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1 and seed development was limited to leucine catabolism.
2 e as a coactivator of epidermal triglyceride catabolism.
3 s, markedly increasing glucose and glutamine catabolism.
4 GI-58) are limiting in cellular triglyceride catabolism.
5 ptake, de novo synthesis, and muscle protein catabolism.
6 ng enhanced potential abilities of microbial catabolism.
7 riptional regulation from stress response to catabolism.
8 bolic processes and environments beyond DMSP catabolism.
9 riggers auxin biosynthesis, conjugation, and catabolism.
10 chondrocyte hypertrophy and cartilage matrix catabolism.
11 he committed enzymatic step in homogentisate catabolism.
12 tabolic phenotype with lactate and glutamine catabolism.
13 proteins implicated in transcription and RNA catabolism.
14 ed cellular FAEE hydrolase activity and FAEE catabolism.
15 function, retinoid metabolism, and nicotine catabolism.
16 acids, reflective of lipid mobilization and catabolism.
17 armacokinetic properties, particularly their catabolism.
18 eads to a metabolic switch from anabolism to catabolism.
19 rFGF1 is independent of its effect on lipid catabolism.
20 ggesting that rFGF1 stimulates hepatic lipid catabolism.
21 gh His and makes Zn bioavailable through His catabolism.
22 rge set of genes responsible for cholesterol catabolism.
23 ins, particularly LDL, by accelerating their catabolism.
24 cterize putative hydrolases involved in FAEE catabolism.
25 compound Torin 2, which inhibits hemoglobin catabolism.
26 HIBCH is unique to valine catabolism.
27 agliflozin raises LDL levels through reduced catabolism.
28 sponsible for the rate-limiting step in BCAA catabolism.
29 genetic evidence for their function in BCAA catabolism.
30 (COMT), regulating catechol neurotransmitter catabolism.
31 ammonia-lyase in the first step of histidine catabolism.
32 derived from an intermediate of l-isoleucine catabolism.
33 than acidifying it, as occurs after dextrose catabolism.
34 ry peroxisomal fat oxidation, and amino acid catabolism.
35 ally ill patients are susceptible to protein catabolism.
36 egulates bile acid synthesis, transport, and catabolism.
37 enesis, fatty acid synthesis, and amino acid catabolism.
38 inflammatory milieu also stimulates protein catabolism.
39 and transduction, metabolism, transport and catabolism.
40 as a consequence of increased IR and protein catabolism.
41 e surgical stress response and postoperative catabolism.
42 VC(R)-MMAE catabolite generated by lysosomal catabolism.
43 hree emergent co-culture properties: ethanol catabolism, a distinct volatile profile, and yeast popul
45 nurenine, a metabolite related to tryptophan catabolism, also impairs memory CD4 T-cell survival and
48 directly, in concert with MMPs, in collagen catabolism and clearance and is an important factor in r
49 In livers of mice, FXR regulates amino acid catabolism and detoxification of ammonium via ureagenesi
50 e treated with SnPP exhibited decreased heme catabolism and diminished iron release as well as reduce
51 ta (PPARD) has essential roles in fatty acid catabolism and energy homeostasis as well as cell differ
54 ration and viability, a shift towards matrix catabolism and increased expression of proinflammatory c
56 as heat shock proteins, abscisic acid (ABA) catabolism and its signalling pathway, lipid metabolism
57 ic effects through increased LDL cholesterol catabolism and LDL-derived cholesterol fecal excretion a
58 ng implantation, we directly observe protein catabolism and macropinocytosis in situ by pancreatic ca
66 xtracellular arginase, resulting in arginine catabolism and reduced levels of total brain arginine.
67 o cells in vivo, exhibit decreased glutamine catabolism and reduced reliance on glutamine anaplerosis
68 s mobilized from lean tissues during protein catabolism and results in acute increases in circulating
69 lly suppressed markers of hepatic amino acid catabolism and reversed the illness-induced hypoaminoaci
71 in the expression of cytokinin biosynthesis, catabolism and signaling genes in response to infection
72 proteolysis, lipolysis and amino acid/lipid catabolism and significantly increases the cheese matura
74 moter region of genes involved in methionine catabolism and that this binding affects histone modific
75 evidence that the LDLR plays a role in Lp(a) catabolism and that this process can be modulated by PCS
76 apture of electrons generated from substrate catabolism and thus increase substrate-to-product yields
78 n tumor cells abrogates tumor-induced muscle catabolism and wasting in cultured myotubes and in mice.
