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1 rs, anti-1-amino-3-(18)F-fluorocyclobutane-1-carboxylic acid ((18)F-FACBC or (18)F-fluciclovine) has
2 (18)F-labeled 1-amino-3-fluorocyclobutane-1-carboxylic acid ((18)F-fluciclovine) is a leucine analog
3 by (2S,4R)-4-(2-carboxyphenoxy)pyrrolidine-2-carboxylic acid (1b), for cloned homomeric kainic acid r
4 )-5-ethyl-1,6-dihydroxycyclohexa-2,4-diene-1-carboxylic acid (4) into compound 3, the latter being a
5 oughout the colony, with 5-methylphenazine-1-carboxylic acid (5-MCA) and pyocyanin (PYO) localized to
7 of this regulation is 1-aminocyclopropane-1-carboxylic acid (ACC) synthases (ACS), generally the rat
9 enosyl-L-methionine to 1-aminocyclopropane-1-carboxylic acid (ACC)] and PsACO (encode enzymes that co
10 no-2-carboxyethyl]-4,5-dihydro-1H-pyrazole-3-carboxylic acid (ACEPC) competitive GluN2 antagonists, o
11 ures show that vegetable-sourced azetidine-2-carboxylic acid (Aze), a dual mimic of proline and alani
12 -methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (BQCA) (1), but markedly improved positi
13 restored by treatment with benzyl quinolone carboxylic acid (BQCA) and benzoquinazoline-12 (BQZ-12),
14 sensitivity to functional group addition is carboxylic acid (COOH) approximately hydroxyl (OH) > nit
15 eophilic groups on Wnt proteins to activated carboxylic acid (COOH) or glutaraldehyde (COH) groups fu
16 )-1-methyl-4-nitro-3,5-diphenylpyrrolidine-2-carboxylic acid (endo-6) and (2S,3S,4R,5S)-1-methyl-4-ni
17 )-1-methyl-4-nitro-3,5-diphenylpyrrolidine-2-carboxylic acid (exo-6), combined with 1,8-diazabicyclo[
18 ctors was primarily due to 5:3 fluorotelomer carboxylic acid (FTCA - 3.9 nmol/L) and perfluorohexanoi
19 landfill leachate samples, 5:3 fluorotelomer carboxylic acid (FTCA) was dominant and variations in co
20 oduction reveals distribution of phenazine-1-carboxylic acid (PCA) throughout the colony, with 5-meth
22 ell lines depend on glutamine as a major tri-carboxylic acid (TCA) cycle anaplerotic substrate to sup
23 ion of 3-((furan-2-ylmethyl)amino)pyridine-4-carboxylic acid 34 and 3-(((3-methylthiophen-2-yl)methyl
24 -methylthiophen-2-yl)methyl)amino)pyridine-4-carboxylic acid 39 that are inhibitors of the KDM4 (JMJD
25 erivative cis-2-(carboxymethyl)cyclohexane-1-carboxylic acid [(1R,2R)-/(1S,2S)-2-(carboxymethyl)cyclo
26 ) and measured contents of FBPs (pyrrolidone carboxylic acid [PCA] and urocanic acid [UCA]) using UPL
28 ) and P(2-MeOPh)3 (2 mol%), sterically tuned carboxylic acid additives, and an environmentally friend
32 r, KAHA, KATs, etc.) that could involve both carboxylic acid and amine surrogates are treated separat
36 catalysis, to extract carbon dioxide from a carboxylic acid and economically replace it with an orga
37 nantiomers of 2-amino-3-hydroxycyclobutane-1-carboxylic acid and of 2-amino-4-hydroxycyclobutanecarbo
38 unctional groups in these molecules, such as carboxylic acid and phenol moieties, become deprotonated
40 iscovery of 2-acylaminocycloalkylthiophene-3-carboxylic acid arylamides (AACTs) as inhibitors of TMEM
41 sive polymers classified as polyacids (e.g., carboxylic acid based polymers, sulfonamides, anionic po
42 surfaces by pre-attaching probe molecules to carboxylic acid bearing termonomers of pyrrole phenylene
43 tion approach, is especially useful in rapid carboxylic acid carbon isotope labeling, however develop
44 y of Ascaris eggs as a function of uncharged carboxylic acid concentration for n-butyric acid and n-c
47 y have described highly potent and selective carboxylic acid containing MMP-13 inhibitors; however, n
48 f the beta2AR bound to a polyethylene glycol-carboxylic acid derivative (Cmpd-15PA) of this modulator
49 ve the decarboxylative coupling of aliphatic carboxylic acid derivatives (specifically, readily avail
50 akin-West reaction of advanced pyrrolidine 2-carboxylic acid derivatives that can be assembled stereo
51 kyl-5-aryl/alkyl/methoxycarbonyl-1H-pyrrol-3-carboxylic acid derivatives typically under mild conditi
52 ivated enamides, known as the least reactive carboxylic acid derivatives, toward alkylation with orga
55 se inhibitor and 4-amino-tetrahydropyranyl-4-carboxylic acid derived dipeptide GSK-2793660, which is
56 two bioactive peptides: 2-aminoadamantane-2-carboxylic acid derived P2X7-evoked glutamate release in
57 res a scalable classical resolution of tetra-carboxylic acid enantiomers with recycling of the resolv
58 est alkyl chain, -(CH2)2-, and a hydrophilic carboxylic acid end group are found to be the most effec
