ライフサイエンスコーパス: carriage

1 higher rates among those with nasopharyngeal carriage.

2 en HIV infection status and rectovaginal GBS carriage.

3 were associated with increased meningococcal carriage.

4 Primaquine substantially reduced gametocyte carriage.

5 od culture contaminants and from nonhospital carriage.

6 did not affect serotype-specific immunity or carriage.

7 olunteers with previous natural pneumococcal carriage.

8 iage, 15% remained carriers, and 7% acquired carriage.

9 sing bacterial populations without affecting carriage.

10 , while 23vPPV had no effect on vaccine-type carriage.

11 adders of humans and mouse models of chronic carriage.

12 eptides in a murine model of S. aureus nasal carriage.

13 associated with asymptomatic nasopharyngeal carriage.

14 d IL-17F in the clearance of S. aureus nasal carriage.

15 e macrophage phenotypes according to E. coli carriage.

16 L4, DEFB1, CRP, and VDR for persistent nasal carriage.

17 ion of Streptococcus pneumoniae in pediatric carriage.

18 ve a high risk of progressing to chronic HBV carriage.

19 hanisms underlying these conserved stages of carriage.

20 cytokine mRNA profiles according to E. coli carriage.

21 l impact of PCV13 over PCV7 on reducing ANSP carriage.

22 cute pharyngitis and subsequent asymptomatic carriage.

23 d the dominant serotype in multiple serotype carriage.

24 r densities than ST618 during nasopharyngeal carriage.

25 with protection against sepsis but not nasal carriage.

26 RPEC) infection, and risk factors for MCRPEC carriage.

27 oncentration, adverse events, and gametocyte carriage.

28 vestigated MenB-FHbp impact on meningococcal carriage.

29 rify the relation between HIV-status and GBS carriage.

30 transmitted via asymptomatic nasopharyngeal carriage.

31 urveys: 71% remained noncarriers, 8% cleared carriage, 15% remained carriers, and 7% acquired carriag

32 d test approaches for detecting asymptomatic carriage, (2) compare prophylactic efficacy across antim

33 ed GBS; among 68 babies born to mothers with carriage, 26 (38% [95% CI, 27 to 51%]) had GBS on their

34 Ten students acquired serogroup B carriage: 3 after 1 MenB-FHbp dose, 4 after 2 doses, and

35 ost traits considered here (age and previous carriage) accounted for less than 5%.

36 sure, are associated with protection against carriage acquisition.

37 eningococcal carriage or prevent serogroup B carriage acquisition.

38 eeping operations: screening for V. cholerae carriage, administering prophylactic antimicrobial chemo

39 immunogenicity and effect on nasopharyngeal carriage after 0, 1, 2, or 3 doses of 7-valent pneumococ

40 event changes in H. influenzae and S. aureus carriage among PCV7 recipients.

41 (ESBL)-producing Enterobacteriaceae and CRE carriage among solid organ transplant recipients to info

42 terologous challenge with 6B resulted in 50% carriage among volunteers with previous natural pneumoco

43 Here 211 meningococcal carriage and >1,400 disease isolates were surveyed for t

44 ed the relationships between CDKN2A mutation carriage and 2-mm, 5-mm, and atypical nevus counts among

45 L-17A significantly influences streptococcal carriage and alters local inflammatory responses in two

46 have a large, rapid impact on meningococcal carriage and are unlikely to provide herd protection in

47 were no associations between protection from carriage and baseline levels of 6BPS IgG in serum or nas

48 illin-resistant Staphylococcus aureus (MRSA) carriage and bloodstream infection (BSI), which shows a

49 sk of infection, the reasons for higher MRSA carriage and BSI rates in males, the value of gender-spe

50 infections, resulting in increased bacterial carriage and complications such acute otitis media, pneu

51 Here, we analyzed Staphylococcus aureus carriage and CPIs recorded simultaneously in a long-term

52 The joint analysis of carriage and CPIs showed that CPI paths linking incident

53 ons can largely be prevented by detection of carriage and decolonization treatment upon admission.