79 age-specific lipid metabolism and amino acid catabolism, and a dendritic-cell-specific program of reg
80 pling, but instead is coupled with ascorbate catabolism, and controls the synthesis of the moss cutic
81 is linked with bone demineralization, muscle catabolism, and higher risks of CKD progression and mort
82 tty acid oxidation and membrane phospholipid catabolism, and impairs recruitment of Akt to the plasma
83 associated with significant weight loss and catabolism, and negatively impacts quality of life (QL).
84 ism, fatty acid beta-oxidation, phospholipid catabolism, arachidonic acid and linoleic acid metabolis
85 l of PPARalpha, the genes required for lipid catabolism are transcribed before birth so that the neon
86 while branched-chain amino acid and proline catabolism are very old mitochondrial functions particul
87 enrichment points to differences in protein catabolism as one major source of clock variation in hum
88 1 (Drp1), thus inhibiting insulin and Abeta catabolism as well as hyperactivating mitochondrial fiss
89 muscle wasting by directly activating muscle catabolism as well as stimulating an innate immune respo
90 activity of enzymes involved in Trp and Arg catabolism, as well as to investigate amino acid catabol
91 e to different stimuli modulating amino acid catabolism, as were cytokine secretion levels and regula
92 probably not caused by defective pyrimidine catabolism but by the accumulation of pyrimidine catabol
94 ing insight into the mechanism of host lipid catabolism by an M. tuberculosis enzyme, augmenting our
95 ed to validate the role of FXR in amino acid catabolism by gene expression and metabolomics studies.
96 ophs, mechanisms for how their organotrophic catabolism circumvents thermodynamic restrictions remain
98 rsisting inflammation, immunosuppression and catabolism contributes to many of these adverse clinical
99 vely, these results indicate that asparagine catabolism contributes to S Typhimurium virulence, provi
100 nflammatory processes, including vitamin B-6 catabolism, could explain such findings.We investigated
101 SAT1 is a rate-limiting enzyme in polyamine catabolism critically involved in the conversion of sper
102 E) synthesis, and to a moderate induction of catabolism (CsCYP707A, an ABA 8'-hydroxylase) and buildu
103 t strongly induced both ABA biosynthesis and catabolism (CsNCED1, 9-cis-neoxanthin epoxycarotenoid di
104 cessary and sufficient to increase glutamine catabolism, defining important determinants of glutamine
105 As it progresses, the massive macromolecular catabolism dismantles the chloroplasts and, consequently
106 atio (PAr), a proposed marker of vitamin B-6 catabolism during activated cellular immunity, as predic
109 well as improved metabolic capacity and fuel catabolism during prolonged elevated energy requirements
110 bolism, as well as to investigate amino acid catabolism effects on the immune system of multiple scle
112 ch glycogen synthesis is blocked, and xylose catabolism enabled through the introduction of xylose is
113 siology (e.g. coordination of carbon uptake, catabolism, energy and redox production, and growth), wh
116 effective detoxification system for acylate catabolism exists in DMSP-catabolizing Roseobacters.
117 ritical illness increases hepatic amino acid catabolism, explaining the illness-induced hypoaminoacid
119 es revealed positive correlations among BCAA catabolism genes in stress, development, diurnal/circadi
120 further characterized one of the chlorophyll catabolism genes, Stay-green (SGR), and demonstrated tha
122 ry chain oxidoreductases from central carbon catabolism (glycolysis and TCA cycle), and was controlle
123 hways in all major branches of biosynthesis, catabolism, gut microbiome activities, and xenobiotics.
124 peared to have stronger effects on liver fat catabolism (Hadh) and synthesis (Fasn) than exercise.
127 amine oxidase (hDAO), required for histamine catabolism, has multiple N-glycosylation sites, but thei
130 activity of enzymes involved in Trp and Arg catabolism (IDO1, IDO2, Trp 2,3-dioxygenase [TDO], argin
131 ncluded 3 transcripts involved in tryptophan catabolism (IDO1, KMO, KYNU) that play a pivotal role in
132 2 metabolic programming by altering arginine catabolism, impairing polyamine biosynthesis and reducin
134 at in pericentral hepatocytes) and glutamine catabolism in (periportal) hepatocytes represents the hi
136 ns revealed unique and specific l-malic acid catabolism in ABSA 1014 that was absent in UPSA 807.
