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1 ation in a BRAF(V600E)-mutant human melanoma cell line.
2 s) and integrins, in a gp96-deficient murine cell line.
3 sitions in the AGM region and supportive OP9 cell line.
4 ZIKV isolate in a FcgammaRII-expressing K562 cell line.
5 of the IL-6-dependent B9 mouse plasmacytoma cell line.
6 n the estrogen-responsive MCF7 breast cancer cell line.
7 tacts in live cells from a monkey fibroblast cell line.
8 uantitatively determined and unique for each cell line.
9 n co-transfection experiments in a human RPE cell line.
10 in the human acute myeloid leukemia MOLM-13 cell line.
11 .3 nM) against a large number (93) of cancer cell lines.
12 and long-term rapamycin treatment in sarcoma cell lines.
13 erns in parental and NOTCH1-expressing C2C12 cell lines.
14 erative activities in acute myeloid leukemia cell lines.
15 lastoma and atypical teratoid rhabdoid tumor cell lines.
16 tory papillary and follicular thyroid cancer cell lines.
17 those that reduced viability of 6 human CCA cell lines.
18 genome-wide landscapes in a series of human cell lines.
19 sues as well as pancreatic and breast cancer cell lines.
20 oth endometriotic and endometrial epithelial cell lines.
21 d conjugate was studied in normal and cancer cell lines.
22 pressed in primary ATC samples and human ATC cell lines.
23 rowth inhibition in multiple patient-derived cell lines.
24 losing in three types of immortalized cancer cell lines.
25 ts in C57BL/6 mice in vivo and hematopoietic cell lines.
26 thout significantly affecting EGFR wild-type cell lines.
27 also measured expression by 15 human cancer cell lines.
28 using stably transfected, inducible isogenic cell lines.
29 inhibition of cell growth in acute leukemia cell lines.
30 oid precursor protein transgenic mice and AD cell lines.
31 6(+intron 2)) transcripts in CRC tissues and cell lines.
32 ase I hypersensitivity in one or more ENCODE cell lines.
33 t, and cell death in sensitive breast cancer cell lines.
34 ed and 344 EFO unique immortalized permanent cell lines.
35 poptosis and proliferation inhibition in AML cell lines.
36 ibroblast), and RAW 264.7 (mouse macrophage) cell lines.
37 ssibility were similar across hiPSC and hESC cell lines.
38 on was observed in MCC tumor tissues and MCC cell lines.
39 T and HDAC pathway blockade in hematological cell lines.
40 ased MAP3K13 mRNA in HNSCC tumor samples and cell lines.
41 aortic endothelial cells and lymphoblastoid cell lines.
42 , and induced cytotoxicity in a panel of AML cell lines.
43 xpression profiles for different tissues and cell-lines.
48 tive behaviour was conserved among different cell-lines: all nuclei showed a softer and more viscous
49 k-in of mutant PIK3CA (H1047R) in the MCF10A cell line, an important cell model for studying oncogeni
50 drove proliferation of a human cholangiocyte cell line and demonstrated potent wound healing in mice.
51 iRNA-mediated knockdown of KIF20B in a human cell line and fixed and live imaging, we show that KIF20
52 h alters enhancer activity in a mouse atrial cell line and in embryonic zebrafish and differentially
53 Ca(2+) concentration of HCT116 colon cancer cell line and modified the cytosolic Ca(2+) oscillations
54 RCA2 loss in a non-transformed human mammary cell line and see increased replication stress due to un
55 Nonetheless, systematic differences between cell line and tumor proteomes were apparent, attributabl
56 Dual-auristatin ADCs imparted activity in cell line and xenograft models that are refractory to AD
58 dy, using acute myeloid leukemia (AML) human cell lines and a custom CRISPR/Cas9 screening platform,
59 t KuQs are highly active toward the analyzed cell lines and almost nontoxic for healthy cell, indicat
60 r of STS subtypes, making development of STS cell lines and animal models representative of the diver
62 on simulated data as well as prostate cancer cell lines and cfDNA obtained from castration-resistant
64 entified gene were measured in 9 human liver cell lines and compared with expression profiles of its
67 phate (GTP) in untransformed and transformed cell lines and determine this phenomenon depends on the
68 human embryonic and induced pluripotent stem cell lines and have potential applications for both dise
72 titutively in a panel of basal breast cancer cell lines and in more than one third of basal tumors.
