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1 position of the hydrogen peroxide residue by catalase).
2 s enzymes, superoxide dismutase 2 (SOD2) and catalase.
3 arrier, compared to the "dry" active site in catalase.
4 ss-induced DNA damage, which was reversed by catalase.
5 , signifying the presence of a highly active catalase.
6 ases with their backup systems as well as by catalase.
7 ression of manganese superoxide dismutase or catalase.
8 ch we achieved by expressing lower levels of catalase.
9 ished in the presence of polyethylene glycol-catalase.
10 downregulating the H2O2-inactivating enzyme catalase.
11 tantial increase in production of KatB, a Mn-catalase.
12 ugs in 7H9 broth-oleic acid albumin dextrose catalase.
13 a Compound II-like intermediate, similar to catalases.
14 structural dissimilarity with monofunctional catalases.
15 roxide (H2O2)-scavenging pathways, including catalases.
16 to that of the distal His in monofunctional catalases.
21 vehicle 74.6+/-4.1, L-NAME 37.0+/-2.0*, PEG-catalase 82.1+/-2.8; BIBR-1532 69.9+/-4.0, L-NAME 84.7+/
22 export, cells exhibit increased activity of catalase A (Cta1), the mitochondrial and peroxisomal cat
25 Our results reveal epigenetic silencing of Catalase, a key regulator of oxidative stress and DNA da
28 sent in the superoxidized manganese (III/IV) catalase active site is determined by comparing experime
29 owed that the liver superoxide dismutase and catalase activities (FA200), erythrocytes glutathione pe
31 tudy combines the use of glucose oxidase and catalase activities with the aim of rapid conversion of
33 Insulin-resistant iPSC also showed reduced catalase activity and increased susceptibility to oxidat
34 on-oxidizable phenylalanine exhibited higher catalase activity and less accumulation of off-pathway h
36 alis with heme increased growth and restored catalase activity but resulted in decreased survival in
37 imarily of Trp-321, and PxEDs stimulate KatG catalase activity by preventing the accumulation of inac
42 gentamicin-resistant SCVs displayed greater catalase activity than wild-type bacteria, which contrib
43 f the electron transport chain); 3) increase catalase activity that is involved in H2O2 breakdown; an
47 raction with O2 However, Rv2633c did exhibit catalase activity with a kcat of 1475 s(-1) and Km of 10
48 1 +/- 1.7 mm Cyanide and azide inhibited the catalase activity with Ki values of 3.8 mum and 37.7 mum
50 acity for maintaining potassium homeostasis, CATALASE activity, and reduced ASCORBIC ACID OXIDASE (AA
51 , inadequate activation of heme enzymes, low catalase activity, defective clearance of H(2)O(2) and a
53 ciated with reduction of both PPAR-gamma and catalase activity, which are reversed by both ACEA and t
59 ls more resilient toward ROS by coexpressing catalase along with a tumor specific chimeric Ag recepto
60 cistronic vector that concurrently expresses catalase, along with the CAR coexpressing catalase (CAR-
61 ion because pretreatment of eosinophils with catalase (an extracellular superoxide scavenger) or NSC
62 a reactive oxygen species (ROS) scavenger], catalase (an H2O2-degrading enzyme), myristoylated autoc
64 ified by mitochondria-targeted expression of catalase and a mitochondria-targeted peptide antioxidant
67 significantly improved superoxide dismutase, catalase and glutathione peroxidase activities in H2O2 t
68 ting defense mechanisms (increased levels of catalase and glutathione peroxidase expression), observe
69 ivator, Sulforaphane (SFN), augmented Prdx6, catalase and GSTpi expression in dose-dependent fashion,
70 hey showed increased levels of intracellular catalase and had a reduced oxidative state with less ROS
