ライフサイエンスコーパス: cell membrane

1 e anchorage of the actin cytoskeleton to the cell membrane.

2 mulated on and penetrated into the bacterial cell membrane.

3 t of Wnt protein and its localization at the cell membrane.

4 olate and enrich GAGs-associated proteins on cell membrane.

5 hesion molecule (EpCAM) present on the MCF-7 cell membrane.

6 apid translocation of mTOR/LAMP2 towards the cell membrane.

7 hannels (HCs) and gap junctions (GJs) on the cell membrane.

8 plates, the extracellular matrices, and the cell membrane.

9 ACT enzyme domain directly crosses the host cell membrane.

10 entration of secretory vesicles close to the cell membrane.

11 to facilitate membrane fusion with a target cell membrane.

12 complex and stabilizes Notch1 protein at the cell membrane.

13 ident hydrophobic fusion loops into the host cell membrane.

14 lecular transport to the organization of the cell membrane.

15 nd K(+) electrochemical gradients across the cell membrane.

16 bly of a pore-forming translocon in the host cell membrane.

17 ligands bind Frizzled (FZD) receptors at the cell membrane.

18 butes critically to the stability of the red cell membrane.

19 asm, and no preferential localization at the cell membrane.

20 the increase and localization of Cers in the cell membrane.

21 r ionic interaction with anionic skin cancer cell membrane.

22 ible to overcome the challenges posed by the cell membrane.

23 through hypothesized transient breaks in the cell membrane.

24 of the FA transporters FATP1 and CD36 to the cell membrane.

25 ovides a passage for HCO3(-) flux across the cell membrane.

26 olytic instability and impermeability to the cell membrane.

27 results from MLKL-mediated disruption of the cell membrane.

28 75 TM stimulates TrkB phosphorylation at the cell membrane.

29 ational changes open a pore across the nerve cell membrane.

30 l-associated cells) expressing sst2 on their cell membrane.

31 moiety, enabling the complex to traverse the cell membrane.

32 restricted MT-mediated Cx43 delivery to the cell membrane.

33 porated into functional alpha7 nAChRs at the cell membrane.

34 ions that mimic both bacterial and mammalian cell membranes.

35 g transbilayer lipid asymmetry in eukaryotic cell membranes.

36 o kill bacteria by binding to and disrupting cell membranes.

37 cular mechanism for the control of lipids in cell membranes.

38 nst [(125)I-Tyr(4)]BBN in GRPR-positive PC-3 cell membranes.

39 target cells, where they are integrated into cell membranes.

40 driven the growth and division of primitive cell membranes.

41 ane in the furrow, and separate the daughter cell membranes.

42 molecules that interact with a wide range of cell membranes.

43 ylserine and phosphatidylethanolamine across cell membranes.

44 bbeta3 integrins and (RGD)P2Y2R expressed on cell membranes.

45 phs offer clear evidence of pores created on cell membranes.

46 ons into accessible and sequestered pools in cell membranes.

47 ostfusion structure that fuses the viral and cell membranes.

48 specially in two-dimensional systems such as cell membranes.

49 e find that recombinant ESAT-6 does not lyse cell membranes.

50 of M. tuberculosis and M. marinum lyses host cell membranes.

51 in part, through their ability to lyse host cell membranes.

52 hat catalyze the export of substrates across cell membranes.

53 otein-mediated fusion between viral and host cell membranes.

54 ic B cells take up large amounts of MOG from cell membranes.

55 proteins and from receptors in intact cancer cell membranes.

56 alf of the total phospholipids in eukaryotic cell membranes.

57 ultraviolet light, holes are drilled in the cell membranes.

58 ing the transport of water across lens fiber cell membranes.

59 red phase, which could explain their role in cell membranes.

60 aryotic cell, leading to destruction of host cell membranes.

61 e for vesicles that mimic bacterial or tumor cell membranes.

62 phospholipids for the proper functioning of cell membranes.

63 rve triggers an action potential in a muscle cell membrane, a transient increase of intracellular cal

64 In the cell membrane, a variety of fundamentally different mech

65 the extra-embryonic epithelium, mediated by cell membrane adhesion and tension.

