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1 in an earlier switch and causes a reduced RM cell number.
2 m cell division to expansion to determine RM cell number.
3 mplifying cells, which together determine RM cell number.
4 orubicin was investigated by counting viable cell number.
5 l mass, cell cycle arrest, nuclear size, and cell number.
6 ng cells allowed correlating mRNA levels and cell number.
7  which encompasses the MHC locus, impacts NK cell number.
8 s are made) or counting of cell divisions or cell number.
9 ting chromogranin A-positive enteroendocrine cell number.
10 ributed by an increase in cell size, but not cell number.
11 poration, villus height and crypt depth, and cell number.
12 he HIV-1-controllers with diminished CD4(+)T-cell numbers.
13 quencing-based methods prefer native or high cell numbers.
14 d that NKG2D deficiency affects peripheral B cell numbers.
15 T cells and normal B-cell and natural killer cell numbers.
16 ent for NKG2D have a strong reduction of B1a cell numbers.
17 ensitivity of the technique in detecting low cell numbers.
18 g to an additional decrease in kidney marrow cell numbers.
19 2X7R changed linearly with concentrations or cell numbers.
20 with BCG in inducing Ag85B-specific CD4(+) T-cell numbers.
21 ic bacterial members can restore normal beta cell numbers.
22 limination of the latter decreasing CD4(+) T-cell numbers.
23 and increased Tfh cell and germinal center B-cell numbers.
24 hanced fibrosis-related genes, and increased cell numbers.
25 ased fibrous cap thickness and smooth muscle cell numbers.
26 substantial reduction in T-regulatory (Treg) cell numbers.
27 ted contraction and do not increase memory T cell numbers.
28  is associated with a striking decrease in B-cell numbers.
29 f CA1d tumors when initiated using identical cell numbers.
30 nopathy, liver dysfunction, and decreased NK cell numbers.
31 ate a subset of patients with CVID and low B-cell numbers.
32 sory hair cells has been hampered by limited cell numbers.
33 ere reductions in thymic and peripheral iNKT cell numbers.
34 ap deletion has no effect on IgM(+)IgD(lo) B cell numbers.
35 nction, promoting increases in gingival Th17 cell numbers.
36 2X7R changed linearly with concentrations or cell numbers.
37 sed marginal zone and decreased follicular B cell numbers.
38 can enhance NK cell and tumor-specific CD8 T cell numbers.
39 a common heterotic phenotype of greater leaf cell numbers.
40 ns between LLP2A signal and macrophage and T cell numbers.
41 n-presenting capacity of DCs and increased T-cell numbers.
42 n in BAL and BW samples, while requiring low cell numbers.
43 e cytokine secretion levels and regulatory T cell numbers.
44 tment can normalize hemoglobin and red blood cell numbers.
45 compartments and increases nasal CD8alpha(+) cell numbers.
46 mmune responsiveness or T reg and effector T cell numbers.
47 terial and nematode abundance, but bacterial cell numbers also declined under warming, demonstrating
48 ly in T cells led to a strong reduction in T cell number and a shift toward the effector/memory pheno
49 eading to an increase of both GLP-1-positive cell number and basal and stimulated GLP-1 plasma levels
50 d that short-term CR increased the satellite cell number and collagen VI content of muscle, but resul
51 orrelated with antitumor efficacy, whereas T cell number and cytokine profile were not.
52 lin-28-associated defects in intestinal stem cell number and division pattern.
53  directly restricted the natural killer (NK) cell number and effector function.
54                                       Leydig cell number and function decline as men age, and low tes
55 an provide high-throughput quantification of cell number and function in BAL and BW samples, while re
56 as associated with significantly improved NK-cell number and function, lower viral infections, and lo
57 ere of higher quality than C-IVF in terms of cell number and hatching ability.
58 ire an optimal size that is defined by total cell number and individual cellular dimensions.
59 lerance, and a substantial reduction on beta cell number and mass.
60 -1 with an antibody increased KLRG1(+) ILC-2 cell number and reduced disease burden.
61 a reveal LEF1 as a central regulator of iNKT cell number and Th2-type effector differentiation.
62 evelopment much evidence indicates that both cell number and the cell fates generated by each neurobl
63 ted immunity requires a massive expansion in cell number and the development of long-lived memory cel
64 have analyzed the relationship between ovary cell number and the final size of ovaries and berry frui
65  An attractive theory is that a loss in stem cell number and/or activity over time causes this declin
66  of severe asthma, as well as on airway mast-cell numbers and activation in patients with severe asth
67 4-day Ang II infusion increased gammadelta T-cell numbers and activation in the spleen of wild-type m
68 king PKC-theta had reduced ILC2 numbers, TH2 cell numbers and activation, airway hyperresponsiveness,
69 ses that together closely mimicked declining cell numbers and cell cycles, and by small interfering R
70 to LNG-treated mice at 1 dpi restored lung T cell numbers and chlamydial burden at 12 dpi to levels s
71 ia-antigen-loaded DCs increased de novo Treg-cell numbers and dampened effector T-cell expansion and
72 ociated with the decrease in iNKT1 and iNKT2 cell numbers and decrease in survival, related to change
73                  SH also increased microglia cell numbers and decreased 5-HT immunoreactivity in the
74 cells resulted in decreased peak donor CD8 T cell numbers and decreased CTL effector function due to
75 evealed a positive association between CD8 T cell numbers and decreased proinflammatory function of m
76 ncy in T cells led to decreased peripheral T cell numbers and defective homeostatic proliferation, bu
77 cells corresponded to diminished tissue mast cell numbers and expression of mast cell proteases.