73 cardiac stress response using bioengineered cell lines and mouse models containing either isoform of
75 n effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cel
81 gy and in vitro culture of murine fibroblast cell lines and primary fibroblasts and human epithelial
84 le and female transgenic mice in vivo and in cell lines and primary neuronal culture derived from tim
88 s overexpressed in a panel of ovarian cancer cell lines and that MICU1 overexpression correlates with
91 signature drove clustering of breast cancer cell lines and tumors into the common subtypes and corre
92 and Western blotting-in several nonprostatic cell lines and xenografts of melanoma and small cell lun
94 the epithelioma papulosum cyprini [EPC] fish cell line) and in vivo (using rainbow trout fry) in a do
95 ific methylation and nucleosome occupancy in cell lines, and colon and tumor samples, and by benchmar
96 mouse models of colorectal cancer (CRC), CRC cell lines, and mouse and human normal and cancer colono
97 mphocytic leukaemia and mantle cell lymphoma cell lines, and patients treated with idelalisib, but no
98 enchymal transition in human prostate cancer cell lines, and stable overexpression of miR-194 enhance
99 bs) manufactured from immortalized mammalian cell lines are becoming increasingly important as therap
101 erimental models: the human-derived RPE-like cell line ARPE-19, cultured murine primary RPE cells, an
102 Using the mouse endothelial-derived EOMA cell line as a model of HE, we explored the regulatory e
104 re we demonstrate, using a variety of cancer cell lines as well as activated primary T cells, that cy
108 h has been hampered by limited human sarcoma cell line availability and the large number of STS subty
111 V replication and oncolysis in all resistant cell lines but only partially improve the susceptibility
112 ed cytotoxic activity against HeLa and HT-29 cell lines, but were inactive towards MRC-5 and MCF7.
115 lular cholesterol content in prostate cancer cell lines by inhibiting the activation of sterol regula
116 the effect of anti-cancer drugs in cultured cell lines by monitoring phosphatidylserine translocatio
121 ll assays using Madin-Darby canine kidney II cell line cells stably expressing specific uptake and/or
123 nduce similar transcriptional changes across cell lines, changes induced by drugs that inhibit intra-
124 viruses produced by transformed lymphocytic cell lines chronically infected with HTLV-1, particularl
125 alyzed a panel of 17 KRAS mutant lung cancer cell lines classified as K-Ras-dependent or -independent
126 ifferences in BER capacity across a panel of cell lines collected from healthy individuals, and to ge
127 pression data newly generated for 448 cancer cell lines, combined with publicly available datasets to
129 t HepAD38 cells, a widely-used HBV-inducible cell line, contain cell clones with diverse permissivene
130 for tumor tissue cores (R2 = 0.42-0.91) and cell line cores (R2 = 0.83-0.97) by quantitative immunof
132 for the FUT6 variant rs78060698 using HepG2 cell line demonstrated strong allele-specific promoter a
136 study, we examined the AR cistrome in a PCa cell line-derived CRPC model using integrated bioinforma
138 IFICANCE STATEMENT Delivery of ectopic glial cell line-derived neurotrophic factor (GDNF) promotes th
140 arboring a different oncogenic driver (K-562 cell line) did not result in selective growth inhibition
141 extracted from human lung and breast cancer cell lines, discriminating between the cancer-positive a
142 ived from HiMyc tumors (HMVP2 and derivative cell lines) displayed increased protein expression of bo
143 it most prominently reduces the workload of cell-line editing, which may be completed within 4 weeks
144 ss all major types of cancer from the Cancer Cell Line Encyclopedia, which provides genetic and expre
145 ing NAPRT levels in a BRCA2-deficient cancer cell line exacerbated DNA damage in response to chemothe
146 d to be over-expressed in all ovarian cancer cell lines examined and upregulated by mutated TP53, a g
147 e of RB-intact basal-like type breast cancer cell lines exhibited a similar phenotype following RB de
149 tate the VLP platform, we generated a stable cell line expressing high levels of ZIKV prM-E proteins
150 hat constitutively produce VLPs as well as a cell line expressing ZIKV C-prM-E proteins for RVP produ
151 te this question, we developed breast cancer cell lines expressing an inducible, constitutively activ
152 inate between normal and human breast cancer cell lines (fibrocystic and metastatic states) as well a
