ライフサイエンスコーパス: cell cycle progression

1 processes, such as DNA damage responses and cell cycle progression.

2 acterial physiology: metabolism, growth, and cell cycle progression.

3 accumulation of CRL substrates and defective cell cycle progression.

4 ts in transcription, cell proliferation, and cell cycle progression.

5 ro-differentiation factors and inhibitors of cell cycle progression.

6 tant could overcome this barrier by resuming cell cycle progression.

7 multiple Pin1-regulated cancer pathways and cell cycle progression.

8 lic to anabolic metabolism, cell growth, and cell cycle progression.

9 , suggesting intrinsic circadian patterns of cell cycle progression.

10 romatin remodeling, synapse transmission and cell cycle progression.

11 f genes that regulate muscle development and cell cycle progression.

12 l-regulated kinase (ERK) phosphorylation and cell cycle progression.

13 igh AT recognition to serve as a mediator of cell cycle progression.

14 s known about how NAP activity is coupled to cell cycle progression.

15 eosomal interactions and suggests links with cell cycle progression.

16 ious inhibition of mitosis due to a delay in cell cycle progression.

17 in DIRAS3 expression is sufficient to impair cell cycle progression.

18 ofile of genes critical to BTIC stemness and cell cycle progression.

19 ve polymerases threaten genome stability and cell cycle progression.

20 histone acetylation patterns and for normal cell cycle progression.

21 ation of gene transcription, DNA repair, and cell cycle progression.

22 e regulation of KAT6 HATs and their roles in cell cycle progression.

23 SG2M-phase cyclins to minimize the noise in cell cycle progression.

24 wall organisation, sexual reproduction, and cell cycle progression.

25 duction in cell proliferation and a delay in cell cycle progression.

26 tivities, such as growth, proliferation, and cell cycle progression.

27 ibition of proliferation and restored normal cell cycle progression.

28 at PdRanBP may regulate cell division during cell cycle progression.

29 ated by Ipl1/Aurora B phosphorylation during cell cycle progression.

30 ss responses, developmental transitions, and cell cycle progression.

31 ation, chromosome alignment, cytokinesis and cell cycle progression.

32 fic signal transduction pathways to regulate cell cycle progression.

33 actor beta (TGFbeta), and directly represses cell cycle progression.

34 nscriptional signatures that correspond with cell cycle progression.

35 turbs the relationship between cell size and cell cycle progression.

36 different fission yeast cyclins for meiotic cell cycle progression.

37 illar components of the sarcomere throughout cell cycle progression.

38 ons during postnatal myocyte cytokinesis and cell cycle progression.

39 ad minimum effects on RB phosphorylation and cell cycle progression.

40 on assay confirmed the role of both genes in cell cycle progression.

41 which plays a central role in the control of cell cycle progression.

42 ng a requirement of ECD for normal mammalian cell cycle progression.

43 dynamics with meiotic telomere movement and cell cycle progression.

44 nockdown is associated with an impairment in cell cycle progression.

45 s of cancer, and its down-regulation impairs cell cycle progression.

46 phanous, and loss of either isoform perturbs cell cycle progression.

47 ays critical roles in signaling pathways and cell cycle progression.

48 es to transiently suppress DNA synthesis and cell cycle progression.

49 rease in the doubling time and impairment of cell cycle progression.

50 s and resulted in enhanced DNA synthesis and cell cycle progression.

51 utside of their canonical role in regulating cell cycle progression.

52 ellular processes, including cell growth and cell cycle progression.

53 en-induced DNA damage and maintaining proper cell cycle progression.

54 ical for extracellular matrix remodeling and cell cycle progression.

55 prisingly, human CDC14A is not essential for cell cycle progression.

56 t diminished TBET, GZMB, mTOR signaling, and cell cycle progression.

57 criptional blockade of genes associated with cell cycle progression.

58 gnaling at these stages may be important for cell cycle progression.

59 ls adapted to osmotic conditions and resumed cell cycle progression.

60 cogenic drivers promoting cell anabolism and cell cycle progression.

61 ring integrin adhesion assembly to permit G1 cell cycle progression.

62 s are necessary for kinetochore assembly and cell-cycle progression.

63 ubiquitin ligase, well known for its role in cell-cycle progression.