61 ), titanium dioxide nanofibers (TiO2NFs) and carboxylic acid functionalized multi-walled carbon nanot
63 ins are folded in a hairpin manner near each carboxylic acid group, giving rise to multiple embedded
64 by probing the vibrational signatures of the carboxylic acid group, representing the nondissociated a
66 itive case of a hydrogel containing multiple carboxylic acid groups at each crosslinking point in the
68 sorbent coating featuring halide anions and carboxylic acid groups in the cationic portion exhibited
70 precise linear architecture, namely, pendant carboxylic acid groups precisely every 21st backbone car
71 to the porphyrin and proton transfer from a carboxylic acid hanging group or an external acid to the
73 bly between a phosphoric acid catalyst and a carboxylic acid has recently been established as a new a
74 ogenous phenazines pyocyanin and phenazine-1-carboxylic acid in both cytosolic and membrane fractions
75 ctional groups on the beta-carbon (e.g., the carboxylic acid in glycine) that facilitate carbon-carbo
77 ate-stage C-H functionalization converting a carboxylic acid into a lactone through the oxidation of
78 ovel and efficient method for alkyl and aryl carboxylic acid isotopic labeling using a single reagent
79 otency and pharmacokinetic properties of non-carboxylic acid leads resulting in the identification of
80 is due to the presence of negatively charged carboxylic acid moieties from PAA grafts that electrosta
81 ed SPME sorbent coatings, the PIL containing carboxylic acid moieties in the monomer and halide-based
82 a known azetidine FFA2 antagonist, we used a carboxylic acid moiety known not to be critical for rece
83 icyclic nortropine-substituted benzothiazole carboxylic acid moiety onto a trisubstituted isoxazole s
86 essing the activity of 1-aminocyclopropane-1-carboxylic acid oxidase (ACO), the enzyme catalysing the
88 .g., with no pre- or in situ activation of a carboxylic acid partner) approaches for the construction
90 s by methylation of alcohol, thiol, amine or carboxylic acid precursors using [(11)C]methyl iodide or
91 o]phenyl]-5-(trifluoromethyl)-1H-p yrazole-4-carboxylic acid prevents AIAD in mice, (2) TRPC3 channel
92 adenylation of substrates, amidation of the carboxylic acid proceeds by direct reaction of the acyl
93 peroxide anion 7' to afford the aldehyde-to-carboxylic acid product or as a hydroperoxy derivative 7
96 hat differ in the relative position of their carboxylic acid recognition site: either para (M(p)) or
98 aratus of BT3686 does not comprise a pair of carboxylic acid residues but, uniquely, a single histidi
102 uction and expression of aminocyclopropane-1-carboxylic acid synthase gene, the first committed step
103 atic system by coordination of an amine or a carboxylic acid to the boron center enabled N-H activati
104 N-hydroxyphthalimide ester derivative of the carboxylic acid under visible light at room temperature
107 (MNPs) coated with poly(pyrrole-co-pyrrole-2-carboxylic acid) (Py/Py-COOH) for high efficient detecti
108 l-5 -yl)-[1,1'-biphenyl]-4-yl)cyclopropane-1-carboxylic acid) in rhesus monkeys to image LPA1 in the
109 (2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid) is a metabolite that circulates at high
110 e (LND; 1-(2,4-dichlorobenzyl)-1H-indazole-3-carboxylic acid) is known to interfere with energy-yield
111 (primary alcohol, phenol, vicinal diol, and carboxylic acid), ranging in complexity from methanol to
112 tetramers) of cis-2-(aminomethyl)cyclobutane carboxylic acid, a gamma-amino acid featuring a cyclobut
113 4,5-dihydroxy-2,3,4,5-tetrahydropyridazine-3-carboxylic acid, a gamma-halogenated piperazic acid, and
116 Cross-metathesis with olefins that contain a carboxylic acid, an aldehyde, an allylic alcohol, an ary
117 oduced by oxidation of 1-aminocyclopropane-1-carboxylic acid, as catalyzed by 1-aminocyclopropane-1-c
118 h analogues of varying ring sizes (azetidine carboxylic acid, Aze, and piperidine carboxylic acid, Pi
119 an, but not 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid, competitively inhibited (11)C-sarcosine
120 an optical pH indicator, SNARF-5F, 5-(and-6)-Carboxylic Acid, encapsulated into polyacrylamide nanopa
121 -methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, enhanced acetylcholine-mediated phospho
122 c(NN) is 2-amino-5-nitronylnitroxide-indan-2-carboxylic acid, have been inserted at positions i and i
124 diazole and alpha,alpha-dimethylation of the carboxylic acid, improving DGAT1 potency and gut permeab