153 d following cisplatin- or Taxol-treatment in cell lines from both cancer types and was associated wit
155 c and 7 non-fibrotic conjunctival fibroblast cell lines from patients with and without previous glauc
156 r AsiDNA treatment was validated in 43 tumor cell lines from various tissues and 15 models of cell- a
159 When CBL was knocked down in the mutant cell line H1975 (erlotinib-resistant), it became sensiti
160 ibition of cell growth in the drug-resistant cell line H1975, without significantly affecting EGFR wi
161 ively inhibits cell growth in human leukemia cell lines harboring MLL translocations and is >40 times
163 ts with colon, breast, or ovarian cancer and cell lines harboring specific oncogenic mutations and re
164 ubcellular organelles and the lack of stable cell lines have prevented routine application of this te
166 ear cells] and epithelial and iNKT-hybridoma cell lines) have been used to determine the immunologica
168 types (the human brain capillary endothelial cell line hCMEC/D3 and human umbilical vein endothelial
169 50 = 369 muM), high efficiency against other cell lines (HCT 116 and HeLa), and possible activation b
170 ver, by utilizing the human embryonic kidney cell line HEK293T, it was possible to demonstrate that P
171 noglycosides G418 and gentamicin in hepatoma cell lines (HepG2, Hep3B and Hepa1-6) and in experimenta
173 sent study, in vitro cell models using a HCC cell line, HepG2, and human endothelial cells, HUVECs, a
176 ting cAMP signaling in the mouse hippocampal cell line HT-22 leading to an increase in CREB phosphory
177 man cells, we established several human stem cell lines: human embryonic stem cell (hESC) line carryi
179 n Caenorhabditis elegans and in chondrogenic cell lines implicated variants in genes necessary for tr
180 showed there was a tendency to describe the cell line in accordance with the description in the cite
185 (9b-9n, 10) were evaluated on various cancer cell lines including, MCF-7 breast, HL-60 leukemia, MIA
188 imary human CD4(+) T cells into immortalized cell lines indistinguishable from patient-derived ALK+ A
192 tant 4R-Tau isoform in neuroblastoma SH-SY5Y cell lines is sufficient to induce monopolar spindles.
194 q data of the human chronic myeloid leukemia cell line K562 in response to shRNA knockdown of the RNA
195 se drugs on the growth of the human basophil cell line KU812 and the human mast cell line HMC-1.
196 or inhibition of endogenous TAK1 in hepatoma cell lines leads to an upregulation of HBV replication,
200 nt at inhibiting the growth of breast cancer cell lines (MCF7, MCF7/VP16, BT474, T47D, ZR-75-1, SKBR3
201 For in vivo studies, a human breast cancer cell line (MDA-231) was implanted in five mice per group
204 By continuously exposing the gastric cancer cell line MKN45 to 5-FU for >100 passages, we establishe
205 CA11 overexpression in a t(4;14)-negative MM cell line, MM1.S, demonstrated enhanced reactive oxygen
206 overexpression, knockdown and Pak1 knockout cell line models showed that Pak1 confers protection to
208 ic and extrahepatic cholangiocarcinoma (CCA) cell lines, Mz-ChA-1, TFK-1, SG231, CCLP, HuCCT-1, and H
212 e growth of multiple RAS-mutant human cancer cell lines of diverse tissue origin by blockade of nucle
213 % growth inhibition = 0.2 mum) in almost all cell lines of the National Cancer Institute (NCI)-60 cel
214 targeting JAK for ALK- ALCL, we treated ALK- cell lines of various histological origins with JAK inhi
217 However, due to the lack of any stable flea cell line or a published flea genome sequence, little is
218 -expressing hepatocellular carcinoma (HepG2) cell line or immortalized human hepatocytes (IHH) and ac
220 and primary fibroblasts and human epithelial cell lines or primary human epithelial cells exposed to
221 xamine the effect of these haplotypes on CRC cell lines, our results suggest that inflammation and et
222 DNA damage was studied in two ovarian cancer cell lines (OVCAR3 and A2780), normal hamster ovary cont
223 n against the National Cancer Institute's 60-cell line panel and allowed us to obtain an X-ray co-cry
226 lls, was severely down-regulated in vitiligo cell line PIG3V and skin biopsy samples from vitiligo pa
227 echanistic analyses revealed that each tumor cell line presented AH1, a common endogenous retroviral
229 in a cohort of low-passage pancreatic cancer cell lines, primary patient-derived xenografts, and panc
230 ly enhanced by co-culture of leukocytes with cell lines prior to molecular and immunologic tests.
