ライフサイエンスコーパス: cell clone

1 phil autoantibodies, and 6 of 47 (12.8%) a T-cell clone.

2 ating metaphases within the malignant plasma cell clone.

3 ma production and proliferation by the CD4 T-cell clone.

4 growth and death rates of the individual CLL cell clone.

5 lonal evolution derived from a singular stem cell clone.

6 eive chemotherapy targeting the underlying B-cell clone.

7 e analyzed using a murine central memory Th1 cell clone.

8 3C(GT/GT)," using a gene-trap embryonic stem cell clone.

9 CR) isolated from a hemophilia A subject's T-cell clone.

10 also operates at the level of germline stem cell clones.

11 esistance to infection present in some CD4 T-cell clones.

12 nce of competitive somatic and germline stem cell clones.

13 ical role in the elimination of HPV-infected cell clones.

14 g the presence of similar Ara h 2-specific B-cell clones.

15 rithm that detected significantly expanded T cell clones.

16 s characterized by many, often very large, B-cell clones.

17 toire but does not eliminate self-reactive T cell clones.

18 l T cell, BDC-2.5, and other ChgA-specific T-cell clones.

19 ith either indirect or direct alloreactive T-cell clones.

20 city, thereby avoiding the need to isolate T-cell clones.

21 t the B cell repertoire with nonfunctional B cell clones.

22 n furthermore activate primary KIR2DS1(+) NK cell clones.

23 the isolation of dominant nonneutralizing B cell clones.

24 he efficient selection of high affinity GC B cell clones.

25 in combination with either direct/indirect T-cell clones.

26 both CD244 and TIM-3, but not PD-1, on CD8 T cell clones.

27 compared with virus-specific cytotoxic CD8 T-cell clones.

28 samples each contained a limited number of B cell clones.

29 lection of TNF-alpha-resistant leukemic stem cell clones.

30 myeloma plasma cell clones than MGUS plasma cell clones.

31 e selection of weakly self-reactive, naive T-cell clones.

32 nd evade lysis by HLA-restricted cytotoxic T-cell clones.

33 y higher activation of HIV-specific CD8(+) T-cell clones.

34 re iNOS-dependent and iNOS-independent CD4 T cell clones.

35 DCs in elicitation of HCMV-specific CD8(+) T-cell clones.

36 expansion of alloreactive and autoreactive T cell clones.

37 a large number of distinct HTLV-1-infected T-cell clones.

38 mokine secretion than "ineffective" CD8(+) T-cell clones.

39 n, somatic hypermutation, and selection of B cell clones.

40 peptide-stimulated PBMCs, and IFX-specific T cell clones.

41 to prevent the expansion of self-reactive B cell clones.

42 and IFN-gamma expression in plaque-derived T cell clones.

43 viral capacity of some HIV-specific CD8(+) T-cell clones.

44 nstitutive expression of HIV RNA in infected cell clones.

45 therapy are present in only some MGUS plasma cell clones.

46 s in emerging cisplatin-resistant tumours or cell clones.

47 lting in retention of the highest-affinity B cell clones.

48 on factor Bcl-6 and selected high-affinity B cell clones.

49 nd among highly expanded provirus-containing cell clones.

50 in Ca(2+) signaling in some lymphomas and T cell clones.

51 dditional members of the allergen-specific B-cell clones.

52 ulin reactive, MHC class-I-restricted CD8+ T cell clone (1E6) that can recognize over 1 million diffe

53 an individual clone basis, 14 of 53 CD4(+) T-cell clones (26%) recognized 6 distinct but overlapping

54 ns and differential reactivity of human MAIT cell clones according to the bacteria.

55 ce of proteasomal processing and immediate T cell clone activation upon stimulation with FLUX in solu

56 Wherever tested, all CD8(+) T cell clones against these novel lytic cycle epitopes rec

57 High-throughput sequencing and single-cell cloning analysis of the BCR repertoire revealed alt

58 tibodies are produced by a single expanded B-cell clone and carry distinct somatic mutations in the L

59 noma cell line stimulates a tumor-specific T-cell clone and elicits antigen-specific cells in vivo, y

60 This system uses stable cell clones and a variant of HIV-1JRCSF with three adapt

61 There, competition between B cell clones and among somatic mutants of each clone driv

62 a consequential reduction of autoreactive B cell clones and autoantibodies.

