ライフサイエンスコーパス: catalytic subunit

1 rodimer and the DNA-dependent protein kinase catalytic subunit.

2 e two domains, creating room for binding the catalytic subunit.

3 of the regulatory subunit and release of the catalytic subunit.

4 hat forms a tight complex with BSSalpha, the catalytic subunit.

5 rget of VR23 was beta2 of the 20S proteasome catalytic subunit.

6 ) inhibits holoenzyme reassociation with the catalytic subunit.

7 p110alpha and p110beta isoforms of the PI3K catalytic subunit.

8 horylation of the activation loop within the catalytic subunit.

9 with Pi3k92e, the human ortholog of the p110 catalytic subunit.

10 f a ubiquitin-associated (UBA) motif in most catalytic subunits.

11 bits the enzymatic activity of class IA PI3K catalytic subunits.

12 y subunit homodimer causes activation of the catalytic subunits.

13 ubsequent increases in glucose-6-phosphatase catalytic subunit-2 (G6PC2) levels contribute to lipotox

14 Apolipoprotein B mRNA-editing enzyme catalytic subunit 3 (APOBEC-3) enzymes are cytidine deam

15 e of the human ATP6V1A gene that encodes the catalytic subunit A of V-ATPase in GC.

16 hosphatase 2 (PP2A) holoenzyme consists of a catalytic subunit, a scaffold subunit, and a regulatory

17 athione reductase, glutamate-cysteine ligase catalytic subunit, ABCC1, peroxiredoxin 1).

18 ed with a decrease of protein kinase A (PKA) catalytic subunit alpha (Calpha) expression both at the

19 ions of the phosphoinositide-3-kinase (PI3K) catalytic subunit alpha gene (PIK3CA) are frequent in en

20 DNAJB1) to the protein kinase cAMP-activated catalytic subunit alpha gene (PRKACA) has been repeatedl

21 potential targets of miR-10a, including the catalytic subunit alpha of PI3K (PIK3CA), the central co

22 ations observed in PIK3CA, which encodes the catalytic subunit alpha of the phosphatidylinositol-4,5-

23 sphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha, PI(3)Kalpha) mutation.

24 ) is a heterotrimeric complex, composed of a catalytic subunit (alpha) and two regulatory subunits (b

25 aning of stress responses and requires a PP1 catalytic subunit and a regulatory subunit, PPP1R15A/GAD

26 Cas1 is the catalytic subunit and Cas2 substantially increases integ

27 eased PKA activity due to an unregulated PKA catalytic subunit and increased PKA type II (PKA-II) act

28 sociate with distinct surfaces of the larger catalytic subunit and influence the enzymatic properties

29 t when both the DNA-dependent protein kinase catalytic subunit and Ku accompany Artemis but not when

30 atory subunit MYPT1 bound to the phosphatase catalytic subunit and myosin.

31 SSB1 interacts with the TERT catalytic subunit and regulates its interaction with tel

32 (102) YB-1 coimmunoprecipitated with PP1beta catalytic subunit and RSK-2.

33 ed of the histone acetyltransferase 1 (Hat1) catalytic subunit and the Hat2 (rbap46) histone chaperon

34 loenzymes that contain a common scaffold and catalytic subunits and a variable regulatory subunit.

35 (PRC1) is defined by the composition of its catalytic subunits and is highly regulated by RYBP/YAF2-

36 ss response genes glutamate-cysteine ligase, catalytic subunit, and NAD(P)H dehydrogenase, quinone 1,

37 heme oxygenase-1, glutamate-cysteine ligase catalytic subunit, and NAD(P)H quinone oxidoreductase 1

38 All NATs contain at least one catalytic subunit, and some contain one or two additiona

39 f PBAF including the Swi/Snf-associated Brg1 catalytic subunit, and the other contains Baf180 but not

40 nits associate with and inhibit all class IA catalytic subunits, APDS2 mutations are expected to simi

41 tions in PIK3CD, which encodes the p110delta catalytic subunit, are capable of promoting immune defic

42 easured the protein expression of proteasome catalytic subunits as well as essential subunits from pr

43 erase (SPT) and the expression of its SPTLC3 catalytic subunit, as well as reduced ceramide synthase

44 ase in net phosphorylation of the AMPK alpha catalytic subunit at Thr-172 by augmenting phosphorylati

45 abidopsis ferredoxin : thioredoxin reductase catalytic subunit (AtFTRc), a key component of host anti

46 subunits are always in large molar excess of catalytic subunits (average approximately 17-fold).

