ライフサイエンスコーパス: carboxymethyl

1 vatives, with the (64)Cu complex of 4,10-bis(carboxymethyl)-1,4,7,10-tetraazabicyclo[5.5.2]tetradecan

2 , CREKA-Tris(Gd-DOTA)3 (Gd-DOTA (4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecyl gadolinium)

3 carboxylic acid) (CB-TE1A1P) and 2-(4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl)pentanedioic acid (N

4 gh-affinity PET probe, (64)Cu-labeled 11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2] hexadecan

5 cular LLP2A format using (64)Cu-LLP2A-11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

6 synthesis and evaluation of 64Cu-CB-4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

7 CBTE2A (CBTE2A is 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

8 bes the radiolabeling procedure for 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

9 o, whereas 64Cu-CB-TE2A (CB-TE2A is 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

10 cross-bridged macrocyclic chelator 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

11 revealed that the (64)Cu complex of 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

12 ee 4,11-di-pendant arm derivatives: 4,11-bis(carboxymethyl)-1,4,8,11-tetraazabicyclo[6.6.2]hexadecane

13 -deoxy-3-pyridyldimethylglyoximatocobalt-5-O-carboxymethyl-1,2-O-isop ropylidene-alpha-D-xylofuranose

14 s is based on the presence of 2-amino-3-{[2-(carboxymethyl)-2,5-dihydroxy-1-cyclohex-3-enyl]sulfanyl}

15 , 4-oxalocrotonate tautomerase (4-OT) and 5-(carboxymethyl)-2-hydroxymuconate isomerase (CHMI), and c

16 d by 4-oxalocrotonate tautomerase (4-OT), 5-(carboxymethyl)-2-hydroxymuconate isomerase (CHMI), and m

17 The 2-indolamide (52) and N-(carboxymethyl)-2-indolamide (54) derivatives had improve

18 me, the chemical syntheses of authentic N(6)-carboxymethyl-2'-deoxyadenosine (N(6)-CMdA) and N(4)-car

19 thyl-2'-deoxyguanosine (O(6)-MedG), and N(6)-carboxymethyl-2'-deoxyadenosine (N(6)-CMdA).

20 ethyl-2'-deoxyadenosine (N(6)-CMdA) and N(4)-carboxymethyl-2'-deoxycytidine (N(4)-CMdC), liquid chrom

21 thyl)-2'-deoxyguanosine (N(2)-CEdG) and N(2)-carboxymethyl-2'-deoxyguanosine (N(2)-CMdG) sites.

22 for the simultaneous quantification of O(6)-carboxymethyl-2'-deoxyguanosine (O(6)-CMdG), O(6)-methyl

23 The O(6)-carboxymethyl-2'-deoxyguanosine was previously detected

24 es 4-oxalocrotonate tautomerase (4-OT) and 5-carboxymethyl-2-hydroxymuconate isomerase (CHMI).

25 enzymes (4-oxalocrotonate tautomerase and 5-carboxymethyl-2-hydroxymuconate isomerase) that otherwis

26 those of 4-oxalocrotonate tautomerase and 5-carboxymethyl-2-hydroxymuconate isomerase.

27 reference of the enzyme for cyclocreatine (1-carboxymethyl-2-iminoimidazolidine).

28 N-(alpha-methyl-2-nitrobenzyl)urea, N-(alpha-carboxymethyl-2-nitrobenzyl)urea, and N-(alpha-carboxy-2

29 or 5'-O-(dimethoxytrityl) derivatives of 3'-(carboxymethyl)-3'-deoxyribonucleosides that are effectiv

30 The synthesis of 1-(carboxymethyl)-3-(mercaptododecyl)-imidazoliumbromide, a

31 lting alkene gave stereodefined access to 3-(carboxymethyl)-3-deoxy-D-ribofuranose derivatives.