125 pH2cH = 2,2'-bipyridine-6-phosphonic acid-6'-carboxylic acid, L = 4-picoline or isoquinoline) catalys
126 N bond to release the corresponding alcohol, carboxylic acid, or amine when an electron-donating amin
128 etidine carboxylic acid, Aze, and piperidine carboxylic acid, Pip) to produce different trans/cis rat
129 ,6,6-tetramethyl-piperidine-1-oxyl-4-amino-4-carboxylic acid, the probe is rigidly and stereospecific
130 nated PAMAM dendrimers, we confirm safety of carboxylic acid- and pyrrolidone-terminated PAMAM dendri
131 rther, we report the first example of a free carboxylic acid-directed Pd(II)-catalyzed C(sp(3))-H bro
132 sor design involves disposable devices using carboxylic acid-functionalized magnetic microparticles s
140 (DA) is used to convert the TAT's amines to carboxylic acid; the resulting DA-TAT is conjugated to p
141 ,2R)-/(1S,2S)-2-(carboxymethyl)cyclohexane-1-carboxylic acid] has previously been identified as metab
142 atile fraction mainly contains esters (38%), carboxylic acids (19%), aldehydes (11%), alcohols (14%),
143 e, 1 [Ga(tpfc)], with either sulfonic (2) or carboxylic acids (3, 4) as macrocyclic ring substituents
144 (hexanal, pentenal, nonanal and nonenal) and carboxylic acids (9-oxononanoic acid, octanoic acid, non
145 be system based on 4'-substituted biphenyl-2-carboxylic acids (BPAs) for analysis of photooxidants ge
146 acids (PFSAs; C4,6,8,10) and perfluoroalkyl carboxylic acids (PFCAs; C6-15) along with six perfluoro
147 lexes that specifically respond to amines or carboxylic acids - two classes of semiochemicals that ha
150 produces polyfunctional low molecular weight carboxylic acids after oxidative cleavage of the aromati
151 tones were the most efficient stimuli, while carboxylic acids and aliphatics/aromatics were comparati
153 ation of sp(3)-sp(3) bonds using only simple carboxylic acids and alkyl halides as the nucleophilic a
154 m of the zirconium-catalyzed condensation of carboxylic acids and amines for direct formation of amid
155 AD(P)(+)-dependent oxidation of aldehydes to carboxylic acids and are important for metabolism and de
157 to amino acids, peptides and carbohydrates, carboxylic acids and compatible solutes may be essential
158 investigated linear peroxy acids but not for carboxylic acids and could therefore serve as a diagnost
159 essible through reactions between ubiquitous carboxylic acids and coupling agents widely used in amid
166 ylates from Se/LiEt3BH and acyl chlorides or carboxylic acids and their reaction with sugar azides.
168 how that low molecular weight and oligomeric carboxylic acids are kinetically equivalent at accelerat
173 ionalization of the beta-C(sp(3))-H bonds of carboxylic acids are well documented, but only a few rep
176 on of primary, secondary, and tertiary alkyl carboxylic acids as well as a diverse range of natural-p
178 her and also from sulfonamides and aliphatic carboxylic acids based on reactions with TMMS and one or
179 for constructing amide bonds join amines and carboxylic acids by dehydrative couplings-processes that
180 hnique for selective fluorination of various carboxylic acids by exposure to gaseous sulfur tetrafluo
181 phoresis, as well as the separation of small carboxylic acids by gradient elution moving boundary ele
184 of judicious catalyst design, the acidity of carboxylic acids can be modulated, for instance by stabi
185 pH/proton concentration and the structure of carboxylic acids contribute to sour GRN activation.
190 , while in biochar was featured by saturated carboxylic acids from hemi/cellulose and lipids with con
192 ediated cleavage of ketones into alkanes and carboxylic acids has been reinvestigated and the substra
194 dicate that in situ biological production of carboxylic acids in HFM provides a promising method of p
195 To fill this gap, we measured gas-phase carboxylic acids in real-time inside and outside of a un
196 les-derived from Fukuyama amines-and peptide carboxylic acids in Ugi and Passerini reactions to affor
198 is a classic, powerful method for converting carboxylic acids into protected amines, but its widespre
200 erminal and substituted alkynes from various carboxylic acids is described using both nickel- and iro
205 etathesis of silylated alkynes with aromatic carboxylic acids on the Ag(111) and Au(111) surfaces to
206 able N-substituted amides or their requisite carboxylic acids or acid chlorides have been used to con
207 nd with the acceptor groups varied as either carboxylic acids or benzoic acids on the pi-bridge.
