ライフサイエンスコーパス: cell

1 cells most closely resemble: the endothelial cell.

2 ser light to nanoparticle to fluid medium to cell.

3 he regulation of mechanotransduction by hair cells.

4 stimulation with aminobisphosphonate-treated cells.

5 s is the migration and invasion of malignant cells.

6 sed in Escherichia coli BL21(lambdaDE3)pLysS cells.

7 just 1 min of direct CAP treatment on these cells.

8 shape data for single Caulobacter crescentus cells.

9 ion of which is often dysregulated in cancer cells.

10 ls compared to 5-fluorouracil (5-FU) treated cells.

11 pic consequences in sudemycin-treated mutant cells.

12 asses of single suspended cells and adherent cells.

13 tive (MS) channels on the top surface of the cells.

14 and neuronal properties of lamprey pretectal cells.

15 ctures to affect RNA-protein interactions in cells.

16 oter activity was measured in Huh7 and HepG2 cells.

17 que subset of innate-like CD1d-independent T cells.

18 epitopes for gluten-specific CD4-positive T cells.

19 TG3 is upregulated in stressed lactate-grown cells.

20 orylation and inhibited growth of MCF7-Y537S cells.

21 opodial maturation in invasive breast cancer cells.

22 n of this variation between molecules across cells.

23 accumulation of protein deposits in neuronal cells.

24 ) are critical for efficient HR in mammalian cells.

25 moting the recruitment of other inflammatory cells.

26 co-localizes with R-loops in cultured human cells.

27 478G, induced cell death selectively in 661W cells.

28 e number of iNKT cells, particularly of NKT1 cells.

29 promote DNA synthesis in wild-type fat body cells.

30 cription factor-DNA binding in neuroblastoma cells.

31 ched to the basolateral membrane of the hair cells.

32 During skin wound healing, CD26-positive cells accumulated over time and persisted in forming hyp

33 In cells, actin dynamics are regulated by kinases, such as

34 mulates the CD27 pathway, which results in T-cell activation and antitumor activity in tumor models.

35 Immune cell activation stimulates neuronal circuits that regula

36 der flow: PD1n-3 DPA and RvD5n-3 DPA reduced cell adhesion onto TNF-alpha-activated human endothelial

37 e inflammatory potential of peripheral blood cells after lunch.Compared with 3 meals/d, meal skipping

38 ible to track the masses of single suspended cells and adherent cells.

39 processes including the interactions between cells and biointerfaces, both natural and synthetic.

40 l GFP reconstitution experiments that Kenyon cells and dopamine neurons from axoaxonic reciprocal syn

41 ry interventions to rejuvenate aged/diseased cells and improve their regenerative capacities.

42 occurs through both hypertrophy of existing cells and increased differentiation of adipocyte precurs

43 AMTS7 expression in human aortic endothelial cells and lymphoblastoid cell lines.

44 the structure, energetics, and signaling of cells and organisms.

45 re, we first demonstrated that breast cancer cells and pancreatic adenocarcinoma cells generated micr

46 ed" DCs stimulated the activation of naive T cells and polarized a subset of these cells into CD4+CD2

47 had slower replication in mammalian neuronal cells and reduced virulence in 2-day-old mice.

48 in the development and activation of immune cells and their roles in immune-related diseases.

49 blood revealed Vwf expression in endothelial cells and thrombocytes.

50 Absolute counts and % of CD4+ T cells and Treg cells (CD4 + CD25 + FOXP3 + CD127dim/-) w

51 -independent activation of Vgamma9Vdelta2 T cells and, importantly, strongly reduced the production

52 that IFN-gamma induces CD70 expression in T cells, and CD70 limits T cell expansion via a regulatory

53 , reduced T-bet expression by natural killer cells, and expansion of blood monocytes with less proinf

54 silica is non-cytotoxic to J774.2 macrophage cells, and supports cell proliferation and growth.

55 w LMP1 expression is regulated in epithelial cells, and there are conflicting reports about whether i

56 ptor antibody (AT1R-Ab) and anti-endothelial cell antibody (AECA).