64 rmline proliferation and is not required for cell-cycle progression.

65 king nitrate assimilation and signaling with cell-cycle progression.

66 adapted tetraploid cells and their effect on cell-cycle progression.

67 family of transcription factors that govern cell-cycle progression.

68 ndings on CDK6's transcriptional activity to cell-cycle progression.

69 g and ZONAB (YBX3) function in Cdk4-mediated cell-cycle progression.

70 is necessary, but not sufficient, to change cell-cycle progression.

71 /p53, markedly accelerated proliferation and cell-cycle progression.

72 d reveals insights into the requirements for cell-cycle progression.

73 cyclins are central for timely regulation of cell-cycle progression.

74 nal regulation, cellular growth control, and cell-cycle progression.

75 the existence of size thresholds determining cell-cycle progression [1].

76 roliferation, increased apoptosis, defective cell cycle progression, a diminished ability to differen

77 al relationship between Notch signalling and cell cycle progression acts like a developmental clock,

78 r analysis provided basic information on how cell cycle progression affects the cell surface.

79 require the histone chaperone Asf1 to resume cell cycle progression after DSB repair.

80 not affect spindle organization and meiotic cell cycle progression after germinal vesicle breakdown.

81 s inhibited in basal INM still showed normal cell cycle progression, although neurogenic divisions we

82 ll proliferation with a significant delay in cell cycle progression and a marked decrease in tumor gr

83 on of exogenous ceramide, AC ablation blocks cell cycle progression and accelerates senescence.

84 mediated signaling, monolayer proliferation, cell cycle progression and anchorage-independent growth.

85 atic cancer cells to radiation by modulating cell cycle progression and apoptosis in several pancreat

86 n of atRA, mediated by Crabp1, in modulating cell cycle progression and apoptosis induction, and prov

87 cription of E2F-target genes associated with cell cycle progression and apoptosis.

88 d its function has been implicated in normal cell cycle progression and cancer metastasis.

89 ity establishment and maintenance as well as cell cycle progression and cell division.

90 re the regulatory and functional coupling of cell cycle progression and cell fate decision-making.

91 Brg1(flox/flox) alleles) negatively regulate cell cycle progression and cell growth.

92 , significantly promoted cell proliferation, cell cycle progression and cell migration, whereas a miR

93 ific inhibitor decreased cell proliferation, cell cycle progression and cell migration.

94 -1) is required for the coordination between cell cycle progression and cell size.

95 esin in MCF7 cells, but instead, compromises cell cycle progression and cell survival.

96 HIF-1alpha, as well as pronounced changes in cell cycle progression and cellular metabolism, thereby

97 indings indicate that GON4L is essential for cell cycle progression and division during the early sta

98 t in the coordination of DNA damage sensing, cell cycle progression and DNA repair pathways in eukary

99 DHX33 deficiency abrogates cell cycle progression and DNA replication and leads to

100 ar responses to alpha factor; and iv) blocks cell cycle progression and DNA replication.

101 This phenotype is associated with a delay in cell cycle progression and ectopic DNA elements in proge

102 the cyclin D1 promoter, suppressing the G1-S cell cycle progression and enhancing KSHV replication.

103 spond to antigenic stimulation by initiating cell cycle progression and functional differentiation.

104 covered a new function of Cdc6 in regulating cell cycle progression and has important implications in

105 t inhibitors cooperate to prevent viability, cell cycle progression and in vivo growth of melanomas h

106 Sexual reproduction impacted on cell cycle progression and induced an asymmetric respons

107 decrease of Notch signaling activity, halted cell cycle progression and induced apoptosis, thus affec

108 in vitro and in vivo cell growth, impairing cell cycle progression and inducing apoptosis, as a cons

109 ay elevated expression of genes that promote cell cycle progression and mitochondrial function relati

110 TRAIP is necessary for efficient cell cycle progression and mutations in TRAIP therefore

111 the activities of key proteins that promote cell cycle progression and oncogenesis.

112 l work examining viral protein modulation of cell cycle progression and oncogenic transformation reve

113 direct transcriptional regulator to promote cell cycle progression and plays an important role in dr

114 family, other members of which play roles in cell cycle progression and primary cilia function.

