ライフサイエンスコーパス: cell competition

1 that this promotes tumor growth, in part via cell competition.

2 ue and is required for both tumor growth and cell competition.

3 embryonic development through the process of cell competition.

4 mechanisms, and immune system mechanisms of cell competition.

5 by their neighbours through a process termed cell competition.

6 and non-autonomous mechanisms distinct from cell competition.

7 lleys and ridges through processes like cell-cell competition.

8 s) repopulate livers of normal recipients by cell competition.

9 opment, stem cell biology, regeneration, and cell competition.

10 ila S2 cells to investigate the mechanism of cell competition.

11 s cells and suggest an apoptosis pathway for cell competition.

12 red by DCs, providing a possible basis for T cell competition.

13 ulated in G1, and underwent apoptosis due to cell competition.

14 We show for the first time that cell-cell competition, a developmental paradigm, can be used

15 ht into this problem by showing that through cell competition, a fitness-sensing process that usually

16 Thus, cell competition acts as a tumor-suppressing mechanism b

17 ing and biophysical modeling and address how cell competition affects stem cell and tissue population

18 perplastic tumor suppressors, interfere with cell competition and elevate Dpp signaling.

19 f multiple stress signalling pathways before cell competition and find that these pathways collective

20 Modulating dmyc levels to create cell competition and hid-dependent cell death may be a m

21 homolog of the c-myc protooncogene, induces cell competition and leads to the death of nearby wild-t

22 s critical for scrib(-) clone elimination by cell competition, and experimental elevation of Yki acti

23 rant but viable cells are eliminated through cell competition, and the resulting loss of local tissue

24 (2017) proposes that this death results from cell competition arising from differences in cellular di

25 We report that cell competition between scrib(-) and wild-type cells pr

26 enes in HEK293 cells, gene silencing in THP1 cells, competition binding, and signaling studies with t

27 t only elimination of aberrant cells through cell competition but also proper organ-size control that

28 Importantly, we demonstrate that preventing cell competition, by expressing apoptosis inhibitors, re

29 Cell competition can occur when cells of different genot

30 occur in a number of pathological conditions.Cell competition causes the removal of less fit cells ('

31 During cell competition, cells with lower translation rates or

32 indings demonstrate that spatial context and cell competition cooperate to determine the fate of a mu

33 Two new studies highlight a role for cell competition during adulthood as a surveillance mech

34 Most mutations that rescue cell competition elevated Dpp-signaling activity, and th

35 omenon, which have shed light on how and why cell competition exists in developing and adult organism

36 ess does not involve Myc, a well-established cell competition factor.

37 ency of TR-->FO selection by increasing TR B cell competition for follicular entry in NOD mice.

38 te the role of the CD21/CD35 coreceptor in B cell competition for follicular retention and survival w

39 ells, resulting in somatic chimeras and stem cell competitions for gonadal niches.

40 Stem cell competition has emerged as a mechanism for selectin

41 Cell competition has led to the discovery of multiple pa

42 This process, referred to as cell-cell competition, has been described previously in Droso

43 Stem cell competitions have allowed the emergence of competit

44 Studies of cell competition in Drosophila have identified an active

45 results have implications for understanding cell competition in response to stresses involved in ste

46 teractions that recapitulate many aspects of cell competition in the developing wing.

47 We further discuss the clinical relevance of cell competition in the physiological processes of tissu

48 pressors, and novel cell death components in cell competition, in addition to the Dpp pathway implica

49 ll-cell communication pathway that regulates cell competition, in which fit cells eliminate less fit

50 ther for contribution to the adult, and stem cell competition, in which germline or somatic stem cell

51 iterature regarding the current landscape of cell competition, including classical pathways and model

52 Cell competition is a cell fitness-sensing mechanism con

53 Cell competition is a conserved mechanism that regulates

54 Cell competition is a form of cell interaction that caus

55 Cell competition is a homeostatic mechanism that regulat

56 Here, we show that cell competition is a mechanism regulating the fitness o

57 and antigen affinities impact interclonal B cell competition is a particularly relevant issue for ca

58 Cell competition is a quality control mechanism that eli

59 contains adenoma expansion, indicating that cell competition is essential for tumor growth.

60 We demonstrate that cell competition is executed via induction of the proapo

61 ed and can be constrained by host tissues if cell competition is inhibited, suggesting novel possible

62 An important implication of cell competition is that cellular fitness is not only a

63 Cell competition is the short-range elimination of slow-

64 The mechanism of this T cell competition is unclear, but may include competition

65 Cell competition is, therefore, a process that allows re

66 ogues have on proliferation serve to promote cell competition, leading to apoptosis in clones with a

67 ess and Nrf2 are linked to several diseases, cell competition may occur in a number of pathological c

68 Here we discuss the mechanisms by which cell competition measures and communicates cell fitness

69 We suggest that cell competition might occur during tumor development in

70 Here, we use in vivo B cell competition models and intravital imaging to examin

71 To model DC-specific T cell competition, normal mice were injected with one or

72 In rewired cells, competition occurred slowly and sometimes failed

73 ng donor allogeneic hematopoietic progenitor cell competition over limited numbers of host progenitor

74 However, T cell competition played only a minor role in limiting T

75 of bacteria and compounds before addition to cells (competition); pre-incubation of the cells with co

76 Tumour suppressor-mediated stem cell competition presented here could be a mechanism of

77 Lateral inhibition, a symmetrical cell-cell competition process, corresponds better to Waddingt

78 This process, known as cell competition, represents one example of a diverse gr

79 During cell competition, sporadic cell death occurs predictably

80 For instance, cell competition surveys the fitness of cells within epi

81 Here, we discuss the possible relevance of cell competition to cancer.

82 we report that this quality control process, cell competition, uses specific components of the evolut

83 Here we report an orthogonal mechanism of cell competition, whereby cells compete through mechanic

84 mpetition between cells occur in Drosophila: cell competition, whereby somatic cells within a growing

85 In particular, cell competition, which is a process in which viable cel

86 ess and Myc are major parallel regulators of cell competition, which may converge on signals that non

87 The phenomenon of "cell competition," which manifests in apoptosis of slowe