ライフサイエンスコーパス: cell division

1 (CPC) is a conserved, essential regulator of cell division.

2 sults in the doubling of the genome prior to cell division.

3 pact of DNA damage associated with excessive cell division.

4 ch is essential for DNA replication prior to cell division.

5 s it determines the plane and orientation of cell division.

6 a prolonged period of time in the absence of cell division.

7 was not transferred to daughter cells during cell division.

8 ly germinating embryos, when there is little cell division.

9 nt stem cells maintain their identity during cell division.

10 hat regulate transcription, translation, and cell division.

11 ptidoglycan remodelling enzyme implicated in cell division.

12 enance as well as cell cycle progression and cell division.

13 xible tether essential for FtsZ functions in cell division.

14 aryotic cells that play an important role in cell division.

15 rough a continuous process of cell death and cell division.

16 totic spindle is critical to the fidelity of cell division.

17 itch from neurogenic to terminal patterns of cell division.

18 omosome segregation and orchestrate faithful cell division.

19 olecules and antioxidants that sustain rapid cell division.

20 tric inheritance of Ventx2 protein following cell division.

21 s for accurate chromosome segregation during cell division.

22 reduce gene activity incompletely or rely on cell division.

23 er supports the decisive role of survivin in cell division.

24 , a key enzyme involved in the regulation of cell division.

25 r cells that inhibits the rate of tumor stem cell division.

26 ental conditions regulate Cdr1 signaling for cell division.

27 nd remain attached to the chromosomes during cell division.

28 tal disorders involving defective asymmetric cell division.

29 e functions maintain genome stability during cell division.

30 ions to different aspects of development and cell division.

31 in V-based forces to promote the fidelity of cell division.

32 l that requires extensive remodelling during cell division.

33 umulative mitogenic stimulation required for cell division.

34 fic activity thereby regulating pneumococcal cell division.

35 from the absence of cytoplasmic dilution by cell division.

36 t both daughter cells inherit plasmids after cell division.

37 StkP, the central regulator of pneumococcal cell division.

38 apoptosis breaks feedback inhibition of stem cell division.

39 ibutes to cellular homeostasis by regulating cell division.

40 g and maintaining the mitotic spindle during cell division.

41 4 that sequesters it in the cytoplasm during cell division.

42 a liquid that dissolves and condenses during cell division.

43 dicating that Grb14 is a potent repressor of cell division.

44 ymmetric spindle positioning driving unequal cell division.

45 ry into the mammalian host and resumption of cell division.

46 l for accurate chromosome segregation during cell division.

47 processes such as polarity reorientation and cell division.

48 tle is known about the fate of cccDNA during cell division.

49 n machine that segregates chromosomes during cell division.

50 g-term memory can survive multiple rounds of cell division.

51 landscape as cells prepare their genomes for cell division.

52 of DNA sequence, which are heritable through cell division.

53 uides correct septal cell wall synthesis and cell division.

54 uplication until the appropriate time during cell division.

55 both the rate of peptidoglycan synthesis and cell division.

56 pindle pole bodies (SPBs)] are essential for cell division.

57 tially suggesting roles for such channels in cell division.

58 s required to prevent chromosome loss during cell division.

59 ropic RNA chaperone controlling pneumococcal cell division.

60 SUMOylation in septin filament bundling and cell division.

61 entially associated with DNA replication and cell division.

62 ases to permit chromosome segregation during cell division.

63 uity by orienting the mitotic spindle during cell division.

64 , to glycogen accumulation, and to distorted cell division.

65 with a radiation of cellulases implicated in cell division.

66 n by the hematopoietic cytokine FLT3L during cell division.

67 probably also reduces the number of lateral cell divisions.

68 lipogenesis and protein synthesis in mitotic cell divisions.

69 essential for this process than for somatic cell divisions.

70 continually replaced by the progeny of stem cell divisions.

71 tation, and only Cdk1 is essential for early cell divisions.

72 m cells, accompanied by increased horizontal cell divisions.

73 tion is terminal due to irreversible loss of cell division ability and is associated with genome ampl

74 cription factor networks that translate into cell division activity during the early development of t

75 ell elongation (anaerobic conditions) versus cell division (aerobic conditions) in the coleoptiles.