115 in Mus musculus and A. cahirinus, efficient cell cycle progression and proliferation only occurs in

116 t an important role for CCAR2 in maintaining cell cycle progression and promoting SCC tumorigenesis.

117 nhibitor of apoptosis protein that regulates cell cycle progression and resistance to apoptosis, is f

118 In budding yeast, cell cycle progression and ribosome biogenesis are depen

119 nt with a model where a relationship between cell cycle progression and self-renewal versus different

120 ion are probably driven by signals linked to cell cycle progression and shifts in photophysiology.

121 signaling pathway plays an important role in cell cycle progression and stress-induced apoptosis.

122 hat hRpn13 and Uch37 are required for proper cell cycle progression and that their protein knockdown

123 l outcomes have been attributed to increased cell cycle progression and the development of genomic in

124 has been demonstrated to play vital roles in cell cycle progression and the maintenance of genomic st

125 E2F7 and E2F8) function as key regulators of cell cycle progression and their inactivation leads to s

126 dicate that activator E2Fs are necessary for cell cycle progression and tumorigenesis and are also re

127 yet redundant role for isoforms 1 and 2, in cell cycle progression and tumorigenesis, possibly throu

128 cells from nucleolar stress, thus promoting cell cycle progression and tumorigenesis.

129 -18/WIPI1/2, and ATG-16.2/ATG16L all promote cell-cycle progression and are negatively regulated by t

130 ch as E. coli and B. subtilis, regulation of cell-cycle progression and cellular organization achieve

131 cell cycle regulated, and it is required for cell-cycle progression and DNA replication.

132 the checkpoint kinases 1/2, an aberrant G2/M cell-cycle progression and induction of myeloid differen

133 in-dependent kinase inhibitors in regulating cell-cycle progression and innate immunity in Arabidopsi

134 This finding suggests the coordination of cell-cycle progression and plant immune responses at mul

135 The APC/C controls both cell-cycle progression and postmitotic processes through

136 defined aneuploidy exhibit heterogeneity in cell-cycle progression and response to environmental per

137 unctions non-cell-autonomously to facilitate cell-cycle progression and stem cell proliferation.

138 vidence indicates a close connection between cell-cycle progression and the plant immune responses.

139 tein 3 (IGFBP3), and that this regulates SCC cell-cycle progression and tumor growth in vivo Furtherm

140 try that coordinate polar morphogenesis with cell cycle progression, and also act on the master cell

141 of GAS5-AS1 had no effect on proliferation, cell cycle progression, and apoptosis, it dramatically d

142 al role in multiple cell signaling pathways, cell cycle progression, and cell growth, and PI3K inhibi

143 that mechanisms regulating mRNA translation, cell cycle progression, and gene expression differ from

144 wed increased metastatic potential, enhanced cell cycle progression, and greater levels of integrin-F

145 ny formation, elicited S phase arrest during cell cycle progression, and induced both intrinsic and e

146 E2F1 is well known to promote G1 cell cycle progression, and the loss of E2F1 in SmgGDS-d

147 including transcription, DNA damage repair, cell-cycle progression, and apoptosis.

148 29Y is a hypomorph that cannot fully support cell-cycle progression, and AURKC p.Y248* fails to local

149 ed with proliferative breast tumor subtypes, cell-cycle progression, and DNA replication.

150 Wnt signaling, including high cell motility, cell-cycle progression, and the overexpression of Wnt ta

151 bility, resulting in increased apoptosis and cell cycle progression anomalies during early developmen

152 ons in genes implicated in the regulation of cell cycle progression, apoptosis, and T-cell developmen

153 tential thresholds of growth factor-mediated cell cycle progression appeared to be heterogeneous with

154 Furthermore, we show that growth and cell cycle progression are arrested in cells infected wi

155 these, the molecular pathways that restrict cell cycle progression are critical to the maintenance o

156 he central regulators that govern eukaryotic cell cycle progression are cyclin-dependent kinases (CDK

157 reds of kPa, T cell metabolic properties and cell cycle progression are only increased by the highest

158 How growth, microtubule dynamics, and cell-cycle progression are coordinated is one of the uns

159 cyclin-dependent kinase 2 (CDK2), regulates cell cycle progression as cells exit quiescence and ente

160 profiling identified CDC25B, a regulator of cell cycle progression, as one of the three RNA species

161 of cellular processes, including apoptosis, cell cycle progression, as well as stem cell renewal.