137 proteins resembling enzymes involved in BCAA catabolism in animals, fungi, and bacteria as well as pr
138 y is the major route of L-tryptophan (L-Trp) catabolism in biology, leading ultimately to the formati
141 ata demonstrate that disruption of normal HA catabolism in Hyal2(-/-) mice causes increased HA, which
143 ngs highlight the pivotal role of amino acid catabolism in muscle fatigue and type 2 diabetes pathoge
145 ses autophagy in AT and contributes to lipid catabolism in other cells, it was proposed that autophag
149 sults highlight the importance of amino acid catabolism in the modulation of the immunological respon
150 s the cou genes, encoding p-hydroxycinnamate catabolism in the soil bacterium Rhodococcus jostii RHA1
153 OH) primarily through two steps of oxidative catabolism in which alcohol dehydrogenase (ADH) and alde
155 nase (IDO), an enzyme involved in tryptophan catabolism, in macrophages and in the lungs of animals (
156 on sources that do not produce NADH in their catabolism, including acetate and the amino acids glutam
157 d in amino acid and fatty acid transport and catabolism, indicating metabolic adaptation to a differe
161 bolism but by the accumulation of pyrimidine catabolism intermediates reaching toxic concentrations.
165 synthesis of carotenoids, whereas carotenoid catabolism involves a multitude of nonenzymatic and enzy
166 The limiting step in intracellular glutamine catabolism involves its conversion to glutamate by gluta
170 es robust evidence that increased vitamin B6 catabolism is independently associated with a higher ris
175 hes, we reveal that the capacity for choline catabolism is widespread in marine heterotrophs of the m
176 tonia, PDE10A, a key enzyme in cAMP and cGMP catabolism, is downregulated in striatal projections to
177 H) which disturb lysine (Lys) and tryptophan catabolism leading to neurotoxic accumulation of glutari
178 ipa), the enzyme required for lysosome lipid catabolism, leads to AT atrophy and severe hepatic steat
179 Hpd excision successfully reroutes tyrosine catabolism, leaving treated mice healthy and asymptomati
181 Therefore, new therapies that suppress heme catabolism may be beneficial in ameliorating the anemia
182 n of Th cell growth by SF through tryptophan catabolism may play an important role in preventing inap
183 rivation, HIF-1 activation down-modulates LD catabolism mediated by adipose triglyceride lipase (ATGL
184 ellular membranes; these included nucleotide catabolism, membrane lipid breakdown and increased creat
185 ression of gene expression related to purine catabolism, methionine and S-adenosylmethionine biosynth
186 in genes involved in vitamin D anabolism and catabolism might be of importance in VKH pathobiology.
188 tegic provision of specific nutrients, whose catabolism modulates conditions like pH or anoxia in the
189 ced stomatal opening is delayed in three TAG catabolism mutants (sdp1, pxa1, and cgi-58) and in stoma
191 if this is due to increased muscular protein catabolism, obesity, and/or increased insulin resistance
192 Empagliflozin significantly reduced the catabolism of (3)H-cholesteryl oleate-labeled LDL inject
198 ferases (BCAT) are enzymes that initiate the catabolism of branched-chain amino acids (BCAA), such as
200 ol "housekeeping" enzyme responsible for the catabolism of canonical and noncanonical nucleoside trip
203 al approaches to discover novel pathways for catabolism of d-threitol, l-threitol, and erythritol.
204 We investigated the compartmentation of the catabolism of dodecanedioate (DODA), azelate, and glutar
207 t can be obtained through the scavenging and catabolism of extracellular protein via macropinocytosis
212 ctivated receptor (PPAR)-alpha signaling and catabolism of fatty acids (FAs) when simultaneously subj
214 ted pathway analysis revealed that increased catabolism of fixed carbon stores, metabolic signaling,
217 ybenzoic acid and catechol, derived from the catabolism of gallotannins, ellagitannins, flavan-3-ols
220 a critical nodal role of PEPCKmt in linking catabolism of glucose and glutamine with anabolic pathwa
221 This glucose-induced excitation implies the catabolism of glucose, leading to a closure of ATP-sensi
222 of concept study showing that modulating the catabolism of glucosylceramide may be a therapeutic targ
224 nase-1 (HO-1), the rate-limiting step in the catabolism of heme into the bioactive signaling molecule
232 roxisomes is necessary for the synthesis and catabolism of lipids, the trafficking of cholesterol, an
233 lieu, as exemplified by the distinct glucose catabolism of macrophages exposed to LPS/IFN-gamma or IL
234 rts sulfur and one-carbon metabolism and the catabolism of odd-chain fatty acids, branched-chain amin
239 ation, early seedling growth is supported by catabolism of stored reserves of protein, oil or starch
242 involved in degradation of arabinoxylan and catabolism of the released l-arabinose and d-xylose.
