ライフサイエンスコーパス: cell activity

1 ulatory programs limiting cytotoxic CD8(+) T cell activity .

2 population and an increase in in vitro stem cell activity.

3 OA-NO2 is capable of enhancing regulatory T-cell activity.

4 tinemia, hemophagocytosis, and diminished NK cell activity.

5 between IL-32 and IL-15 and their role in NK cell activity.

6 for diseases characterized by dysregulated B cell activity.

7 leotide exchange factors known to regulate T cell activity.

8 s that were associated with increased immune cell activity.

9 LA-4 immune checkpoints inhibit antitumour T-cell activity.

10 ynamic responses, neuroinflammation and stem cell activity.

11 for Nedd4-2 and Ndfip1 in IgE-dependent mast cell activity.

12 ation, and the age-dependent decline in stem cell activity.

13 with inactive Wnt signaling and robust stem cell activity.

14 high-throughput screening and understanding cell activity.

15 stasis in vivo, and this was intrinsic to NK cell activity.

16 ndocrine lineages, while retaining some stem cell activity.

17 ral positioning of individual and group-wise cell activity.

18 ify the MR as a direct regulator of CD8(+) T-cell activity.

19 a crucial role in the regulation of RGL stem cell activity.

20 ganize tumor microenvironments to regulate T-cell activity.

21 gammadelta T cells through altered dendritic cell activity.

22 an important role in the regulation of stem cell activity.

23 ds that potentially modulate stem/progenitor cell activity.

24 ASP, and other hand as a modulator of immune cell activity.

25 d by stress and is inversely predicted by OH cell activity.

26 ryptophan into metabolites that inhibit T -: cell activity.

27 inhibition as critical regulators of granule cell activity.

28 ism of HSC-mediated augmentation of innate B-cell activity.

29 P-competitive GSK-3beta inhibitors with good cell activity.

30 llergic responses depend on deregulated mast cell activity.

31 Ptpn11 signaling a key function in satellite cell activity.

32 ignificantly more speed modulated than ocean cell activity.

33 mmatory Th1 response and natural killer (NK) cell activity.

34 uropeptide Y (NPY), which stimulates OE stem cell activity.

35 disease (GD) and is capable of regulating B-cell activity.

36 ar dataset that is linked to functional stem cell activity.

37 ates that contribute to increased metastatic cell activity.

38 luble NKG2D ligand can enhance anti-tumor NK cell activity.

39 sary for the generation and function of grid cell activity.

40 ogically relevant for the regulation of beta-cell activity.

41 eported to modulate myelopoiesis and myeloid cell activity.

42 ue, consistent with their differential whole-cell activity.

43 n a concentration-dependent restraint of the cell activity.

44 e an immunologic sanctuary protected from NK-cell activity.

45 s with Six2 and Myc to control self-renewing cell activity.

46 tion and could inappropriately enhance T reg cell activity.

47 er chronic stress changes hematopoietic stem cell activity.

48 t as it is disrupted by perturbing pyramidal cell activity.

49 ting cytotoxin, VacA, which inhibits human T cell activity.

50 eceptors significantly impaired antiviral NK cell activity.

51 contribute to the regulation of apical stem cell activity.

52 ng networks of target genes that orchestrate cell activity.

53 niches and systemic cues that regulate stem cell activity.

54 boost induced strong virus-specific CD4(+) T-cell activity.

55 vity in delta-cells but suppression of alpha-cell activity.

56 diposity, energy expenditure, and pancreatic cell activity.

57 hibiting CD8 T cells, enhancing regulatory T cell activity.

58 n supply, an environmental regulator of stem cell activity.

59 lk and the resulting tumor-associated immune cell activity.

60 vision pathway, independent from OFF bipolar cell activity.

61 k of CRC compared with subjects with high NK cell activity.

62 ng an anti-fibrotic rational by enhancing NK cell activity.

63 e processes ranging from bone growth to stem cell activity.

64 synaptic weights to produce predictive place cell activity.

65 n, while 3 sero (-) patients showed no CMV-T cell activity.