162 roblasts (MEFs) is impaired due to defective cell cycle progression, associated with reduced cyclins

163 dling of DCLK1 with microtubules and blocked cell-cycle progression at G2-M phase in hepatoma cells v

164 NIPA plays a role in cell cycle progression, but the functional consequences

165 ate malignant cell motility, metastasis, and cell-cycle progression, but is poorly characterized in h

166 ion of PCP proteins coincides precisely with cell-cycle progression, but the mechanisms coordinating

167 the CaMKK-like protein kinase Ssp1 promotes cell cycle progression by activating the ARK Cdr2 accord

168 t kinase (CDK) inhibitor p27, which inhibits cell cycle progression by binding cyclin A- and cyclin E

169 work provides insight into the regulation of cell cycle progression by specific N-glycan branching pa

170 cay by CRISPR-Cas9 knockout of TSN inhibited cell cycle progression by up-regulating a cohort of miRN

171 Cyclin D and CDK4/6 play a key role in cell-cycle progression by phosphorylating and inactivati

172 In the fat body, dE2F/dDP limits cell-cycle progression by suppressing DNA damage respons

173 n-RING E3 ubiquitin ligase that orchestrates cell-cycle progression by targeting cell-cycle regulator

174 se results suggest that in addition to drive cell cycle progression, CDK also targets RNF4, which is

175 lular matrix remodeling (Timp3, Adamts9) and cell cycle progression (Cdkn1a, Cdkn2b, Cenpj, Tubb4a),

176 pression in GC B cells including pathways of cell cycle progression, cell death and proliferation, an

177 hanges in IRS2 levels result in increases in cell cycle progression, cell survival, and beta-cell mas

178 Growth, cell cycle progression, chloroplast replication, fatty a

179 lso leads to chromosome congression defects, cell cycle progression delay, and defective chromosome s

180 ement of SOX-17 and RBBP8, genes involved in cell cycle progression, deserves further investigation.

181 c niches of an adult diurnal vertebrate, the cell cycle progression displays a robust circadian patte

182 rchitecture underwent dynamic changes during cell cycle progression, DNA methylation together with NS

183 chanisms of PI3Kalpha and CDK4/6 blockade on cell-cycle progression, DNA damage response, and immune-

184 ssembly and chromosome congression, and thus cell cycle progression during mouse oocyte meiotic matur

185 in regulating spindle organization, and thus cell cycle progression during mouse oocyte meiotic matur

186 ell cycle and is temporally coordinated with cell-cycle progression, ensuring the formation of the ri

187 significant inhibition in genes involved in cell cycle progression, especially G2/M checkpoint and m

188 )-complex genes was correlated with elevated cell cycle progression, expression of the E2F transcript

189 haracteristic HMGB4-dependent differences in cell cycle progression following cisplatin treatment.

190 s displayed increased cell proliferation and cell-cycle progression following LPS challenge.

191 ate a previously unrecognized requirement of cell cycle progression for the activation of the myogeni

192 SB) repair, is required during physiological cell cycle progression for the repair of replication-ass

193 Here, we identify cell-cycle progression gene 1 (CCPG1), an ER-resident pr

194 (s) regulates processes such as mRNA export, cell cycle progression, gene transcription, and DNA repa

195 dditionally, SON has been shown to influence cell-cycle progression, genomic integrity, and maintenan

196 processes, including embryonic development, cell cycle progression, glycogen metabolism, and immune

197 However, whether Ki-67 affects cell cycle progression has been controversial.

198 and tumorigenesis, mostly through regulating cell cycle progression, Hedgehog signaling, and WNT sign

199 biosynthesis and endomembrane biogenesis to cell cycle progression in Arabidopsis.

200 REST-p21 regulatory axis as a mechanism for cell cycle progression in cardiomyocytes, which might be

201 ular phenotype was observed while monitoring cell cycle progression in cells lacking MCPH1 function.

202 its role as a regulator of neural progenitor cell cycle progression in cerebellar development.

203 isingly, a recent study reported unperturbed cell cycle progression in Escherichia coli cells with an

204 irects periodic transcription and influences cell cycle progression in fission yeast.