47 we investigated the role of the 110-kDa PI3K catalytic subunit beta (p110beta) in myogenesis and meta

48 t TIR-199 covalently binds each of the three catalytic subunits (beta1, beta2, and beta5) and reveale

49 ediated by induction of the immunoproteasome catalytic subunit beta5i.

50 /polymerase and C-terminal domains (CTDs) of catalytic subunits bound to indispensable B-subunits, wh

51 Prior to signaling, PKA-R holds the kinase's catalytic subunit (C) in an inactive state by exerting a

52 t of PKA (R), unleashing the activity of the catalytic subunit (C).

53 ly later in life, and this involves PKA, its catalytic subunit Calpha, and the Wnt/beta-catenin pathw

54 We found that knockdown of these calcineurin catalytic subunits caused cardiac restriction under norm

55 re, we describe a unique role for the orphan catalytic subunit CcoN4 in colony biofilm development an

56 ined by an inhibitory phosphorylation of the catalytic subunit Cdc28 on a conserved tyrosine (Tyr(19)

57 thase-II (Chs2) and chitin synthase-III (the catalytic subunit Chs3 and its activator Chs4), respecti

58 lly regulated by TNF-induced casein kinase 2 catalytic subunit (CK2alpha') phosphorylation of nuclear

59 verexpression of CK2, particularly the alpha catalytic subunit (CK2alpha, CSNK2A1), has been implicat

60 regulatory subunits, Ckb1 and Ckb2, and two catalytic subunits, Cka1 and Cka2.

61 Ca(2+)/CaM) to relieve autoinhibition of the catalytic subunit (CNA) by its C terminus.

62 was mediated by reduced PKA activity and PKA catalytic subunit content in the cytoplasm and myofilame

63 other features of PKA signaling for reducing catalytic subunit diffusion and increasing recapture rat

64 rylation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) at the Thr2609 cluster is e

65 DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a central component of n

66 DNA-dependent protein kinase catalytic subunit (DNA-PKcs) plays a key role in mediati

67 a complex with DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) that carries out endonucleo

68 KDC encodes for DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a kinase that forms part o

69 n also involves DNA-dependent protein kinase catalytic subunit (DNA-PKcs), although the detailed regu

70 Since SAF-A, DNA-PK catalytic subunit (DNA-PKcs), and protein phosphatase 6

71 itin ligase for DNA-dependent protein kinase catalytic subunit (DNA-PKcs), can promote DNA damage-ind

72 ependent on the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), which can bind to and phos

73 ctors including DNA-dependent protein kinase catalytic subunit (DNA-PKcs), XRCC4-like factor (XLF), a

74 holoenzyme is composed of the DNA polymerase catalytic subunit E9 associated with its heterodimeric c

75 PC), containing mitotic kinase Aurora B as a catalytic subunit, ensures faithful chromosome segregati

76 on of Ku70 and DNA-dependent protein kinase, catalytic subunit, essential DNA repair proteins in the

77 Prothrombinase is composed of a catalytic subunit, factor Xa (fXa), and a regulatory sub

78 ion of Thr-210 on the activation loop of its catalytic subunit; following activation, Snf1 regulates

79 In mammals, the R1 catalytic subunit forms an active complex with either on

80 mma2, leptin (Lep), and glucose-6-phophatase catalytic subunit (G6pc) in differentiated 3T3-L1 cells

81 nase 1 (PCK1), and the glucose-6-phosphatase catalytic subunit (G6PC).

82 Variants near the calcineurin catalytic subunit gamma gene PPP3CC and the polypeptide

83 gets serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform, neurofilament light cha

84 ygenase 1 (Hmox1), glutamate-cysteine ligase catalytic subunit (Gclc) and paraoxonase 1 (PON1).

85 fering with the association of ADA2 with the catalytic subunit GCN5.

86 ated by hypoxia, and although the AMPKalpha1 catalytic subunit has been implicated in angiogenesis, l

87 ated by hypoxia, and although the AMPKalpha1 catalytic subunit has been implicated in angiogenesis, l

88 es OTULIN and CYLD, which associate with the catalytic subunit HOIP.

