ライフサイエンスコーパス: cardiac mesoderm

1 n factor cascade to direct the generation of cardiac mesoderm.

2 subset of ME genes that is required to form cardiac mesoderm.

3 s), GATA4 was shown to promote endoderm, not cardiac mesoderm.

4 ing during mesoderm specification and in pre-cardiac mesoderm.

5 ch signaling during the prepatterning of the cardiac mesoderm.

6 spatial specificity of eve expression in the cardiac mesoderm.

7 hereas the Lbe cells are expanded within the cardiac mesoderm.

8 recisely targeted gene expression within the cardiac mesoderm.

9 xpression that specify cell types within the cardiac mesoderm.

10 d work in parallel to FGF signaling from the cardiac mesoderm.

11 sors and in tissues involved in induction of cardiac mesoderm.

12 of a combinatorial mechanism to specify the cardiac mesoderm.

13 a molecular pathway regulating the posterior cardiac mesoderm and demonstrate that cardiovascular def

14 nhibition did not generate lateral plate and cardiac mesoderm and favored instead somitic differentia

15 P-TFI and II), is initially activated in the cardiac mesoderm and is subsequently restricted to cells

16 of the yolk sac; the distal region generates cardiac mesoderm and node-derived axial mesendoderm; and

17 the AIP can induce cardiac identity from non-cardiac mesoderm and that it can pattern this by specify

18 evelopment to promote the development of the cardiac mesoderm and thus all heart cells.

19 4 stages: pluripotent stem cells, mesoderm, cardiac mesoderm, and differentiated cardiomyocytes.

20 tration threshold of FGFs emanating from the cardiac mesoderm are involved in patterning the foregut

21 GF2, but not FGF8, was sufficient to replace cardiac mesoderm as an inducer of the liver gene express

22 GATA-6 is expressed in presumptive cardiac mesoderm before gastrulation, but its role in he

23 ory framework for the differentiation of the cardiac mesoderm, beginning at the 110-cell stage, and e

24 primarily by regulating cell fate within the cardiac mesoderm between muscular and non-muscular cell

25 erminants influence the specification of the cardiac mesoderm, both by inhibiting inductive signals r

26 l, mutually redundant role in specifying the cardiac mesoderm (CM) as eliminating the functions of bo

27 ranscription factors involved in somitic and cardiac mesoderm development in diverse bilaterians.

28 as a classical Polycomb protein during early cardiac mesoderm differentiation by repressing pluripote

29 srupted myosin heavy chain expression during cardiac mesoderm differentiation.

30 FGF signalling from the cardiac mesoderm diverts this endoderm to express genes

31 haracterized by absence of prechordal plate, cardiac mesoderm, endoderm and ventral neuroectoderm.

32 we uncover complex interactions between the cardiac mesoderm, endoderm, and the rest of the embryo,

33 man homeodomain gene needed for visceral and cardiac mesoderm formation in Drosophila.

34 s is both necessary and sufficient to direct cardiac mesoderm formation in frog embryos and human emb

35 elopmental pathway in which pannier promotes cardiac mesoderm formation, and pointed acts subsequentl

36 thereby blocking a direct route to embryonic cardiac mesoderm formation.

37 to the interface between the pharyngeal and cardiac mesoderm, identify the transcription factor code

38 essed in endoderm underlying the presumptive cardiac mesoderm in amphibian, bird, and mammalian embry

39 ion factor required for specification of the cardiac mesoderm in Ciona embryos.

40 Tbx6-Mesp interactions for the evolution of cardiac mesoderm in invertebrates and vertebrates.

41 endoderm as essential for differentiation of cardiac mesoderm in response to Nodal.

42 required for formation of both visceral and cardiac mesoderm, including formation of the dorsal vess

43 ordination between the endoderm and adjacent cardiac mesoderm is crucial for heart development.

44 The cardiac mesoderm is therefore not passively patterned by

45 that Rho kinase transcripts were enriched in cardiac mesoderm, lateral plate mesoderm and the neural

46 blasts into replicative cells expressing the cardiac mesoderm marker KDR(+).

47 xposure of YAP(-/-) hESCs to Activin induces cardiac mesoderm markers (BAF60c and HAND1) without acti

48 captured EYFP+ cells that strongly expressed cardiac mesoderm markers and cardiac transcription facto

49 nscription factor 1 (MESP1; from mesoderm to cardiac mesoderm), meis homeobox 1 (MEIS1) and GATA-bind

50 The bilateral cardiac mesoderm migrates from the lateral region of the

51 nderlying early stages (ie, from mesoderm to cardiac mesoderm) of cardiomyocyte differentiation remai

52 rt defects (CHDs) are the result of abnormal cardiac mesoderm or cardiac neural crest development.

53 Cardiac mesoderm or FGF induces the local expression of

54 therefore conclude that proper maturation of cardiac mesoderm requires GATA-6, which functions to mai

55 The iCPCs were cardiac mesoderm-restricted progenitors that could be ex

56 Differentiation of extra-embryonic and cardiac mesoderm seems to be unaffected.

57 Cardiac mesoderm-specific loss-of-function of YY1 result

58 enhanced neural differentiation and limited cardiac mesoderm specification.

59 of pannier further aggravates the deficit in cardiac mesoderm specification.

60 kx2-5 is among the earliest known markers of cardiac mesoderm that is central to the regulatory pathw

61 but how the pathway switches from promoting cardiac mesoderm to restricting cardiomyocyte progenitor

62 d acts downstream of GATA factors in the pre-cardiac mesoderm to specify lineage commitment of cardio

63 In the absence of cardiac mesoderm, ventral foregut endoderm explants resp

64 des positional information to the underlying cardiac mesoderm via inductive signals.

65 the precise pattern of eve expression in the cardiac mesoderm via this enhancer.

66 The GATA-6 requirement in cardiac mesoderm was confirmed in zebrafish, an organism

67 Importantly, in pre-cardiac mesoderm we define a new mechanism where Wnt sig

68 during mesoderm specification and in the pre-cardiac mesoderm, we find a previously unrecognized role

69 rmal cells maintain contact with nascent pre-cardiac mesoderm, we hypothesized that direct physical c

70 at co-expression of these three genes in the cardiac mesoderm, which also involves cross-regulation,

71 y broad regions of mesoderm, including early cardiac mesoderm, which are derived from Tbx1-expressing

72 Close proximity of cardiac mesoderm, which expresses fibroblast growth fact

73 to hepatic specification, direct contact of cardiac mesoderm with ventral endoderm is required to in