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1 of sepsis-induced indirect pulmonary injury (cecal ligation and puncture).
2 ubjected to polymicrobial sepsis (induced by cecal ligation and puncture).
3 l after endotoxemia or polymicrobial sepsis (cecal ligation and puncture).
4 induced ALI) and indirect ALI (systemic LPS, cecal ligation and puncture).
5 xic shock and polymicrobial sepsis following cecal ligation and puncture.
6 or water for 12 weeks and then subjected to cecal ligation and puncture.
7 nergic activity decreased six-fold following cecal ligation and puncture.
8 ect on cytokine/chemokine serum levels after cecal ligation and puncture.
9 Male C57Bl6 mice were made septic using cecal ligation and puncture.
10 pe mice were subjected to sham laparotomy or cecal ligation and puncture.
11 d much higher mortality after endotoxemia or cecal ligation and puncture.
12 ls of intraperitoneal lipopolysaccharide and cecal ligation and puncture.
13 and mortality after intraperitoneal LPS and cecal ligation and puncture.
14 and mortality after intraperitoneal LPS and cecal ligation and puncture.
15 in increased survival, but not after 20 h of cecal ligation and puncture.
16 Sepsis was induced by cecal ligation and puncture.
17 se mortality in a model of sepsis induced by cecal ligation and puncture.
18 following polymicrobial sepsis initiated by cecal ligation and puncture.
19 D73 knockout (KO) and wild type (WT) mice to cecal ligation and puncture.
20 ng acute intra-abdominal infection caused by cecal ligation and puncture.
21 aride (LPS) or a polymicrobial infection via cecal ligation and puncture.
22 tion and polymicrobial peritonitis caused by cecal ligation and puncture.
23 the peritoneal cavity increased by 774% with cecal ligation and puncture.
24 subjected to bilateral nephrectomy and sham cecal ligation and puncture.
25 p-1 also sensitized mice to sepsis caused by cecal ligation and puncture.
26 bacterial peritonitis and sepsis induced by cecal ligation and puncture.
27 rat model of septic peritonitis, induced by cecal ligation and puncture.
28 esistance to polymicrobial sepsis induced by cecal ligation and puncture.
29 type and C3- or C5-deficient mice induced by cecal ligation and puncture.
30 al infection were assessed in mice following cecal ligation and puncture.
31 e production and a lower survival rate after cecal ligation and puncture.
32 significantly decreased mortality following cecal ligation and puncture.
33 hat cyclophilin increased in abundance after cecal ligation and puncture.
34 t not in TNFR2(-/-) mice following sublethal cecal ligation and puncture.
35 e had CMV reactivation beginning 2 wks after cecal ligation and puncture.
36 thality from polymicrobial sepsis induced by cecal ligation and puncture.
37 uction of polymicrobial, abdominal sepsis by cecal ligation and puncture.
38 a rat model of circulatory shock induced by cecal ligation and puncture.
39 ovir (10 mg/kg/day subcutaneously) following cecal ligation and puncture.
40 ibrosis compared with MCMV- mice 3 wks after cecal ligation and puncture.
41 ansia species and the survival benefit after cecal ligation and puncture.
42 ls are a critical factor in sepsis following cecal ligation and puncture.
43 Polymicrobial sepsis was induced by cecal ligation and puncture.
44 re not a critical factor in sepsis following cecal ligation and puncture.
45 inflammation in septic mice challenged with cecal ligation and puncture.
46 mice, ranging from 339 to 529 minutes after cecal ligation and puncture.
47 re euthanized at 18 hours after induction of cecal ligation and puncture.
48 himeric mice were generated and subjected to cecal ligation and puncture.
49 n wild-type mice when subjected to sepsis by cecal ligation and puncture.
50 Sepsis was induced by cecal ligation and puncture.
51 and severe polymicrobial sepsis produced by cecal ligation and puncture.
52 hock and to polymicrobial septic shock after cecal ligation and puncture.
53 psis-intra-peritoneal lipopolysaccharide and cecal ligation and puncture.
54 of mice with polymicrobial sepsis induced by cecal ligation and puncture.