89 n the human telomerase reverse transcriptase catalytic subunit (hTERT) have previously been identifie

90 inhibits the binding of IKKgamma to the IKK catalytic subunits, IKK-alpha and -beta, and attenuates

91 appaB-Kinase (IKK) complex-consisting of the catalytic subunits, IKKalpha and IKKbeta, as well as the

92 1 or PKM2, the knocking down of AMPKalpha1/2 catalytic subunit in H1299 cells induced apoptosis.

93 he AMPK alpha2-subunit, the predominant AMPK catalytic subunit in the brain.

94 Vacuolar protein-sorting 34 (Vps34), the catalytic subunit in the class III PtdIns3 (phosphatidyl

95 mTOR primarily functions as a catalytic subunit in two structurally related but functi

96 plies that the retention of the -AAX in PDE6 catalytic subunits in Rce1(-/-) mice is responsible for

97 binds the telomerase reverse transcriptase (catalytic subunit) in some cell lines, raising the possi

98 s of telomerase reverse transcriptase (TERT) catalytic subunit, in particular in cancer progression,

99 PTEN) and multiple isoforms of class IA PI3K catalytic subunits, including p110alpha and p110delta, w

100 nant human PDE3A isoforms by recombinant PKA catalytic subunit increased co-immunoprecipitation with

101 muscle cells, or cell lines expressing AChE catalytic subunits, incubated with synthetic proline-ric

102 incorporates two different paralogs of each catalytic subunit into active proteasomes.

103 hibits further cycling and release of active catalytic subunits into the cytoplasm, thus resulting in

104 ase-activating Sli15/INCENP scaffold and the catalytic subunit Ipl1/Aurora B.

105 ry subunit of a deubiquitinase complex whose catalytic subunit is BAP1.

106 PP2A catalytic subunit is stabilized by G5 treatment, and its

107 nge is to understand how the activity of PKA catalytic subunits is directed in cells.

108 odes an islet-specific glucose-6-phosphatase catalytic subunit, is the most important common determin

109 dding yeast, this complex is composed of two catalytic subunits, Lac1 and Lag1, as well as an essenti

110 rough an interplay between its accessory and catalytic subunits mediated by the histone H4 tail of th

111 A is a heterodimeric complex consisting of a catalytic subunit (Naa10/ARD1) and an auxiliary subunit

112 complex I activity due to the absence of the catalytic subunit NDUFV1 (for NADH:ubiquinone oxidoreduc

113 teine desulfurase complex that consists of a catalytic subunit (NFS1), LYR protein (ISD11), and acyl

114 Five contigs encoding homologs of the catalytic subunit of alkylsuccinate synthase (assA) were

115 BRD4S directly bound BRG1, a catalytic subunit of BAF, via its bromodomain and extrat

116 that also includes SV40 large T antigen, the catalytic subunit of cellular telomerase, and oncogenic

117 binding analysis reveals that CK2alpha, the catalytic subunit of CK2, binds across RNA-polymerase-II

118 Using primary kidney cells lacking a catalytic subunit of Cn (CnAalpha(-/-) or CnAbeta(-/-)),

119 sed DNA damage and reduced expression of the catalytic subunit of DNA polymerase alpha.

120 ic mutations in REV3L, the gene encoding the catalytic subunit of DNA polymerase zeta involved in tra

121 s the expression of POLA1, which encodes the catalytic subunit of DNA polymerase-alpha.

122 ere we show that ATM is hyperactive when the catalytic subunit of DNA-dependent protein kinase (DNA-P

123 The catalytic subunit of DNA-PK (DNA-PKcs) is a vertebrate-s

124 TMDs) 4 and 5 of human presenilin 1 (PS1), a catalytic subunit of gamma-secretase.

125 Conditional gene targeting of the catalytic subunit of glutamate cysteine ligase (Gclc) bl

126 e early genes and phosphorylates INTS11, the catalytic subunit of Integrator.

127 teractions of mutant KATNB1 with KATNA1, the catalytic subunit of Katanin, and other microtubule-asso

128 We discovered a mutation in the catalytic subunit of liver glycogen phosphorylase kinase

129 7P) mutation in the gene encoding Naa10, the catalytic subunit of NatA, the major human NAT involved

130 Mutations in the catalytic subunit of phosphoinositide 3-kinase (PIK3CA)

131 have an activating mutation in p110alpha, a catalytic subunit of phosphoinositide 3-kinase.