205 Alterations in the regulation of cell cycle progression in HSCs invariably lead to the de

206 he ubiquitination of p21(Cip1) and regulates cell cycle progression in human osteosarcoma cells.

207 Cell cycle progression in mammals is strictly controlled

208 p27 regulates cell cycle progression in many cell types.

209 Environmental conditions modulate cell cycle progression in many cell types.

210 the dynamics of chromosome condensation and cell cycle progression in MCPH1 deficient cells under un

211 gy induced by boswellic acid analog BA145 on cell cycle progression in pancreatic cancer cells.

212 In line with uncontrolled cell cycle progression in SCLC, we find that CDC25A, B a

213 partment, which allows reconstruction of HSC cell cycle progression in silico.

214 Faithful cell cycle progression in the dimorphic bacterium Caulob

215 nslation of critical transcripts involved in cell cycle progression in the face of global eIF-4E-medi

216 How E6 promotes cell cycle progression in the presence of p53 and its ta

217 LncRNA-SARCC can suppress hypoxic cell cycle progression in the VHL-mutant RCC cells while

218 e cell cycle machinery and promoting optimal cell cycle progression in transformed cells.

219 PRL-3) demonstrated its requirement for G1-S cell-cycle progression in all breast cancer cells, but P

220 strate that JH4 is able to rescue defects of cell-cycle progression in both HGPS and aged cells.

221 However, the requirements for cell-cycle progression in human cells remain incompletel

222 prolongs mitotic length and interferes with cell-cycle progression in human cells, and it causes cel

223 be coordination of cellular organization and cell-cycle progression in model bacteria are not directl

224 s the primary mechanism by which Chk1 blocks cell-cycle progression in the early embryo and is an ess

225 nd purine-related metabolites and changes in cell-cycle progression in vitro and in vivo.

226 TbTK is essential for parasite viability and cell cycle progression, independently of extracellular p

227 gulates ERalpha, BCL2 and SKP2, impairs G1/S cell cycle progression, induces apoptosis and significan

228 gulation of NF90 in HCC cell lines can delay cell-cycle progression, inhibit cell proliferation, and

229 ing pathways pertinent to DNA damage repair, cell cycle progression, insulin-like growth factor signa

230 3 ubiquitin ligase complex and prevention of cell cycle progression into mitosis are required for LTR

231 rnal vertebrate, the circadian modulation of cell cycle progression involves both systemic and niche-

232 Cell cycle progression is carefully coordinated with a c

233 Coordination of endomembrane biogenesis with cell cycle progression is considered to be important in

234 eukaryotic cell cycle control proposes that cell cycle progression is driven by a succession of CDK

235 ormation regarding their roles in regulating cell cycle progression is limited.

236 Of note, we found that cell cycle progression is necessary for the DDR-resistan

237 In both mutants, cell cycle progression is remarkably delayed and DDR mar

238 Aberrant cell-cycle progression is a hallmark feature of cancer c

239 B. abortus cell-cycle progression is coordinated with intracellular

240 Instead, we showed that mycobacterial cell-cycle progression is regulated by an unprecedented

241 scription factor FoxM1 plays a vital role in cell cycle progression, is activated in numerous human m

242 sion plane orientation, together with proper cell-cycle progression, is critical for plant growth.

243 h the two kinases have very similar roles in cell-cycle progression, it has recently become apparent

244 to DZ proliferation rather than for allowing cell-cycle progression itself and must be regulated dyna

245 that unscheduled DNA replication and failed cell cycle progression leading to apoptosis are the mech

246 nregulates WEE1, a key negative regulator of cell cycle progression, leading to reduced phosphorylati

247 oss of pigmentation, and melanoblasts showed cell-cycle progression, migration, and cytokinesis defec

248 tant for many biological phenomena including cell cycle progression, mitochondrial respiration, and l

249 d an overall enrichment of genes involved in cell cycle progression, mitotic division, active metabol

250 restores B-cell follicle formation, impedes cell cycle progression of pretumor B cells, and eventual

251 f EPHB3 partially restores growth and normal cell cycle progression of TCF7L1-Null cells.

252 ngineered strains allowed the description of cell-cycle progression of Brucella abortus, including un

253 Furthermore, cell-cycle progression of Rev3L(-/-) mouse embryo fibrob

254 This study reveals effects of cell cycle progression on the expression of lineage spec

255 ors that regulate protein degradation during cell cycle progression or during stress responses.