55 as induced in 10-wk-old male C57BL/6 mice by cecal ligation and puncture.
58 terial infection by Staphylococcus aureus or cecal ligation and puncture also induces HSPC expansion,
60 after intraperitoneal lipopolysaccharide and cecal ligation and puncture, also resulted in decreased
61 after intraperitoneal lipopolysaccharide and cecal ligation and puncture and decreased vascular leak,
62 ered exaggerated lethality when subjected to cecal ligation and puncture and exhibited severe lung in
64 Procedures included induction of sepsis by cecal ligation and puncture and measurement of heart fun
65 Finally, IL-15 increased survival in both cecal ligation and puncture and P. aeruginosa pneumonia.
66 ues progressively increased in animals after cecal ligation and puncture and terminated in death.
67 ate groups of nontransplanted mice underwent cecal ligation and puncture and were euthanized 24 hours
68 saline (7.5% NaCl, 4 mL/kg) before or after cecal ligation and puncture, and acute lung injury and m
70 e bone marrow during late sepsis, induced by cecal ligation and puncture, and demonstrated that they
71 cytokines were increased in serum following cecal ligation and puncture, and interleukin 10 and mono
72 protein-1 and interleukin-6 levels following cecal ligation and puncture, and peritoneal macrophage i
73 nt mice exhibited enhanced susceptibility to cecal ligation and puncture- and LPS-induced sepsis, whi
74 sham control + trametinib (1 mg/kg, IP); 3) cecal ligation and puncture; and 4) cecal ligation and p
75 When compared with sham-operated animals, cecal ligation and puncture animals developed hypotensio
76 creased greatly in mice after endotoxemia or cecal ligation and puncture as compared with sham mice.
77 PC (APC), was significantly increased after cecal ligation and puncture as well as in the microvascu
78 applied 2 stringent animal models of sepsis: cecal ligation and puncture as well as intraperitoneal i
79 ided beneficial effects to rats subjected to cecal ligation and puncture, as shown by reduced systemi
80 nal-regulated kinase signaling 6 hours after cecal ligation and puncture attenuated increases in circ
81 l signs were repeated at 25 or 49 hours post-cecal ligation and puncture, blood was collected, animal
82 severity of illness and improved survival in cecal ligation and puncture, both as a pretreatment and
83 spleen were significantly elevated following cecal ligation and puncture but were reduced by the abse
84 d pituitary hormones increased 24 hours post-cecal ligation and puncture but were significantly lower
85 We used a mouse model of sepsis based on cecal ligation and puncture, but with fluid and antibiot
87 ore, we demonstrated that surgical stress or cecal ligation and puncture caused a decrease in CRAMP e
89 In mice exposed to septic stress induced by cecal ligation and puncture, Chk2 levels in the intestin
92 osphorylation by 31 +/- 11% following murine cecal ligation and puncture (CLP) at 8 h and 34 +/- 9% f
93 tation in gut epithelial apoptosis following cecal ligation and puncture (CLP) compared to septic WT
95 ally relevant two-hit model of sepsis, i.e., cecal ligation and puncture (CLP) followed by the induct
98 utophagy are up-regulated in the liver after cecal ligation and puncture (CLP) in C57BL/6 mice or in
103 to induce sepsis-induced mortality following cecal ligation and puncture (CLP) in the severely immuno
104 Akt in CMs exposed to C5a in vitro and after cecal ligation and puncture (CLP) in vivo In both cases,
106 compared with vehicle control in the murine cecal ligation and puncture (CLP) model and in the pneum
108 eveloped, the most frequently used being the cecal ligation and puncture (CLP) model in rodents.
109 ated immune and inflammatory mechanisms in a cecal ligation and puncture (CLP) model of sepsis over 2
117 r2 in inflammation following endotoxemia and cecal ligation and puncture (CLP) models of sepsis.
119 of the development of AKI during sepsis, the cecal ligation and puncture (CLP) murine model of sepsis
120 ting that mast cells can promote survival in cecal ligation and puncture (CLP) of moderate severity.