132 tions in PIK3CA, which encodes the p110alpha catalytic subunit of phosphoinositide-3-kinase (PI3K) ar

133 We demonstrate that the p110delta catalytic subunit of PI3K acts as a downstream effector

134 mutations (activating mutations in the alpha catalytic subunit of PI3K) in human cancers.

135 c mutations in PIK3CA, the gene encoding the catalytic subunit of PI3K, PI3K inhibitors have yielded

136 ed GATA3-induced expression of the p110alpha catalytic subunit of PI3K.

137 s have identified recurrent mutations in the catalytic subunit of PKA in tumors associated with Cushi

138 Addition of the catalytic subunit of PKA increased by 566% the spontaneo

139 1 Among the DDX3 regulon, Prkaca encodes the catalytic subunit of PKA, a potential activator of Rac1

140 , whereas the active RSK1 interacts with the catalytic subunit of PKA.

141 We show that the amino-terminal tails of the catalytic subunit of Pol alpha and the Sld5 subunit of G

142 interacts with the C-terminal domain of the catalytic subunit of polalpha (p180C).

143 (enhancer of zeste homologue 2 or 1) is the catalytic subunit of polycomb repressive complex 2 (PRC2

144 rs Enhancer of zeste homologue 2 (EZH2), the catalytic subunit of Polycomb Repressive Complex 2 (PRC2

145 that enhancer of zeste homolog 2 (EZH2), the catalytic subunit of polycomb repressive complex 2 that

146 action with enhancer of zeste homolog 2, the catalytic subunit of polycomb repressive complex 2, and

147 istically, Chaer directly interacts with the catalytic subunit of polycomb repressor complex 2 (PRC2)

148 itional knockout of the alpha isoform of the catalytic subunit of PP2A (PP2ACalpha).

149 ntified PROTEIN PHOSPHATASE 2A-3 (PP2A-3), a catalytic subunit of PP2A holoenzymes, as a previously u

150 specific modification and degradation of the catalytic subunit of PP2A when bound to microtubules.

151 r SET and the phosphorylation of Y307 of the catalytic subunit of PP2A.

152 fering RNA (siRNA)-mediated knockdown of the catalytic subunit of PP6 in infected cells resulted in t

153 the stem cell population, RNF2, the dominant catalytic subunit of PRC1, activates transcription of Sa

154 Knockdown of Ezh2, the catalytic subunit of PRC2 for histone H3K27 methylation,

155 Importantly, ATM binds and activates the catalytic subunit of protein kinase A (PKAc), ribosmal S

156 in CPA with somatic mutations in either the catalytic subunit of protein kinase A (PRKACA) or the gu

157 olog, subfamily B, member 1, DNAJB1, and the catalytic subunit of protein kinase A, PRKACA.

158 ocalization and substrate specificity of the catalytic subunit of protein phosphatase 1 (PP1c) is dic

159 -localized nucleoporin MEL-28/ELYS docks the catalytic subunit of protein phosphatase 1 (PP1c) to dir

160 searched for proteins that interact with the catalytic subunit of protein phosphatase 2A (PP2Ac).

161 1 (MID1), which binds to and deactivates the catalytic subunit of protein phosphatase 2Ac, resulting

162 We identify the catalytic subunit of protein phosphatase 6 (PP6c) as the

163 39del mutations in POLR2A, which encodes the catalytic subunit of RNA polymerase II, hijack this esse

164 tify a site of ubiquitination (K1246) in the catalytic subunit of RNAPII close to the DNA entry path.

165 one deacetylases (HDACs) 1, 2 and 3 form the catalytic subunit of several large transcriptional repre

166 overexpressors of KIN10 (AKIN10/SnRK1.1), a catalytic subunit of SnRK1.

167 decrease the expression of GLT-1 and xCT (a catalytic subunit of Sxc) to determine the relative impo

168 o glutamate transporter 1 (GLT-1) and xCT (a catalytic subunit of Sxc)/Sxc upregulation in the nucleu

169 of human telomerase reverse transcriptase, a catalytic subunit of telomerase that was reversed by JNK

170 The catalytic subunit of telomerase, human telomerase revers

171 is known that the reactivation of TERT, the catalytic subunit of telomerase, is limiting for reconst

172 cade, including adenylate cyclase VI and the catalytic subunit of the cAMP-dependent protein kinase A

173 oside inhibitors of the Caf1/CNOT7 enzyme, a catalytic subunit of the Ccr4-Not deadenylase complex.