66 Labeling the entire cell membrane allows one to demonstrate that, by contras

67 y of B cells to capture cognate antigen from cell membranes, along with small quantities of coexpress

68 ence shows that in addition to acting at the cell membrane, AMPs may act on the cell wall, inhibit pr

69 t lead to lipid and protein depletion in the cell membrane and affect cell viability.

70 itive ability and significant degradation in cell membrane and cytoplasmic structures, compared to ex

71 ved to affect the redox potential across the cell membrane and disrupt redox homeostasis, thereby inh

72 Activated MLKL translocates to the cell membrane and disrupts it, leading to loss of cellul

73 the hypothesis that interactions between the cell membrane and extracellular ice result in IIF.

74 ine-containing compounds diffuse through the cell membrane and further into acidic vesicles present i

75 s were perfused with fluorescent endothelial cell membrane and glycocalyx labels, and imaged with con

76 oside lipid GM1 is apparent in both the live-cell membrane and GPMVs.

77 signed against specific targets on the tumor cell membrane and immune cells as well as targets in the

78 This involves flow of material both in the cell membrane and in the cytoskeletal layer beneath the

79 ive feedback, combined with diffusion on the cell membrane and mechanical forces generated in the cor

80 The distance between peak cell membrane and peak glycocalyx label provided the mos

81 ctor features a biocompartment enclosed by a cell membrane and readily integrated with cells and supp

82 rs help export various substrates across the cell membrane and significantly contribute to drug resis

83 fiber optical tweezers to apply a force on a cell membrane and simultaneously measure the cellular re

84 glycomic profile of the cancerous mammalian cell membrane and successfully made a distinction betwee

85 eins that coordinate the invagination of the cell membrane and synthesis of cell wall material to cre

86 tions with their environment in their native cell membrane and the consequences on their supramolecul

87 ion, extending and inserting into the target cell membrane and then refolding into a postfusion struc

88 hich enters the cytosol directly through the cell membrane and then traffics into the nucleus, the na

89 f events culminating in fusion with the host cell membrane and transfer of genetic material for repli

90 vely interacted with and disrupted bacterial cell membranes and caused secondary gene-regulatory effe

91 via a protruding needle complex contact host cell membranes and deliver type III effector proteins.

92 d processes, especially lateral diffusion in cell membranes and geometrical constraints, considerably

93 Phospholipids occurring in cell membranes and lipoproteins are converted into oxidi

94 To fully mimic the complexity of cell membranes and optimize the efficiency of delivery v

95 s the assembly process of the lipid rafts in cell membranes and triggers orders of magnitude of sharp

96 aracteristics of tumor cells (EGFR in cancer cell membranes) and tumor microenvironments (VEGF in the

97 C (PKC), induces translocation of PKC to the cell membrane, and activates kinase activity.

98 l fusion proteins (F) insert into the target cell membrane, and form a transient intermediate that pu

99 nchored to the cell wall, extend through the cell membrane, and interact with FliG in the cytoplasmic

100 e most prominent structures in the bacterial cell membrane, and they play important functions in proc

101 d increased traction forces, vinculin at the cell membrane, and vinculin phosphorylation, suggesting

102 beta-sheets when the proteins encounter the cell membrane, and, the consensus (with a few exceptions

103 ct evidence of Wnt3A interaction with living cell membranes, and represent, to our knowledge, a new s

104 hat inserts the fusion loops into the target-cell membrane; and (iii) folding back of a cluster of ex

105 ys mediating information exchange across the cell membrane are central to a variety of biological pro

106 Interactions of soluble proteins with the cell membrane are critical within the blood coagulation

107 Cell membranes are crowded and complex environments.

108 , a condition where the usual constraints of cell membranes are overcome and cells form multinucleate

109 Additional key players are the cell membrane-associated iron transporters, particularly

110 rd and inward background currents across the cell membrane balance, determining resting membrane pote

111 ered from the mitochondria to the ER and the cell membrane becomes ruffled, as was also seen with PE

112 complement system, consisting of soluble and cell membrane-bound components of the innate immune syst

113 ents such as an oncoprotein, LMP1, into host cell membrane-bound EVs.