123 saccharide-induced endotoxemia model and the cecal ligation and puncture (CLP) peritonitis model.
124 We developed a biotelemetry-based model of cecal ligation and puncture (CLP) that standardizes the
125 knockout (LOX-1(-/-)) mice were subjected to cecal ligation and puncture (CLP) to induce sepsis.
128 rosis factor (TNF)-induced lethal shock, and cecal ligation and puncture (CLP) were performed in gene
132 ons of NT are increased in mice after severe cecal ligation and puncture (CLP), a model of sepsis, an
133 ee RNA was significantly increased following cecal ligation and puncture (CLP), an animal model of po
134 sified during experimental sepsis induced by cecal ligation and puncture (CLP), as reflected by risin
135 llowed by treatment with AB103; or underwent cecal ligation and puncture (CLP), followed by treatment
136 of a classic model of polymicrobial sepsis, cecal ligation and puncture (CLP), in C57BL/6J-mMCP-4-de
137 the model of polymicrobial sepsis induced by cecal ligation and puncture (CLP), we investigated the r
138 ry responses, and organ injury in a model of cecal ligation and puncture (CLP), with or without antib
139 this, we used our published murine model of cecal ligation and puncture (CLP)-induced polymicrobial
140 baric oxygen (HBO2) therapy is protective in cecal ligation and puncture (CLP)-induced sepsis and if
141 e report that hepatic SR-BI protects against cecal ligation and puncture (CLP)-induced sepsis as show
142 segmented filamentous bacterium (SFB) after cecal ligation and puncture (CLP)-induced sepsis using m
144 r CD36 are protected from antibiotic-treated cecal ligation and puncture (CLP)-induced sepsis, with g
147 psis, severe sepsis, and septic shock and in cecal ligation and puncture (CLP)-induced septic mice.
148 bitor, improves survival in a mouse model of cecal ligation and puncture (CLP)-induced septic shock.
170 t stress during bacterial sepsis {lsqb;i.e., cecal ligation and puncture (CLP){rsqb; resulting in inc
173 ecrease organ damage while improving septic (cecal ligation and puncture, CLP) mouse survival, little
177 ally relevant model of polymicrobial sepsis (cecal ligation and puncture), DJ-1(-/-) mice had improve
178 scopy, collagen elastic modulus was lower in cecal ligation and puncture-exposed rats at 24 hours (1.
179 femoral neck were significantly reduced for cecal ligation and puncture-exposed rodents at 24 hours
180 dulus was similar at 24 hours but reduced in cecal ligation and puncture-exposed rodents at 96 hours
184 Serial blood specimens were obtained after cecal ligation and puncture for serum creatinine, interl
185 Lung tissue homogenates were evaluated after cecal ligation and puncture for tumor necrosis factor-al
188 nstrated a loss of DTH for the 7 d following cecal ligation and puncture; however, the immune respons
192 g host defense to polymicrobial sepsis after cecal ligation and puncture in gene-deficient mice.
194 alloproteinase-8 improves survival following cecal ligation and puncture in mice, making it a potenti
195 pothesis, we induced polymicrobial sepsis by cecal ligation and puncture in wild-type (WT) mice and t
196 Model of polymicrobial sepsis induced by cecal ligation and puncture in wild-type and toll-like r
197 er intraperitoneal lipopolysaccharide and/or cecal ligation and puncture included mortality, vascular
198 ns, serial injections of apoE for 24 h after cecal ligation and puncture increased the frequency, cel
199 l of the acute inflammatory response in CLP (cecal ligation and puncture)-induced sepsis in rats.