66 lity loci for CD and how these affect Paneth cell activity.

67 L-18 production, an important cytokine in NK cell activity.

68 functions as a matrikine regulating multiple cell activities.

69 ct more complex internal changes in oriented cell activities.

70 regulating tumor polyamines and enhancing NK cell activities.

71 which is accompanied by enhanced antitumor T-cell activities.

72 cell cycle but not genes that regulate stem cell activities.

73 Calcium imaging of granule cell activity 600-800 mum below the hippocampal surface

74 orrelate in vitro enzyme inhibition to whole cell activity, a better assay to evaluate a key factor,

75 propose that local signals regulate AT2 stem-cell activity: a signal transduced by EGFR-KRAS controls

76 he balance of principal tufted versus mitral cell activity across large expanses of the MOB in respon

77 cin (TLM) analogues that show improved whole cell activity against bacterial strains including methic

78 ering with PD1 signaling would augment CAR T-cell activity against solid tumors.

79 ol the location, duration, and strength of T cell activity against tumors.

80 sequent cortical disinhibition by reduced PV cell activity allows for excitatory ocular dominance pla

81 Notably, manipulating single place-cell activity also affected activity in small groups of

82 receptor is known to regulate bone and stem cells activities, although relatively little is known ab

83 effects of IgE to maintain and enhance mast cell activities and hence reduces the ability of mast ce

84 sor of B-cell lymphoma, is required for stem-cell activity and an aggressive form of acute myeloid le

85 ione) and idebenone, which show modest whole-cell activity and appear to act, at least in part, by ta

86 hypomagnesemia have reduced pancreatic beta-cell activity and are more insulin resistant.

87 LAG-3 has shown promise for augmenting CD8 T cell activity and boosting pathogen-specific immunity.

88 might be enhanced by modulation of dendritic cell activity and by a decrease in T-cell activation, ef

89 ure the dynamic signature of invasive cancer cell activity and cell-migration-induced ECM and collage

90 tend previous observations of papillary stem cell activity and collecting duct plasticity and imply a

91 udy uncovers new metabolic checkpoints for T cell activity and demonstrates that metabolic reprogramm

92 sought to verify the spatial nature of place cell activity and determine its sensory origin.

93 Intracellular metabolism is central to cell activity and function.

94 is pathway is important for regulating alpha-cell activity and glucagon secretion in human islets, we

95 reg cells in check, A20 thus integrates Treg cell activity and increased effector T cell survival int

96 of therapeutics is dependent on cytotoxic T-cell activity and is associated with a reduction in immu

97 critically important in the control of stem cell activity and maintenance of the identity of differe

98 refore, we explored the role of CCL7 in mast cell activity and motility in vitro and investigated the

99 fibrogenic cells, which influence satellite cell activity and muscle repair during hypertrophy and a

100 he KW cocktail modulated natural killer (NK) cell activity and neutrophil and monocyte phagocytosis i

101 e surface as the bacteria still maintain the cell activity and overproduce EPS.

102 or understanding the regulation of satellite cell activity and regeneration after muscle injury.Satel

103 e mouse and human insulin secretion and beta cell activity and show that reduced expression of key is

104 ute directly to LHb-induced inhibition of DA cell activity and support the widely held proposition th

105 ed the effect of the cell transfer on immune cell activity and tumor development.

106 Long-term LRCs lost stem cell activity and were a homogenous population of termin

107 ct on long-term lineage contribution or stem cell activity and, unlike G-CSF, did not impede recovery

108 The relationship between cells' activity and task features was mostly stable on s

109 erocytosis, negative regulation of dendritic cell activity, and dysregulated production of chemokines

110 CMV-specific CD8+ (CMV-Tc), CD4+ (CMV-Th) T cell activity, and natural killer (NK) cell number were

111 s a crucial regulator of tissue growth, stem cell activity, and tumorigenesis.