57 mechanism that involves caspase-dependent T cell apoptosis and upregulation of inhibitory immune che

58 r laboratory previously determined that mast cells are activated via a non-FcepsilonRI mediated respo

59 During postnatal nephrogenesis, Troy(+) cells are present in the cortex and papilla and display

60 copy (CLSM) showed that the number of fungal cells attached to the modified PMMA resin was considerab

61 gc1a(f/+)Alb-cre(+/0) mice of each sex, in a cell-autonomous manner, but was greater in livers from t

62 uxin effector ARF5/MONOPTEROS (MP) acts both cell-autonomously and noncell-autonomously to control em

63 In vitro and cell-based assays revealed that the CNAbeta1-containing

64 ies on cells via variable-length tethers for cell-based sandwich ELISA, therefore, provides a sensiti

65 sly growing mouse incisor as a model of stem cell-based tissue renewal, we found that the transcripti

66 How these different aspects of cell behavior are coordinated through a single receptor

67 Genetic and cell biological studies over almost 2 decades have revea

68 t less is known about these basic aspects of cell biology in early-diverging Apicomplexan parasites,

69 tion about different biological processes in cell biology studies.

70 portant for our mechanistic understanding of cell biology.

71 laque composition by inducing an endothelial cell (BmxCreER(T2)-driven)-specific or smooth muscle cel

72 e exception of the unique presence of RFRP-3 cell bodies in the arcuate nucleus (Arc).

73 sive changes in distribution of mRNAs in the cell body and axon compartments of peripheral sensory ne

74 Snord116p-/m+ mice the reduction in neuronal cell body size was associated with decreased neuronal nu

75 is crucial for the induction of IL-13(+) Th2 cells, but it also participates in the induction of IL-1

76 t shorter telomere length compared to normal cells, but it is not fully understood how WRN deficiency

77 thymic negative selection of autoreactive T cells by promoting the ectopic expression of tissue-spec

78 hat extent TRAIL/TRAIL-R signaling in cancer cells can affect the immune microenvironment.

79 he inhibitory microenvironment and how CAR T cells can be further engineered to maintain efficacy.

80 Here, we show that lamin A/C expressing cells can form an actin cap to resist nuclear deformatio

81 Recent studies suggest that T reg cells can participate in tissue repair in a manner separ

82 iction of local tumor recurrence after renal cell carcinoma ablation.

83 a elongation in auditory and vestibular hair cells, causing deafness and balance defects.

84 solute counts and % of CD4+ T cells and Treg cells (CD4 + CD25 + FOXP3 + CD127dim/-) were evaluated u

85 n, proliferation and differentiation of stem cell, cell survival/death, and cellular metabolism under

86 e treatment of B cell neoplasms, including B cell chronic lymphocytic leukemia (B-CLL).

87 findings add to a growing list of potential cell/circuit underpinnings that may underlie cognitive i

88 d resulted in more compactly clustered tumor-cell colonies in coculture with PC3 cells, which might b

89 , Bcl-2 and p53) in these NPs-treated cancer cells compared to 5-fluorouracil (5-FU) treated cells.

90 In vitro studies demonstrated that senescent-cell conditioned medium impaired osteoblast mineralizati

91 n be carried out by simple fine filtering of cell-conditioned medium prior to a non-NTA-determined (i

92 bohydrates over time, induced by endothelial cell contact.

93 essed, while the overall current through the cell, correlating with the water splitting process, is e

94 Induced pluripotent stem cells could potentially help to elucidate the complex me

95 , hRETNTg(+)Tlr4(-/-) mice, and human immune cell culture, we demonstrate that hRetn binds the LPS re

96 We recapitulated these results in cell cultures.

97 Here, we investigate size control and the cell cycle dependence of bacterial growth using multigen

98 l outcomes have been attributed to increased cell cycle progression and the development of genomic in

99 Cell cycle progression in mammals is strictly controlled

100 Ps) from categories including metabolism and cell cycle, as well as RNA- and protein-modifying enzyme

101 s are necessary for kinetochore assembly and cell-cycle progression.

102 lls treated or untreated with androgen after cell-cycle synchronization.

103 The mechanics of DNA replication and cell cycling are well-characterized in model organisms,

104 interaction motifs (RHIM) play a key role in cell death and inflammatory signalling(1-3).

105 re able to induce efficient apoptotic cancer cell death both in vitro and in vivo through tumor-speci

106 sclerosis-associated mutant, E478G, induced cell death selectively in 661W cells.