54 Independent of carriage and DEFB promotor haplotype, a 1-unit increase

55 There was no relationship between GBS carriage and demographic characteristics, alpha-diversit

56 the effects of viral infection on bacterial carriage and density of Streptococcus pneumoniae, Moraxe

57 Bacterial carriage and density were determined using quantitative

58 We used data on pneumococcal carriage and disease from Navajo Nation children and adu

59 High-resolution genetic analyses of carriage and disease isolates can establish epidemiologi

60 Genome content is highly conserved between carriage and disease isolates, and differential gene exp

61 emporal stability and temporally overlapping carriage and disease populations for MenY clones but als

62 cines MenB-FHbp and MenB-4C on meningococcal carriage and herd protection.

63 llele homozygosity and rs174448 major allele carriage and improved performance in 8- to 11-y-old boys

64 inked to disease severity such as gametocyte carriage and infection chronicity is less well understoo

65 < .001), and genome data indicated matching carriage and infection isolates in 80% of isolate pairs.

66 n framework, we found that serotype-specific carriage and invasiveness (disease incidence divided by

67 The pre-PCV7 proportion of VT carriage and IPD are the main determinants for the impac

68 and to explore a potential link between MRSA carriage and markers of social and material deprivation.

69 We analyzed nasopharyngeal pneumococcal carriage and nasopharyngeal and oropharyngeal NTHi carri

70 ationship between pathogenic CDKN2A mutation carriage and other nevus phenotypes including counts of

71 the transition from disease to asymptomatic carriage and provides new information about this poorly

72 However, the role of S. aureus carriage and SE sensitization on allergic multimorbidity

73 o study associations of both nasal S. aureus carriage and SE sensitization to allergic disease and al

74 Staphylococcus aureus (S. aureus) carriage and sensitization to S. aureus enterotoxins (SE

75 ously shown an association between S. aureus carriage and severe allergic disease and allergic multim

76 ay have an additive benefit of reducing MDRO carriage and should be further investigated as a potenti

77 re common in strains with a long duration of carriage and that mechanisms maintaining diversity in du

78 cal conjugate vaccine (PCV7) on pneumococcal carriage and the bacterial component of the nasopharynge

79 njugate vaccine on serogroup Y meningococcal carriage and to define the dynamics of carriage in high

80 he continuum of care, including asymptomatic carriage and transmission of CRE.

81 iasis, while G1 associates with asymptomatic carriage and undetectable parasitemia.

82 evelopment of drug resistance, modulation of carriage and virulence traits, and evasion of host immun

83 the impact of the vaccine on nasopharyngeal carriage, and population immunity after introduction of

84 after infection, fewer macrophages later in carriage, and prolonged bacterial colonization.

85 insufficient for detecting multiple serotype carriage, and there are few data comparing the new metho

86 actamase-producing Enterobacteriaceae rectal carriage as a way to predict their involvement in ventil

87 ave long focused on eradicating asymptomatic carriage as well as disease, resulting in changes in the

88 conditions.Results:FADS, rs1535 minor allele carriage associated with lower whole-blood arachidonic a

89 nd seasonal distributions, but polymicrobial carriage associations persisted after controlling for th

90 independently associated with ESBL-E rectal carriage at hospital admission (adjusted odds ratio, 3.8

91 ximately 70% of the countywide cases of MRSA carriage averted after 1 year of universal ICU decoloniz

92 apparent transient increase in H. influenzae carriage but no further significant differences in carri

93 or containment and clearance of pneumococcal carriage, but also highlights an important yet often und

94 fectiousness to mosquitoes and P. falciparum carriage by an ultrasensitive RNA-based diagnostics in 1

95 ound to be significantly associated with GBS carriage by linear discriminant analysis.

96 The inhibition of meningococcal carriage by N. lactamica is even more potent than after

97 plicity of infections by nPCR and gametocyte carriage by nucleic acid sequence-based amplification.

98 Carriage by the mother was associated with greater acqui

99 determined the prevalence of nasopharyngeal carriage by undertaking cross-sectional surveys in rando

100 prevalence of MCRPE in human infections and carriage, clinical associations of mcr-1-positive Escher

101 2 PspA sequences derived from a pneumococcal carriage cohort, this OMV-based vaccine formulation cont

102 rst week of life have higher bifidobacterial carriage compared to exclusively breast-fed counterparts

103 te, the strain recovered during asymptomatic carriage contained three single nucleotide polymorphisms

104 ncing tool to screen patients for Klebsiella carriage could inform health care staff of the risk of i

105 fore, the impact of MCV4-DT on meningococcal carriage could not be determined.