174 exes and ubiquitinates CNOT7(Caf1), the main catalytic subunit of the CCR4-NOT deadenylation machiner

175 ends on the kinase activity of Aurora B, the catalytic subunit of the chromosomal passenger complex (

176 ded mutagenesis indicates that METTL3 is the catalytic subunit of the complex, whereas METTL14 has a

177 DNA-PKcs (the catalytic subunit of the DNA-dependent kinase, encoded b

178 USP22 is the catalytic subunit of the DUB module, but two adaptor pro

179 Here, we show that Elp3, the catalytic subunit of the Elongator complex, is required

180 (2+) cluster in the C-terminal domain of the catalytic subunit of the eukaryotic B-family DNA polymer

181 Presenilin 1 (PS1), the catalytic subunit of the gamma-secretase complex, cleave

182 In addition to its known role as the catalytic subunit of the gamma-secretase complex, select

183 In addition to its known role as the catalytic subunit of the gamma-secretase complex, select

184 Inhibition of the catalytic subunit of the heterodimeric methionine S-aden

185 Here, we show that Set1, the catalytic subunit of the highly conserved Set1C/COMPASS

186 bition by gene heterozygosity of the 450-kDa catalytic subunit of the kinase (DNA-PKcs(+/-)) also pre

187 Brahma-related gene 1 (Brg1), a catalytic subunit of the mammalian SWI/SNF chromatin-rem

188 s of periplasmic nitrate reductase where the catalytic subunit of the Nap and its kinetic properties,

189 DIS3 encodes a catalytic subunit of the nuclear RNA exosome complex tha

190 ste homolog 1 (EZH1) gene, which codes for a catalytic subunit of the polycomb complex.

191 Here we show that EZH2, a catalytic subunit of the polycomb repressive complex 2 (

192 is displaced from the template to allow the catalytic subunit of the polymerase, the large protein (

193 eningiomas exhibit upregulation of EZH2, the catalytic subunit of the PRC2 complex, as well as the E2

194 telomerase reverse transcriptase (TERT), the catalytic subunit of the ribonucleoprotein complex.

195 It encodes the largest and catalytic subunit of the RNA polymerase II complex, whic

196 SMARCA4 is the catalytic subunit of the SWI/SNF chromatin-remodeling co

197 were dependent on the function of SMARCA4, a catalytic subunit of the SWI/SNF complex.

198 ic roles for Brahma-related gene 1 (Brg1), a catalytic subunit of the SWI/SNF complexes, during IPMN-

199 Snf2, the catalytic subunit of the Swi/Snf remodeling complex, has

200 ized MANTIS lncRNA interacted with BRG1, the catalytic subunit of the switch/sucrose nonfermentable c

201 versely, mutations in Tor, which encodes the catalytic subunit of the TORC1 complex, result in premat

202 C alpha (PKCalpha) interacts with TRM61, the catalytic subunit of the TRM6/61 tRNA methyltransferase.

203 Here, we report that RTCB, the catalytic subunit of the tRNA ligase complex, and its co

204 in the 3'-5' exonuclease (Exo) domain of the catalytic subunit of the viral DNA polymerase (Pol).

205 A hyperactivating mutation in the catalytic subunit of TORC1 restored LMP to the gtr1 and

206 been extensively investigated, MUS81 is the catalytic subunit of two human structure-selective endon

207 uinazolines that covalently modify a soluble catalytic subunit of V-ATPase with high potency and exqu

208 The catalytic subunits of acetylcholinesterase (AChE) are an

209 cific knockout of both the alpha1 and alpha2 catalytic subunits of AMPK (AMPK-ASKO mice) by using aP2

210 E4B are lost in hepatocytes deleted for both catalytic subunits of AMPK.

211 Interestingly, expression of the catalytic subunits of both the standard and immunoprotea

212 ehydrogenase complex subunit A and subunit B catalytic subunits of complex II, respectively.