107 bited increased susceptibility and apoptotic cell death with oxidative stress.

108 mparative proteome profiling regarding other cells demonstrated cell-type-specific synthesis of, amon

109 typical of most tissues, we find that cancer cells depend on high levels of the iron-sulfur cluster b

110 Previously, we found that in cancer cells derived from pancreatic ductal adenocarcinoma (PDA

111 on was abolished in the mutated 231 G521R ER cells despite appropriate receptor protein expression an

112 Before birth, B cells develop in the fetal liver (FL).

113 de novo mutations occurred during early germ cell development.

114 Furthermore, T-cell diapedesis became equivalent between control and EV

115 The CD20-positive cells did not display the typical B cell morphology, hav

116 -dependent nuclear IYO accumulation triggers cell differentiation in Arabidopsis.

117 er ischemia, little is known about whether T cells directly impact cardiac fibroblasts (CFBs) to prom

118 ration of the mouse inner ear, cochlear hair cells display at least two types of mechanically gated i

119 dynamics of the bacterial outer membrane as cells divide.

120 RSF transiently after eFSE prevented granule cell dysmaturation, restored a functional balance of gam

121 To examine its role in endothelial cell (EC) biology, we generated mice with catalytic inac

122 s of SOX5/6/21 in human primary glioblastoma cells enabled expression of CDK inhibitors and decreased

123 isease, chronic immune activation leads to T-cell exhaustion.

124 Our results demonstrate that E6-expressing cells exhibit previously unappreciated mitotic defects t

125 WS cells exhibit shorter telomere length compared to normal

126 Accordingly, ROS-high NKT cells exhibited increased susceptibility and apoptotic c

127 D70 expression in T cells, and CD70 limits T cell expansion via a regulatory T cell-independent mecha

128 e mislocalization of RAD51 away from DSBs in cells expressing HPV E6 and E7 hinders HR through a dist

129 stone demethylases that both regulate normal cell fates during development and contribute to the epig

130 and covalent decoration of intimin for live cell fluorescent imaging of the dynamics of the bacteria

131 bing fibers to innervate cerebellar Purkinje cells for the control of motor learning and timing.

132 t cancer cells and pancreatic adenocarcinoma cells generated micromolar level H2O2 during just 1 min

133 that knockdown of Hop in the germ line nurse cells (GLKD) of Drosophila ovaries leads to activation o

134 In nutrient-rich fat cells, GRASP clusters in close proximity to the apical s

135 of bacterial growth using multigenerational cell growth and shape data for single Caulobacter cresce

136 and highlight the importance of postmitotic cell growth in gut epithelial repair.

137 sm underlying the effect of ILT3.Fc on tumor cell growth involves inhibition of the p70S6K signaling

138 elf-renewing, highly tumorigenic glioma stem cells (GSCs), which contributes to tumor initiation and

139 tic modification of human cardiac progenitor cells (hCPCs) are necessary interventions to rejuvenate

140 fferentiation pathways in autoreactive CD4 T cells, highlighting its potential as a therapeutic targe

141 yocardial delivery of human mesenchymal stem cells (hMSCs) is an emerging therapy for treating the fa

142 In HEK293 cells, hyperglycaemia significantly enhanced [(3) H]ryan

143 the biogenesis of master miRNAs crucial for cell identity by enhancing both transcription and Drosha

144 The potential protective role of B cells in controlling cCMV-related disease and the clinic

145 ratinocytes and their interplay with myeloid cells in dengue.

146 ethod for characterizing visually identified cells in intact neural circuits, but it requires skill t

147 espite emerging data indicating a role for T cells in profibrotic cardiac repair and healing after is

148 IV-1 can infect kidney transplant epithelial cells in the absence of detectable viremia.

149 These effects can be recovered by culturing cells in the presence of a ROS quencher or in an anaerob

150 Macrophages are prominent immune cells in the tumor microenvironment that exert potent ef

151 nd biointerfacing activities of natural stem cells in therapeutic cardiac regeneration.

152 ions to understanding the behaviour of these cells in vivo.

153 s with orthotopically injected breast cancer cells in wild-type and RAGE-knockout C57BL6 mice.