76 elopmental changes, regeneration of tissues, cell divisions, aging, and pathological conditions obser

77 ng view that flagella play a central role in cell division among protists that lack myosin II and add

78 integrity, cohesion and polarity, increased cell division and a distinctive form of ductal hyperplas

79 B cells undergo rapid cell division and affinity maturation in anatomically di

80 control critical cell-fate decisions (e.g., cell division and apoptosis) can function with such low

81 ls leading to mitotic catastrophe, defective cell division and apoptosis.

82 dent kinases (Cdks) are principal drivers of cell division and are an important therapeutic target to

83 our data uncover an intriguing link between cell division and cannibalism, of significance to both c

84 parasite faces several alternating events of cell division and cell differentiation in which exponent

85 Although both epithelial cell division and cell extrusion require Piezo1 at the s

86 he spindle assembly checkpoint that controls cell division and cell fate.

87 ead, it emerges from Sc-specific versions of cell division and cell merging that are shaped by cell e

88 Cell cycle regulation is pivotal for proper cell division and cellular differentiation in eukaryotic

89 is important for regulation of motility and cell division and changes over time.

90 zed, displayed symmetric distribution during cell division and could efficiently maintain pluripotenc

91 le to disrupt the vessel endothelium through cell division and detach into circulation.

92 pistils, where genes encoding regulators of cell division and development were most frequently down-

93 states are clonally distinct, stable across cell division and developmentally important in directing

94 cell cycles allows circadian clocks to gate cell division and DNA replication in many organisms, cir

95 s cellular processes, such as cell motility, cell division and endocytosis.

96 We conducted kinematic analyses of cell division and expansion to understand the impact of

97 essential for chromosome condensation during cell division and functions in regulating gene expressio

98 Centromeres are essential for cell division and growth in all eukaryotes, and knowledg

99 t the contact with APC was maintained during cell division and led to an unequal inheritance of LFA-1

100 pport the more energy-demanding processes of cell division and organogenesis of the new seedling.

101 vironment, cells alternate between phases of cell division and quiescence.

102 Similar defects in meiotic cell division and reproductive ploidy stability occur in

103 ting spore returns to a conventional mode of cell division and resumes vegetative growth, but the req

104 otic organelle that plays essential roles in cell division and signaling.

105 idermal keratinocytes, resulting in impaired cell division and squamous differentiation.

106 t regulatory pathway that orients progenitor cell division and supports neural development.

107 romatin disk periphery during this window of cell division and that CHMP7 can bind directly to the C-

108 ECROW (SCR), cooperatively direct asymmetric cell division and the patterning of root cell types by t

109 Repeated cell divisions and aging impair stem cell function.

110 n between the number of tissue-specific stem cell divisions and cancer risk of the same tissue sugges

111 Both oriented cell divisions and cell rearrangements are critical for

112 0/CD27 interaction by mAb induced asymmetric cell divisions and differentiation in AML blasts and AML

113 lationship between the number of normal stem cell divisions and the risk of 17 cancer types in 69 cou

114 tostella vectensis undergo rapid synchronous cell divisions and ultimately give rise to a diploblasti

115 se from failed cytokinesis, the last step of cell division, and are a key feature of syncytial archit

116 y important for resolving DNA tangles during cell division, and as such, it is a broad anticancer dru

117 inetics, fatty acid and cell wall synthesis, cell division, and cell shape.

118 r flow, we osmotically shock the cell during cell division, and find that the cell can actively adapt

119 a motor involved in intracellular transport, cell division, and neurodevelopment.

120 rval tissues undergo endoreplication without cell division, and the latest replicating regions occasi

121 via direct fate conversion in the absence of cell division, and their multipotency at the population

122 h processes including cell cycle, asymmetric cell division, apoptosis and actomyosin-regulation.

123 etic products that can no longer be used for cell division are redirected toward carbohydrates and tr

124 Asymmetric cell divisions are required for cellular diversity and d

125 We propose that cell division arrest is programmed in competent pneumoco

126 The ACC1 uORF is relevant for cell division because its ablation delays cell cycle pro

127 pan (RLS) of a cell-defined as the number of cell divisions before death-has informed our understandi

128 lytically inactive mutant of PBP 2B supports cell division, but in this background the normally dispe

129 aments into dynamic clusters is critical for cell division, but the interactions between protofilamen

130 m a discontinuous ring that drives bacterial cell division by directing local cell wall synthesis.