63 ug-specific responses from in vitro primed T cell clones and clones from hypersensitive patients were

64 -RLGL-WE14 tetramers bind to ChgA-specific T-cell clones and easily detect ChgA-specific T cells in t

65 We generated NONO-silenced HeLa cell clones and found that lack of NONO decreased cell g

66 ccurate partitioning of sequence data into B-cell clones and identification of the starting point of

67 Mechanistic experiments using human T-cell clones and lines are providing a clinically relevan

68 T1D patient-derived beta cell-autoreactive T cell clones and lines, but, when screening for pathogeni

69 Multiple T-cell clones and polyclonal lines having different avidit

70 tion and metastasis of drug-resistant cancer cell clones and supports the survival of drug-sensitive

71 ies has required the isolation of specific T-cell clones and their clonotypic TCRs.

72 On a longer time scale, the diversity of B cell clones and variants within individual GCs is also t

73 ction (5 h), cells were processed for single-cell cloning and analyzed for chromosomally integrated H

74 be sorted by flow cytometry, enabling single-cell cloning and expression of fully human immunoglobuli

75 ificity and limited diversity by both single-cell cloning and high-throughput sequencing techniques.

76 To define how B-cell clones are distributed in the body, we sequenced 93

77 We show that PPI-specific CD8 T-cell clones are mainly reliant upon cytotoxic degranulat

78 Although high- and low-affinity CD8(+) T cell clones are recruited into the primary response, the

79 alterations that affect whether MGUS plasma cell clones are responsive to anti-multiple myeloma ther

80 Within the GC, the highest affinity B cell clones are selected to mature into memory or plasma

81 However, none of the 75 expanded T cell clones assayed contained intact virus.

82 humoral immune response when an expanding B cell clone assumes multiple cell fates, including class-

83 By analysing the antibody-producing B cell clones at the protein, cDNA and gDNA levels, we cha

84 confirmed the presence of GVHD-associated T-cell clones at the site of the disease.

85 he target Ag for a highly diabetogenic CD4 T cell clone BDC-5.2.9.

86 clone generated in the skin, an abundant TCM cell clone bearing the identical TCR was present in the

87 egins with a diverse and expanded group of B cell clones bearing a wide range of antibody affinities.

88 expressed GATA3, nonetheless, a portion of T-cell clones both GATA3 and RAR-related orphan receptor C

89 CD1a mediates foreign Ag recognition by a T cell clone, but the nature of possible TCR interactions

90 e extent of fluctuation of dominant CD8(+) T-cell clones, but not of CD4(+) counterparts, correlated

91 ates a virtually unique IgH locus in every B cell clone by intrachromosomal recombination between two

92 Stable HTLV-1-producing HOS cell clones can be readily established and isolated.

93 e system is its ability to generate B- and T-cell clones capable of recognizing and neutralizing spec

94 For 3 distinct T-cell clones, CD79b specificity was confirmed through CD7

95 hod, no reactivity was observed by the CD8 T-cell clone, confirming no semidirect alloreactivity.

96 We report that a highly expanded CD4(+) T-cell clone contains an intact provirus.

97 al tissues, and absolute numbers of unique T-cell clones correlated with respective T-cell counts.

98 nnexin A2-specific Vdelta2(neg) gammadelta T-cell clones could be derived from peripheral blood monon

99 e topography of the expanding CMV-specific T-cell clones, deep sequencing allowed us, for the first t

100 asurements of three of these self-reactive T cell clones demonstrated a normal off-rate but a slow on

101 IGKV, and BCL6 genes from these D-specific B cell clones demonstrated that both CD27(-)IgM(+) and CD2

102 ysis of a set of 10 HLA-A*02:01-restricted T cell clones demonstrated that staining with pMHC multime

103 14 brain-infiltrating, JCV-specific CD4(+) T cell clones demonstrated that these cells use an unexpec

104 on TCR/CD8:pMHC avidity, as tumor-reactive T cell clones derived from patients vaccinated with the lo

105 Using a panel of diabetogenic CD4 T cell clones derived from the NOD mouse, we recently iden

106 PmpG(303-311)-specific multifunctional Th1 T cell clone, designated PmpG1.1, from an immune C57BL/6 m

107 utated common ancestor knock-in mice Env(+)B cell clones develop anergy and partial deletion at the t

108 ll markers (Foxp3(+) CD25(+)) and cultured T cell clones did not express a cytokine profile that indi

109 red by allospecific CD4 (indirect) and CD8 T-cell clones (direct) when cells were used.

