hydrogen bonds and other interactions of the carboxyl groups contribute over 8 kcal mol(-1) to the st

97 oups in heparin (N-sulfates, O-sulfates, and carboxyl groups) contributed to binding, consistent with

98 ssesses a shortened carbon chain and lacks a carboxyl group, cysteamine displays a catalytic efficien

99 With a high concentration of protons from 12 carboxyl groups decorating every edge of the cube and an

100 ose with high salinity may, in part, control carboxyl-group density on organic carbon surfaces, consi

101 be achieved by permethylation or by specific carboxyl group derivatization with the possibility of di

102 he desired oligosaccharide containing a free carboxyl group derived from CPB was attached to an amino

103 ensing reagents for activation of free alpha-carboxyl groups, despite reports that this chemistry may

104 be incorporated into the peptide C-terminal carboxyl group during enzymatic digestion.

105 the relatively shallow hydrophobic pore; its carboxyl group emerges at the receptor surface and is st

106 e positions of the newly generated amino and carboxyl groups following the 2 steps in the hydrolytic

107 orm HER2-HER3 kinase domain heterodimers and carboxyl group footprinting mass spectrometry, we observ

108 dation of proteins (FPOP), and site-specific carboxyl group footprinting to investigate the HOS of pr

109 line core and the lack of the necessity of a carboxyl group for activity make them an attractive and

110 owed variant conjugation positions and freed carboxyl groups for other potential uses.

111 n by proton-coupled electron transfer to the carboxyl group forming dihydroxymethyl radical intermedi

112 show that the ethylamido derivative of the 5-carboxyl group from 5-carboxy-fluorescein diacetate or f

113 nsferase subunit catalyzes the transfer of a carboxyl group from biotin to acetyl-coenzyme A (acetyl-

114 UVA irradiation removed carboxyl groups from COOH-MWCNT surface while creating o

115 yde group at the carbon next to the original carboxyl group, giving rise to a characteristic product

116 hydrogel based on N-isopropylacrylamide with carboxyl groups grafted to the chains enabled the immobi

117 NaH in THF (i.e., in the presence of a free carboxyl group) has been attributed to the protection of

118 n chain ethers with bis-terminal hydroxyl or carboxyl groups have been synthesized and evaluated for

119 1-19 methylene and bis-terminal hydroxyl and carboxyl groups have been synthesized and evaluated in b

120 ng histidine or arginine residues and a free carboxyl group (His-Ala-Ile, His-Ala-Leu, Ala-His-Leu, A

121 ation by destabilizing the charged substrate carboxyl group in favor of an electrostatically more neu

122 roups and precluded in the absence of a free carboxyl group in His-Ala-Leu amide.

123 in despite the absence of a second conserved carboxyl group in the active site.

124 y line the proton inlet path to an essential carboxyl group in the c-subunit in the proton uptake sit

125 nyl)ethoxy-1,3,2-dioxaphospholane, bearing a carboxyl group in the gamma-position with respect to the

126 the alanine residue clashing with a critical carboxyl group in the gammaC hole but being accommodated

127 These aspartates have their terminal carboxyl group in the pore lumen, which take up much of

128 A free carboxyl group in the product provides versatility for f

129 f a lysine side chain in the peptide and the carboxyl group in the reagent.

130 Here we show that OprD channels require a carboxyl group in the substrate for efficient transport,

131 The contents of the carbonyl and carboxyl groups in a starch molecule therefore indicate

132 Acidic protons from carboxyl groups in both the lignite HA fraction and a sy

133 n peroxide has no effect on the iron binding carboxyl groups in CyaY, allowing the protein to bind ir

134 s of GAX, followed by more moderate PREs for carboxyl groups in homogalacturonan and rhamnogalacturon

135 fers functionalized products with acetyl and carboxyl groups in one step, in good yields, and with sh

136 -exchange kinetics for individual side-chain carboxyl groups in proteins has been achieved in only a

137 are able to markedly lower the pK values of carboxyl groups in proteins.

138 The two most buried carboxyl groups in ribonuclease Sa (RNase Sa) are Asp33

139 ow) insertion peptide] to study the roles of carboxyl groups in transmembrane (TM) peptide insertion.

140 tinct frequencies from cell wall protein and carboxyl groups, indicating that bacterial adhesion occu

141 yclized between their N-terminal amine and a carboxyl group installed at a C-terminal linker sequence

142 Both conformations have the LN-1-255 carboxyl group interacting with Arg-244, yet the remaini

143 the V-shaped pockets, respectively, and the carboxyl group interacts with S(gamma) of C110 by formin

144 The structure revealed that the substrate carboxyl group interacts with the side chains of Arg45,

145 izing a second polymerization to incorporate carboxyl groups into the HEMA PCCA.