106 Independent carriage data from studies conducted on the African and

107 The carriage density in samples extracted from filter paper

108 Because carriage determines transmission, these results suggest

109 Fitness effects of carriage differed between plasmids and were strongly con

110 in promoter-binding assays, and risk allele carriage diminished transcriptional correlations among I

111 uccessfully reduced meningitis incidence and carriage due to Neisseria meningitidis group A (MenA).

112 sequences as being associated with decreased carriage duration independent of serotype, potentially b

113 table to the largest sources of variation in carriage duration: serotype (17%), drug-resistance (9%)

114 ease indirectly by disrupting nasopharyngeal carriage (e.g., herd protection).

115 ed to decide whether screening for long-term carriage (e.g., in health care workers) is warranted.

116 coccus and, after clearance of their natural carriage episode, challenged them with a heterologous 6B

117 veloped a model to calculate the duration of carriage episodes from longitudinal swab data, and combi

118 Despite the frequency of GAS carriage, few investigations into the contributory molec

119 We therefore assessed meningococcal carriage following a MenB vaccination campaign in respon

120 Carriage for Neisseria meningitidis (P < 0.05) and Neiss

121 Klebsiella pneumoniae carriage frequencies were estimated at 6% (95% confidenc

122 nd (i) the rate of maternal rectovaginal GBS carriage, (ii) the rate of vertical transmission of GBS,

123 ge and nasopharyngeal and oropharyngeal NTHi carriage in 13 541 samples collected over 6909 study vis

124 rial efficacy, we set out to survey parasite carriage in 3 communities in North Sumatera Province.

125 ission (p<0.0001) was associated with MCRPEC carriage in 35 patients compared with 378 patients with

126 Given the approximate prevalence of HLA-B*53 carriage in African (20%) and Hispanic (6%) populations,

127 by rapidly ameliorating the cost of plasmid carriage in all environments.

128 a relatively lower/ delayed bifidobacterial carriage in cesarean-born babies.

129 Moreover, carriage in children, invasiveness in children, and a se

130 illin-resistant Staphylococcus aureus (MRSA) carriage in dental clinics.

131 We observed mcr-1 carriage in E coli isolates collected from 78 (15%) of 5

132 occal carriage and to define the dynamics of carriage in high school students.

133 Genome-wide association studies (GWASs) for carriage in humans identified SNPs in IL4, DEFB1, CRP, a

134 At baseline, natural N. meningitidis carriage in the control group was 22.4% (36/161), which

135 s most commonly associated with asymptomatic carriage in the nasopharyngeal cavity, as opposed to the

136 Asymptomatic carriage in the nasopharynx is a prerequisite for diseas

137 a-analysis to obtain the odds of pre-PCV7 VT carriage in the respective settings.

138 ion in acquisition of Gram-negative bacteria carriage in the respiratory tract during the ICU stay.

139 surfaces and promotes both cariogenicity and carriage in vivo.

140 However, bacterial colonization (or carriage) in the upper airway is the prerequisite of all

141 age plays such a role, with long duration of carriage increasing the fitness advantage gained from re

142 indings suggest heterogeneity in duration of carriage is a partial explanation for the coexistence of

143 Understanding pneumococcal carriage is essential for evaluating the impact of pneum

144 Study of meningococcal carriage is essential to understanding the epidemiology

145 e of Streptococcus pneumoniae (pneumococcus) carriage is higher in adults who are infected with human

146 The prevalence of nasopharyngeal carriage is low and the profile of Hib antibodies sugges

147 Approximately 97% lower Salmonella carriage is measured in a treated group, 14 days post-Sa

148 the serotype replacement observed in non-VT carriage is not paralleled in the incidence of OM due to

149 ), was resolved into one subcluster with 86% carriage isolates and a second with 90% invasive isolate

150 te diagnostic approaches to characterize MnB carriage isolates are required.

151 ernight doubled the yield of N. meningitidis carriage isolates compared with conventional methods.