154 0 limits T cell expansion via a regulatory T cell-independent mechanism that involves caspase-depende

155 Analysis of detergent-solubilized Hrd1.KI cells indicates that the composition and stoichiometry o

156 Invasive cancer cells interact with the surrounding extracellular matrix

157 dings suggest that airway smooth muscle/mast cell interactions contribute to asthma severity by trans

158 le to bind to cell membranes, thus promoting cell internalization by active pathways, attachment of c

159 and chemotherapy induce DNA damage to drive cells into apoptosis or senescence as outcomes of the DN

160 aive T cells and polarized a subset of these cells into CD4+CD25+FoxP3+ regulatory T cells (Tregs).

161 ation-mediated LDHA activity promotes cancer cell invasion and anoikis resistance through redox homeo

162 anoikis induction and resulted in attenuated cell invasion and elevated reactive oxygen species, wher

163 Basophils are important effector cells involved in the pathogenesis of inflammatory skin

164 The metabolic phenotype of a cancer cell is determined by its genetic makeup and microenviro

165 hen a substantial proportion of mature blood cells is derived from a single dominant hematopoietic st

166 their presence and location in proteins and cells is important for understanding biological function

167 eliminating confinement errors in bacterial cells is to analyze molecule displacements only along th

168 rphology, having in general a more dendritic cell-like appearance.

169 The Cell Line Ontology (CLO) is an OBO community-based ontol

170 We found significant, coherent and non-cell line specific changes in fatty acids, glycerophosph

171 ed from a single dominant hematopoietic stem cell lineage.

172 gy that contains information of immortalized cell lines and relevant experimental components.

173 y driven by experimental variables including cell lines to organize and describe the diverse experime

174 For 95 MHC homozygous cell lines we assembled, de novo, a set of high-fidelity

175 mphocytic leukaemia and mantle cell lymphoma cell lines, and patients treated with idelalisib, but no

176 ibroblast), and RAW 264.7 (mouse macrophage) cell lines.

177 on was observed in MCC tumor tissues and MCC cell lines.

178 aortic endothelial cells and lymphoblastoid cell lines.

179 ed and 344 EFO unique immortalized permanent cell lines.

180 cular lymphoma (FL; n = 29), diffuse large B-cell lymphoma (DLBCL; n = 34), DLBCL arising from chroni

181 Results NHL subtypes included mantle cell lymphoma (MCL; n = 28), follicular lymphoma (FL; n

182 man chronic lymphocytic leukaemia and mantle cell lymphoma cell lines, and patients treated with idel

183 Cavin-2 plays a critical role in endothelial cell maintenance and function by regulating eNOS activit

184 roportion of cardiomyocytes many days before cells manifest the differentiated phenotype.

185 in the spontaneous synaptic input in mitral cells (MCs) separated up to 220 mum (300 mum with elevat

186 ach for systematic in vivo investigations of cell membrane structure.

187 l fusion proteins (F) insert into the target cell membrane, and form a transient intermediate that pu

188 To fully mimic the complexity of cell membranes and optimize the efficiency of delivery v

189 nsient intermediate that pulls the viral and cell membranes together as two heptad-repeat regions ref

190 etrating peptides (CPPs) are able to bind to cell membranes, thus promoting cell internalization by a

191 ions that mimic both bacterial and mammalian cell membranes.

192 his occurs through alteration of endothelial cell metabolism.

193 Microbial fuel cells (MFCs) are novel bio-electrochemical device for sp

194 To test the non-tumor cell microenvironment role of RAGE, we performed syngene

195 significantly decreased IL-6-mediated tumor cell migration, tumorsphere formation and ALDH-positive

196 in a target concentration range (10(2) 10(6)cells/mL) was 4.55x10(-2)muA per concentration decade, w

197 e, with the lowest detection limit of 1x10(2)cells/mL.

198 yping technology to create scarless isogenic cell models of cancer variants in 1 month.

199 positive cells did not display the typical B cell morphology, having in general a more dendritic cell

200 ine of differentiation that these neoplastic cells most closely resemble: the endothelial cell.

201 protein is necessary for TGF-beta1-dependent cell motility.

