ライフサイエンスコーパス: cardiac valve

1 rt development necessary to the formation of cardiac valves.

2 tribution were found both between and within cardiac valves.

3 ralization of the arterial blood vessels and cardiac valves.

4 potentially therapeutic regeneration of the cardiac valves.

5 cal event for the embryonic morphogenesis of cardiac valves.

6 ibomian glands, and defects in the semilunar cardiac valves.

7 Cs are a constituent of the normal aorta and cardiac valves.

8 perties, and pathobiological behavior of the cardiac valves.

9 M), predominates in the supporting tissue of cardiac valves.

10 pproaches to therapeutic regeneration of the cardiac valves.

11 ncluding the intima and media of vessels and cardiac valves.

12 tissue remodeling formed the leaflets of the cardiac valves.

13 gies to guide tissue formation in engineered cardiac valves.

14 ocardial Nfatc1 expression within developing cardiac valves.

15 scription factor required for development of cardiac valves.

16 and for its adhesion to the vessel wall and cardiac valves.

17 perspectives on transcatheter replacement of cardiac valves.

18 of pathological microfractures in calcified cardiac valves.

19 Although patients with certain cardiac valve abnormalities have increased risk of infec

20 ents (53 of 233) met the case definition for cardiac-valve abnormalities (odds ratio, 22.6; 95 percen

21 There were no cases of idiopathic cardiac-valve abnormalities among the subjects who had n

22 After case reports of cardiac-valve abnormalities related to the use of appeti

23 The odds ratio for such cardiac-valve abnormalities was 12.7 (95 percent confide

24 ween the use of any appetite suppressant and cardiac-valve abnormalities was analyzed in a final matc

25 The presence of cardiac-valve abnormalities, defined by the Food and Dru

26 was used to identify factors associated with cardiac-valve abnormalities.

27 of papillary muscles, the fibrous tissue of cardiac valve and chordae tendineae and the course of co

28 correlated with severity of disease, causing cardiac valve and septal disease in the neonate that was

29 Cs proved to be particularly abundant in the cardiac valves and aortic sinus.

30 r arrhythmias, and percutaneous placement of cardiac valves and closure devices will also be discusse

31 realistic and unique comprehensive views of cardiac valves and congenital abnormalities.

32 cells and is necessary for formation of the cardiac valves and for complete cardiac septation.

33 docardial cushions are the precursors of the cardiac valves and form by a process of epithelial-mesen

34 riable morphology, were detected in all four cardiac valves and in some tendinous cords.

35 Hyperplasia of the cardiac valves and outflow tract septation defects indic

36 Abnormal development of the cardiac valves and septae is the most frequent form of b

37 formation exists on the innervation of human cardiac valves and the relationship of nerve fibers and

38 ed endocardium and fail to form identifiable cardiac valves and trabeculae.

39 s prevalent, such as in the formation of the cardiac valves and trabeculae.

40 c surgery, including coronary artery bypass, cardiac valve, and aortic procedures, is among the most

41 Cardiac valves are essential to direct forward blood flo

42 Cardiac valves arise from endocardial cushions, speciali

43 h mineralization can occur at various sites (cardiac valves, arterial intima or media, capillaries),

44 c OPN and Msx2 expression >50% and decreased cardiac valve calcification 80% (8.3 +/- 1.5% versus 1.4

45 Furthermore, adult mutant mice exhibit cardiac valve calcifications associated with abnormal ma

46 on of the pathomorphological features of the cardiac valves compared with previously used sparse arra

47 development of the embryonic outflow tract, cardiac valves, conducting system, and the developing co

48 -/-) embryos as well as additional semilunar cardiac valve defects and a double-outlet right ventricl

49 Cardiac valve defects are a common congenital heart malf

50 ogical approaches show that NS mutants cause cardiac valve defects by increasing Erk MAPK activation,

51 hisms in a patient population suffering from cardiac valve defects.

52 Defining molecular factors in cardiac valve development has facilitated identification

53 ulates the release of active TGF-beta during cardiac valve development in the avian heart.

54 to better understand its mechanistic role in cardiac valve development.

55 ry pathways that control normal and abnormal cardiac valve development.

56 sly to play important and selective roles in cardiac valve development.

57 Patients with cardiac valve disease (CVD) frequently have congestive h

58 The pathogenesis of cardiac valve disease correlates with the emergence of m

59 f TNF and inflammation in the development of cardiac valve disease in man.

60 Mitral valve prolapse (MVP) is a common cardiac valve disease that affects nearly 1 in 40 indivi

61 cytopenia, 1, 1, 2, and 0, respectively; for cardiac valve disease, 0, 0, 3, and not analyzed, respec

62 r C. burnetii in antiphospholipid-associated cardiac valve disease, and performing early echocardiogr

63 In some persons, particularly those with cardiac valve disease, infection with C. burnetii can ca

64 aPL-positive patients with thrombocytopenia, cardiac valve disease, skin ulcer, aPL nephropathy, and/

65 etiology of both degenerative and rheumatic cardiac valve diseases.