71 a functional complex on the promoters of the catalase and manganese superoxide dismutase (MnSOD) anti
72 iopsy specimens with 8Br-cGMP also activated catalase and manganese superoxide dismutase expression,
75 utant strain (DeltaMakatG1) showed decreased catalase and peroxidase activities and significantly inc
79 se an increase in the enzymatic (peroxidase, catalase and phenylalanine ammonium lyase (PAL)) and non
81 cted cells, with a decrease in the levels of catalase and PRDX6 in exosomes derived from HIV-1-infect
82 essions up-regulate the antioxidant proteins catalase and SOD and the antiapoptotic proteins Bcl-2 an
83 cells up-regulates the antioxidant proteins catalase and superoxide dismutase as well as the antiapo
87 pidaecin and defensin-1, stress-related gene catalase and two genes linked to memory formation, pka a
88 Initially, homocysteine reacts with native catalase and/or redox-active transition metal ions to ge
89 es including efflux pumps, ABC transporters, catalases and transcription factors, either directly or
90 tioxidant enzymes superoxide dismutase 1 and catalase, and activation of the pro-oxidant protein kina
91 ncreased liver glutathione peroxidase, serum catalase, and colon myeloperoxidase while decreasing tot
92 c is the first example of a non-heme di-iron catalase, and conclude that it is a member of a subset o
93 ression, such as Cu/Zn-superoxide dismutase, catalase, and glutathione peroxidase, but also significa
94 oduction, increased superoxide dismutase and catalase, and suppressed NADPH oxidase and reactive oxyg
95 on gene expression of toll-like receptor 4, catalase, and tumor necrosis factor-alpha significantly
96 ced activities of superoxide dismutase 2 and catalase, and were hypersensitive to hydrogen peroxide.
97 of extracellular vesicles containing active catalase; and 3) selective secretion of interleukin-6, i
100 Some enzymes (dehydrogenases, oxidase, and catalase) are valuable products with high conversion eff
101 MG-CoA synthase, aldehyde dehydrogenase, and catalase as the primary autoantigens, and glutamate dehy
102 drogenase 1, aldehyde dehydrogenase 1A1, and catalase, as well as the microsomal triglyceride transfe
103 acid and the enzymes glutathione reductase, catalase, ascorbate peroxidase and superoxide dismutase
105 irected expression of mitochondrial-targeted catalase at modest levels normalized mitochondrial ROS p
108 e efficiency of heme peroxidases compared to catalases can be directly attributed to the different di
109 es catalase, along with the CAR coexpressing catalase (CAR-CAT), performed superior over CAR T cells
110 nt response to different sizes of CeO2 while catalase (CAT) activity was not affected by either size
111 mutase (SOD) activity, associated with lower catalase (CAT) and ascorbate peroxidase (APX) activities
112 lent antioxidant capacity (TEAC) levels, and catalase (CAT) and glutathione peroxidase (GPx) activiti
113 Activities of superoxide dismutase (SOD), catalase (CAT) and peroxidase (POD) decreased at a later
114 utase (SOD), glutathione reductase (GR), and catalase (CAT) as well as levels of free radical damage
115 , we show that GLO physically interacts with catalase (CAT) in rice leaves, and that the interaction
116 - biosensor, which was fabricated by loading catalase (CAT) onto l-lysine/multiwalled carbon nanotube
121 st-mediated oxidant stress exposure, and its catalase contains oxidizable methionine (Met) residues.
122 not only do endogenous antioxidants such as catalase contribute to ROS-induced cell death, but also
123 whether the FoxO1 target antioxidant enzyme catalase contributes to sustained activation of Akt.