232 f TCR signaling restoration in LAT-deficient cell lines reconstituted with a synthetic LAT gene beari
233 rooted in defective glycine uptake in DLBCL cell lines, rendering them uniquely dependent upon SHMT
234 y studies in human tumors, cancer models and cell lines reveal transcriptional reprogramming that sup
235 as established in human NF1-associated MPNST cell lines (S462, T265, NSF1), and functional effects on
236 es of the National Cancer Institute (NCI)-60 cell line screen and relatively selective cytotoxicity a
237 logical investigation of 2-5 on human cancer cell lines showed enhancement of antiproliferative effec
238 ssion of GFP-tagged POMP10 in inducible RNAi cell lines shows that its mitochondrial localization dep
239 ase inhibition with CB-839 or BPTES, the RCC cell lines SN12PM-6-1 (SN12) and 786-O exhibited decreas
243 TF binding is transferable across TFs and/or cell lines suggesting there are a set of universal "rule
244 ERK phosphorylation and growth in a melanoma cell line, suggesting that it may provide a highly selec
245 KPNA4 reduces cell migration in multiple PCa cell lines, suggesting a role of KPNA4 in PCa progressio
247 ndividual haploid mouse embryonic stem (mES) cell lines targeting 16,970 genes with genetically barco
250 examine in mouse and in a mouse limb-derived cell line the dynamic events that activate and restrict
252 rve that depletion of BICD2 in the monocytic cell line THP-1 results in an induction of IFN-stimulate
253 th a low or high FcRn-expressing endothelium cell line to clearly define the FcRn involvement, intrac
255 the proteomes of 10 human pancreatic cancer cell lines to a depth of >8,700 quantified proteins.
256 rect and indirect assays in 12 breast cancer cell lines to estimate the spontaneous occurrence of sin
257 ssion levels were quantified on 20 different cell lines to identify appropriate model cells for in vi
258 ic and epigenomic study in patient-derived B-cell lines to investigate the genome-scale effects of DN
259 y driven by experimental variables including cell lines to organize and describe the diverse experime
260 provides genetic and expression data of 496 cell lines together with their response to 24 common ant
263 47-dependent phosphoproteome in the Jurkat T cell line upon treatment with T cell stimulating agents.
264 d pharmacogenomic data in cancer tissues and cell lines using a global statistical model connecting p
265 e sensitive and Pgp overexpressing resistant cell lines was found to correlate directly with an impac
266 mprehensive phosphoproteome analysis of ALCL cell lines was performed in the presence or absence of N
267 from PGE2-G response-positive and -negative cell lines was subjected to transcriptome-wide RNA seque
268 One difference between native cells and cell lines was the time absent from a fluid-phase comple
269 ically, using the RAW 264.7 mouse macrophage cell line we show that whole OSPW containing naphthenic
271 melanocytes and a highly pigmented melanoma cell line, we demonstrate that reduced expression of eit
274 h genomic analysis of colorectal cancers and cell lines, we find frequent loss of heterozygosity and
275 ce of genetic dependencies observed in human cell lines, we performed a secondary screen in a syngene
276 their human TERC knockout-derived ALT human cell lines, we show that ALT cells harbor more fragile t
277 ining lysates from an insulin-producing beta-cell line were implanted subcutaneously in autoimmune di
278 y was demonstrated in acute myeloid leukemia cell lines, where significant impairment of proliferatio
280 infected with HTLV-1, particularly the MT-2 cell line, which harbors truncated proviruses and expres
281 on; a common choice of calibrator is the 8E5 cell line, which is assumed to be stable and to contain
282 Removal of stroma enables outgrowth of PKD cell lines, which exhibit defects in PC1 expression and
283 CL2L11 or CDH9 will enhance the migration of cell lines, which provides evidence that these two genes
284 tenance under growth factor supplements into cell lines, which usually takes >6 months and results in
286 riety of TLR-transfected human embryonic 293 cell lines, while the PF-deficient mutants lacked the ab
287 ncogenic KRAS derived from a murine isogenic cell line with a coexpression network derived by integra
288 screened a library of 60,000 shRNAs using a cell line with a MeCP2 reporter on the Xi and found 30 g
289 in vitro and in vivo proliferation rates of cell lines with aberrant activation of the Hedgehog sign
290 rotein synthesis in patient-derived melanoma cell lines with acquired resistance to combined treatmen
293 AIR-overexpressing ovarian and breast cancer cell lines with PNAs decreased invasion and increased ch
294 reduced viability of two basal breast cancer cell lines with pronounced endogenous overexpression of
297 atment of MLL-fusion leukaemia cells (MV4;11 cell line) with the BET bromodomain inhibitor I-BET151 r
298 etween hiPSCs and hESCs, and clustering of 4 cell lines within each time point demonstrated that chan
299 e in vitro results were confirmed in various cell line xenograft and patient-derived xenograft mouse
300 d to extend animal survival to >90 days in a cell-line xenograft model of disseminated ovarian cancer
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