209 d donors and chiral phosphoric acids, chiral carboxylic acids provide the opportunity to activate a d
210 mistry has been developed for aryl and alkyl carboxylic acids respectively with two rationally design
211 posing oleate-capped quantum dots to primary carboxylic acids results in a one-for-one exchange that
213 ) catalyze the reduction of a broad range of carboxylic acids to aldehydes using the cofactors adenos
215 catalyzed coupling of alpha,beta-unsaturated carboxylic acids to aryl alkenes to access chiral alpha-
217 n the regioselective Markovnikov addition of carboxylic acids to terminal alkynes, yielding valuable
218 ect conversion of arylacetic acids into aryl carboxylic acids under metal-free conditions has been de
219 carbons and the Schmidt reaction of aromatic carboxylic acids using the superacidic trimethylsilyl az
220 ns from a variety of benzoisothiazolones and carboxylic acids using triethylphosphite as the terminal
221 step-economic alpha,beta-dehydrogenation of carboxylic acids via enediolates is reported through the
224 ighest number of carbohydrates, polymers and carboxylic acids were consumed in the SF sourdough.
227 al light-induced decarboxylative coupling of carboxylic acids with (hetero)aromatic nitriles at ambie
228 that enables chemists to couple simple alkyl carboxylic acids with aryl zinc reagents under Ni-cataly
229 ng of primary, secondary, and tertiary alkyl carboxylic acids with both aryl and heteroaryl organomet
230 zed decarboxylative coupling of heterocyclic carboxylic acids with heterocyclic halides to achieve th
231 ecades to make simple C-N (amide) bonds from carboxylic acids with loss of water can be used to make
233 ters (both isolated and derived in situ from carboxylic acids) with organozinc and organomagnesium sp
234 amides, (2) hydrolysis of N-methoxyamides to carboxylic acids, (3) metal- and oxidant-free benzocouma
236 t added acid due to the in situ formation of carboxylic acids, accounting for the long-known catalyti
238 rbonyl radiopharmaceuticals based on labeled carboxylic acids, amides, carbamates and ureas now accou
239 ere readily converted into primary alcohols, carboxylic acids, amides, isocyanates, and carbamates, a
240 is fast at acidic pH and tolerates alcohols, carboxylic acids, and even secondary amines in the subst
241 mposition routes for furanoids and aliphatic carboxylic acids, and mechanistic pathways for the radio
242 clopentylation" of amines, alcohols, thiols, carboxylic acids, and other heteroatoms is introduced.
243 the one-pot preparation of alpha-quaternary carboxylic acids, esters, and amides with a high degree
245 ne-pot synthesis of thioesters directly from carboxylic acids, N,N'-diphenylthiourea, triethylamine,
249 tor has been employed for the methylation of carboxylic acids, the synthesis of alpha-chloro ketones
250 s well as a diverse range of natural-product carboxylic acids, thereby demonstrating its broad utilit
251 divergent resolution of racemic alpha-chiral carboxylic acids, thus providing access to a variety of
252 compounds were transformed to perfluorinated carboxylic acids, which underwent further degradation un
253 four metal-binding sites in the form of four carboxylic acids, while zirconyl chloride octahydrate is
254 rovided good yields of nitrile products from carboxylic acids, with complete retention of isotopic pu
277 a sour GRN that is specifically activated by carboxylic and mineral acids but does not respond to swe
278 ionality of biochar with the introduction of carboxylic and phenolic groups, a reduction of oxonium g
280 electrochemical method for the synthesis of carboxylic as well as hindered esters from N-alkoxyamide
281 promoted stabilization of aliphatic C-H and carboxylic C=O compounds associated with mineral phases.
282 process with the aryl azides and alpha-diazo carboxylic esters serving as precursors for nitrogen and
285 showed no such behavior, thus the additional carboxylic group should be responsible for the observed
288 ich recognized interaction of phosphonic and carboxylic groups as decisive in phosphonocarboxylate lo
289 rbomethoxy groups were deprotected to obtain carboxylic groups used to immobilise antibodies for card
293 mine molecules appended with crown-ethers or carboxylic moieties form self-assembled supramolecular c
294 where embedding the amide group between two carboxylic moieties in proper geometries, at distances l
296 nt on the molecular functionality (i.e., the carboxylic or OH functional group in organic acids and m
298 y nature, such as dissolved black carbon and carboxylic-rich alicyclic molecules, was also rapidly an
300 timal relation of pyrrole and pyrrole-3-acid carboxylic to perform the cTnT biomimetic nanosurface wa
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