200 tive to FXI-expressing wild-type mice during cecal ligation and puncture-induced acute peritonitis/se
202 lved in the regulation of immune function in cecal ligation and puncture-induced murine polymicrobial
206 bacterial dissemination, and inflammation in cecal ligation and puncture-induced polymicrobial sepsis
207 ous Ag-specific CD4 T cell populations after cecal ligation and puncture-induced sepsis and analyzed
208 the role of each receptor in the setting of cecal ligation and puncture-induced sepsis by using anti
209 jury develops in mice predicted to die after cecal ligation and puncture-induced sepsis compared with
211 ation of iCRT3 to C57BL/6 mice, subjected to cecal ligation and puncture-induced sepsis, decreases th
212 t of mice, initiated 24 h after the onset of cecal ligation and puncture-induced sepsis, significantl
215 Toll-like receptor 9-deficient mice with cecal ligation and puncture-induced severe sepsis did no
216 om toll-like receptor 9--deficient mice with cecal ligation and puncture-induced severe sepsis expres
218 signal-regulated kinase blockade attenuated cecal ligation and puncture-mediated up-regulation of cy
222 d 85% (p = 0.007), whereas in the jejunum of cecal ligation and puncture mice sodium-dependent glucos
223 cterial titers compared with vehicle-treated cecal ligation and puncture mice that succumbed at 48 h.
228 quences of PC suppression on the kidney in a cecal ligation and puncture model of polymicrobial sepsi
229 st (CJ-12,255) would improve survival in the cecal ligation and puncture model of sepsis in adult fem
231 ast cell-specific IL-6-deficient mice to the cecal ligation and puncture model of septic peritonitis,
232 ation and generate a physiology-based murine cecal ligation and puncture model that is more similar t
240 reduced mortality in lipopolysaccharide and cecal-ligation-and-puncture models of sepsis, but not in
241 of vehicle, endotoxin preconditioning in the cecal ligation and puncture mouse model of sepsis led to
245 ine production during septic shock caused by cecal ligation and puncture or endotoxin-induced shock.
246 was induced in Mye-K/O and wild-type mice by cecal ligation and puncture or intraperitoneal injection
247 ered both before and after sepsis induction (cecal ligation and puncture or lipopolysaccharides) intr
251 P70(-/-) mice than aged WT mice subjected to cecal ligation and puncture (p = 0.01), suggesting HSP70
254 bial septic peritonitis induced by sublethal cecal ligation and puncture, properdin-deficient mice ap
255 Young HSP70(-/-) and WT mice subjected to cecal ligation and puncture, Pseudomonas aeruginosa pneu
256 e before or shortly after inducing sepsis by cecal ligation and puncture reduced mortality and improv
257 r diet demonstrated increased survival after cecal ligation and puncture relative to mice receiving l
262 he initiation of sepsis improved survival in cecal ligation and puncture sepsis (neurokinin-1 recepto
266 morrhagic shock followed 24 hours after with cecal ligation and puncture-septic challenge) and compar
268 id bodies (d7EBs) injected i.v. 1 hour after cecal ligation and puncture significantly reduced lung i
269 ofol on LTB4 production in vivo and in vitro Cecal ligation and puncture surgery was performed in mic
272 ary granulomas induced by S. mansoni eggs in cecal ligation and puncture survivors were significantly
273 ld for acute physiologic deterioration after cecal ligation and puncture that has adequate face and c
276 (1 x 10, intravenously) or were subjected to cecal ligation and puncture to induce polymicrobial seps
277 de to induce lethal endotoxemia or underwent cecal ligation and puncture to induce polymicrobial seps
281 We compared liver proteins from 6-hr post-cecal ligation and puncture to sham-operated mice ("earl
282 optive transfer experiments were followed by cecal ligation and puncture to test the hypothesis that
284 erapy significantly improved the survival in cecal ligation and puncture-treated scavenger receptor B
285 provides effective protection 18 hours post cecal ligation and puncture; using adrenal-specific scav
288 livers, and spleens harvested 28 hours after cecal ligation and puncture was hybridized to mouse expr
289 n inflammatory gene expression at 20 h after cecal ligation and puncture was not due to resolution of
291 pe mice treated with hypertonic saline after cecal ligation and puncture was significantly greater th
296 ment also exacerbated septic shock caused by cecal ligation and puncture when given after the onset o
297 vivors of severe experimental sepsis (murine cecal ligation and puncture), which were subsequently ch
299 rated mice ("early proteins") and 24-hr post-cecal ligation and puncture with 6-hr post-cecal ligatio
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