213 Brg1 (Smarca4) and Snf2h (Smarca5) are catalytic subunits of distinct ATP-dependent chromatin r

214 of methylation on PP2Ac is conserved in the catalytic subunits of PP4 and PP6, and PP4 is also methy

215 ify 158 interactions including those between catalytic subunits of sequential enzymes and between sub

216 ional Ypk1 substrates, which pinpointed both catalytic subunits of the ceramide synthase complex.

217 Here, we demonstrate that all catalytic subunits of the CSC, known as cellulose syntha

218 e in which T cells lacked expression of both catalytic subunits of the inhibitor of kappaB kinase (IK

219 ontrols the expression of the regulatory and catalytic subunits of the phosphatidylinositol 3-kinase

220 eractions between the regulatory and the two catalytic subunits of the PKA complex in 3,726 yeast gen

221 probes for studying two of the three active catalytic subunits of the plant proteasome.

222 study the activity and role of the different catalytic subunits of the proteasome in different plant

223 We selected one of the catalytic subunits of the subfamily I, StPP2Ac2b, to dev

224 ) is a regulatory protein which inhibits the catalytic subunits of Type 2A phosphatases.

225 in this study reveals that two calcineurin A catalytic subunits (out of three) are functionally diver

226 of the phosphatidylinositol 3-kinase (PI3K) catalytic subunit (p110a), is currently in clinical tria

227 allele of the PIK3CA gene, which encodes the catalytic subunit p110alpha of PI3K (phosphatidylinosito

228 and p85beta are dispensable, the PI3-kinase catalytic subunit p110alpha requires interaction with Ra

229 Further studies showed that the catalytic subunit p110delta of class I PI3K played a rol

230 between the small GTPase Kras and the PI(3)K catalytic subunit p110delta.

231 (1) POLG codes for the 140-kilodalton (kDa) catalytic subunit, p140 and (2) POLG2 encodes the approx

232 The C terminus of the Pol alpha catalytic subunit (p180C) in complex with the B subunit

233 Activation of NOX4 requires catalytic subunit p22(phox), which is upregulated follow

234 l B-subunit (p59) in complex with CTD of the catalytic subunit (p261C).

235 nzyme in most cells, and inactivation of its catalytic subunit (P4ha1(-/-)) leads to embryonic lethal

236 Two large catalytic subunits, PDE6alpha and -beta, each contain on

237 tein expression of phosphoinositide 3-kinase catalytic subunit PI3K(p110alpha), which can promote tum

238 ing the phosphatidylinositol 3-kinase (PI3K) catalytic subunit (PIK3CA) correlates with response to n

239 activation of the phosphoinositide 3-kinase catalytic subunit, PIK3CA.

240 s of the Michaelis complex mimics of the PKA catalytic subunit (PKAc) were obtained with either pepti

241 nits (PKAR) relieves their inhibition of the catalytic subunits (PKAC).

242 se 4 (LIG4), Artemis, and DNA-protein kinase catalytic subunit (PKcs) in this process and to gain ins

243 A small C-terminal domain of the catalytic subunit Pol3 carries both iron-sulfur cluster

244 cative DNA polymerase Poldelta consists of a catalytic subunit POLD1/p125 and three regulatory subuni

245 he Pol gamma holoenzyme consists of the p140 catalytic subunit (POLG) and the p55 homodimeric accesso

246 on of the mitochondrial DNA polymerase-gamma catalytic subunit (POLG1), due to HTRA3 serine protease

247 The serine/threonine protein phosphatase-1 catalytic subunit (PP-1c) is a major protein dephosphory

248 s the alpha-isoform of protein phosphatase 1 catalytic subunit (PP1alpha) and eIF2alpha to assemble a

249 ajor phosphatase in the heart, consists of a catalytic subunit (PP1c) and a large set of regulatory (

250 loenzyme consisting of protein phosphatase-1 catalytic subunit (PP1c) and MP target subunit-1 (MYPT1)

251 ty of molecular techniques, we show that PP1 catalytic subunit (PP1c) co-localized, co-fractionated,

252 e specifically by overexpression of the PP2A catalytic subunit (PP2A-C).

253 Carboxyl methylation of the PP2A catalytic subunit (PP2Ac) C-terminal leucine is regulate

254 wn association with the cellular phosphatase catalytic subunit PP4C.

255 ived from Alzheimer's disease mapping to the catalytic subunit presenilin 1 (PS1).