125 h inhibition by ULK2 also appears to involve catalase degradation and reactive oxygen species generat
127 ere we present the structure of bovine liver catalase determined from a single crystal at 3.2 A resol
130 nsform infrared (FTIR) spectra show that the catalase encapsulated in the PLL/f-MWCNT film can effect
131 oal of this study was to define the roles of catalase (encoded by hktE) and a bifunctional peroxiredo
133 roxide can be decomposed to oxygen by 0.44 U catalase enzyme and semiquantified in the range up to ap
137 H2O2 treatments induced the activity of catalase - especially for 2-day-old sprouts treated with
138 phosphorylation is associated with decreased catalase expression and increased fibronectin and PAI-1
141 ckdown cells, suggesting that RIP1 maintains catalase expression to restrain ROS levels in therapy re
143 nvolving inactivated FoxO1 and a decrease in catalase expression, leading to increased ROS and mesang
146 of HRP compensates less efficiently than in catalases for the energetic cost required to reorient th
150 ess response elements were identified in the catalase gene and were shown to bind ATF6 in cardiac myo
152 first assembled MGII metagenome containing a catalase gene, which might be involved in scavenging rea
154 was demonstrated by decreased expression of catalase, glutathione peroxidase 4, and glutathione synt
155 +WP diet increased the activities of hepatic catalase, glutathione peroxidase and glutathione S trans
156 The GS diet improved superoxide dismutase, catalase, glutathione peroxidase and GR activities and e
158 ondialdehyde [MDA]) and antioxidant enzymes (catalase, glutathione peroxidase, and superoxide dismuta
159 and oxidative stress (superoxide dismutase, catalase, glutathione peroxidase, lipidic and protein pe
160 pecies (ROS) scavenging machinery, including catalase, glutathione synthetase, glutathione reductase,
163 D, whereas polyethylene glycol-catalase (PEG-catalase; hydrogen peroxide scavenger) had no effect.
165 hox) or STAT3 and overexpression of PDCD4 or catalase in BEAS-2B cells markedly inhibited the arsenic
166 more, we showed CSC-mediated upregulation of catalase in exosomes from uninfected cells, with a decre
167 2 cannot be ruled out due to the presence of catalase in flour and the fast reaction of H2O2 with glu
169 on factor function, or mitochondria-targeted catalase in osteoclasts, we demonstrate this is achieved
170 rum of issues involving the function of skin catalase in particular, and the native biological antiox
173 ellular addition of the inactive versions of catalase, in contrast to cells receiving HOCl alone.
175 reaction with H2O2 Our results suggest that catalase-inactive intermediates accumulate because of of
178 subunit gp91 was significantly increased in catalase-induced MDSC as determined by quantitative PCR
179 lomerase activator AGS 499 converted the PEG-catalase-inhibitable dilation to one mediated by nitric
180 eered protein form of the antioxidant enzyme catalase-inhibited cancer stem-like cells (CSCs), and tr
181 l cell line, and addition of the competitive catalase inhibitor hydroxylamine resulted in a dose-depe
184 position-dependent oxidant-quenching role of catalase is more important than the well described H2O2-
185 The H2O2 hydrolysing activity of purified catalase is necessary in order to stabilize glucose oxid
186 We show that mitochondrial targeting of catalase is sufficient to rescue redox transients, SOCE,
188 detoxification or fight response mediated by catalase (KatA) and a dispersion or flight response medi
190 changes, including the downregulation of the catalase KatG, an activating enzyme required for isoniaz
191 , we examined the presence of genes encoding catalases (katG and katE) and proteins participating in
193 lation experiments of Ras overexpression and catalase knockout in conjunction with the literature.
194 ATHase, the GDH, a monoamine oxidase, and a catalase leads to the production of enantiopure amines.
196 ) reversed astrocyte activation and restored catalase levels to normal, without changing mitochondria
205 LADR(low/-) suppressive cells are induced by catalase-mediated depletion of hydrogen peroxide (H2O2).
206 he antioxidants superoxide dismutase (SOD2), catalase, methionine sulfoxide reductase A, and the 20S
207 more, the synthetic superoxide dismutase and catalase mimetic EUK-134 also ablated the effects of hyp
210 nfocal microscopy to confirm that the ~10 nm catalase molecules are embedded in 2 mum single-crystall
211 -concept design is demonstrated by embedding catalase molecules into uniformly sized ZIF-90 crystals
212 rotein expression by immune dot-blotting and catalase mRNA by a real-time polymerase chain reaction (
214 anthionine synthase, glutathione synthetase, catalase, Na+/H+ antiporter, etc) not found in Dg1.