202 Remarkably, HUVEC cells naturally migrated in the ECM scaffold and spontan

203 allmark anti-CD20 mAb for the treatment of B cell neoplasms, including B cell chronic lymphocytic leu

204 hancers in DIPG provides insights toward the cell of origin, highlighting oligodendroglial lineage ge

205 This review focuses on the epithelial stem cells of skin, where they come from, where they reside,

206 NT The roles of microglia, the phagocytosing cells of the CNS, and invading macrophages in degenerati

207 The impact of dentate mossy cells on hippocampal activity remained uncertain despite

208 of extracellular release by infected CD4+ T cells on protein quality control and autophagy in cardio

209 Cell or animal models that accurately reflect the pathol

210 ation and large-scale proteomics analysis of cell or tissue lysate for enhanced proteome coverage, pa

211 unchecked expansion of invariant NKT (iNKT) cells or a unique subset of innate-like CD1d-independent

212 Very little is known about how archaeal cells orchestrate transcription on a systems level.

213 in a severe reduction in the number of iNKT cells, particularly of NKT1 cells.

214 f interleukin 23 (IL23) and T-helper (Th) 17 cell pathway molecules are increased in inflamed intesti

215 wn about the biology of amyloidogenic plasma cells (PCs).

216 Although cationic cell-penetrating peptides (CPPs) are able to bind to cel

217 epatic core samples to 50 x 10(6) autologous cells per pig.

218 ection method, phenotype/genotype (B cell, T cell, Philadelphia chromosome), and EFS and OS.

219 here formation and ALDH-positive cancer stem cell population, in vitro.

220 counter premature death of a virus-infected cell, poxviruses use a range of different molecular stra

221 shown to be involved in the regulation of T cell proliferation and function.

222 xic to J774.2 macrophage cells, and supports cell proliferation and growth.

223 ion, and delineated the relationship between cell proliferation and iCM induction.

224 YAP and TAZ are required both to maintain TA cell proliferation and to inhibit differentiation.

225 activates a second ARK, Ssp2/AMPKalpha, for cell proliferation in low environmental glucose.

226 Host cell proteins (HCP) are a major class of impurities deri

227 c form of the toxin, suggesting that human B cells recognize epitopes on the dimerized form of LukAB

228 auma, including induction of Th17-type CD4 T cells, reduced T-bet expression by natural killer cells,

229 ed that intrahepatically differentiated Treg cells relocated to the inflamed aorta in atherosclerosis

230 e level, with an impact on surrounding brain cells, remains unknown.

231 many open questions remain, elucidating how cells repair themselves is important for our mechanistic

232 This shows that epithelial cells respond to minimal wounds in a collective fashion

233 We identified autophagy as a pivotal cell response determining the efficiency of AAVs intrace

234 isms by which noninflammatory SF modulate Th cell responses and to determine the immunosuppressive ef

235 ponses in preclinical models, particularly T cell responses, remain sparse.

236 ors and their microenvironments using single-cell RNA-seq from 11 primary colorectal tumors and match

237 ity with the risk of being eliminated by the cell's cytosolic immune defence.

238 However, little is known about how cells sense and respond to mechanical compression.

239 Technical advances in single-cell sequencing data and their application to greater sa

240 Moreover, residual CD28-deficient TFR cells showed a diminished suppressive capacity as assess

241 conjunctival, corneal, retinal, and scleral cells, similar to the behavior observed in macrophages.

242 xCreER(T2)-driven)-specific or smooth muscle cell (SMC, SmmhcCreER(T2)- or TaglnCre-driven)-specific

243 proliferation, is common in newly arising T cells (so-called "recent thymic emigrants") in adults, a

244 Cell-specific labeling of RNA can be profiled and imaged

245 ns, advances in DNA sequencing indicate that cell-specific variants affect a number of phenotypes and

246 However, simultaneous M-cell spikes generated through direct current injection w

247 nt information across a variety of mammalian cell state transitions.

248 investigated this phenomenon by stratifying cell subpopulations based on transcriptome profiling of

249 dependent phenotypic changes in blood immune cell subsets that occur following trauma, including indu

250 he biorecognition of complementary motifs at cell surface resulting in receptor crosslinking and apop

251 of interactions in bio-molecular studies and cell-surface analysis without the need for labeling proc

252 liferation and differentiation of stem cell, cell survival/death, and cellular metabolism under both

253 MRD detection method, phenotype/genotype (B cell, T cell, Philadelphia chromosome), and EFS and OS.

254 Highly efficient colored perovskite solar cells that exploit localized surface plasmon resonances

255 n we show in a diverse array of human cancer cells that IMP2 overexpression stimulates and IMP2 elimi

256 tly to excess centrosomes than do most tumor cells-they undergo senescence in vascular sprouts and ve

257 Fragment-based screening in human cells thus provides an extensive proteome-wide map of pr

258 ased transmembrane assemblies that connect a cell to its extracellular matrix (ECM).