114 Studying the shedding of cell membrane-bound hTNF by Adam17, a known Fhl2 interac

115 topic" agent, thrombalexin (TLN), combines a cell-membrane-bound (myristoyl tail) anti-thrombin (hiru

116 hat both peptides permeabilize the bacterial cell membrane but suggested slightly different mechanism

117 eceptors revealed docking of basal bodies to cell membranes, but mature transition zones and disc str

118 Reducing the effective stiffness of the cell membrane by disrupting the actin cytoskeleton using

119 Transporters shuttle molecules across cell membranes by alternating among distinct conformatio

120 echanisms underlying the permeabilization of cell membranes by pulsed electric fields (electroporatio

121 ably because of the suppressed disruption of cell membranes by the fiber end-caps.

122 ated hydrophobic domain, mimicking bacterial cell membranes, by using dialysis and chromatography.

123 n (PrP(C)) directs it to specific regions of cell membranes called rafts.

124 HIV fusion with the cell membrane can be inhibited by blocking coreceptor bi

125 ining interactions between nanomaterials and cell membranes can expose underlying mechanisms of nanom

126 ing to lipid bilayers, a simple model of the cell membrane, can be recovered by designing cargo molec

127 osis at rat calyx of Held terminals by whole-cell membrane capacitance measurements.

128 associated with a gradual increase in whole-cell membrane capacitance.

129 Analysis is demonstrated for cell membranes, cell-derived vesicles, model membranes,

130 When n-alcohols are added to model and cell membranes, changes in membrane parameters tend to b

131 very system that combines a robust red blood cell membrane-coated nanoparticle (RBCNP) with a unique

132 Cell-membrane-coated nanoparticles have recently been st

133 which has been fabricated with a variety of cell membrane coatings, including those derived from red

134 more accessible to extended objects such as cell membranes, compared with polymer segments that are

135 is required for the conversion of the lipid cell membrane component sphingomyelin into ceramide.

136 Cell membrane composition analysis revealed the conversi

137 ble for controlling calcium dynamics are the cell membrane (comprising the surface sarcolemma and tra

138 Cell membranes contain multiple lipid and protein compon

139 Transient permeabilization of cancer cell membranes created by applying short, high-voltage p

140 Ragweed pollens did not cause significant cell membrane damage as compared to similarly sized poly

141 PpIX-SDT caused cell membrane damage prior to mitochondria damage and up

142 acteria with a mechanism of action involving cell membrane damage with leakage of intracellular compo

143 g the distance between extracellular ice and cell membrane decreased the incidence of IIF.

144 n, compared to Brownian motion, gravity, and cell membrane deformation energy.

145 ificity for small-molecule ligands in intact cell membranes, demonstrating a new approach for investi

146 We determined their effects on the cell membrane depending on their surface chemistry by mo

147 icles, made by wrapping polymeric cores with cell membrane derived from macrophages, possess an antig

148 n be readily generalized to various types of cell membrane-derived nanocarriers for broad medical app

149 mily that ensure functional receptors in the cell membrane despite prolonged agonist exposure.

150 ffect with the bisguanidine chlorhexidine on cell membrane disruption has been observed.

151 Notably, MLKL activation also causes cell membrane disruption, which allows efficient release

152 In cells, membrane domains regulate membrane dynamics and b

153 d viruses that capture a portion of the host cell membrane during budding, which then constitutes par

154 It can be exploited for further deciphering cell membrane dynamics.

155 analysis of cell migration, BM turnover and cell-membrane dynamics.

156 Vesicles, derived from cancer cell membranes encapsulating thermally oxidized PSi nano

157 expected to closely resemble those in native cell-membrane environments, although they have been diff

158 ts its potential as a versatile messenger in cell membrane events.

159 r organization of sterol-rich domains in the cell membrane, facilitates the localization of Mcp5 and

160 id polypeptide oligomers which interact with cell membranes, following a complete internalization tha

161 n the cells but need to be trafficked to the cell membrane for the channels to function.