32 18S,21S,24S,27S,30S)-27-(2-carboxyethyl)-21-(carboxymethyl)-30-((2S,3R,4R,5R,6S) -6-((2-(4-(3-F18-flu

33 ometry of quiescent cells and by 2'-7'-bis[2-carboxymethyl]-5(6)-carboxyfluorescein fluorescence meas

34 Gly-His-Sta-Leu-NH2], and NODA-MPAA is 2-[4-(carboxymethyl)-7-{[4-(carboxymethyl)phenyl]methyl}-1,4,7

35 -N'-(2-ethyloxyethyl)-N,N'-bis[N' ',N' '-bis(carboxymethyl)acetamido]-1,2-ethanediamine (ABE-DTTA), h

36 S-(Carboxymethyl)-alpha-lactalbumin, a disordered form of t

37 g on fibrillation of four proteins, bovine S-carboxymethyl-alpha-lactalbumin (a disordered form of th

38 e development of LDTPA (N,N-bis[2-[N',N'-bis(carboxymethyl)amino]- ethyl]-4-amino-L-phenyl-alanine).

39 d ureA DNA fragments by tethering (S)-1{[bis(carboxymethyl)amino]methyl}-2-{4-[(2-bromoacetyl)amino]p

40 eases with (2- inverted question markC2-bis-(carboxymethyl)-amino-5 methylphenoxy]methyl inverted que

41 , 1-{2-[2-[(2-(biscarboxymethyl-amino)ethyl)-carboxymethyl-amino]ethyl]-carb oxymethyl-amino}-acetyla

42 hylamino)-octyl ester (TMB-8) and 2-[(2-bis-[carboxymethyl]amino-5-methylphenoxy)-methyl]-6-methoxy-8

43 thyl inverted question mark-6-methoxy-8-bis-(carboxymethyl)-aminoquinoline tetra-(acetoxymethyl)ester

44 no-5-methylphenoxy)-methyl]-6-methoxy-8-bis [carboxymethyl]aminoquinoline (Quin-2).

45 gregation of Cyanine-1dye in the presence of carboxymethyl amylose (CMA) is described.

46 erformed single-molecule AFM measurements on carboxymethyl amylose, and we found that, in contrast to

47 he gold WEs through functionalization with 4-carboxymethyl aryl diazonium (CMA).

48 lted in excellent yields of anilines; even 2-carboxymethyl aryl nonaflate is effectively coupled with

49 The synthetic derivative of ascochlorin, 4-O-carboxymethyl ascochlorin (AS-6) is an agonist of the nu

50 With an alternative nucleotide, 1-carboxymethyl-ATP, coupled with a mutation that introduc

51 The distribution coefficients for carboxymethyl-beta-cyclodextrin (CM-beta-CD), degree of

52 The addition of carboxymethyl-beta-cyclodextrin in the running buffer as

53 The anionic carboxymethyl-beta-cyclodextrin, used to chromatographic

54 e negatively charged pseudostationary phase, carboxymethyl-beta-cyclodextrin.

55 imetic compound, 2-(trimethylsilyl)ethyl 3-O-carboxymethyl-beta-D-galactopyranosyl-(1-->4)-[alpha-L-f

56 The nitrosated carboxymethyl-bovine serum albumin exhibited similar vas

57 with acidified NaNO2 was compared to that of carboxymethyl-bovine serum albumin in which the thiol gr

58 indicated that a non-cysteine residue(s) in carboxymethyl-bovine serum albumin was nitrosated.

59 NaHCO3, and the (63)Zn was then trapped on a carboxymethyl cartridge, washed with water, and eluted w

60 racellular protein and a 20-fold increase in carboxymethyl cellulase activity relative to a wild-type

61 lZ represents approximately 95% of the total carboxymethyl cellulase activity.

62 to bind to cellulose and an apparent loss of carboxymethyl cellulase and mannanase activities.

63 e largest, with known activities comprising (carboxymethyl)cellulases, mixed-linkage endo-glucanases,

64 , R237, K259 and E263) increased activity on carboxymethyl cellulose (CM-cellulose), with K259H (in g

65 l animals were treated daily with 1 ml of 2% carboxymethyl cellulose (CMC) alone or containing one of

66 ne and of combinations of both enzymes using carboxymethyl cellulose (CMC) and amorphous cellulose (a

67 (MC), hydroxypropyl methylcellulose (HPMC), carboxymethyl cellulose (CMC) and chitosan (CH) coatings

68 FeS) nanoparticles were prepared with sodium carboxymethyl cellulose (CMC) as a stabilizer, and teste

69 Microcrystalline cellulose (MCC) or carboxymethyl cellulose (CMC) can be used as fat replace

70 Nano-ZnO in combination with carboxymethyl cellulose (CMC) coating was used on pomegr

71 The effects of dithionite and nZVI loadings, carboxymethyl cellulose (CMC) coating, addition of palla

72 a low adhesion to MB-thermally cross-linked carboxymethyl cellulose (CMC) film.