112 CMV-T cell activity, anti-CMV IgG, and NK cell-mediated antibo

113 Genetically encoded optical sensors of cell activity are powerful tools that can be targeted to

114 Among the most defining features of grid-cell activity are the 60 degrees rotational symmetry of

115 hlights macrophage ability to sustain cancer cell activities as a major concern that needs to be addr

116 o promote spatial group selection of granule cell activity as a function of timing of mossy fiber inp

117 resulted in elevated mammary stem/progenitor cell activity as judged by limiting dilution transplanta

118 acetate (which is known to affect CB glomus cell activity) as an agonist for the most highly abundan

119 rt novel mechanisms by which TRMs regulate T cell activities at tissue sites.

120 se-response relationship, suppressing mitral cell activity at high and low, but not intermediate, NE

121 unodeficiency is associated with decreased T cell activity because of a persistent autoimmune-mediate

122 n-parametric Mann-Whitney test to compare NK cell activity between subjects with no evidence of CRC a

123 ective was to determine the difference in NK cell activity between subjects with vs without CRC.

124 We found a significant difference in NK cell activity between the 23 subjects with CRC (based on

125 on-specific activity leads hippocampal place cell activity both spatially and temporally.

126 t has been implemented to provide stronger T-cell activity but carries the risk of creating undesired

127 cy by 8-fold and increasing anti-cancer stem cell activity by 50-fold.

128 t a feedback inhibition of IL-15-mediated NK cell activity by IL-32alpha.

129 opted a regenerative strategy to expand stem cell activity by incorporating a transit-amplifying popu

130 4 on HIV MDSC, and controlled CMV-specific T cell activity by limiting CMVpp65-IFNgamma production an

131 e can differentially influence PFC pyramidal cell activity by nAChR modulation of layer II/III hierar

132 demonstrated that effective increase in stem cell activity can be achieved by using growth factors de

133 suggest that increased coherence of Purkinje cell activity can facilitate mossy fibre-driven spiking

134 etabolism would provide a powerful look into cell activity changes as cells differentiate to all the

135 The material showing the highest cell activity compared to the reference cell culture pla

136 This MCH cell activity correlates with novelty exploration, is in

137 e first time that the local induction of B10 cell activity could inhibit periodontal inflammation and

138 d that a limited Th1 response and reduced NK cells activity could underlie the reduced pathology in t

139 Granule cell activity covaried trial by trial to form a redundan

140 OH cell activity decreased within milliseconds after eating

141 ghlighting alterations to intrinsic Purkinje cell activity, dendritic architecture and glutamatergic

142 ve chemogenetic silencing of natural GAD65LH cell activity depresses voluntary locomotion, and that G

143 rewards elicited markedly different granule cell activity despite identical stimuli and licking resp

144 trated a primary role for MafA in adult beta-cell activity, different from the embryonic importance o

145 ignaling that may be exploited to enhance NK cell activity during ageing.

146 larly, the clinical relevance of increased B cell activity during IFN-beta treatment is unclear.

147 rgize with adaptive signals to potentiate NK cell activity during infection or vaccination.

148 EC lineages and promotes stem and progenitor cell activity during intestinal epithelium repair postin

149 ignaling microenvironment that sustains stem cell activity during organ maintenance and regeneration.

150 duces aggression in mice, reduced DG granule cell activity during resident-intruder interactions.

151 pal replays are episodes of sequential place cell activity during sharp-wave ripple oscillations (SWR

152 The extent of NK cell activity during the innate immune response affects

153 In comparison, suppressing PV cell activity elevates the synchronization of spontaneou

154 ere can be applied to disentangle individual cell activities even in nutritionally complex environmen

155 is a potential target to improve cytotoxic T-cell activity.Grail is an E3 ubiquitin ligase that inhib

156 Subjects with low NK cell activity had a 10-fold higher risk of CRC compared

157 e, bats, and monkeys, and signatures of grid cell activity have been observed in humans.

158 age behaviour and macrophage-mediated cancer cell activity, human monocyte derived-macrophages were s

159 ment of OX40 signaling enhances helper CD4 T cell activity, humoral immunity, and parasite clearance

160 ABAergic neurotransmission sculpts principal cell activity in a relevant fashion.

161 enting support system is key to extending NK cell activity in a tumor environment.

