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1 ine production from innate immune cells, but cast doubt on a different study, which suggests that thi
3 equency, detectable regulatory polymorphisms cast doubt on a model in which cis-acting variation is a
4 ults, which contradict previous evidence and cast doubt on a widely accepted model for the mtPTP, war
5 ily of transcription factors are infrequent, casting doubt on a direct role for E2Fs in driving cance
6 sults are observed with ectopic plakoglobin, casting doubt on a normal role for plakoglobin in axis s
9 This observation has sometimes been used to cast doubt on applicability of the Turing mechanism to c
13 ognising abstract shapes, a conclusion which casts doubt on cognitive explanations of fly behaviour i
15 s mitral regurgitation in cardiomyopathy and casts doubt on FMR being purely "functional" in etiology
16 be accommodated in the H. habilis holotype, casting doubt on H. rudolfensis as a biologically valid
17 The difficulties inherent in such controls cast doubt on how effective miRNAs are in driving phenot
18 rowth habit and wall strength of mur2 plants casts doubt on hypotheses regarding roles of xyloglucan
21 er for prostate cancer, further studies have cast doubt on its utility to diagnose this condition.
25 with hypertrophic or dilated cardiomyopathy, casting doubt on its acceptance as a distinct disease en
26 a natural amphi-North Atlantic distribution, casting doubt on its non-native status in the NW Atlanti
29 of large collaborative outcome studies have cast doubt on many traditional 'common sense' practices.
30 s of rare familial forms of the disease have cast doubt on our understanding of the role of genetics
32 resented by phenyl to naphthyl substitution, casting doubt on previous reports of predicted binding o
33 -positive cells in standard assay conditions casts doubt on previous inferences that the vast majorit
34 (HGT) between distantly related rrn operons casts doubt on reconstructions of phylogenetic relations
35 se source localisation techniques, therefore casting doubt on reported differences in brain generator
39 r-like cells in the slug posterior, however, cast doubt on that ability, and more recent experiments
40 ssociated with shear thinning and thickening cast doubt on that conclusion and leave unsettled whethe
42 rther research on spontaneous transformation cast doubt on that interpretation, and motivated re-exam
43 ndividual from subsequent infections and has cast doubt on the ability to develop effective vaccines.
44 spheres are of malignant origin, our results cast doubt on the assumption that adherent tumor-derived
47 results from a large multi-center study have cast doubt on the benefit of the broad application of hy
48 e functional consequences of their mutations cast doubt on the causal role of NL4 mutations in these
50 teraction between storage medium and filler, cast doubt on the clinical relevance of in vitro studies
51 ormalized left ventricular ejection fraction cast doubt on the complete reversibility of this conditi
54 pre-travel advice on malaria prevention, but cast doubt on the effectiveness of current strategies to
57 ory and experiment in these paradigm systems cast doubt on the existence of LBHBs, as currently defin
58 mportance of temporal discharge patterns and cast doubt on the functional significance of call-select
62 ally distal environmental factors, then they cast doubt on the hypothesis that such factors have larg
64 idely among different leukemia specimens but cast doubt on the hypothesis that this variation is a ma
65 ld-type in phenotype [7]; these two findings cast doubt on the idea of a function for activin in earl
66 gnificant proliferative capacity in vivo and cast doubt on the idea that adult stem cells have a sign
67 required for meiosis in the genome has also cast doubt on the idea that Giardia is primitively asexu
69 hough recent findings by several groups have cast doubt on the importance of canonical disulfide pair
73 entists conducted research which appeared to cast doubt on the link between smoking and p53 mutations
74 eam (GS) to the subpolar gyre (SPG) and have cast doubt on the mechanism underlying an apparent pathw
76 spective epidemiological data in humans have cast doubt on the possibility of a strong relationship.
77 create human liver diseases in mice, and has cast doubt on the potential of iPSC-Heps for liver cell
81 er hand, several arguments have emerged that cast doubt on the relevance of EF effects as a conceptua
82 ermination of metazoan lifespan, but they do cast doubt on the robustness of the previously reported
89 ot from activation of the death pathway, and cast doubt on the utility of anti-apoptotic therapies to
90 l edema and subsequent anatomic changes have cast doubt on the utility of edema-weighted MR imaging a
91 tism in the phase diagram has for many years cast doubt on the validity of conventional models of mag
93 ugated) genistein in certain strains of mice cast doubt on the value of the use of these rodents for
94 level in the Veterans Health Administration cast doubt on the value of using 30-day RSMRs as a means
97 n vary widely within and among lineages have cast doubts on the existence of a single "molecular cloc
98 sediments, but lower opal accumulation rates cast doubts on the importance of the EEP as an oceanic r
100 re was no such expansion in the simulations, casting doubt on the accuracy of methods that infer demo
101 lation of viral mutagens has been difficult, casting doubt on the clinical viability of this strategy
102 n of the phenyl ring interaction to binding, casting doubt on the extent of the cation-pi effect.