73 aterial consisting of commercially available carboxymethyl cellulose (CMC) was evaluated as sampling

74 scale zerovalent iron (nZVI) stabilized with carboxymethyl cellulose (CMC) was performed at an active

75 les employed were either bare or coated with carboxymethyl cellulose (CMC), a polymer utilized to sta

76 zymes were assayed for catalytic activity on carboxymethyl cellulose (CMC), swollen cellulose (SC), f

77 horoughly characterized solutions containing carboxymethyl cellulose (CMC)-stabilized nZVI, bare nZVI

78 1, crystalline cellulose, and xylan, but not carboxymethyl cellulose (CMC).

79 h either microfibrillated cellulose (MFC) or carboxymethyl cellulose (CMC).

80 ic-polycytidylic acid with poly-L-lysine and carboxymethyl cellulose (Hiltonol), a potent TLR3 agonis

81 lowing the injection of nZVI stabilized with carboxymethyl cellulose (nZVI-CMC).

82 ice were p.o. fed with vehicle control (0.5% carboxymethyl cellulose and 0.025% Tween 20 in distilled

83 EngO was highly active toward carboxymethyl cellulose but showed no activity towards x

84 te well with analysis of the same samples by carboxymethyl cellulose chromatography.

85 2, ethanol and (NH4)2SO4 precipitations, and carboxymethyl cellulose complexation.

86 Therefore, MP 1:9 incorporated with blended carboxymethyl cellulose film increased the water barrier

87 cid, fulvic acid, alginate, citric acid, and carboxymethyl cellulose greatly enhanced the stability a

88 lanted with HT29 cells and fed with vehicle (carboxymethyl cellulose or phosphatidylcholine) or 200 m

89 The Dex-NW was fabricated using carboxymethyl cellulose polymer and contains arrays of 5

90 (BMCC), filter paper, swollen cellulose, and carboxymethyl cellulose were measured.

91 te, 5 wt % of acetylene black, and 3 wt % of carboxymethyl cellulose with an areal loading higher tha

92 dy shows that the mucoadhesive properties of carboxymethyl cellulose, a commonly used polysaccharide

93 low catalytic activity on swollen cellulose, carboxymethyl cellulose, bacterial microcrystalline cell

94 n appropriate electrode formulation based on carboxymethyl cellulose, carbon black, and vapor ground

95 es which contain only beta-1,4 bonds such as carboxymethyl cellulose, microcrystalline cellulose, Wha

96 ound that inclusion of a viscosity enhancer, carboxymethyl cellulose, overcame this effect and retain

97 natural and nontoxic organic macromolecules (carboxymethyl cellulose, rhamnolipid biosurfactants, and

98 nt enhanced transport of Pd-NZVI coated with carboxymethyl cellulose, rhamnolipid biosurfactants, and

99 h Man5B in the hydrolysis of beta-mannan and carboxymethyl cellulose.

100 y active toward xylan, but not active toward carboxymethyl cellulose.

101 nding affinity for crystalline cellulose and carboxymethyl cellulose.

102 t does not bind to xylan, galactomannan, and carboxymethyl cellulose.

103 nzymes were assayed for their activities on (carboxymethyl)cellulose, phosphoric acid-swollen cellulo

104 ,4-glucans in in vitro cellulase assays with carboxymethyl-cellulose as substrate.

105 Oxygen encapsulated nanosize carboxymethyl cellulosic nanobubbles were developed for

106 he dissociation constants of complexes with (carboxymethyl)chitin complexes, suggesting that ground s

107 D52A ChEWL- and GoEWL-catalyzed cleavage of (carboxymethyl)chitin may be partially fulfilled by an ap

108 y, complex nanoparticles were developed from carboxymethyl chitosan (CMCS) and soy protein isolate (S

109 In this study, zein and zein/carboxymethyl chitosan (CMCS) nanoparticles were prepare

110 ent cation salts CaCl(2), MnCl(2) as well as carboxymethyl chitosan (CMCS) on inhibition of acylation

111 NP) containing a poly(N-isopropylacrylamide)-carboxymethyl chitosan shell and poly lactic-co-glycolic

112 er and magnetite nanoparticles are joined by carboxymethyl chitosan, useful in biological environment

113 oxygen from O2 to form alpha-hydroxy- delta-carboxymethyl cis-muconic semialdehyde.

