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1 hich cytoplasmic proteins and organelles are catabolized.
2 even though the supplied EA was extensively catabolized.
3 garding the mechanisms by which factor Xa is catabolized.
4 esterol homeostasis, and, finally, how it is catabolized.
5 ocrine cycle, whereas the internalized Hb is catabolized.
6 s then deactivated by CYP24A1 and ultimately catabolized.
8 s genetically deficient in LRP, were able to catabolize (125)I-fVIII complexed with vWf, which was no
9 talk with the vitamin D-responsive gene that catabolizes 25-hydroxy-vitamin D and 1,25-dihydroxyvitam
11 concentrations of complexes, Th-PN1(K7E) was catabolized 5- to 10-fold less efficiently than Th-PN1,
14 owever, strains NCTC 8325 and N315 failed to catabolize acetate during the postexponential growth pha
15 ations can alter the ability of S. aureus to catabolize acetate, a surprising discovery, as TCA cycle
19 lase) constitute the majority of the sucrose-catabolizing activity; however, mutations in any one of
22 apyrase that inhibits platelet activation by catabolizing ADP released from damaged tissues and blood
25 owth in human saliva and in their ability to catabolize alpha-glucans digested by purified human sali
26 ent a model whereby this enhanced ability to catabolize amino acids is responsible for the fitness ga
29 tend the previous evidence that BCAAs can be catabolized and serve as respiratory substrates at multi
31 argeting the metabolic pathways that import, catabolize, and synthesize essential cellular components
32 GlcNAc must be phosphorylated by Hxk1 to be catabolized, and also for it to enter the anabolic pathw
35 ]-Tyr4-bombesin was rapidly internalized and catabolized at 37 degrees C with approximately 10% of th
37 molecules found in vivo have been partially catabolized at either the E(1480)-(1481)G or E(1667)-(16
38 g-deficient PN1 variant, PN1(K7E), should be catabolized at the same rate as complexes formed with na
43 ites taken up by proliferating cells are not catabolized, but instead are used as building blocks dur
45 a highly toxic by-product of metabolism, is catabolized by a limited number of bacterial species uti
47 ptide hormone released by adipocytes, can be catabolized by adipose angiotensin-converting enzyme 2 (
48 ese results demonstrate that 15d-PGJ2 can be catabolized by Aor, thereby attenuating subsequent Nrf2
49 torage organelles that in hepatocytes may be catabolized by autophagy for use as an energy source, bu
50 per year(1,2), an estimated 10% of which is catabolized by bacteria through the DMSP cleavage pathwa
51 structurally diverse aromatic compounds are catabolized by bacteria to form benzoyl-coenzyme A (benz
58 low-glucose and hypoxic conditions, proline catabolized by POX was used preferentially for ATP produ
61 o studies in mice showed that 90% of Tac was catabolized by the kidney with a t1/2 of 1 h and a filtr
63 line, and associated organic acids) were not catabolized by the the frdA::cat(+) strain, indicating t
64 d previously that all-trans retinoic acid is catabolized by these oxidative enzymes, and that an inhi
71 a lysosomal machinery-dependent process that catabolizes cellular components/organelles and proteins
72 in the body do not express the capability of catabolizing cholesterol, so cholesterol efflux is essen
73 first time the capacity of adipose tissue to catabolize circulating BCAAs in vivo and that coordinate
76 s colonized by a dense community of microbes catabolizing dietary and host carbohydrates during their
79 Finally, we show that a mutant unable to catabolize dl-alanine displays decreased competitiveness
80 tial depletion of glycogen reserves which is catabolized during freezing to produce cryoprotective co
81 epatocytes reside on the sER, LDs can now be catabolized efficiently to provide triglyceride for lipo
82 ocess by which cytoplasmic organelles can be catabolized either to remove defective structures or as
86 S, with corresponding reduction of vitamin D catabolizing enzyme (24-hydorxylase) expression in the C
88 to identify inhibitors of S. mansoni NAD(+) catabolizing enzyme (SmNACE), a receptor enzyme suspecte
90 results establish FAAH-2 as a bone fide NAE-catabolizing enzyme and suggest that NAE inactivation is
92 oleamine 2,3-dioxygenase (IDO), a tryptophan-catabolizing enzyme expressed by trophoblasts and macrop
94 B cell-intrinsic induction of the tryptophan-catabolizing enzyme IDO1 is a key mechanism limiting TI
95 e by a mechanism dependent on the tryptophan catabolizing enzyme indoleamine 2,3 dioxygenase 1 (IDO1)
98 induced splenic expression of the tryptophan catabolizing enzyme indoleamine 2,3-dioxygenase (IDO).