103 he former can be retrieved associatively and casting doubt on the general consolidation hypothesis.
104 de of replication occurs in tissues, thereby casting doubt on the general validity of the "orthodox,"
105 about sensory and motor variables is small, casting doubt on the hypothesis that correlations betwee
106 s in single-crystal absorbance measurements, casting doubt on the idea that ground state conformation
107 ne) even 24 h beyond a single exercise bout, casting doubt on the importance of nutrient timing vs. s
108 ed in two of the three BLUF domains studied, casting doubt on the importance of the formation of a po
109 cross a wide variety of tasks code modality, casting doubt on the notion that these regions embody a
110 ed in most cases after performing nested PCR casting doubt on the physiologic relevance of these spli
111 ne is not conserved between mouse and human, casting doubt on the proposed function of this proline r
112 eported within myelinated tracts of the CNS, casting doubt on the role myelin-associated inhibitors p
113 press binding sites for factor VIII (fVIII), casting doubt on the role of exposed PS as the determina
114 ten found after more intense nerve activity, casting doubt on the role of rapid endocytosis at synaps
115 biogeographical differences between species, casting doubt on the speculation that the spectral sensi
116 c/dysoxic events did not affect seep faunas, casting doubt on the suggested anoxic nature and/or glob
117 n patterns in the circulation or in tissues, casting doubt on the usefulness of plasma nitrite/nitrat
118 was observed on nonhuman primate cell lines, casting doubt on the utility of nonhuman primates as mod
119 P assay conditions has never been published, casting doubt on the validity of previous calibrations.
120 ffects as the source of the catalytic power, casting doubt on the validity of the electrostatic idea,
122 ed the HCO(3)(-)-dependent oxidation of DCF, casting doubt on the validity of using DCF oxidation as
123 hat most NETs resemble intergenic sequences, casting doubts on the quality of such UniGene clusters.
124 mpR (OmpR-P) is unable to bind to EnvZ, thus casting doubts on the role of the EnvZ phosphatase activ
127 considered to be important for those models, casts doubt on the current hypothesised mechanisms of ex
128 e of cervical loss of tooth structure, which casts doubt on the currently popular concept of abfracti
131 interpretation of data from previous studies casts doubt on the existence of sympathetic vasodilator
133 assumption creates an obvious confound that casts doubt on the feasibility of first-spike latency co
134 modulate short-term glucose homeostasis, but casts doubt on the general usefulness of the inhibition
135 etectable expression in the germ line, which casts doubt on the generality of the duplication model.
139 ct role in the etiology of this disorder and casts doubt on the previously proposed role of this prot
140 erably larger than previously recognized and casts doubt on the reliability of A(I) estimation by sur
141 nitiated or spontaneous vocalizations, which casts doubt on the role of the frontal cortex of the Old
142 oxemia in the portal blood of trauma victims casts doubt on the role of the gut in the generation of
143 A recent report, using transgenic mice, casts doubt on the specificity of three antibodies commo
144 ciences and from clinical research, however, casts doubt on the validity of such criteria for clinica
145 the basal liverwort lineage Haplomitriopsida casts doubt on the widely held view that Glomeromycota f
147 -income backgrounds, but recent studies have cast doubt on their ability to substantially increase th
164 t function for Rhomboid, an observation that casts doubt on this prevailing model of Rhomboid functio
166 ting the findings to human (patho)physiology casts doubt on using a single strain to address many que
168 is only at z = 3.2, and recent results have cast doubt on whether dust and molecules can be found in
169 ce sizes required to generate these dynamics cast doubt on whether they might be observable in annual
171 environment selects"[4, 5], this hypothesis casts doubt on whether geographic divergence promotes sp
172 bias compared with the other methods, which casts doubt on whether its reconstructions should be fav
174 otherwise nearly normal in its development, casting doubt on xyloglucan's role in wall structure.
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