152 isolates, which can be readily serogrouped, carriage isolates often lack capsule expression, making

153 nome sequence data were obtained for 99 MenY carriage isolates recovered in the United Kingdom during

154 In contrast, only 47% of carriage isolates were groupable by genotypic methods, d

155 in the polysaccharide groups associated with carriage isolates.

156 ch for the characterization of meningococcal carriage isolates.

157 sters containing closely related disease and carriage isolates.

158 g and capsular genogrouping of meningococcal carriage isolates.

159 ly nongroupable strains accounted for 88% of carriage isolates.

160 accumulation of within-host diversity during carriage might limit the interpretation of sequencing da

161 We utilized a murine genital tract carriage model to demonstrate that M1 and M28 GAS coloni

162 cterium with an oropharyngeal/nasopharyngeal carriage niche that is associated with a range of opport

163 Detection and decolonization of S. aureus carriage not only prevents S. aureus surgical-site infec

164 S. pneumoniae and find that the duration of carriage of a serotype is indeed positively correlated w

165 nificant added benefit over PCV7 in reducing carriage of ANSP.

166 ted in a paradigm shift from focusing on the carriage of antibiotic resistance in pathogenic bacteria

167 Antibiotic use is the main driver for carriage of antibiotic-resistant bacteria.

168 Carriage of at least one high-expression HLA-DPB1 allele

169 t also gain beneficial capabilities, such as carriage of bacterial food (proto-farming) and defense a

170 Despite the high frequency of asymptomatic carriage of bacterial pathogens, we understand little ab

171 1) were associated with subsequent childhood carriage of ciprofloxacin-resistant E. coli; antibiotic

172 Detection of patients with gastrointestinal carriage of CPO is necessary to interrupt their spread w

173 nscription-qPCR approach, we demonstrate the carriage of eight signature infant-associated Bifidobact

174 that BSH has roles in Fe homeostasis and the carriage of Fe-S clusters to apo-proteins in S. aureus.

175 rs and fishmongers were screened for enteric carriage of GBS.

176 ll as significant reduction of oropharyngeal carriage of group A meningococci in vaccinated and unvac

177 the molecular genetic mechanisms underlying carriage of group A Streptococcus (GAS), we performed wh

178 f immune cells associated with the long-term carriage of HCMV has been linked with poor responses to

179 present study provides strong evidence that carriage of high-expression MIF alleles is a genetic mar

180 Although asymptomatic carriage of human malaria species has been widely report

181 patients were screened for rectal and throat carriage of K. pneumoniae shortly after admission.

182 Carriage of MC1R variants was associated with amelanotic

183 etermine whether phenotypic characteristics, carriage of MC1R variants, and history of amelanotic mel

184 ase-control study to assess risk factors for carriage of MCRPEC in rectal swabs from inpatients with

185 ifferent serotypes exist, and nasopharyngeal carriage of multiple serotypes is common.

186 taining vaccines has the potential to affect carriage of N. cinerea and other commensal species.

187 observation of natural immunity conferred by carriage of N. lactamica.

188 Carriage of N. meningitidis was investigated by using th

189 s expressing protective HLA class I alleles, carriage of Nef codon 9 variants was also associated wit

190 on function in HIV-1 subtype C and show that carriage of Nef variants with enhanced MHC-B downregulat

191 onventional methods for detecting pharyngeal carriage of Neisseria meningitidis are complex.

192 reduced-function OCT1 alleles compared with carriage of one or no deficient allele (OR 2.41 [95% CI

193 Nasopharyngeal carriage of PCV7 and 23vPPV serotypes was similar among

194 Nasopharyngeal carriage of PCV7 serotypes in Group 1 was significantly

195 ics, administered either in T1 or T2, on the carriage of penicillin-resistant VGS.

196 iant-specific antibody titers and subsequent carriage of pneumococcus expressing a particular antigen

197 Reduced susceptibility to chlorhexidine and carriage of qacA or qacB were rare among MRSA isolates i

198 We compared the phenotype, carriage of reduced-function OCT1 variants, and concomit

199 The minor allele carriage of rs174448 was associated with lower d2 Test o

200 Outcomes included carriage of S. aureus, methicillin-resistant S. aureus (

201 type replacement but did not influence total carriage of S. pneumoniae, H. influenzae, or S. aureus.