131 onal programs in HSCs and is reinforced over cell division by recursive interactions between transcri

132 ial strands during DNA replication; however, cell division can reinforce H3K27me3 coverage at target

133 Telomeres, which are involved in cell division, carcinogenesis, and aging and constitute

134 ents, allows an investigation of the role of cell division, chemotaxis, adhesion, and other parameter

135 meiosis, mitotic errors during post-zygotic cell division contribute to pervasive aneuploidy in huma

136 teractions are essential for Lon activity in cell division control.

137 ulation that persists at the membrane during cell division could serve as an internal cue for establi

138 Asymmetric cell division, creating sibling cells with distinct deve

139 bution of immunohistochemical markers of the cell division cycle (CDC) in 5 of the 16 neurogenic nich

140 Here, we investigate the cell division cycle 25 (Cdc25) dual-specificity phosphat

141 Cell division cycle 42 (CDC42) plays important roles in

142 ive agents of malaria, have evolved a unique cell division cycle in the clinically relevant asexual b

143 The cell division cycle is the process by which eukaryotic c

144 EE788 prevents entry into the S-phase of the cell division cycle.

145 hat the origin-recognition complex (ORC) and cell-division cycle 6 (Cdc6) proteins recognize and enci

146 size primarily modulates the duration of the cell-division cycle by controlling the G1/S transition k

147 ecular link between the cilia life cycle and cell-division cycle.

148 After stem cell division, daughter cells that exit the stem cell do

149 Moreover, dynamin mutants have a cell division defect due to the decreased stability of s

150 on, as well as sepF transcript abundance and cell division, demonstrating the utility of transcriptom

151 Asymmetric cell divisions depend on the precise placement of the sp

152 motility independent of the cell cycle, and cell division dependent on the cell cycle.

153 Translational control during cell division determines when cells start a new cell cyc

154 ecreate the observed trends, suggesting that cell divisions drive the robust emergence of CAM and fac

155 We discover that whereas cell divisions drive tissue expansion along one axis, th

156 ired from the "symmetry-breaking" periclinal cell divisions during the transition between stage I and

157 symmetric spindle positioning during unequal cell division.Early ascidian embryos have a cortical sub

158 Meiosis is a specialized cell division, essential in most reproducing organisms t

159 hylation, changes that were heritable across cell divisions even after the compound was removed.

160 tous bacteria Streptomyces undergo a massive cell division event in which the synthesis of ladders of

161 ribution by adding a constant length between cell division events.

162 Organogenesis occurs through cell division, expansion, and differentiation.

163 Despite evidence of increased Treg cell division, Foxp3 expression was not stably maintaine

164 rker for ABCs, were generated after multiple cell divisions from C57BL/6 donors but not from MHC clas

165 The central player in bacterial cell division, FtsZ, is essential in almost all organism

166 RNA (sRNA) DicF, i.e., the inhibitor of the cell division gene ftsZ, through chaperon protein Hfq-de

167 d by acetylated Skp2, resulting in polyploid cell division, genomic instability, and oncogenesis.

168 The pattern of cell division, growth and separation during leaf develop

169 omplex three-dimensional processes involving cell division, growth, migration, and rearrangement, all

170 ntinuous integrity during rapid and repeated cell divisions has never been directly addressed, partic

171 kinetics and a premature shift to asymmetric cell divisions impairing progenitor cell pool expansion.

172 e growth of the intercellular surface during cell division in a Caenorhabditis elegans embryo.

173 ctively, these data provide novel insight on cell division in actinobacteria and highlights a new cla

174 including stress responses, development, and cell division in all kingdoms of life.

175 lation cycles, including those that regulate cell division in bacterial pathogens.

176 factors that are best known for stimulating cell division in development and cancer.

177 PC biosynthesis and also reduces the rate of cell division in early leaf development.

178 Cell division in Escherichia coli is mediated by a large

179 Spatial regulation of cell division in Escherichia coli occurs at the stage of

180 he spatiotemporal regulation of motility and cell division in M. xanthus and illustrates how the stud

181 Cell division in most bacteria is mediated by the tubuli

182 eukaryotic tubulin, plays a central role in cell division in nearly all bacteria and many archaea.

183 vivo leads to misorientation of apical-basal cell division in nephron tubules.

184 Cell division in plant cells requires the deposition of

185 ) is a phosphatase normally activated during cell division in proliferating cells.

186 trusion and apoptosis in crowded regions and cell division in sparse regions.

187 ed lymphocytes undergo extraordinarily rapid cell division in the course of immune responses.

188 cell contact-dependent orientation of planar cell division in the mammalian embryonic skin.

189 hat the myosin 2 motor is required to orient cell division in the plane of a columnar epithelium.