114 Of the incorporated carboxymethyl (CM) group, 1.1 per subunit, >90% was in C

115 yst-free synthesis of 6-hydroxy indoles from carboxymethyl cyclohexadienones and primary amines has b

116 The cyclohexane derivative cis-2-(carboxymethyl)cyclohexane-1-carboxylic acid [(1R,2R)-/(1

117 exane-1-carboxylic acid [(1R,2R)-/(1S,2S)-2-(carboxymethyl)cyclohexane-1-carboxylic acid] has previou

118 ntaining a longer peptide part modified with carboxymethyl-cytosine instead of adenosine was describe

119 Esters of 5-O-acetyl- or 5-azido-5-deoxy-3-(carboxymethyl)-D-ribofuranose were coupled with nucleoba

120 -deoxyguanosine (M(1)dG) adduct and the O(6)-carboxymethyl-deoxyguanosine (O(6)CMdG) adduct to demons

121 Occurrence of the Se-carboxymethyl derivative of radioactive selenocysteine i

122 ree thiols with iodoacetic acid, forming the carboxymethyl derivative of the cysteine residues, is pr

123 A carboxymethyl derivative of yeast beta-glucan enhanced t

124 (I)-O-, 3(I)-O-, and 6(I)-O-formylmethyl or -carboxymethyl derivatives.

125 In order to immobilize BSA, carboxymethyl dextran hydrogel (CMD) Au chip was used.

126 methods described in this paper) and in the carboxymethyl dextran matrix of commercially available s

127 gG as the detecting molecule, coupled onto a carboxymethyl dextran-coated gold crystal.

128 ific interactions of the HMG proteins with a carboxymethyl-dextran matrix, a novel method using a cho

129 oride) with either adenosine triphosphate or carboxymethyl-dextran using a microfluidic flow-focusing

130 chain onto the reducing end of CMD, forming carboxymethyl-dextran-block-poly(ethylene glycol) (CMD-b

131 A novel radioactive thiol reagent, 1-S-[3H]carboxymethyl-dithiothreitol (DTT-S-C[3H(2)]CO(2)H, [3H]

132 .e., primary amines) or electrophilic (i.e., carboxymethyl esters) functional groups have been covale

133 arboxyl, the first derivative (5) contains a carboxymethyl ether at the 6-position and a secondary am

134 The use of a masked carboxymethyl function off the lactam nitrogen provided

135 2,4,6-trimethylphenyl)-amino]-2-oxoethyl]-N-(carboxymethyl )-glycine ((99m)Tc-mebrofenin) and its ana

136 -one (CP-93,129), sumatriptan, serotonin-5-O-carboxymethyl-glycyl -tyrosinamide (GTI), 5-methylaminos

137 eir modification with the negatively charged carboxymethyl group in monomeric Abeta also destabilized

138 modification with a farnesyl isoprenoid and carboxymethyl group is required for full biological acti

139 modification with a farnesyl isoprenoid and carboxymethyl group is required for full biological acti

140 enzyme activity that demethylates the C13(2)-carboxymethyl group present at the isocyclic ring of Chl

141 arget aspartyl-tRNA synthetase, and that the carboxymethyl group prevents resistance that can occur d

142 mass spectrometry, these FCCs had an intact carboxymethyl group, which slowed down their isomerizati

143 carboxy-SAM, which serves as a donor of the carboxymethyl group.