99 -gamma) induces expression of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO1) i
100 ata, is a potent inhibitor of the tryptophan catabolizing enzyme indoleamine-2,3-dioxygenase (IDO).
103 ybrid screening, we identified the polyamine catabolizing enzyme spermidine/spermine N(1)-acetyltrans
104 airway smooth muscle localizes the polyamine catabolizing enzyme spermidine/spermine N1-acetyltransfe
105 2,3-dioxygenase (IDO1) is a tryptophan (Trp)-catabolizing enzyme which is assumed to be instrumental
106 gs, increased colonic expression of the atRA-catabolizing enzyme, CYP26A1, correlated with reduced fr
108 ation of CYP26A1, a major retinoic acid (RA)-catabolizing enzyme, has recently been shown in cancer.
118 lternatively, the function of NACE may be to catabolize extracellular NAD(+) to prevent its use by ho
119 eria may be highly active protein degraders, catabolizing extracellular peptides while recycling nitr
121 d that the iron storage protein ferritin can catabolize folate in vitro and in vivo, and increased he
122 cytes overinduced heme oxygenase-1 (HO-1) to catabolize free heme in building up defense against this
123 of breast-to-brain metastases to take up and catabolize GABA into succinate with the resultant format
125 nd 4 have important roles in CNS function by catabolizing gangliosides and preventing their storage i
129 ypic effect on the ability of the variant to catabolize glucose, consistent with a modification in th
137 g fetal lung development and that failure to catabolize glycogen in the gsd/gsd rat is related to an
141 pathogenic bacterium Neisseria meningitidis catabolizes heme for the iron necessary for infection.
143 eme oxygenase 1 (Hmox1; EC 1.14.99.3), which catabolizes heme to biliverdin, carbon monoxide, and fre
144 eme oxygenase 1 (Hmox1; EC 1.14.99.3), which catabolizes heme to biliverdin, carbon monoxide, and fre
145 ively express heme oxygenase-1 (HO-1), which catabolizes heme to generate biliverdin, Fe(2+), and car
146 ucible enzyme heme oxygenase-1 (HO-1), which catabolizes heme to generate biliverdin, Fe(2+), and car
150 IgG protection receptor (FcRn) and therefore catabolize IgG, including pathogenic IgG autoantibodies,
153 and protein stores available in autumn were catabolized in proportion to their availability above a
155 that the essential amino acid tryptophan is catabolized in the tumor tissue by the rate-limiting enz
156 Because a large amount of the IGF-I was catabolized in vivo, we also studied the catabolism of I
158 ranscription microarray results, D-serine is catabolized into acetate via the phosphotransacetylase (
161 cells (SCs), we found that autophagy, which catabolizes intracellular contents to maintain proteosta
162 cidating the pathway by which cholesterol is catabolized is necessary to understand the molecular mec
163 ulate glycine betaine for osmoprotection and catabolize it as a growth substrate, but how they regula
165 involving nonphosphorylated intermediates to catabolize L-arabinose via an L-arabinose dehydrogenase,
166 human malaria parasite Plasmodium falciparum catabolizes large quantities of host-cell hemoglobin in
168 propose that the excess PC thus generated is catabolized, leading to TG synthesis and steatosis by wa
170 train SYK-6 of the bacterium Sphingobium sp. catabolizes lignin-derived biphenyl via a meta-cleavage
174 d particulate matter but are also crucial in catabolizing lung surfactant, a lipid-protein complex th
177 sferase system (PTS) plays a central role in catabolizing many sugars; regulation is effected by phos
179 stridium difficile, use a common strategy of catabolizing microbiota-liberated mucosal carbohydrates
180 a variety of additional S-nitrosothiols were catabolized more readily by A4V SOD than by WT SOD.
181 edlings revealed that seed storage lipid was catabolized more slowly, long-chain acyl-CoA substrates
182 lthough more than 95% of incoming mannose is catabolized, most of the mannose released by intracellul
185 reductase/myo-inositol oxygenase (RSOR/MIOX) catabolizes myo-inositol and is implicated in the pathog
187 e and repressed when readily transported and catabolized nitrogen sources are available in the enviro
192 uestration into ischemic cerebral tissue, by catabolizing nucleotides released by injured cells, ther
199 constant (the fraction of the vascular pool catabolized per unit time), by external losses, and by r
203 ription of the genes needed to transport and catabolize poor nitrogen sources, a physiological proces
204 gs to a superfamily of Nudix hydrolases that catabolize potentially toxic compounds in the cell.