190 mary roots than the wild type due to reduced cell division in the root apical meristem.

191 emory" cells resulting from the first CD8+ T cell division in vivo exhibited low and high rates of en

192 dressed this problem in the context of plant cell division in which a large number of TGN-derived mem

193 80) between cancer incidence and normal stem cell divisions in all countries, regardless of their env

194 with the estimated cumulative number of stem cell divisions in the associated tissue (p<0.05), althou

195 GN expression, resulted in randomly oriented cell divisions in the presence of uniaxial stretch.

196 used to expand HSC numbers ex vivo.Repeated cell divisions induce DNA damage in haematopoietic stem

197 the presence of antiviral therapy and during cell division induced by immune-mediated lysis of infect

198 ding, to our knowledge, new insight into how cell divisions influence CAM within a tissue.

199 Bacterial cell division involves the dynamic assembly of a diverse

200 Cell division is a complex process that requires precise

201 development, but whether it is required for cell division is contentious.

202 However, it is unclear how epithelial cell division is controlled to balance cell death at the

203 Mitotic rounding during cell division is critical for preventing daughter cells

204 ic nature of CAM and suggest that regulating cell division is crucial for tuning emergent collective

205 Cell division is mediated by filaments of FtsZ and FtsA

206 tage developing nephron tubules reveals that cell division is not oriented in the longitudinal (or pl

207 Oriented cell division is one mechanism progenitor cells use duri

208 Asymmetric cell division is the primary mechanism to generate cellu

209 stably restricted following asymmetric stem cell division is unclear.

210 d the upstream signal to initiate asymmetric cell division is unknown.

211 e kinase 1 (PLK1), an essential regulator of cell division, is currently undergoing clinical evaluati

212 s revealed that the dynamins are part of the cell division machinery and that they mediate their effe

213 ce that age may cause a breakdown in the egg cell division machinery.

214 In tubules, cell division may be oriented relative to two axes: long

215 new findings and compare these strategies to cell division mechanisms elucidated in model organisms.

216 esults in early mitotic entry that distracts cell division mode, leading to exhaustion of the progeni

217 much mutagenic damage is expressed following cell division, more-rapidly renewing tissues could be at

218 ize stochastically, a behavior essential for cell division, motility, and differentiation.

219 However, epithelial cell division must be tightly linked to cell death to pr

220 Here we show that mammalian epithelial cell division occurs in regions of low cell density wher

221 Oriented cell division (OCD) and convergent extension (CE) shape

222 aining cell size asymmetry during asymmetric cell division of Drosophila neuroblasts (NBs).

223 le orientation to polarity during asymmetric cell division of Drosophila neuroblasts.

224 on is involved in cell wall biosynthesis and cell division of Streptococcus pneumoniae.

225 reduction in growth rate and termination of cell division of the underlying epidermal cells.

226 During development, cell division often generates two daughters with differe

227 r of transcription (STAT) protein to promote cell division only in OB-ISCs.

228 The question of how cell division orientation is determined is fundamentally

229 ontacts, and define a mechanism that couples cell division orientation to intercellular adhesion.

230 ability and cancer by limiting the number of cell divisions, our findings suggest that extending the

231 onnection between phyllotaxis and the apical cell division pattern indicating a position-dependent pa

232 (137.5 degrees angle) and an unlinked apical cell division pattern.

233 esis, and yet the manner and degree to which cell division patterns affect airspace networks and phot

234 Our results indicate that cell division patterns influence the photosynthetic perf

235 haeal cells exhibited greater variability in cell division placement and exponential growth rate acro

236 issues, telomeres shorten with each round of cell division, placing a finite limit on cell growth.

237 and, after passage through Golgi/TGN to the cell division plane, transformed into fusogenic SNARE co

238 Both cell-cell adhesion and oriented cell division play prominent roles in establishing tissu

239 contradiction to the more gradual changes in cell division potential and differentiation that occur a

240 -autonomous co-ordination of cell growth and cell division previously observed in unicellular organis

241 in the frequency of symmetric and asymmetric cell divisions producing daughter cells capable of self-

242 Our data are complemented by cell division profiles and expression patterns of key ge

243 that negative feedback on the rate of tumor cell division promotes a permanent rise of the tumor ste

244 the first reported link between a GpsB-like cell division protein and factors important for escape f

245 to contain a disulfide bond is the essential cell division protein FtsN, but the importance of this b