162 ble stable measurement of neuronal and glial cell activity in behaving mice, we have developed fluore

163 re has been little study of persistent glial cell activity in brains of athletes with sports-related

164 al modulation similar to the pattern of time cell activity in CA1, and the same populations of cells

165 Because MHC-E is up-regulated to evade NK cell activity in cells infected with HIV, simian immunod

166 riments in rats that measured place and grid cell activity in different environments, and then assess

167 We recorded single-cell activity in dLGN of anesthetized marmoset monkeys.

168 ct signaling pathways that govern progenitor cell activity in homeostasis and disease.

169 ion using a specific siRNA improved CD4(+) T-cell activity in ICL, as this restored TCR-induced extra

170 on by therapeutic vaccination can enhance NK cell activity in individuals with chronic HIV-1 infectio

171 preclinical proof-of-concept of NKG2D CAR T-cell activity in mouse glioma models and demonstrate eff

172 ve interventions to unleash tumor-specific T-cell activity in patients who naturally develop them.

173 We recorded place cell activity in rats exploring morphing linear tracks t

174 indicating a protective role for normal stem cell activity in reducing myofiber strain associated wit

175 We propose that NOD coordinates cell activity in response to intrinsic and extrinsic cue

176 ent of Ag-specific T follicular helper (TFH) cell activity in rhesus macaques has not previously been

177 aling as an upstream factor controlling Treg cell activity in specific tissue environments.

178 KEY POINTS: The role of enteric glial cell activity in the acute regulation of epithelial barr

179 s of Alzheimer's disease impairs neural stem cell activity in the adult brain.

180 Here, we monitored cell activity in the anterodorsal thalamus (ADN), an are

181 echniques to evaluate lysosomal function and cell activity in the model system and super-resolution m

182 ymphocyte antigen 4 antibody that enhances T-cell activity in the tumour, and selective BRAF inhibito

183 neuronal circuitry, or the role of principal cell activity in these processes.

184 eviates the suppression of tumour-specific T cell activity in vitro and in vivo.

185 bition of dipeptide uptake inhibits CML stem cell activity in vivo.

186 C pathway, and decreased leukemia initiating cell activity in vivo.

187 al, efficiently enhancing anti-metastatic NK cell activity in vivo.

188 opy as the reference standard, a test for NK cell activity in whole blood samples identified patients

189 thelial and mesenchymal phenotypes have stem cell activity, in many cells that have lost epithelial c

190 MDA-MB-231 metastatic cell activity including cell invasion, migration, transe

191 rid cells in similar proportions, but island cell activity, including activity in a proportion of gri

192 le glomeruli evoked diverse modes of granule cell activity, including subthreshold depolarization, sp

193 mic activation of NRF2 suppresses effector T cell activities independently of Tregs and that NRF2 act

194 wever, oxidative stress is known to impair T cell activity, induce actin stiffness, and inhibit cell

195 Principal cell activity induces directional growth of spine head f

196 One cell activity influenced by H2O2 is motility [3].

197 a critical period during which the principal cells' activity influences filopodia formation/retractio

198 Previous studies showed that stem cell activity is affected by local, systemic, and enviro

199 to the hypothesis that the loss of satellite cell activity is also a cause of sarcopenia.

200 nsplantation studies show that germline stem cell activity is confined to the Tert(High) cKit(-) popu

201 NK cell activity is controlled by an array of germ line-enc

202 Precise regulation of stem cell activity is crucial for tissue homeostasis and nece

203 at the application of PD1CD28 to boost CAR T-cell activity is efficacious against solid tumors via a

204 interference in vivo, we find that the Agrp cell activity is essential for ethanol-induced overeatin

205 Each single cell activity is expressed as current spikes decaying wi

206 mor immunogenicity, the negative impact on T-cell activity is functionally important.

207 Precise control over engrafted cell activity is highly desired, as cells do not always

208 r, the effect of IL-15 signaling on CD4(+) T cell activity is incompletely understood.