215 We describe a cutaneous abscess caused by catalase-negative methicillin-susceptible Staphylococcus
221 calisation towards the cell body in cheAY2-, catalase- or aconitase-deficient bacteria or in bacteria
223 cts without CAD, whereas polyethylene glycol-catalase (PEG-catalase; hydrogen peroxide scavenger) had
224 d do not require activation by mycobacterial catalase peroxidase KatG are promising candidates for tr
225 nhanced the various antioxidant enzymes viz. catalase, peroxidase and superoxide dismutase with the e
229 Here, we demonstrate that a bifunctional catalase-peroxidase, MakatG1, in the locust-specific fun
233 and subsequent catalytic generation of O2 by catalase present in the underlying viable epidermis and
234 h loading efficiency, sustained release, and catalase preservation against proteases degradation.
235 n mCAT mice expressing mitochondria-targeted catalase prevented Sirt3 and SOD2 impairment and attenua
236 ly, mitochondrial-targeted overexpression of catalase prevented the HFD-induced ischemic limb necrosi
237 -photon microscopy revealed that anti-ICAM-1/catalase prevents the transition of microglia to an acti
238 ion measurements of katE, a gene involved in catalase production to alleviate oxidative stress, suppo
244 ins not reported to have chaperone activity: catalase, pyruvate kinase, albumin, lysozyme, alpha-lact
246 , was found to suppress DNA damage at a NQO1/catalase ratio found in healthy cells, but was clearly o
249 lene oxide synthase and the newly identified catalase-related hydroperoxide lyase and given the role
250 of the lyase expands the known reactions of catalase-related proteins and functions in Nostoc in spe
252 ovide compelling evidence that F. tularensis catalase restricts reactive oxygen species to temper mac
253 The Nrf2 inducer resveratrol, as opposed to catalase, reversed oxidative stress in lung epithelial c
254 OS) serine 1179 phosphorylation, whereas PEG-catalase scavenging of intracellular hydrogen peroxide o
255 ted expressions of both antioxidant enzymes (catalase, SOD1, and SOD2) and antiapoptotic proteins (Bc
256 orial treatment with N-acetyl-l-cysteine and catalase substantially inhibited the ROS upsurge and PIN
257 revented by the antioxidants glutathione and catalase, suggesting that HDM-induced reactive oxygen an
258 creased the transcription of ROS scavengers (catalase, superoxide dismutase 2) in HF keratinocytes.
259 tamine synthetase, alanine aminotransferase, catalase, superoxide dismutase, ornithine decarboxylase,
260 ression by release of microRNA-146a-mediated catalase suppression, where intervention within this pat
262 man chondrocytes by adenoviral expression of catalase targeted to the mitochondria (MCAT) and in cart
263 Biochemically, KatB was an efficient, robust catalase that remained active in the presence of high co
267 Furthermore, expression of an ER-adapted catalase to degrade lumenal H2O2 attenuated PRDX4-mediat
270 causative agent for these responses, as both catalase-treated and pyruvate oxidase-deficient bacteria
271 Similarly, combined N-acetyl-l-cysteine and catalase treatment also suppressed VDAC1-induced redistr
272 g the activity of superoxide dismutase-2 and catalase, two antioxidant enzymes that protect the cells
278 ion of the hydrogen peroxide-reducing enzyme catalase was dramatically reduced, which was associated
279 ineering strategy in which the OS suppressor catalase was ectopically expressed in mitochondria (mCAT
285 2, levels of oPMN superoxide dismutase 1 and catalase were decreased in severe CP, despite increased
288 ), TH2 immunity (IL4), and oxidative stress (catalase) were validated in an independent asthmatic coh
289 thione peroxidase, superoxide dismutase, and catalase, were evaluated in each of the infected, treate
292 hat mitochondrial targeted overexpression of catalase, which is established to mitigate oxidative str
293 tified here reside outside the ER, including catalase, which is known to decrease damaging reactive o
294 constructed with the aim to study the enzyme catalase, which is part of the biological antioxidative
295 e that skin contains a substantial amount of catalase, which is sufficient to detoxify H2O2 that reac
298 ery of NRF2 was more effective than SOD2 and catalase, while expression of PGC1a accelerated photorec
299 ains (katA(H56A) and katA(Y339A)) containing catalase without enzyme activity but that retain all Met
300 iomarkers (body weight, protein, chitobiase, catalase, xenobiotic metabolism, and acetylcholinesteras
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