144 methylene groups from the macrocycle and the carboxymethyl groups occupy the rear and sides of the mo

145 n, N-(p-cyanophenyl)-N'-(diphenylmethyl)-N"-(carboxymethyl)guan idine (NC174), has been determined to

146 The hydrogel was made of amphipathic carboxymethyl-hexanoyl chitosan (CHC), beta-glycerol pho

147 showed that inhibition of CBS activity by O-(Carboxymethyl) hydroxylamine hemihydrochloride (AOAA) si

148 oxy]octanoyl]-sn-glycero-3-N-[11- [N',N'-bis[carboxymethyl]imino]-3,6,9-trioxaundecanoyl] phosphatidy

149 The substrate analog N(2)-(carboxymethyl)-l-arginine (CMA) was adenylated by ATP in

150 ding, the truncated substrate analogue N(2)-(carboxymethyl)-L-arginine was synthesized and demonstrat

151 Target compound 5, the N tau-(carboxymethyl)-L-histidine derivative of 4, was also pre

152 inobutryic acid (GABA) and Nalpha,Nalpha-bis(carboxymethyl)-L-lysine (BCML) as competitive inhibitors

153 determination of free and total Nepsilon-(1-Carboxymethyl)-L-Lysine (CML) and free Nepsilon-(1-Carbo

154 ormation of Amadori products (AP), Nepsilon-(Carboxymethyl)-L-lysine (CML), Nepsilon-(Carboxyethyl)-L

155 using pyrenebutyric acid Nalpha',Nalpha-bis(carboxymethyl)-L-lysine amide (NTA-pyrene) and [tris-(2,

156 IL-COOH was further modified with N,N'-bis (carboxymethyl)-l-lysine hydrate to bind copper ions and

157 f the Maillard reaction (furosine, Nepsilon-(carboxymethyl)-l-lysine, Nepsilon-(carboxyethyl)-l-lysin

158 ion domain of the A/PCP fragment activated S-carboxymethyl-L-cysteine (kcat/Km = 840 mM-1 min-1) at 1

159 One of these compounds, S-carboxymethyl-l-cysteine (SCMC), is currently used for t

160 covalently aminoacylated itself with [35S]S-carboxymethyl-L-cysteine.

161 lation product in the human lens, N(epsilon)-carboxymethyl-L-lysine (CML), has an EDTA-like structure

162 jor advanced glycation end product, Nepsilon-carboxymethyl-L-lysine, ruling out effects of cellular a

163 sphorylation with a nonnatural amino acid, p-carboxymethyl-l-phenylalanine (pCMF), we demonstrated th

164 hemically stable phosphotyrosine analogue (p-Carboxymethyl-L-phenylalanine, pCMF).

165 The higher aromatics are found to yield carboxymethyl lactones derived from the initially formed

166 elle-forming material, folic acid-conjugated carboxymethyl lauryl chitosan (FA-CLC), and superparamag

167 We hypothesized that carboxymethyl lipids such as (carboxymethyl)phosphatidyl

168 resentative glycation structures: N(epsilon)-carboxymethyl lysine (CM-OVA), N(epsilon)-carboxyethyl l

169 on end products (AGEs), including N(epsilon)-carboxymethyl lysine (CML), which have been implicated i

170 r weight, pentosidine content, and N-epsilon-carboxymethyl lysine content.

171 Carboxyethyl lysine, carboxymethyl lysine, and methylglyoxal hydroimidazolone

172 Carboxymethyl lysine, another oxidative modification, wa

173 fasting plasma glucose (FPG), serum N(euro)-(carboxymethyl) lysine (CML), and periodontal parameters

174 ed glycation end product in skin, N-epsilon-(carboxymethyl) lysine (CML)-collagen, could induce fibro

175 n had QW, as detected by an anti-N(epsilon)-(carboxymethyl)lysine (anti-CML) antibody.

176 h as diabetes and renal failure, N(epsilon)-(carboxymethyl)lysine (CML) adducts, are ligands of RAGE.

177 N()-(carboxymethyl)lysine (CML) AGE is one of the major biolo

178 ith regards to the inhibition of N(epsilon)-(carboxymethyl)lysine (CML) formation.

179 the main precursors of AGEs and N(epsilon)-(carboxymethyl)lysine (CML) found to be predominantly hig

180 Of all AGEs, Nepsilon-(carboxymethyl)lysine (CML) is a major glycoxidation prod

181 Nepsilon-(Carboxymethyl)lysine (CML) is a stable chemical modifica

182 Nepsilon-(Carboxymethyl)lysine (CML) is an advanced glycation end

183 on, reacts with proteins to form N(epsilon)-(carboxymethyl)lysine (CML), a chemically well-characteri

184 Furthermore, Nepsilon-(carboxymethyl)lysine (CML), a chemically well-characteri

185 uman serum albumin modified with N(epsilon)-(carboxymethyl)lysine (CML), a major AGE adduct that prog