110 stence of two independently regulated helper cell clones, directed against different epitopes of the

111 KK10-stimulated "effective" CD8(+) T-cell clones displayed significantly more rapid TCR signa

112 Finally, IL-10-producing drug-specific T cell clones downregulated the response of autologous eff

113 here the presence of a single autoreactive B cell clone drives the TLR7-dependent activation, expansi

114 ecific B cells and track the fate of these B-cell clones during SIT.

115 erm fitness advantage to a small number of T-cell clones (e.g., by an increased division rate or decr

116 st adalimumab is broad, involving multiple B-cell clones each using different combinations of V(D)J s

117 esting that they are generated by multiple B-cell clones, each initially comprising relatively few ce

118 % efficiency and a 96 +/- 4% postsort single-cell cloning efficiency.

119 me alterations 13q14-, 6q- and 12q+ in early cell clones, elimination of clonal populations following

120 ributing to developmental failure in somatic cell cloned embryos.

121 We isolated the B-cell clone encoding PGT121, which segregates into PGT121

122 azingly large, complex, and diverse memory B-cell clones, equipping the human immune system with a ve

123 mphoproliferation and generates many large B-cell clones, especially among non-class-switched memory

124 From a CD8(+) T cell clone established by stimulation of HLA-A2(+) CD8(+

125 t cotransfer of MPO431-439-specific CD8(+) T cell clones exacerbated disease mediated by MPO-specific

126 are the main sites where antigen-activated B-cell clones expand and undergo immunoglobulin gene hyper

127 Specific B-cell clone expansion involved the heavy chain variable r

128 T-cell clones expressing CCR4 and CCR9 migrated toward CCL

129 psular polysaccharide can recruit distinct B cell clones expressing characteristic idiotypes under ge

130 Furthermore, functional studies using NK cell clones expressing either the inhibitory receptor CD

131 immune response selectively expands B- and T-cell clones following antigen recognition by B- and T-ce

132 ble monitoring of pathogenic or protective T cell clones following HSCT and cellular therapies.

133 rameter to rapidly demark cytotoxic CD8(+) T cell clones for further TCR evaluation.

134 ns and efficient selection of low-affinity B cell clones for proliferative clonal expansion.

135 cribe how to isolate carbohydrate-specific T cell clones (for which we propose the designation 'Tcarb

136 We tracked the evolution of the lethal cell clone from the primary cancer to metastases through

137 vity to wheat, rye, and barley peptides as T-cell clones from adults with celiac disease.

138 Jug r 2-specific T-cell clones from allergic subjects mainly expressed GATA

139 m one effective and two ineffective CD8(+) T-cell clones from an elite controller into TCR-expressing

140 About half of the generated T-cell clones from children and adults reacted to unknown

141 en peptide recognition was similar between T-cell clones from children and adults.

142 hin the nTreg population, we isolated single-cell clones from each subset.

143 ther HLA-A2 or HLA-B7 were used to isolate T-cell clones from HLA-A*0201 and B*0702-negative individu

144 inst gluten by generating T-cell lines and T-cell clones from intestinal biopsies of adults and child

145 ctivity was observed for individual CD8(+) T-cell clones from mice bearing BPTF-silenced tumors.

146 ermore, we demonstrated that MiHA-specific T cell clones from patients with selective GVL reactivity

147 receptor beta (TCRB) gene sequencing of 15 T-cell clones from the severe HA subject revealed that all

148 s, we isolated and characterized 53 CD4(+) T-cell clones from within the residual pancreatic islets o

149 s primary CD8(+) T cell responses that, by T cell cloning from infectious mononucleosis (IM) patients

150 In single-cell clones, gene correction by helper-dependent adenovi

151 For every abundant TRM cell clone generated in the skin, an abundant TCM cell c

152 CD4(+) T cell clones, generated from HLA-DRB1*15:01 transgenic mi

153 sition, with particular patterns of memory B-cell clone generation in GC reactions.

154 Few surviving pre-B cell clones had acquired permissiveness to oncogenic sig

155 ological analyses to characterize the lethal cell clone in a patient who died of prostate cancer.

156 as the presence of an expanded somatic blood-cell clone in persons without other hematologic abnormal

157 recognition by an HLA-DR-restricted CD4(+) T-cell clone in response to cognate antigen presented by K

158 itopes are recognized by numerous distinct B-cell clones in a patient.