66 five-year cumulative incidence of idiopathic cardiac-valve disorders was 0 per 10,000 subjects among

67 ed with an increased risk of newly diagnosed cardiac-valve disorders, particularly aortic regurgitati

68 in abundantly expressed in great vessels and cardiac valves during embryogenesis, and in many adult t

69 f cell phenotypes and matrix architecture in cardiac valves during fetal maturation and postnatal ada

70 microRNA 21 (miR-21), which is expressed in cardiac valve endothelium during development, in order t

71 E416D mutant enzymes were unable to restore cardiac valve formation and could only partially rescue

72 hese results suggest that FOG-2 functions in cardiac valve formation as an attenuator of EMT by repre

73 h signaling pathway is crucial for primitive cardiac valve formation by epithelial-mesenchymal transi

74 Cardiac valve formation is a complex process that involv

75 During cardiac valve formation, Dll4-Notch1 signaling leads to

76 e gene expression in lymphocytes and control cardiac valve formation.

77 l-transduction processes required for normal cardiac valve formation.

78 Several gene mutations are known to affect cardiac valve formation.

79 Human cardiac valves have distinct patterns of innervation tha

80 comitant inflammation of synovial joints and cardiac valves in disorders such as rheumatic fever and

81 is specifically prevented the development of cardiac valve inflammation.

82 clinical sequelae, such as life-threatening cardiac valve involvement.

83 and that renal stones developed at 64 years, cardiac-valve involvement at 54 years, and coronary-arte

84 lopment of the extracellular matrix (ECM) of cardiac valves is necessary for proper heart function.

85 r, these results suggest a role of FGF-4 for cardiac valve leaflet formation through proliferative ex

86 Cardiac valve leaflets and large conduit arteries have b

87 Cardiac valve leaflets develop from rudimentary structur

88 diovascular development in the maturation of cardiac valve leaflets.

89 activation may be an important mechanism in cardiac valve maintenance and function by enhancing endo

90 tor to transduce reverse signals involved in cardiac valve maturation and axon pathfinding.

91 predominantly by valvular endocardium during cardiac valve maturation, exhibited enlarged valves.

92 Defects in cardiac valve morphogenesis and septation of the heart c

93 ial-mesenchymal transformation (EnMT) during cardiac valve morphogenesis.

94 PFE occurred most commonly on cardiac valves (n = 400 [78%]).

95 Cardiac valves of transgenic mice expressing human TNF d

96 ic surgery, it now is apparent that standard cardiac valve operations can be performed through very s

97 acement, or a previous operation involving a cardiac valve or ascending aorta.

98 rdiogenic emboli in patients with mechanical cardiac valves or nonvalvular atrial fibrillation.

99 es in either initial adherence of strains to cardiac valves or vegetation weights.

100 Cardiac valves originate from endocardial cushions (EC)

101 ighly expressed in the embryonic periosteum, cardiac valves, placenta, and periodontal ligament as we

102 Cardiac valve procedures are commonly performed concurre

103 an and GAS proteins triggers proinflammatory cardiac valve-reactive T cells.

104 mine is associated with an increased risk of cardiac-valve regurgitation.

105 e impacted by the findings of these studies: cardiac valve repair and replacement, assessment of vent

106 aving coronary artery bypass grafting and/or cardiac valve repair or replacement from 2009 to 2011.

107 of US kidney transplantation patients after cardiac valve replacement and to compare associations of

108 Although some patients who require cardiac valve replacement clearly benefit more from one

109 Allograft valves have been used in cardiac valve replacement for 35 years.

110 142 women; mean age 68 years) who underwent cardiac valve replacement surgery between 1994 and 1998.

111 portion pulmonary hypertension who underwent cardiac valve replacement surgery.

112 rence in survival of dialysis patients after cardiac valve replacement with tissue versus nontissue p

113 hip fracture repair, lung cancer resection, cardiac valve replacement, coronary angioplasty, pancrea

114 scheduled for coronary artery bypass graft, cardiac valve replacement, or both.

115 on patients hospitalized in 1991 to 2004 for cardiac valve replacement.

116 r findings, including abnormalities of other cardiac valves, septal defects, persistent left superior

117 nd short-axis imaging readily disclosed each cardiac valve, support structures and chamber, as well a

118 nomorphic ventricular tachycardia (VT) after cardiac valve surgeries have not been studied extensivel

119 Cardiac valve surgery has seen a rapid and ongoing evolu

120 Cardiac valve surgery is, consequently, becoming much mo

121 ing, percutaneous coronary intervention, and cardiac valve surgery were most strongly associated with

122 Among patients referred for cardiac valve surgery, age does not appear to limit the

123 ans for percutaneous coronary interventions, cardiac valve surgery, and pediatric cardiac surgery (on

124 oaches have become increasingly important in cardiac valve surgery.

125 ong-term survival of dialysis patients after cardiac valve surgery.

126 e review the evolution of minimally invasive cardiac valve surgery.

127 laces both native cardiac ventricles and all cardiac valves, thus eliminating problems commonly seen

128 es, we developed a tissue model using rabbit cardiac valves to investigate the interaction of A. acti

129 acterial adhesion to the vessel wall and the cardiac valves under flow.

130 in zebrafish embryos leads to hypercellular cardiac valves, whereas Notch inhibition prevents valve

131 opmental valve anomalies and have myxomatous cardiac valves with 100% penetrance.