186 t these effects were mediated by N(epsilon)-(carboxymethyl)lysine (CML), an important AGE found in vi

187 N(epsilon)-(carboxymethyl)lysine (CML), N(epsilon)-(1-carboxyethyl)l

188 Dietary, plasma and urinary AGEs N(euro)-(carboxymethyl)lysine (CML), N(euro)-(carboxyethyl)lysin

189 r the presence of the major AGEs N(epsilon)-(carboxymethyl)lysine (CML), VCAM-1, neutrophilic granulo

190 of a known RAGE protein ligand, N(epsilon)-(carboxymethyl)lysine (CML)-mouse serum albumin (MSA), on

191 of the immunoreactive AGE/ALE N( epsilon )-(carboxymethyl)lysine (CML).

192 Ga(III) or Fe(III) and N(alpha),N(alpha)-bis(carboxymethyl)lysine (LysNTA) in solution and electrospr

193 emistry and Western analysis for N(epsilon)-(carboxymethyl)lysine [CML]) was assessed.

194 n and lipoxidation end products, N(epsilon)-(carboxymethyl)lysine and N(epsilon)-(carboxyethyl)lysine

195 Like the N-carboxy-alkyllysines Nepsilon-(carboxymethyl)lysine and Nepsilon-(carboxyethyl)lysine,

196 lfoxide are formed in concert with Nepsilon-(carboxymethyl)lysine and pentosidine during glycoxidatio

197 The glycoxidation products Nepsilon-(carboxymethyl)lysine and pentosidine increase in skin co

198 two most commonly measured AGEs, N(epsilon)-(carboxymethyl)lysine and pentosidine, are glycoxidation

199 ased in diabetes, in contrast to N(epsilon)-(carboxymethyl)lysine and pentosidine.

200 hibited formation of the AGE/ALE N(epsilon)-(carboxymethyl)lysine during reaction of GO and GLA with

201 nidine inhibited glucose-induced N(epsilon)-(carboxymethyl)lysine formation on beta2M.

202 ein cross-linking and formation of Nepsilon-(carboxymethyl)lysine, an AGE product.

203 lipoxidation end products (ALEs) N(epsilon)-(carboxymethyl)lysine, N(epsilon)-(carboxyethyl)lysine, m

204 dy, plasma levels of protein-bound Nepsilon-(carboxymethyl)lysine, Nepsilon-(carboxyethyl)lysine, and

205 and two subclasses of AGE, i.e., N(epsilon)-(carboxymethyl)-lysine (CML) and pentosidine (PENT).

206 agnostic serum concentrations of sRAGE or N-(carboxymethyl)-lysine (CML)-AGE and hepatocellular carci

207 ons of prediagnostic measures of N(epsilon)-(carboxymethyl)-lysine (CML)-AGE and sRAGE with pancreati

208 etical RyR2 peptides with single N(epsilon)-(carboxymethyl)-lysine, imidazolone A, imidazone B, pyrra

209 vels were determined by ELISA for N(epsilon)-carboxymethyl-lysine (CML) and methylglyoxal-derivatives

210 ease of LDH and lower glycoxidation products carboxymethyl-lysine (CML) and pentosidine, improved fun

211 o far been thought to have a high N(epsilon)-carboxymethyl-lysine (CML) content.

212 N(epsilon)-carboxymethyl-lysine (CML) is measured in food, but ther

213 e immunity, while increased serum N(epsilon)-carboxymethyl-lysine (CML), an advanced glycation end pr

214 d skin samples were monitored for N(epsilon)-carboxymethyl-lysine and methylglyoxal derivatives by en

215 Neither carboxymethyl-lysine nor glyoxal hydroimidazolone, two m

216 ard reaction markers (hydroxymethylfurfural, carboxymethyl-lysine, absorbance at 420nm and total fluo

217 mocitrulline accumulates more intensely than carboxymethyl-lysine, one of the major advanced glycatio

218 This derivative, N,N-bis[carboxymethyl]lysine (BCML), was easily coupled to a mal

219 gressive increase in RAGE ligands (S100B, N-[carboxymethyl]lysine, HSP70, and HMGB1).