146 a K(+)-ionophore, provided that the glycine carboxyl group is appropriately masked.

147 s buried within the protein, and the exposed carboxyl group is bound by a Ser-93-fatty acid carboxyl-

148 Thus, an intact E46 carboxyl group is essential for observation of either in

149 A lysine instead of the usual carboxyl group is in place of the internal proton donor

150 Furthermore, the carboxyl group is involved in binding N-acetyl-l-ornithi

151 the inhibitory compounds is enhanced when a carboxyl group is linked to the alpha-carbon.

152 n tail is buried in the cavity of TL and the carboxyl group is oriented toward the mouth.

153 The carboxyl group is removed by the MccE enzyme, yielding m

154 ontains no abstractable alpha-proton and the carboxyl group is retained in the product.

155 re subpocket that binds to glutamate's alpha-carboxyl group is sensitive to structural change, as sho

156 However, removal of the carboxyl group is the only modification tested that remo

157 results establish that a properly positioned carboxyl group is the sole requirement for autocatalytic

158 to the carboxyltransferase domain, where the carboxyl group is transferred from biotin to pyruvate.

159 coumermycin A1 biosynthesis, the pyrrolyl-2-carboxyl group is transferred from the peptidyl carrier

160 he decarboxylation of the kinetically stable carboxyl groups is proposed.

161 The key structural difference between the carboxyl groups is that Asp33 forms three intramolecular

162 2 activation loop, as measured by changes in carboxyl group labeling, required both dimerization and

163 tem, such as the biphenyl system, and a free carboxyl group leads to highly potent and selective GIVA

164 C) is a heptapeptide with an aspartate alpha-carboxyl group linked to AMP via phosphoramidate bond.

165 robial biomass, possessing a high density of carboxyl groups may be a mechanism by which ordered dolo

166 es formed in enzymatic reactions involved in carboxyl group metabolism.

167 The amplification effect of carboxyl group modified Fe(3)O(4) MNPs of two sizes on S

168 iwalled carbon nanotubes functionalized with carboxyl groups (MWCNTf) was developed to modify glassy

169 the active site of OASS, and its C-terminal carboxyl group occupies the same anion binding pocket as

170 ved structure, this residue interacts with a carboxyl group of 3-hydroxyglutarate, the hydrolysis pro

171 Compound 5b was prepared by coupling the carboxyl group of 3b and the free amino group of arylate

172 )-catalyzed amide bond formation between the carboxyl group of 5caC and a primary amine group.

173 ealing specific hydrogen bonds between the 5-carboxyl group of 5caC and the conserved epi-DNA recogni

174 These findings showed that loss of the carboxyl group of a C18 monounsaturated fatty acid lead

175 residue is enzymatically linked to the gamma-carboxyl group of a glutamate in the primary sequence of

176 of the beta1 subunit of alpha4beta1 and the carboxyl group of Asp-40 of VCAM-1 through the use of si

177 ite in the open form that is occupied by the carboxyl group of Asp-473 in the closed form, it was pro

178 stance, 2.71A; angle, 100 degrees ) with the carboxyl group of Asp79.

179 nto the corresponding 1,3-dioxolanes and the carboxyl group of benzoate ester into an orthoester func

180 d GXGRXG motif is shown to interact with the carboxyl group of biotin and to stabilise the alpha- and

181 the biotin bonds shared an amide link to the carboxyl group of biotin but differed in the chemical li

182 ich coordinate the same oxygen atom of the 4-carboxyl group of CAIR; whereas, the third coordinates t

183 units are formed by attaching glycine to one carboxyl group of cis-1,2-cyclohexanedicarboxylic acid (

184 Although interactions with the carboxyl group of GABA remain unknown, three positively

185 positioned to bestow specificity for the 6''-carboxyl group of GlcNAc(3NH(2))A through a salt bridge.

186 e charge that otherwise would clash with the carboxyl group of Glu-177 of APR.

187 he structure of the L38E variant, the buried carboxyl group of Glu38 interacts with two backbone amid

188 nocoumarin (DECM) was used to cage the gamma-carboxyl group of glutamic acid, which is also a neurotr

189 The alpha-carboxyl group of glycine was covalently coupled to the

190 d to the mineral surface but bonded with the carboxyl group of glyphosate.

191 Unexpectedly, the carboxyl group of H148D is found in a buried position, d

192 rived from the deprotonation of the terminal carboxyl group of MHA).

193 ) was observed, probably stabilized by the 5-carboxyl group of OG, not reported before.

194 a trans double bond introduced close to the carboxyl group of palmitic acid, which is specifically e

195 From this, it can be concluded that the carboxyl group of PEP is responsible for energetic coupl

196 le-strand DNA oligo was immobilized with the carboxyl group of poly(p-aminobenzoic acid) and served a

197 rved enzyme that methyl esterifies the alpha carboxyl group of prenylated proteins including Ras and

198 rgies of binding one solvent molecule to the carboxyl group of SA.