259 ho-deficient LDHA Y10F sensitized the cancer cells to anoikis induction and resulted in attenuated ce

260 expression predicts the sensitivity of tumor cells to cytotoxic treatments can play an important role

261 to greater samples is revealing substantial cell-to-cell variation in expression levels and propagat

262 series of chemical analogs that reduce host cell toxicity while maintaining blood-stage and gametocy

263 ere, we have characterized nuclear and whole cell transcriptomes in mouse single neurons and provided

264 iously reported that HCA2 in A431 epithelial cells transduced Gbetagamma-protein kinase C- and Gbetag

265 treated with allogeneic haematopoietic stem cell transplantation on a compassionate basis in four Eu

266 rofiling of 144 single LNCaP prostate cancer cells treated or untreated with androgen after cell-cycl

267 hese cells into CD4+CD25+FoxP3+ regulatory T cells (Tregs).

268 Strikingly, cGAMP exerts cell-type-specific anti-inflammatory effects on macropha

269 on factors, allowing us to better understand cell-type-specific regulation of inflammation mediators

270 profiling regarding other cells demonstrated cell-type-specific synthesis of, among others, eicosanoi

271 provides new understanding of how different cell types are maintained in the adult lung.

272 on pathway found in most if not all metazoan cell types characterized to date.

273 mensional (3D) culture model including these cell types for investigating brain functions.

274 implicated in the biology of different stem cell types, yet they have not been studied in HFSCs.

275 lar stores and has an important role in many cell types.

276 quivalent between control and EVL/VASP dKO T cells upon alpha4 integrin blockade.

277 r-field planar ultra-thin ThermoPhotoVoltaic cells using surface-plasmon-polariton thermal emitters,

278 ter samples is revealing substantial cell-to-cell variation in expression levels and propagation of t

279 ual processing in VGluT3-expressing amacrine cells (VG3-ACs) in the mouse retina.

280 Anchoring anti-PEG antibodies on cells via variable-length tethers for cell-based sandwic

281 nd (iii) the ND coatings selectively promote cell viability.

282 d with remarkable expansions of protease and cell wall gene families, while divergent infection strat

283 activates protein kinase D1 (PKD1) in tumor cells, we investigated the effect of excitotoxicity on n

284 As carmaphycin B is toxic to mammalian cells, we synthesized a series of chemical analogs that

285 rophic-like scars, whereas few CD26-positive cells were present in the regenerated gingival wounds.

286 ellular free calcium imaging showed that the cells were still viable.

287 Results Liver endothelial cells were successfully isolated, cultured, and expanded

288 isplacements only along the long axis of the cell, where molecules experience the least confinement,

289 SFP1 is induced in stressed glucose-grown cells, whereas RTG3 is upregulated in stressed lactate-g

290 In conclusion, CMMPs act as 'synthetic stem cells' which mimic the paracrine and biointerfacing acti

291 ke the other 14 known galectins in mammalian cells, which have dimeric or tandem-repeated CRDs enabli

292 terleukin (IL)-33 released from breast tumor cells, which is crucial for the induction of IL-13(+) Th

293 ed tumor-cell colonies in coculture with PC3 cells, which might boost tumor stem-like properties.

294 y, CpG increased the number of circulating B cells, which produced elevated amounts of tumor necrosis

295 itor restores regorafenib sensitivity in CRC cells with intrinsic or acquired resistance.

296 d1, including follicular and marginal zone B cells with natural autoreactivity.

297 The treatment of cells with pharmacological inhibitors, such as nonsteroi

298 n light chain editing occurred, generating B cells with up-regulated Nod1, including follicular and m

299 expression in small sublineages (one to four cells) without radiation damage.

300 ation depend on the transformation status of cells.-Yu, Z., Ruter, D.