209 xin-->D2 excitatory circuit and show that D2 cell activity is necessary for orexin-dependent innate r

210 signals and eating, and demonstrate that OH cell activity is rapidly controllable, across nutritiona

211 hannel in beta-cells to understand how alpha-cell activity is regulated by beta-cells.

212 In vivo studies have shown that Golgi cell activity is regulated by climbing fiber stimulation

213 How B1 cell activity is regulated remains unclear.

214 kemic cells endowed with leukemia-initiating cell activity (LIC).

215 The differential gene expression of cell activity marker (c-fos), early OPC (Olig1, Olig2.

216 An analysis of cell activity marker genes after stimuli exposure reveal

217 t pathogenic cells via enhanced regulatory T cell activity may provide therapeutic benefit.

218 behaviors that punctuate exploration, place cell activity mediates the one-trial encoding of ongoing

219 tic, in vitro data increasingly suggest that cell activity modulates vesicle content.

220 These results suggest that Purkinje cell activity not only represents step phase within each

221 nstrates that dynamic measurements of single-cell activities of translation regulatory motifs can be

222 Furthermore, this stem cell activity of lin-28 is independent of one well-known

223 ntiation of postsynaptic layer 2/3 pyramidal cell activity of male, but not female, mice, thus produc

224 h enables the analyses of individual granule cell activity over time and provides a powerful tool to

225 f pyramidal cells, thereby shaping pyramidal cell activity patterns.

226 es inhibit antigen-primed cytotoxic CD8(+) T cell activity, permitting growth of FAK-expressing tumor

227 Interfering with T-cell activity prevented clearance of LMP-expressing B ce

228 Although normal HD cell activity (Raleigh's r > 0.4) was recorded in contro

229 To determine whether grid cell activity reflects distance traveled or elapsed time

230 But whether glial cell activity regulates these functions acutely under ph

231 1 requirements for autoreactive and normal T cell activity regulation.

232 etermine the fMRI response, whereas granular cell activity-related mechanisms control the fMRI respon

233 from committed progenitor or mutipotent stem cell activity remains controversial.

234 activated IL-8 transcription and hepatic NK cell activity, respectively.

235 dforward sensory input to modulate principal cell activity selectively.

236 Of note, antiviral NK cell activity showed no significant correlation with NK

237 repetitive theta-frequency cycles of granule cell activity.SIGNIFICANCE STATEMENT Long-term synaptic

238 Furthermore, ganglion cell activity spanned an area much larger than predicted

239 ological self-tolerance; yet, excessive Treg cell activities suppress anti-tumour immune responses.

240 The NK cell activity test identified subjects with CRC with 87.

241 sphere capacity, criteria for assessing stem cell activity, than the Runx2-GFP(-) population.

242 ventricular dysfunction are matched by stem cell activities that could attenuate the myocardial effe

243 rt a powerful control over hippocampal place cell activities that encode external spaces.

244 intestinal tract is a site of intense immune cell activity that is poised to mount an effective respo

245 mossy fiber activity induces rhythmic Golgi cell activity that is synchronized by shared parallel fi

246 re associated with alterations in progenitor cell activity that may involve reduced Wnt signaling.

247 examples of sexually dimorphic somatic stem cell activity, the sex differences in intestinal stem ce

248 ontrol the timing, location, and dosage of T cell activity, thereby mitigating toxicity.

249 Delta(9)-tetrahydrocannabinol depressed GABA cell activity, therefore downstream dopamine cells will

250 on, and as these compounds may dampen immune cell activity, this factor limits the conclusions that c

251 ay directly stimulates lymphatic endothelial cell activity through a VEGFR3-independent mechanism.

252 orphic inhibitory receptor that modulates NK cell activity through interacting with HLA-A and HLA-B a

253 s) that could be capable of modifying mitral cell activity through the release of GLP-1.