220 , glycoxidation (pentosidine and N(epsilon)-[carboxymethyl]-lysine [CML]), and crosslinking (acid and

221 ogs, the migrastatin core ether (ME) and the carboxymethyl-ME (CME), which exhibit high efficacy in b

222 vestigated using NO photolyzed from N,N'-bis(carboxymethyl)-N,N'-dinitroso-p-phenylenediamine using a

223 To this end, the N1-carboxymethyl-NAD+ species were covalently attached to p

224 Carboxymethyl-ornithine and furornithine increased with

225 The proteins were assayed for carboxymethyl-ornithine and glycated ornithine ("furorni

226 R agonists E-6-BSA-FITC [beta-estradiol-6-(O-carboxymethyl)oxime-bovine serum albumin conjugated with

227 Various amide derivatives of 8-[4-[[carboxymethyl]oxy]phenyl]-1,3-di-(n-propyl)xanthine, 4a,

228 usly shown to recognize CML, suggesting that carboxymethyl-PE may be a component of AGE lipids detect

229 as (carboxymethyl)phosphatidylethanolamine (carboxymethyl-PE) would also be formed in these reaction

230 and NODA-MPAA is 2-[4-(carboxymethyl)-7-{[4-(carboxymethyl)phenyl]methyl}-1,4,7-triazacyclononan-1 -y

231 n inhibitor containing the singly charged p-(carboxymethyl)phenylalanine residue (cmF) as a phosphoty

232 information presented here suggests that the carboxymethyl-phenylalanine residue may be a viable Tyr(

233 othesized that carboxymethyl lipids such as (carboxymethyl)phosphatidylethanolamine (carboxymethyl-PE

234 la-Val-Gly-His-Sta-Leu-NH(2) (Pip, 4-amino-1-carboxymethyl-piperidine), was conjugated to 1,4,7-triaz

235 ]-BN(6-14)NH2 (DOTA-AR), and DOTA-(4-amino-1-carboxymethyl-piperidine)-[D-Phe(6), Sta(13)]-BN(6-14)NH

236 (68)Ga-labeled DOTA-4-amino-1-carboxymethyl-piperidine-d-Phe-Gln-Trp-Ala-Val-Gly-His-S

237 (68)Ga-labeled DOTA-4-amino-1-carboxymethyl-piperidine-D-Phe-Gln-Trp-Ala-Val-Gly-His-S

238 irst substrate to bind followed by (2S,5S)-5-carboxymethyl proline and PPi is the last product releas

239 -carbapenam-3-carboxylic acid from (2S,5S)-5-carboxymethyl proline based on characterization of the p

240 proposed a role for each moiety of (2S,5S)-5-carboxymethyl proline for binding to the active site of

241 -carbapenam-3-carboxylic acid from (2S,5S)-5-carboxymethyl proline.

242 The substituted-5-carboxymethyl-prolines were converted into the correspon

243 ursors in syntheses of the neuroexcitants 3-(carboxymethyl)pyrrolidine-2,4-dicarboxylic acid 43, alph

244 Cross-linked carboxymethyl rice starches (CL-CMRSs) were prepared fro

245 the novel tyrosine phosphate bioisostere, O-carboxymethyl salicylic acid; demonstration that the tyr

246 y Edman degradation identified residue 16 as carboxymethyl selenocysteine, which corresponded to the

247 iodoacetate or 3-bromopropionate yielded Se-carboxymethyl-selenocysteine or Se-carboxyethyl-selenocy

248 te matter by a series of chromatographies on carboxymethyl-Sephadex and silica gel in chloroform and

249 tion of N-(glucitol)ethanolamine (GE) and N-(carboxymethyl)serine (CMS), two products of nonenzymatic

250 1-O-Alkyl-2-carboxymethyl-sn-glycero-3-phosphocholine (Edelfosine) l

251 For the subsequent migration of the carboxymethyl substituent, two possible directions were

252 The degree of carboxymethyl substitution was between 0.24 and 0.28, wh

253 nosine-L-methionine (Cx-SAM) and catalyzes a carboxymethyl transfer reaction resulting in formation o

254 decylphosphonium bromide (1P14CONH(2)Br) and carboxymethyl-tri-n-tetradecylphosphonium bromide (1P14C

255 amine, generated through the condensation of carboxymethyl unit of the substrates with an external am