162 lence factors, which bind to glycans on host cell membranes for internalization.

163 ncreased amounts of both Csk and PTPN22 in T cell membrane fractions and decreased association of PTP

164 Antibacterials that disrupt cell membrane function have the potential to eradicate "

165 nd reversible method is reported to engineer cell-membrane function by embedding DNA-origami nanodevi

166 Its F glycoprotein mediates virus-cell membrane fusion and is the primary target of neutra

167 mechanism, we developed a virus-free cell-to-cell membrane fusion assay to identify the minimum requi

168 ases membrane fluidity, which inhibits virus-cell membrane fusion during viral entry.

169 Virus-cell membrane fusion is an important step for a successf

170 tomegalovirus (HCMV), which are known to use cell membrane fusion rather than endocytosis to enter fi

171 ion (post-F) state at the time of virus-host cell membrane fusion.

172 tein, which carries out the process of virus-cell membrane fusion.

173 oprotein Ov8 can significantly enhance, cell-cell membrane fusion.

174 tion of cellular factors necessary for virus-cell membrane fusion.

175 ty purification processes, we extracted four cell membrane glycoproteins, CD146/melanoma cell adhesio

176 13 member 5, which transports citrate across cell membranes, halts liver cancer cell growth by alteri

177 Mammalian cell membranes have different phospholipid composition a

178 e crystals were colocated to the sections of cell membrane in close proximity to extracellular ice.

179 to localize the ECL generation on the cancer cell membrane in close proximity to the electrode surfac

180 nsient decay and quickly clears Ca under the cell membrane in diastole, preventing premature releases

181 oiety of MF6p/FhHDM-1 interact in vitro with cell membranes in hemin-preconditioned erythrocytes.

182 or individually induced permeabilization of cell membranes in the tomato fractions.

183 ance due to their preferential attack on the cell membrane, in cases where specific protein targets a

184 he effectors localize to yeast and mammalian cell membranes, including a subset of previously unchara

185 peptides, while integration into the target cell membrane increases fusion inhibitor potency.

186 d that inhibited CFTR channels remain at the cell membrane, indicative of a novel silencing mechanism

187 lly address whether distance from the target cell membrane influences the aforementioned effector mec

188 that micrometer-sized beads attached to the cell membrane integrin could trigger ICWs under mild cav

189 ed PAMAM dendrimers through determination of cell membrane integrity and comprehensive respiratory pr

190 xes, which polymerize into highly organized, cell membrane-interacting filaments.

191 structural moieties potentially involved in cell membrane interaction and damage.

192 f biomolecular binding interactions at model cell membrane interfaces.

193 of DNA-origami nanodevices can transform the cell membrane into an engineered material that can mimic

194 The cell membrane is a heterogeneously organized composite w

195 The cell membrane is a semi-fluid container that defines the

196 stablished that movement of Cl(-) across the cell membrane is coupled with cell excitability through

197 g spectra, we confirmed that the B. subtilis cell membrane is lamellar and determined that its averag

198 We further found that when cell membrane is present, the catalytic activity can be

199 ort of Gn from the Golgi complex to the host cell membrane is reduced.

200 ch actin filament polymerization deforms the cell membrane is unknown, largely due to lack of knowled

201 sight into how polycations disrupt and cross cell membranes is needed for understanding and controlli

202 When PLE is targeted to the external face of cell membranes, it controls the apparent staining of cel

203 ted from the dynamic nanoscale assemblies in cell membranes known as lipid rafts, coself-assembly of

204 Often the complexity of the cell membranes leads to anomalous diffusion, which under

205 ommonly used fluorescence probe for studying cell membrane-lipids due to its affinity toward the acyl

206 KV1.5 cell membrane localization and diphenylphosphine oxide-1

207 We report here that ESX-1-dependent cell membrane lysis is contact dependent and accompanied

208 m 1] is required for both virulence and host cell membrane lysis.