254 In this study, we have observed single cell activity throughout the brains of larval zebrafish

255 escent center cells is thought to limit stem cell activity to directly neighboring cells, thus endowi

256 t that feedback inhibition suppresses Kenyon cell activity to maintain sparse, decorrelated odor codi

257 scribe the generation of CARs able to tune T-cell activity to the level of EGFR expression in which a

258 ogical processes that orchestrate individual cell activities toward the anatomical needs of an organi

259 root meristem gradually transition from stem cell activity toward differentiation.

260 an redirect and regulate FITC-specific CAR-T cell activity toward folate receptor (FR)-overexpressing

261 esting that DAC could positively modulate NK cell activity, trafficking, and tumor targeting.

262 APK and PI3K regulate dental epithelial stem cell activity, transit-amplifying cell proliferation, an

263 cylation decreases spontaneous CA3 pyramidal cell activity under basal and hyperexcitable conditions.

264 h following a burn injury requires satellite cell activity, underscoring the therapeutic potential of

265 Physiological recordings of ganglion cell activity using microelectrode arrays revealed a dec

266 beta-cells triggered a suppression of alpha-cell activity via gap junction-dependent activation of d

267 p2 protein of F. nucleatum to inhibit immune cell activity via TIGIT.

268 for detection of CRC in subjects with low NK cell activity vs subjects with higher NK cell activity w

269 NK cell activity vs subjects with higher NK cell activity was 10.3 (95% CI, 3.03-34.9).

270 Furthermore, during licking, stellate cell activity was anisotropic: the coordination was cons

271 cytokine synthesis, and pulmonary dendritic cell activity was assessed.

272 Primary cell activity was confirmed by examining cytokine and ce

273 a graft-versus-leukemia assay showed that T cell activity was maintained, and all of the leukemic ce

274 TanCAR T cell activity was more sustained but not more exhaustibl

275 ited startles [8, 9], we hypothesized that M-cell activity was necessary for S-start generation.

276 Grid cell activity was only weakly influenced by location, bu

277 he lesion and implantation of electrodes, HD cell activity was recorded while rats navigated within a

278 in vitro-generated EBV-specific cytotoxic T cell activity was reduced because of CD70 deficiency.

279 d IL-15 in the enhancement of natural killer cell activity was reported.

280 Defective NK cell activity was shown to increase susceptibility for v

281 tant mutant studies confirmed that the whole cell activity was the result of UppS inhibition, validat

282 ate-limiting molecule for cytotoxic CD8(+) T cell activity, was evident in the lamina propria of sero

283 GF mice have a distinct Ig repertoire and B cell activity, we aimed to evaluate whether this altered

284 To understand the structural basis of grid cell activity, we compare medial entorhinal cortex archi

285 ging and optogenetic manipulations of VIP(+) cell activity, we found that activating VIP(+) cells eli

286 To assess modulation of hair-cell activity, we reversibly activated or inhibited D1-l

287 tention effects on narrow- and broad-spiking cell activity, we show that attention alters cortical st

288 ating lymphocytes expressed TIGIT and that T cell activities were also inhibited by F. nucleatum via

289 Natural killer cell activities were clustered in clinical phases with b

290 liver damage (IA and ENEG phases), whereas T-cell activities were higher in all phases, compared to I

291 ppressed CD8(+) T-cell responses, aberrant B-cell activities were maintained due to expression of CD4

292 ion to maintain potent biochemical and whole-cell activity, whereas improved pharmacokinetic properti

293 s emerging for decentralized control of stem cell activity, whereby self-renewing behavior emerges fr

294 ng and dependent on donor IL-10-sufficient B cells activity, which induces regulatory T cells in the

295 cal models tumour-derived VEGF limits immune cell activity while anti-VEGF augments intra-tumoral T-c

296 ense, including inhibition of natural killer cell activity with ongoing lowering of Ig levels and CMV

297 specific stromal composition could impact T-cell activity, with potential impact on the optimization

298 ressed this question by monitoring CA1 place cell activity, with tetrodes, in control and KO mice lac

299 ic and highlights the need for limiting Treg cell activity within the tumor microenvironment.

300 perties of Janus particles to control single-cell activities without the need of complex magnetic man