159 y samples, we found increased expansion of B cell clones in acute dengue patients, with higher overal

160 2-3 irAEs also had expansion of >/=55 CD8 T-cell clones in blood samples collected before the onset

161 We identified T-cell clones in GI biopsies in a heterogeneous group of 1

162 Because B-cell clones in MC and lymphomas derive from this B-cell

163 ures of TG2-specific PCs and their related B cell clones in peripheral blood.

164 moral TCR repertoire revealed expansion of T cell clones in the setting of neoantigen loss.

165 We show that co-existence of different cell clones in the tumor, as often found in experiments,

166 leads to the accumulation of autoreactive B cell clones in their blood.

167 to EBNA1- and LMP1-specific CD4+ and CD8+ T-cell clones in vitro.

168 et for three NOD-derived, diabetogenic CD4 T-cell clones, including the well-known BDC-2.5.

169 M5alpha transduction of virus-specific CD4 T-cell clones increased and prolonged their ability to sup

170 of the main factors limiting entry of new B cell clones into ongoing immunization-triggered GC respo

171 tor obtained from a hemophilia A subject's T-cell clone, into expanded human FoxP3(+) Tregs.

172 The BDC2.5 T cell clone is highly diabetogenic, but the transgenic mo

173 de novo priming of newly pathogenic CD8(+) T-cell clones is an alternate mechanism responsible for th

174 The repertoire of alloreactive T cell clones is distinct for every donor-recipient pair a

175 ng a large number of sufficiently abundant T cell clones is important for adequate protection against

176 n recognized by an HLA-E-restricted CD8(+) T cell clone isolated from an Mtb latently infected indivi

177 onfirmed that 17% (range, 13%-33%) of CD8+ T cell clones isolated from 4 vaccinated patients by limit

178 We found that diabetes-inducing CD4 T cell clones isolated from nonobese diabetic mice recogni

179 Tetramer-positive T-cell clones isolated from T1D subjects that responded to

180 at promotes outgrowth of pre-existing tumour cell clones lacking highly antigenic mutant spectrin-bet

181 protein-specific Tim-3(+) encephalitogenic T-cell clone (LCN-8), we found that conditioned medium fro

182 d recognition by the H-2D(b)/Trh4-specific T cell clone LnB5.

183 Aspergillus-specific T-cell clones mainly exhibited a T-helper cell 1 phenotype

184 The latter might originate from normal B-cell clones manifesting activation-induced cytosine deam

185 s suggest that chemotherapy adapted to the B-cell clone may constitute an efficient strategy for C3G

186 that targeting of specific epitopes and/or T-cell clones may be a promising approach to achieve toler

187 off) of tumor-specific vaccine-induced CD8 T cell clones (n = 139) derived from seven melanoma patien

188 PBMC and T-cell clones (n = 570, 84% CD4(+)) from blood of piperaci

189 had reconstituted from an epidermal CD8(+) T cell clone of an HLA-C*06:02-positive psoriasis patient

190 In line with this, a highly HBV permissive cell clone of HepAD38 cells showed a prominent associati

191 Further, T cell clones of tetramer-sorted memory cells of healthy i

192 We found that two recurrent Treg cell clones, one prevalent in prostate tumors and the ot

193 results in the emergence of resistant cancer cell clones only in the presence of IFN-gamma within the

194 We show that large B-cell clones partition into two broad networks-one spans

195 ults suggested that expansion of >/=55 CD8 T-cell clones preceded the development of severe irAEs.

196 loidosis is caused by a usually small plasma cell clone producing a misfolded light chain that deposi

197 kemia (CLL) is a disease in which a single B-cell clone proliferates relentlessly in peripheral lymph

198 quirement for expansion of many individual T cell clones, rather than merely expansion of the entire

199 re further characterized, and specific CD8 T-cell clones recognized both peptide-pulsed target cells

200 patient-derived preproinsulin-specific CD8 T-cell clones recognizing either an HLA-A2 (A*0201) or HLA

201 metric cluster analysis of multiple CD8(+) T-cell clones recognizing the identical HLA-B*2705-restric

202 veness of effective and ineffective CD8(+) T-cell clones recognizing the identical HLA-B*2705-restric

203 he factors that influence the diversity of B cell clones recruited into GCs are unclear.