199 Carboxyl group of syn-isomers may also participate in th

200 a hydrogen bond with the oxygen atom of the carboxyl group of the amino acid attached to the A-site

201 The carboxyl group of the bound asparagine makes salt bridge

202 ecules, which hydrate one oxygen atom of the carboxyl group of the glutamic acid.

203 d acid, the initial addition of water to the carboxyl group of the indolecarboxylic acid leads to a h

204 The carboxyl group of the laevulinic acid forms hydrogen bon

205 The preferred site for amidation is the free carboxyl group of the meso-diaminopimelic acid residue.

206 Replacing the carboxyl group of the substrate with a methyl alcohol or

207 rough a phosphoramidate linkage to the alpha-carboxyl group of the terminal aspartate.

208 nother amino acid, or even blocking the free carboxyl group of this arginine residue by amidation, el

209 The carboxyl group of this compound is required in a particu

210 The carboxyl group of this segment was coupled to the N-term

211 se A catalyzes the amide linkage between the carboxyl group of threonine and the amino group of penta

212 ms an amide bond between the BcpA C-terminal carboxyl group of threonine and the side-chain amino gro

213 s the formation of an amide bond between the carboxyl group of threonine at the C-terminal end of pol

214 e and asparagine of the NPQTN motif, and the carboxyl group of threonine is amide-linked to the amino

215 the threonine and glycine residues, and the carboxyl group of threonine is amide-linked to the side

216 and the alanine (A) residue; the C-terminal carboxyl group of threonine is subsequently amide linked

217 Dtx3L/Parp9 ADP-ribosylates the carboxyl group of Ub Gly76.

218 lished that amino acid derivatization of the carboxyl groups of (R,R)-N,N'-phthaloyl-2,3-(2-carboxyph

219 enefited from the reactive functional groups-carboxyl groups of Alb NPs, p19 protein, a viral protein

220 Carboxyl groups of amino acids are reduced to iodomethyl

221 with a few of 10 negatively charged sulfo or carboxyl groups of Arixtra at the interfaces.

222 oups in proteins with the lowest pKs are the carboxyl groups of aspartic acid side-chains.

223 the substrate is primarily anchored by gamma-carboxyl groups of Glu57 and Glu208 at the DOHH active s

224 s-linking by blocking the solvent-accessible carboxyl groups of horseradish peroxidase and alkaline p

225 groups of N-terminal residues but also gamma-carboxyl groups of internal (non-N-terminal) Asp and Glu

226 Using EDC and Sulfo-NHS, terminal carboxyl groups of N-succinyl-Ala-Ala-Pro-Phe p-nitroani

227 ains through the coordination bonds with the carboxyl groups of PAA blocks.

228 The carboxyl groups of PAA brushes can act as reducing moiet

229 tably trapped within the PAA brushes and the carboxyl groups of PAA can serve as internal proton sour

230 covalently conjugated ICG-NH2 to the pendant carboxyl groups of poly (ethylene glycol)-block-poly(2-m

231 se-catalyzed flux of (13)C label between the carboxyl groups of pyruvate and lactate in the tumor can

232 ering the binding sites to interact with the carboxyl groups of templates, were imbedded into MIPs by

233 cium-driven electrostatic interactions among carboxyl groups of the AGPs and the pectic acids give ri

234 To be specific, the richness of carboxyl groups of the CDs enabled strong adsorption of

235 n binding assays indicated that the retained carboxyl groups of the fatty acids helped maintain a tig

236 The ligands of the metal ion are the carboxyl groups of the first and third Asp residues of t

237 The carboxyl groups of the initially PEGylated protein were

238 The carboxyl groups of the PAA graft could be derivatized to

239 ment (coccolith vesicle) through the charged carboxyl groups of their uronic acid residues.

240 ell as from the neutralization of the native carboxyl groups of thin-film composite polyamide membran

241 It is found that both the ammonium and carboxyl groups offer good water binding sites with bind

242 However, one enzyme's free carboxyl groups often react with another's free amino gr

243 cetyl-l-ornithine (PALAO) indicates that the carboxyl group on Lys302 forms a strong hydrogen bonding

244 We also show that the carboxyl group on nonreducing end glucuronic acid in dod

245 eractions between active site residues and a carboxyl group on the Pchlide molecule result in a polar

246 this study demonstrate that the presence of carboxyl groups on ENPs and divalent ions in the solutio

247 elimination of calcium bridging between the carboxyl groups on MWNTs and silanol groups on silica su

248 f stoichiometric Pdr-Pdx complexes only when carboxyl groups on Pdx were activated.