246 Penicillin-binding protein PBP 2B is a key cell division protein in Bacillus subtilis proposed to h

247 During our studies on GpsB, a late cell division protein that controls activity of the bi-f

248 ation promotes aberrant dephosphorylation of cell division proteins via hyperactivation of the Mn-dep

249 f CX45 in reprogramming and may increase the cell division rate and result in an accelerated kinetics

250 Moreover, cell division rates in fed-batch cultures were positivel

251 The cell division regulator GpsB appears to co-ordinate PG s

252 The bacterial cell division regulators MinD and MinE together with the

253 Faithful segregation of chromosomes during cell division relies on multiple processes such as chrom

254 Faithfull genome partitioning during cell division relies on the Spindle Assembly Checkpoint

255 ges in actomyosin dynamics during asymmetric cell division remain unclear.

256 Construction of the cell plate during plant cell division requires the precise insertion of material

257 Successful execution of mitotic cell division requires the tight synchronisation of nume

258 PG synthesis at the cell division septum is necessary for constructing new p

259 Our data show that Gps1 is targeted to the cell division site in a biphasic manner, via Gin4 and Nb

260 osomal origin regions localize to the future cell division sites, before FtsZ.

261 other genes that are known to participate in cell division, specifically in the marginal regions of t

262 During cell division, spindle fibers attach to chromosomes at c

263 During cell division, spindle microtubules ensure an equal repa

264 To stimulate cell division, stretch triggers cells that are paused in

265 irradiation, but these cells fail to undergo cell division, terminating root growth.

266 behavior, which includes the orientation of cell division that defines the position of daughter cell

267 Meiosis is a specialized cell division that generates gametes, such as eggs and s

268 mitotic wave (SMW), a synchronized, terminal cell division that occurs several hours after passage of

269 e clock' for the rapid molecular changes and cell division that result upon re-oxygenation.

270 re, all PLT genes can activate the formative cell divisions that lead to de novo meristem establishme

271 NA disappears relatively quickly after final cell division, the GFP label persists for about 5 days,

272 During cell division, the mitotic kinesin-5 Eg5 generates most

273 During cell division, the spontaneous mutation rate is expresse

274 er cells in a sub-population of cells during cell division thereby generating prion-free [psi(-) ] ce

275 e of a repressive chromatin structure during cell division, thereby assuring stable target gene repre

276 mechanical stretch itself rapidly stimulates cell division through activation of the Piezo1 channel.

277 to OTS167, suggesting that this drug blocks cell division through an off-target mechanism.

278 Healthy enterocytes inhibit stem cell division through E-cadherin, which prevents secreti

279 mental processes, ranging from germline stem cell division to epithelial tissue homeostasis and regen

280 ession of progenitor cells from asynchronous cell division to G1 arrest and neuronal specification at

281 though in some cell types it is possible for cell division to occur in the absence of centrosomes, th

282 stochastic conversion of normally symmetric cell divisions to asymmetric and vice versa during devel

283 nsformation is complete before resumption of cell division, to provide this pathogen with the maximum

284 basal cells of mammalian epidermis whereupon cell division, transmembrane planar cell polarity (PCP)

285 me fungal xerophiles, metabolic activity and cell division typically halts between 0.700 and 0.640 wa

286 nates from differences in the number of stem-cell divisions underlying each tissue, leading to differ

287 detects and repairs damaged DNA and prevents cell division until the repair is complete.

288 A link between the epigenomic state and cell division versus cell elongation is suggested, as no

289 stability during developmentally controlled cell division via a network of protein-protein interacti

290 In order to test the importance of alternate cell divisions we manipulated zygotic transcription indu

291 indings suggest that mechanisms for rescuing cell division when the biochemical activity of PBP 2B is

292 d providing a mechanism for cells to trigger cell division when they reach a threshold concentration

293 force controls the outcome: stretch induces cell division, whereas crowding induces extrusion.

294 sonators remain internalized by cells during cell division, which enables tagging several generations

295 e subclades plays a highly conserved role in cell division, while the distribution of a second subcla

296 first part of this process is accompanied by cell division, while the second part is mainly associate

297 cell cycle, while preserving the coupling of cell division with cell growth, remain uninvestigated.

298 stability of all organisms requires precise cell division with proper chromosome orientation.

299 ow level of uniaxial stretch, which oriented cell divisions with the stretch axis irrespective of the

300 how epigenetic states are inherited through cell division, with intriguing mechanistic links to hist