204 The diversity of B cell clones recruited into germinal center (GC) response

205 hat symmetry, via extinction of damaged stem-cell clones, reduces the lifetime risk of accumulating p

206 The 20.1 mAb stimulated Vgamma2Vdelta2 T cell clones regardless of their functional phenotype or

207 Recognition by the CD8(+) T cell clone required N-terminal O-linked mannosylation of

208 mparing how MGUS and multiple myeloma plasma cell clones respond to these therapies are scarce.

209 These T-cell clones respond weakly to the peptide WE14, a natura

210 hat recognized the cross-reactive epitope, T cell clones responded robustly to cashew, hazelnut and/o

211 dentify how MGUS and multiple myeloma plasma cell clones responded to anti-multiple myeloma therapy i

212 Analysis of MR1T cell clones revealed specificity for distinct cell-deriv

213 Experiments with T-cell clones revealed that AgmTRIM5alpha could reproducib

214 Here, a single cell cloning revealed that HepAD38 cells, a widely-used

215 we show that tens to hundreds of distinct B cell clones seed each GC and that GCs lose clonal divers

216 Effective and ineffective CD8(+) T-cell clones segregated based on responses to HIV-1-infec

217 rization of a mutated CXCR7-expressing LNCaP cell clone showed altered intracellular signaling and re

218 ein analysis of an isolated corrected single cell clone showed secretion of the corrected type VII co

219 ypic and functional characterization of MR1T cell clones showed multiple chemokine receptor expressio

220 ic signaling between heterogeneous malignant cell clones, some of which expressed PDGFRbeta.

221 TL system model based on a CD8(+)/CD103(-) T cell clone specific of a lung tumor-associated Ag, we de

222 T-cell clones specific for dominant alpha- or omega-gliadi

223 CD4(+) T-cell clones specific to LANA, a protein expressed in all

224 We identified and enumerated unique CD8(+) T cell clones specifically induced by this vaccine through

225 Using a single-cell cloning strategy coupled with microarray analysis o

226 t chain amyloidosis a small, indolent plasma cell clone synthesizes light chains that cause devastati

227 Two VZV-specific CD4 T cell clones (TCC), recovered from the eye of a VZV uveit

228 s transferrable, antigenic-specific murine B-cell clone (TCL1-192) provides a platform to study the t

229 of response against multiple myeloma plasma cell clones than MGUS plasma cell clones.

230 Furthermore, EATL arose from a single T-cell clone that had been present for several years in AI

231 We isolated a new KS20-reactive Th1 CD4 T cell clone that rapidly transfers diabetes.

232 lexes (pMHCs), we examined the ILA1 CD8(+) T-cell clone that responds to a peptide sequence derived f

233 n protein MLL-AF9 to generate several single-cell clones that demonstrate resistance, in vitro and in

234 We compared three cell clones that differ only in the genomic integration

235 By definition, patients with MGRS have B-cell clones that do not meet the definition of multiple

236 XP3, allowing the comparison of autologous T-cell clones that do or do not express FOXP3.

237 Identification of specific antigens and T-cell clones that drive the disease will be the first ste

238 biopsies demonstrated a limited number of T cell clones that emerged at 3 months after vector admini

239 porting the identity of activated effector T cell clones that expand in response to the YFV 2 weeks p

240 this route, we discovered that preinfusion T-cell clones that expressed the IL7 receptor (IL7R) and c

241 r the knock-out revealed a mixture of NDUFA9 cell clones that harbored partial deletions of the mitoc

242 We isolated T-cell clones that recognized dominant peptides and assess

243 on of the MEL5 clone, but not other CD8(+) T-cell clones that recognized HLA A*0201-AAGIGILTV poorly.

244 In particular, large naive T-cell clones that were distinct from memory clones were f

245 We generated HLAnull K562 cell clones that were engineered to express CD1d and cos

246 of this study was to characterize distinct T-cell clones that were frequently and exclusively involve

247 d in vivo expansion of neoantigen-specific T cell clones that were reactive to mutant neopeptides fou

248 herent uncertainty in the number of B- and T-cell clones that will be missing from a blood or tissue

249 Here we show, using B6/Cast hybrid pre-B-cell clones, that a limited number of V segments on each

250 s for both the number and the abundance of T cell clones.) The causes of this observation are incompl

251 tropy underpinned the ability of the HA1.7 T-cell clone to cross-react with HA(306-318) presented by

252 nking specific characteristics of the plasma cell clone to response to different types of treatment,

253 sequencing of multiple isogenic chicken DT40 cell clones to precisely determine the consequences of B

254 similarities in the memory repertoire, the B-cell clones used in acute responses to ZOSTAVAX vaccinat

255 nd deposited from a fusion mixture as single-cell clones via FACS.