249 analogues bearing hydroxyl, amino, amido, or carboxyl groups on the azabicyclic ring.

250 via diimide-activated amidation between the carboxyl groups on the CNT surface and amine groups on t

251 -1,2-ethandiyl (PCBS), resulting in terminal carboxyl groups on the LPG-ISAM.

252 w protons to gain access to and leave buried carboxyl groups on the proteolipid subunits (c, c', and

253 , Pro, and His differ, as does the number of carboxyl groups on the respective surfaces, whereas the

254 Electrochemically formed carboxyl groups on the surface of the graphite were cros

255 The carboxyl groups on the surface of the modified barley st

256 ca-coated UCNPs (50 nm in diameter) exposing carboxyl groups on the surface were conjugated to a seco

257 to host up to three water molecules and the carboxyl group one water molecule before additional wate

258 stalled by cyclization of the pentenoic acid carboxyl group onto the vinyl epoxide in an S(N)2' fashi

259 substrate for lactonization, by allowing the carboxyl group oxygen to approach more closely the methy

260 yl-aliphatic ketones, aliphatic and aromatic carboxyl groups, phenol, and methoxy phenyl ethers.

261 latform for the DNA-c by the large number of carboxyl groups present on the functionalized gold nanop

262 t a LPMO (from Neurospora crassa) introduces carboxyl groups primarily in surface-exposed crystalline

263 nique Zn2+ coordination via two thiols and a carboxyl group provides selective binding of the activat

264 ydrogen bonding between pairs of neighboring carboxyl groups, reduces the root mean square error at t

265 ly bound to MBs functionalized with amine or carboxyl groups, respectively.

266 lysis suggests that mechanisms involving two carboxyl groups result in the most stable bond to the mi

267 e of a gamma-ketone relative to the terminal carboxyl group resulted in C-C bond cleavages along the

268 nucleophilic attack on the phosphorus by the carboxyl group resulting in the spontaneous elimination

269 Exposed carboxyl groups seem to favor the direct route of elimin

270 Similarly, the BE of carboxyl groups shifted approximately -1.3 eV upon depro

271 The pK(a)s of the carboxyl groups studied vary significantly but all are l

272 provided a high content of surface confined carboxyl groups suitable for direct covalent binding of

273 ks) involve binding to two oxygen atoms from carboxyl groups (the most superficial binding peak) or t

274 are complexed and dewatered by surface-bound carboxyl groups, thus decreasing the energy required for

275 A mechanism involving oxidation of the carboxyl group to a carboxylic radical followed by addit

276 iate involves early proton transfer from the carboxyl group to water along with C-C bond cleavage, pr

277 on 1 in water showed the pK(a)'s of the two carboxyl groups to be similar (average 6.42).

278 CNTs used in our studies were derivatized by carboxyl groups to facilitate their dispersion in water.

279 such as the N terminus; (ii) converting the carboxyl groups to the active ester of N-hydroxysuccinim

280 al enzymes carry out metabolically important carboxyl group transfer reactions and are potential targ

281 Helix stabilization requires the protonated carboxyl group; unexpectedly, this stabilization could n

282 was efficiently converted into the required carboxyl group via conventional transformations.

283 e systems, and in these, the position of the carboxyl group was extended from the ligand core, either

284 A water-soluble conjugate (1) with intact carboxyl groups was prepared by addition of poly(ethylen

285 The terminal carboxyl groups were covalently conjugated to monoclonal

286 roparticles functionalized homogenously with carboxyl groups were generated using stop-flow lithograp

287 Qdots with exposed carboxyl groups were readily taken up by synaptic vesicl

288 These carboxyl groups were utilized to achieve variable degree

289 purpose as the proton can be carried on the carboxyl group, whereas the basicity of the tropylium io

290 leobase recognition involving the C-terminal carboxyl group, which is only required in the reverse re

291 luorescein diacetate, still possesses a free carboxyl group whose ionization constant is such that th

292 Other derivatives with modification of the 5-carboxyl group with an ester group or with a thiourea-ba

293 cine buffer molecule which interacts via its carboxyl group with conserved active site residues S130,

294 A derivatives obtained by conjugation of its carboxyl group with different alpha-amino acids.

295 he pilin C terminus, the blocking of the Ser carboxyl group with the addition of an Ala prevented gly

296 Through reaction of the carboxyl groups with (+)-biotinyl-3,6,9,-trioxaundecaned

297 Cloaking its carboxyl groups with a hydrophobic moiety is shown to en

298 Observations support the deprotonation of carboxyl groups with low acid dissociation constants (pK

299 ng domain has an unusually high affinity for carboxyl groups, with KD at approximately 100 microM.

300 suggest that the pK values for these buried carboxyl groups would be greater than 8 in the absence o