202 he intestine is crucial for the survival and carriage of Staphylococcus aureus, a common colonizer of

203 eages that were strongly associated with the carriage of stx2a produced comparatively more Stx on ave

204 en together, our data provides evidence that carriage of the ATC/TTC haplotype in itself may increase

205 In parallel, analyses of H. pylori status, carriage of the cag pathogenicity island and assignment

206 n of H. pylori phylogeographic population or carriage of the cagPAI with microbiota composition.

207 l, shock [odds ratio (OR) 26.0, P= 0.02] and carriage of the CATT7 allele (OR 5.12,P= 0.04) were the

208 firm the strength of the association between carriage of the HLA-B*53:01 allele and raltegravir-induc

209 n species variation can substantially affect carriage of the major conjugative plasmids.

210 tors, and examples that promote asymptomatic carriage of the organism.

211 Carriage of the rs1295686 variant A allele was also asso

212 In response, the current study surveyed carriage of the tpeL gene among different C. perfringens

213 We show that murine carriage of this organism occurs in the bowel and nares,

214 ] 1.63 [95% CI 1.22-2.17], P = 0.001) as was carriage of two reduced-function OCT1 alleles compared w

215 clinical manifestation from the asymptomatic carriage of typhoidal Salmonella.

216 anding of the host genetic susceptibility to carriage of, and infections, due to Staphylococcus aureu

217 Carriages of the CATT7 and -173 C high-expression MIF al

218 The effect of thalassemia carriage on hepcidin is also unknown, but it could be re

219 f carbapenemase-producing Enterobacteriaceae carriage on patient outcome in two Greek ICUs with carba

220 t specimens, which may indicate asymptomatic carriage or a less severe syndrome, such as upper respir

221 B-FHbp does not rapidly reduce meningococcal carriage or prevent serogroup B carriage acquisition.

222 ns unknown whether this vaccine will prevent carriage or transmission, key aspects in long-term vacci

223 stently the opposite for rs1535 minor allele carriage (P < 0.05).

224 a 73% (95% CI 24-90) reduction in gametocyte carriage (P = .013).

225 , H. influenzae, and S. aureus polymicrobial carriage patterns do not result from confounding by age

226 We show that duration of carriage plays such a role, with long duration of carria

227 vaccine/nonvaccine serotypes in invasive and carriage pneumococcal surveillance and contribute to fut

228 Whereas upper respiratory tract carriage precedes disease for both pathogens, interactio

229 Livestock-associated S. aureus nasal carriage predominated among IHO workers.

230 We investigated ABR S. aureus nasal carriage prevalence among adults with versus without occ

231 meningococcal and genotypically serogroup B carriage prevalence among sampled students were stable,

232 derable global variation in the pneumococcal carriage prevalence has been observed and the ecological

233 Nasopharyngeal carriage prevalence of pneumococcus was monitored in pro

234 ge but no further significant differences in carriage prevalence of the four bacterial species compar

235 Carriage prevalence on campus remained stable, suggestin

236 Georgia high school students, meningococcal carriage prevalence was 7%.

237 S. aureus nasal carriage prevalence was higher among IHO (53%) compared

238 Nasal carriage prevalence was higher among IHO compared with C

239 MDRSA nasal carriage prevalence was similar among IHO workers and CR

240 e interval (CI): 1.07, 1.83], but MRSA nasal carriage prevalence was uncommon (2-3%) in IHO and CR ad

241 d invasiveness (disease incidence divided by carriage prevalence) had similar patterns in children an

242 n density of other species and H. influenzae carriage prevalence.

243 sociated with decreased total or serogroup B carriage prevalence.

244 matic approach to estimate the potential for carriage prevention against antigenically diverse Neisse

245 their long-term correlation with disease and carriage prevention.

246 complemented mutants, DeltaespZ mutant fecal carriage progressively decreased on subsequent days.

247 of the human nasopharynx, with asymptomatic carriage providing the reservoir for invasive, disease-c

248 context and does not affect the pneumococcal carriage rate in this age group.

249 Median nasal carriage rate of S aureus in health-care workers at 4-we

250 asopharyngeal pneumococcal serotype-specific carriage rates at age 9 months in each study group.