244 rea dissociation or myeloperoxidase-mediated catabolism of thiocyanate to free amino groups of protei
246 mab independently accelerated the fractional catabolism of VLDL-apoB (P<0.001 and P.032, respectively
250 uman osteosclerosis, inhibition of glutamine catabolism or Gcn2 deletion suppressed excessive bone fo
251 ss results in major physiological and carbon catabolism pathway changes, including an 80% reduction i
252 o an impaired A. baumannii phenylacetic acid catabolism pathway, which led to accumulation of phenyla
253 wledge of the role branched-chain amino acid catabolism plays in seed development and amino acid home
254 This elevation indicates increased protein catabolism, possibly as an alternate energy source given
256 ks the regulation of fatty acid flux to BCAA catabolism, providing a mechanistic explanation for how
257 l proteins linked to autophagy and lysosomal catabolism reflecting vesicular transport obstruction an
260 are best described as foam cells, with lipid catabolism representing the main biological process and
261 are best described as foam cells, with lipid catabolism representing the main biological process, and
263 7, trauma patients showed increasing muscle catabolism: serine levels increased from 42.03 (31.20-54
264 no effect on monoamine oxidase A (serotonin catabolism), serotonin receptor 5-HT4, or mouse serotoni
266 Tor metabolic sensing pathway regulates yolk catabolism, similar to Tor-dependent metabolic regulatio
267 ession of rate-limiting enzymes in polyamine catabolism (SMOX, SSAT) and depleted cellular natural po
268 cause of inflammation-immunosuppression and catabolism syndrome is currently unknown, but there is i
269 ersistent inflammation-immunosuppression and catabolism syndrome may require a more complementary app
270 ersistent inflammation-immunosuppression and catabolism syndrome," and it is proposed here that this
273 accompanied by an increased ratio of glucose catabolism through glycolysis versus the tricarboxylic a
274 an important role in controlling pyrimidine catabolism through repression of DPYD expression, follow
275 te synthesis, suggesting involvement of BCAA catabolism through the IRG1/itaconate axis within the tr
276 we determined that WNT stimulates glutamine catabolism through the tricarboxylic acid (TCA) cycle an
277 -1 plays a critical role in regulating lipid catabolism to control the size of lipid droplets and pre
278 ve shown that C. albicans co-opts amino acid catabolism to generate and excrete ammonia, which raises
279 ES cells utilize both glucose and glutamine catabolism to maintain a high level of intracellular alp
281 n of the metabolic inputs that couple carbon catabolism to oxidative phosphorylation is a primary cau
283 directly or indirectly, to compromised sugar catabolism, to glycogen accumulation, and to distorted c
284 thus providing a novel link between protein catabolism, ureagenesis, and hepatic lipid metabolism.
285 -released cachexins directly activate muscle catabolism via activating TLR4 on muscle cells independe
286 tion on the peroxisomal versus mitochondrial catabolism was gathered from the labeling patterns of ac
290 ketogenesis and glucocorticoid-driven muscle catabolism, which are prevented by increasing food intak
291 tion is characterized by enhanced tryptophan catabolism, which contributes to immune suppression and
292 SMS deficiency leads to excessive spermidine catabolism, which generates toxic metabolites that cause
293 ing effector function by engaging fatty acid catabolism, which is promoted by fenofibrate and synergi
294 r the role of autophagy in hepatocellular LD catabolism while implicating the small GTPase Rab7 as a
295 les and up-regulated genes involved in lipid catabolism, while decreasing 241 exercise-responsive gen
296 lucidation of the molecular mechanism of IPU catabolism will enhance our understanding of the microbi
297 reveal a mechanism that coordinates glucose catabolism with L-2HG synthesis, and establish the fly a
298 trongly dependent on mitochondrial substrate catabolism, with availability of NADPH as a major rate-c
299 isinin (DHA) was found to disrupt hemoglobin catabolism within 1 hour of exposure, resulting in a tra
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