209 oreactor design is presented based on cancer cell membrane material in combination with porous silico

210 We demonstrate that cell-membrane-mimicking phosphatidylcholine (PC)-termina

211 gold nanostars, and conformal contact of the cell membrane, MTSERS permits excellent signal enhanceme

212 y an extracellular calcium influx across the cell membrane nearest to the jetting flow, either primar

213 ong-standing mystery regarding how damage to cell membranes occurs during ferroptosis, an iron-depend

214 , UV-A light and GA also cause injury to the cell membrane of E. coli O157:H7.

215 e imaging suggested that GR-3 could bind the cell membrane of hepatic tissues.

216 in B can bind to the galactose ligand on the cell membrane of host cells.

217 r, the U5 snRNP200 complex is exposed on the cell membrane of leukemic blasts.

218 a G protein-coupled receptor, located in the cell membrane of neutrophils.

219 BOMB1 specifically and strongly bound on the cell membrane of PC-3 cells displaying low internalizati

220 he host nor the guest, are able to cross the cell membrane on their own.

221 e peptide brHis2 fails to translocate across cell membranes on its own, addition of the palladium rea

222 nity and accumulation of alkane molecules on cell membranes or cellular internalization.

223 e, once a peptide has reached the cell wall, cell membrane, or its internal target, the difference in

224 T lymphocytes express not only cell membrane ORAI calcium release-activated calcium mod

225 facilitates anchoring of soluble proteins to cell membranes, our findings suggest that S-acylation an

226 cally destroy diseased cells and/or increase cell membrane permeability for drug delivery.

227 these inhibitors still suffered from too low cell membrane permeability to enter into CNS drug develo

228 Pharmacological treatment that alters cell membrane permeability to potassium affected the mai

229 id mechanical forces to transiently increase cell membrane permeability.

230 ations on a representative analogue revealed cell membrane permeabilization and depolarization in M b

231 The structural dynamics and flexibility of cell membranes play fundamental roles in the functions o

232 initiation factor 3 subunit F (eIF3F) at the cell membrane post-exercise in both groups, with the res

233 ge of hypoxia at different levels of resting cell membrane potential (Em ).

234 a wide range of hypoxia at different resting cell membrane potential (Em ).

235 in limiting depolarization of the horizontal cell membrane potential and suggest actions of these cha

236 urons had spatially uniform effects on place cell membrane potential dynamics, substantially reducing

237 (Ezh2 [enhancer of zeste homolog 2]) at the cell membrane, preventing its nuclear translocation.

238 discovered laws derive from the geometrical cell-membrane properties, such as membrane curvature, vo

239 lar C terminus regulating trafficking to the cell membrane, protein-protein interactions, and post-tr

240 Using plate-bound cell membrane proteins as targets, we detected a signifi

241 m cell-SELEX, real-time modification of live-cell membrane proteins can be achieved in one step witho

242 amics including formation of invadopodia and cell-membrane protrusions, and removal of BM.

243 h a minimal and well-controlled model of the cell membrane, provide, to our knowledge, new insights i

244 on end products (RAGE) is a highly expressed cell membrane receptor serving to anchor lung epithelia

245 gulates the expression of CD44, the major HA cell membrane receptor.

246 They bind to cell membrane receptors and are internalized.

247 rmed aminergic GPCRs) belong to the class of cell membrane receptors and share many levels of similar

248 These findings reveal a unique mechanism for cell membrane recognition and demonstrate that BoNT/DC c

249 hesion molecules, thus regulating the apical cell membrane remodeling and cytoskeletal dynamics neces

250 ansmembrane protein that plays a key role in cell membrane repair and underlies a recessive form of i

251 rk and negative mechanical feedback from the cell membrane-results in regular protrusion waves.

252 ults demonstrate the physical barrier of the cell membrane sharpens chemical gradients across the cel

253 Using cell membrane staining, we investigated the spatial dist

254 Cholesterol content alters cell membrane stiffness, and lateral lipid and protein d

255 ach for systematic in vivo investigations of cell membrane structure.