251 usted odd ratios (ORs) for serotype-specific carriage rates by presence of specific viruses were calc

252 MRSA hand carriage rates in patients, nurses, and dentists were 9.

253 Meningococcal carriage rates in US high school students were lower tha

254 In this group, meningococcal carriage reduced from 24.2% (36/149) at inoculation to 1

255 ering density of pneumococcal nasopharyngeal carriage, reducing phagocytic killing, and resulting in

256 No carriage reduction was observed over time or with more M

257 However, pneumococcal carriage remained comparable due to an expansion of non-

258 equenced 2283 MRSA isolates (detected during carriage screening and in clinical samples) from 1465 in

259 Participants were tested for nasal S. aureus carriage, serum total IgE and specific IgE to SEs, and f

260 ever, even in asymptomatic people, a Babesia carriage state can be established that can last up to a

261 rsistent and non-persistent gastrointestinal carriage states in genetically identical mice.

262 and used to predict diagnosis, APOE epsilon4 carriage status, cerebral blood flow, cerebrospinal flui

263 rains with low level of virulence similar to carriage strains are most frequently responsible for IMD

264 o 12 different clonal complexes belonging to carriage strains.

265 nd binding activity compared to normal nasal carriage strains.

266 ld be useful for density measurement and for carriage studies in areas with limited resources.

267 his approach could improve the efficiency of carriage studies.

268 the best pneumococcal serotyping methods for carriage studies.

269 A carriage study was undertaken (n = 112) to ascertain the

270 cimens and completed questionnaires during 4 carriage surveys over 11 months.

271 Twenty cross-sectional carriage surveys were conducted in 7 countries in the Af

272 posure is a risk factor for developing fecal carriage that may lead to nosocomial infection.

273 nfection (CDI) and asymptomatic C. difficile carriage, the diagnostic predictive value of NAATs is li

274 In volunteers who did not develop carriage, the number of circulating 6BPS memory B cells

275 is associated with maternal rectovaginal GBS carriage, the single most important risk factor for GBS

276 umococcal serotype-specific progression from carriage to disease before and after rollout of PCV7/13,

277 tanding of disease transition from bacterial carriage to infection with the pneumococcus serving as a

278 and non-vaccine pneumococcal serotypes from carriage to OM before and after vaccine rollout.

279 lves from one of asymptomatic nasopharyngeal carriage to overt disease.

280 ble asymptomatic pneumococcal nasopharyngeal carriage to pneumonia and invasive disease.

281 We investigated polymicrobial carriage using longitudinal data from 369 Bedouin childr

282 We explored whether measuring pneumococcal carriage was a useful surrogate for monitoring postvacci

283 Protection from carriage was associated with a high number of circulatin

284 t higher pretest risk of pathogenic mutation carriage was defined according to genetic testing guidel

285 Nasopharyngeal H influenzae type b carriage was detected in one (0.2%) of 623 children youn

286 Meningococcal carriage was highest in 24- to 39-year-olds (45%, n = 9/

287 of N. lactamica or were sham-inoculated, and carriage was monitored for 26 weeks, after which all par

288 Carriage was more frequent in individuals aged 5-14 year

289 The inhibition of meningococcal carriage was only observed in carriers of N. lactamica,

290 alence of vaccine-serotype (VT) pneumococcal carriage was predictive of the relative change in incide

291 SE sensitization, but not S. aureus carriage, was associated with poly-sensitization to food

292 ropharyngeal swab cultures for meningococcal carriage were performed 3 times during the school year.

293 ity can drive meningococcal transmission and carriage, which likely facilitated the persistence of ST

294 at factors determining bacterial duration of carriage will also affect the prevalence of resistance.

295 hanisms maintaining diversity in duration of carriage will also maintain diversity in antibiotic resi

296 -mosquito infection due to frequent parasite carriage with higher densities of parasites (often detec

297 Immunization effectively prevented carriage with only 1 of 4 single antigen-matched strains

298 s vaccine trials, suggesting interference of carriage with T-cell immunity.

299 gate vaccines, aim to eliminate asymptomatic carriage with vaccine-type pneumococci.

300 We hypothesized that while asymptomatic carriage would not increase the risk of chronic lung all