256 once the transcriptome of the Waldenstrom B-cell clone was compared with its normal phenotypic (CD25

257 ngly, the transcriptome of the Waldenstrom B-cell clone was highly different than that of normal CD25

258 e presence of neutrophil autoantibodies or T-cell clone was not associated with any specific clinical

259 The TCR from this high affinity T cell clone was rarely identified in ex vivo evaluation o

260 k of focused TCR-peptide binding, the ILA1 T-cell clone was still cross-reactive.

261 mice derived from a different embryonic stem cell clone was tested.

262 Using a high affinity tumor-specific T cell clone, we identified a panel of mimotope vaccines f

263 Using single-cell clones, we describe the morphology of these neurons

264 zing two independent conditionally mutant ES cell clones, we found that deletion of L1CAM dramaticall

265 By genomic sequencing of these T-cell clones, we identified a gene encoding a dominant T-

266 ding 7 L) new epitopes using memory CD8(+) T cell clones, we looked in HLA-matched IM patients and fo

267 sm and survival and maintains autoreactive B-cell clones, we performed ex vivo analyses of peripheral

268 s9 and TALEN targeted human pluripotent stem cell clones, we performed whole-genome sequencing at hig

269 using well-characterized UCP-specific CD4 T cell clones, we showed that hTERT processing and present

270 By using single-cell cloning, we identified genes that are associated wi

271 skin equivalents expanded from the corrected cell clone were grafted onto immunodeficient mice.

272 f the 70 most frequent putative pathogenic T cell clones were alphabeta T cells.

273 Jug r 2-specific T-cell clones were also generated, and mRNA transcription

274 KIR2DS2(+) KIR2DL2(-) NK cell clones were C1-reactive irrespective of their HLA-C

275 Several T-cell clones were cross-reactive, especially clones that

276 Thus, antigen-reactive skin TRM and LN TCM cell clones were derived from a common naive T cell prec

277 de, and only 44% of Art v 125-36 -specific T-cell clones were detected by the tetramer.

278 Autoreactive T cell clones were detected in the periphery of Foxn1 cond

279 y and multiple DCK or SLC29A deficient human cell clones were established with one clone becoming pre

280 by IFX-specific T cells, T cell lines, and T cell clones were evaluated at the mRNA and protein level

281 Cell clones were evaluated for their O/C differentiation

282 T-cell clones were generated from 4 hypersensitive patient

283 protein derivative of tuburculin-specific T-cell clones were generated.

284 The CD79b-specific T-cell clones were highly reactive against CD79b-expressin

285 (i) on average, approximately 2,000 CD8(+) T cell clones were induced by YF-17D, (ii) 5 to 6% of the

286 Small T-cell clones were often observed in T- and NK-cell tumors

287 Most (87%) top expanded lesional T-cell clones were shared with nonlesional tissues, and th

288 KRAS-mutated lung cancer cell clones were stably silenced for LSD1 expression.

289 We confirmed that MAIT cell clones were unable to respond to MR1(-/-) clones in

290 hat induced long-term remission, anti-Dsg3 B-cell clones were undetectable.

291 aggressive of these represented by AI4, a T cell clone with promiscuous Ag-recognition characteristi

292 In line with this interpretation, MAIT cell clones with distinct TCRs responded differentially

293 widely-used HBV-inducible cell line, contain cell clones with diverse permissiveness to HBV replicati

294 ncubation of KIR2DS1(+) fresh NK cells or NK-cell clones with HLA-C2(+) CCR7(+) lymphoblastoid cell l

295 functional diversity within tumor-specific T cell clones with identical TCR specificity.

296 btaining correctly targeted pluripotent stem cell clones with minimal unintended modifications.

297 In summary, IL-17-producing alphabeta T cell clones with psoriasis-specific antigen receptors ex

298 ould be recovered and maintained in culture, cell clones with simultaneously inactive GLT25D1 and GLT

299 eening of up to 300,000 individual hybridoma cell clones within less than a day.

300 In contrast, permanence of naive T cell clones would be determined by their affinity for co