256 llular localization of proteins required for cell cycle progression, pluripotency, and early differen

257 d cilia and is important for cell signaling, cell cycle progression, polarity, and motility.

258 ional studies, miR-126 was found to restrain cell cycle progression, prevent differentiation, and inc

259 g the N-myristoyltransferase NMT1 suppresses cell-cycle progression, proliferation, and malignant gro

260 by augmenting self-renewal, chemoresistance, cell-cycle progression, proliferation, and xenograft tum

261 ll, this work implicates hRpn13 and Uch37 in cell cycle progression, providing a rationale for their

262 -infective bloodstream trypanosomes affected cell cycle progression, reduced the abundances of rRNA a

263 or cell division because its ablation delays cell cycle progression, reduces cell size, and suppresse

264 duction of apoptosis in T-ALL cells, whereas cell cycle progression remained unaltered.

265 letal metabolism, intracellular trafficking, cell cycle progression, repair/maintenance, bioenergetic

266 Coordination of differentiation and cell cycle progression represents an essential process f

267 To assess the effects of noise on cell cycle progression requires not only extensive, quan

268 Double-knockout cardiac myocytes showed cell cycle progression resulting in increased DNA conten

269 ection increases cell death and dysregulates cell-cycle progression, resulting in attenuated hNPC gro

270 cation, telomere maintenance and elongation, cell cycle progression, signal transduction and cell pro

271 processes, including cytoskeletal dynamics, cell-cycle progression, signal transduction, gene expres

272 pher, CAPRA-S, and microarray version of the cell cycle progression signature did not predict respons

273 Rather, inhibition of HDAC8 delayed cell cycle progression, suppressed proliferation and ind

274 autophagy-Nrf2 (PAN) control axis coupled to cell-cycle progression that directs hESCs toward NE.

275 Throughout cell-cycle progression, the expression of multiple trans

276 , the ClpXP protease is essential and drives cell cycle progression through adaptor-mediated degradat

277 Here we show that cell cycle progression through mitosis following double-

278 ovirus Cre showed a critical role of ADA3 in cell cycle progression through mitosis.

279 Mechanistically, targeting EphA2 impaired cell cycle progression through S-phase via downregulatio

280 erexpression or Cdc25C downregulation delays cell cycle progression through the G2/M phase.

281 s an indirect regulator of transcription and cell cycle progression through the regulation of specifi

282 le to detect unrepaired SSBs, and then delay cell cycle progression to allow more time for repair; ho

283 dly consistent qualitative predictions about cell cycle progression under dynamically changing condit

284 f gene expression can occur independently of cell cycle progression, underlining its relevance for no

285 rganization of downstream events by impeding cell cycle progression until the necessary components ar

286 p of the dynamics of these regulators during cell-cycle progression versus cell-cycle exit.

287 GH3 cell proliferation through induction of cell cycle progression via activation of the Akt-GSK-3be

288 kinase Aurora A (AURKA) is controlled during cell cycle progression via two distinct mechanisms.

289 f antigen reexposure by transiently inducing cell-cycle progression via a pathway dependent on mTOR c

290 nance of haESCs, and highlighted that proper cell cycle progression was critical for the maintenance

291 paB response was delayed or repressed, while cell cycle progression was unimpeded.

292 th factor-induced Akt signaling dynamics and cell cycle progression, we could not predict the fate of

293 aradoxical effects of PIN1 on p27 levels and cell cycle progression, we hypothesized that PIN1 reliev

294 at chromosome condensation is uncoupled from cell cycle progression when MCPH1 function is lacking, r

295 n the control of stem cell proliferation and cell-cycle progression, which may have implications for

296 d-like cells, but not stromal cells, induced cell-cycle progression, which was amplified by MCL-speci

297 pancreatic cancer cell growth by attenuating cell-cycle progression, which was associated with transc

298 blockade significantly inhibited hepatocyte cell cycle progression while promoting a hypertrophic re

299 roliferation by suppressing CDKN1A, enabling cell cycle progression with a concomitant phosphorylatio

300 The coordination of cell cycle progression with the repair of DNA damage sup