206 nt Bradyrhizobium japonicum strain unable to catabolize Pro (Pro dehydrogenase(-) [ProDH(-)]) resulte
207 inoculated with the mutant strain unable to catabolize Pro or take up H(2) (ProDH(-), hup(-)) than i
209 Salmonella enterica serovar Typhimurium LT2 catabolizes propionate through the 2-methylcitric acid c
211 s constitute the major cellular systems that catabolize proteins to recycle free amino acids for ener
212 umber of Gram-negative bacteria are known to catabolize quinate and shikimate, only limited informati
215 dividuals deposited reserves over winter and catabolized reserves over summer, mainly because regulat
218 se), the only enzyme in vertebrates known to catabolize S-adenosyl-L-homocysteine (SAH), an end produ
222 e double mutant acx1-1 acx2-1 were unable to catabolize seed storage lipid, and accumulated long-chai
223 sult in hypercolonization and the ability to catabolize serine represents a positive physiological tr
225 is a mammalian integral membrane enzyme that catabolizes several neuromodulatory fatty acid amides, i
226 ite observations that COMT is estrogenically catabolized, sex differences in its prefrontal repercuss
228 DL isolated from sPLA(2) transgenic mice was catabolized significantly faster than (131)I-HDL isolate
232 esemble two bacterial proteins that together catabolize substituted hydantoins, whose chemical struct
234 6390 confirmed that acetate was incompletely catabolized, suggesting that the ability to catabolize a
235 dipropyl triamines are clearly more actively catabolized than the corresponding methyl and ethyl syst
236 y Ti plasmid genes conferring the ability to catabolize that set of opines on the inducing Agrobacter
237 The inability of these mutant strains to catabolize the alanine provided in the medium interferes
239 eaminase (TD), act in the M. sexta midgut to catabolize the essential amino acids Arg and Thr, respec
240 expression of 15 genes encoding enzymes that catabolize the last half of the cholesterol molecule, re
241 although several classes of enzymes that can catabolize the latter two have been characterized, studi
242 major role of KatG in MTB pathogenesis is to catabolize the peroxides generated by the phagocyte NADP
243 lasts during early seed development and then catabolize the photosynthetic machinery during seed matu
244 holine kinase-alpha (CHKA), the enzymes that catabolize the products of EDI3 to determine which downs
249 enzyme that inhibits T-cell proliferation by catabolizing the essential amino acid tryptophan (Trp) i
251 xtracellular homopolymers of fructose and to catabolize these types of polymers is suspected to be a
252 , an enzyme subject to genetic polymorphism, catabolizes thiopurines into inactive methylated bases,
255 -hydroxyacid derived from 4-HNE) is primarly catabolized through a pathway that phosphorylates the C-
257 rts glutamine to glutamate, which is further catabolized through the tricarboxylic acid cycle for the
260 ate (epsilon-Ap(4)), respectively, which are catabolized to 1,N(6)-ethenoadenosine (epsilon-Ado) as t
263 vate or [(14)C]threonine, either of which is catabolized to [(14)C]acetyl-CoA in the mitochondrion.
264 lization, ADCs with noncleavable linkers are catabolized to amino acid-linker-warheads within the lys
267 H]GlcN, it was shown that these residues are catabolized to generate radiolabeled products that are u
268 rovide a better understanding of how DMSP is catabolized to generate the important climate-active gas
270 te, and acetoin, suggesting that glucose was catabolized to pyruvate that was then catabolized via th
271 n tissue samples, (3)H-DHT was predominantly catabolized to the 5alpha-androstane-3alpha,17beta-diol
272 de 2,4-dichlorophenoxybutyric acid, which is catabolized to the auxin 2,4-dichlorophenoxyacetic acid
273 chlorocatechol, respectively, which are then catabolized to tricarboxylic acid cycle intermediates vi
274 the ruminant nor the normal rumen flora can catabolize tricarballylate to ameliorate its toxic effec
277 ns of Haemophilus influenzae, the ability to catabolize tryptophan (as detected by indole production)
278 many tumors including gliomas constitutively catabolize tryptophan, it is unclear whether quinolinic
282 a component of the kynurenine pathway, which catabolizes tryptophan in mammals and certain bacteria.
283 n in activated monocytes and dendritic cells catabolizes tryptophan to kynurenine and other downstrea
284 We have identified tryptophanase (which catabolizes tryptophan to pyruvate and indole) as an Rcd
287 ver, certain tumor types that are capable of catabolizing tryptophan but are largely IDO-negative.
290 data showed that 125I-labeled des(1-3)IGF-I catabolized very fast, with a rapid appearance of nonpre
292 acids in pectin and xylan, respectively, are catabolized via committed metabolic pathways to supply c
296 se was catabolized to pyruvate that was then catabolized via the lactate dehydrogenase, pyruvate form
297 anoic acid (4,8-DHNA), which is subsequently catabolized via two parallel pathways we previously repo
299 , as a branched-chain amino acid, Leu can be catabolized within muscle, thus posing the possibility t
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