256 ncode a eukaryotic-type primase comprising a catalytic subunit (PriS) and a noncatalytic subunit (Pri

257 e-dependent destruction of RPA194, the large catalytic subunit protein of Pol I holocomplex, and this

258 ility and implicate the cellular phosphatase catalytic subunit protein phosphatase 4C (PP4C) in the r

259 tory of islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP)-specific CD8(+)

260 antigen islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP206-214) reaches

261 refute the recently proposed theory that PKA catalytic subunits remain tethered to regulatory subunit

262 DNA polymerase zeta catalytic subunit REV3 is known to play an important rol

263 homologues (PCGF1 to PCGF6) with the common catalytic subunit RING1B.

264 utation in a highly conserved residue of the catalytic subunit, Rnaseh2a(G37S/G37S) (G37S), to unders

265 -rRNA processing through the activity of its catalytic subunits, Rrp6 and Rrp44.

266 rative multibranching contacts with the PP2A catalytic subunit, selective for the unmethylated tail a

267 ne backbone reported to inhibit class I PI3K catalytic subunits, several rounds of chemical syntheses

268 rough the activity of two mutually exclusive catalytic subunits, SMARCA2 and SMARCA4, which both cont

269 transcription factor (HLTF), and the SWI/SNF catalytic subunit (SNF2) translocase zinc finger ran-bin

270 Fission yeast AMPK catalytic subunit Ssp2 is phosphorylated at Thr-189 by t

271 rastically reduced upon depletion of the RSC catalytic subunit Sth1.

272 r slides and ejects nucleosomes, utilizing a catalytic subunit (Sth1) with DNA translocation activity

273 tivated potato (Solanum tuberosum), six PP2A catalytic subunits (StPP2Ac) were identified.

274 PP2A in tuberization, demonstrating that the catalytic subunit StPP2Ac2b positively modulates tuber i

275 PP2A in tuberization, demonstrating that the catalytic subunit StPP2Ac2b positively modulates tuber i

276 immunoprecipitation that OsPP2A B'', OsPP2A catalytic subunit subtype II, PSTAIRE-type CDK and OsRBR

277 The new arrangement of catalytic subunits suggests that the mechanism of ATP ge

278 To synthesize telomeric repeats, the catalytic subunit telomerase reverse transcriptase (TERT

279 dominant negative variant of the polymerase catalytic subunit that can effectively compete with wild

280 me packaging motor, is composed of one large catalytic subunit tightly associated with two DNA recogn

281 -terminase protomer is composed of one large catalytic subunit tightly associated with two DNA recogn

282 se (PI3K) is to associate with the p110alpha catalytic subunit to allow stimuli-dependent activation

283 ory subunit, facilitating the access of PP2A catalytic subunit to CK1varepsilon and its activation, w

284 gulatory subunit to allow association of the catalytic subunit to reform the holoenzyme complex.

285 BRPF1 links the MOZ catalytic subunit to the ING5 and hEaf6 subunits, thereb

286 regulatory subunits target highly conserved catalytic subunits to their sites of action.

287 r, the contributions of individual PI3K p110 catalytic subunits to these processes are not well-defin

288 its directing the myristylated N terminus of catalytic subunits toward the membrane for release and r

289 ite telomeric accumulation of the telomerase catalytic subunit, Trt1.

290 In human it consists of the catalytic subunits TSEN2 and TSEN34, as well as the non-

291 The yeast DUBm comprises a catalytic subunit, Ubp8, and three additional subunits,

292 esses downstream of PKA, we deleted both PKA catalytic subunits using CRISPR-Cas9, followed by a "mul

293 PI3KC3-C1 consists of the lipid kinase catalytic subunit VPS34, the VPS15 scaffold, and the reg

294 F2 enhances the lipid kinase activity of the catalytic subunit, VPS34, by roughly 10-fold.

295 phate-activated protein kinase (AMPK) alpha1-catalytic subunit, which governs cell-autonomous adaptat

296 e decreased expression of DNA-protein kinase catalytic subunit, which we have previously identified a

297 REV3L comprises the catalytic subunit, while REV7 (MAD2L2) is considered an

298 ors ARTEMIS and DNA-dependent protein kinase catalytic subunit, with defects in the hairpin opening s

299 elucidate a parallel organization of the two catalytic subunits, with juxtaposed alpha-helical segmen

300 taneous measurement of the activity of these catalytic subunits would assist in the discovery of new