256 id membranes could also be extended to other cell membranes, such as chloroplast and mitochondrial me

257 Studies of zeta potential at the bacterial cell membrane suggested that both peptides accumulate at

258 ms both require nanosheet penetration of the cell membrane, suggesting that the enhanced antibacteria

259 e of TIRAP PBM, reducing PI interactions and cell membrane targeting.

260 These results suggest that in live secretory cells, membrane tension exerts inhibitory action on endo

261 cell and significantly higher damage to the cell membrane than GA + UV-A treatment, explaining its h

262 a multi-layered molecular scaffold along the cell membrane that may customize synaptic connectivity p

263 lly adsorb onto and/or partially insert into cell membranes, thereby amplifying interactions with sti

264 domain of PhoQ induced by a perturbation in cell membrane thickness and lateral pressure under hyper

265 ry 200 mammalian proteins is anchored to the cell membrane through a glycosylphosphatidylinositol (GP

266 tion, but then become stably attached to the cell membrane through palmitoylation of cysteine residue

267 rimary transporters that pump cations across cell membranes through the formation and breakdown of a

268 etrating peptides (CPPs) are able to bind to cell membranes, thus promoting cell internalization by a

269 Mechanistically, the diol targeted the cell membrane to alter the localization of cholesterol-b

270 ms, utilizing the proton gradient across the cell membrane to fuel the synthesis of ATP.

271 d in the trafficking of FGF receptors to the cell membrane to regulate epicardium formation.

272 olecules hold cells together but also couple cell membranes to a contractile actomyosin network, whic

273 e and technology, with examples ranging from cell membranes to liquid-crystal displays.

274 l Rho GTPases RhoA, Cdc42, and Rac1/2/3 from cell membranes to the cytosol in U251 (glioblastoma), A5

275 nsient intermediate that pulls the viral and cell membranes together as two heptad-repeat regions ref

276 easured through vinculin localization at the cell membrane, traction force microscopy, and phosphoryl

277 coded pH-sensors are widely used in studying cell membrane trafficking and membrane protein turnover

278 rboxylate, tricarboxylate or sulphate across cell membranes, typically by utilizing the preexisting N

279 d and disordered domains in mouse B lymphoma cell membranes using super-resolution fluorescence local

280 se transports Na(+) and K(+) ions across the cell membrane via an ion-binding site becoming alternati

281 unctionally couple to mediate electrosensory cell membrane voltage oscillations, which are important

282 , we demonstrate photoacoustic tomography of cell membrane voltage responses beyond the optical diffu

283 Dvl2 recruitment to the cell membrane was inhibited by Gsc in Xenopus animal cap

284 ises from the mother centriole docked to the cell membrane, was intact in the absence of C-NAP1, alth

285 ee text] and outside [Formula: see text] the cell membrane, we find signal transmission through trans

286 actions on dynamic organization in mammalian cell membranes, we have performed coarse-grained molecul

287 toward understanding lateral organization of cell membranes, we investigate the difference between na

288 lted in significant reduction in kAE1 at the cell membrane, whereas over-expression of kAE1 was accom

289 ance the electric field configuration on the cell membrane which serves as a signature characteristic

290 These events are at the cell membrane, which contributes to tighten the PI3Kalph

291 A case in point is the cell membrane, which is too small to be seen directly wi

292 This includes the use of naturally derived cell membranes, which can bestow nanocarriers with cell-

293 the complex biological functions of natural cell membranes while exhibiting physicochemical properti

294 in Cu homeostasis by pumping Cu ions across cell membranes with energy derived from ATP hydrolysis.

295 e hypothesis that enriching pancreatic islet cell membranes with EPA, thereby reducing arachidonic ac

296 lipid-modified probes can self-assemble onto cell membranes with high efficiency and stability.

297 ine serum, and an increased ability to cross cell membranes with respect to the parental drugs, expla

298 ses involve the buildup of charge across the cell membrane, with subsequent alteration of transmembra

299 sophospholipids by ACT-PLA activity into the cell membrane would form, likely in combination with mem

300 lateral organization of these domains in the cell membrane, yet the underlying mechanisms are not kno