78 is a positive relationship between apoptotic cell numbers and fluorescence intensities.
79 c deletion of CD28 caused a reduction in TFR cell numbers and function, which resulted in increased g
80 lear cells was assayed, as were regulatory T-cell numbers and function.
81 nce, but increased IL-22 in vivo decreased T cell numbers and functions in the liver and lymphoid tis
82 ty as demonstrated by augmented CD4 TFH/GC B cell numbers and hastened islet allograft rejection in n
83  during T-cell priming, whereas allogeneic T-cell numbers and homing in lymphoid and GVHD target orga
84  cells resulted in a marked reduction in TFH cell numbers and IgE antibody levels, but type 2 cytokin
85 f GABA catabolism or GABA uptake reduced NG2 cell numbers and increased the formation of mature oligo
86 recurrent infections, despite normal T and B cell numbers and intact in vitro lymphocyte function.
87 evelopment of septic shock by maintaining NK cell numbers and integrity.
88                                          TH2 cell numbers and levels of their cytokines, IL-4 and IL-
89 e data suggest that tissue resident effector cell numbers and low FcgammaR expression may limit the p
90  the alteration of beta-cell identity, islet cell numbers and morphology, and gene expression by disr
91         This review aims to compare cortical cell numbers and neuronal cell types to the elaboration
92 tion of BAFFR-Fc in mice reduced pulmonary B-cell numbers and prevented CS-induced formation of lymph
93 d on tissue culture-treated surfaces, by 4 d cell numbers and proliferation rates were significantly
94 mTORC1 signaling in tendons increased tendon cell numbers and proliferation.
95 about how progenitor cell and differentiated cell numbers and proportions are maintained.
96 ants' blood samples were also analyzed for B-cell numbers and proportions of CD5(+) and CD27(+) B cel
97 g RNA reduced esophageal eosinophil and mast cell numbers and protected against esophageal circumfere
98                                       Goblet cell numbers and resistin-like molecule beta (RELM-beta)
99 8(EGFP/EGFP) retina as determined by VSX2(+) cell numbers and retinal morphology at postnatal day 6.
100 ic HLA multimers to enumerate CMV-specific T-cell numbers and select cells to assess chimerism status
101 ound that Neu5Gc exposure reduced IL-17(+) T-cell numbers and supported differentiation of regulatory
102 tion between absolute natural killer T (NKT) cell numbers and the subsequent development of MODS.
103  inhalation markedly increased airway goblet cell numbers and thickness of the epithelium and subepit
104 sion, a significant increase in FOXP3 + Treg cell numbers and tumor-specific T cell responses were ob
105 provement, suggesting that increases in Treg cell numbers and/or proportions are not driving the mech
106                     Regulatory T cell (T reg cell) numbers and activities are tightly calibrated to m
107      All NK expansions achieved the required cell number, and 11 of 13 patients enrolled received all
108  increases in bone marrow cellularity, CD34+ cell number, and frequency of early hematopoietic progen
109 ormal brain growth trajectory by controlling cell number, and imbalance in this relationship can resu
110 on in islet density, decreased relative beta-cell number, and presence of amyloid deposits.
111 mperature variability affects soil bacterial cell numbers, and abundance and traits of soil microfaun
112              After challenge, symptoms, Treg cell numbers, and forkhead box protein 3 (Foxp3), TH2 an
113 n TIL cultures was associated with reduced T cell numbers, and further functional studies demonstrate
114 ymphocytes, decreased plasmacytoid dendritic cell numbers, and increased representation of activated
115 D4(+) T-cell frequencies, decreased CD8(+) T-cell numbers, and resolution of CD8(+) T-cell alveolitis
116 cant increases in splenic and bone marrow B1 cell numbers, and that the B1 progenitor cell pool is in
117 cal adhesion kinase activation and satellite cell number are elevated in muscles undergoing massage d
118 etween visual field sensitivity and ganglion cell number are reviewed.
119                      Methods for quantifying cell numbers are already available (e.g., fluorescence i
120 s in inflammation, coagulation, and CD8(+) T-cell numbers are associated with an elevated cardiovascu
121 ulations, and aberrations in functional stem cell numbers are associated with malignancies and aging.
122                  We previously found that NK cell numbers are decreased in Stat5a-Stat5b tetramer-def
123                           Although higher B1 cell numbers are discussed to be associated with autoimm
124           Although total CD4(+)FOXP3(+) Treg cell numbers are reduced, frequencies are maintained in
125 ive capacity of a muscle even when satellite cell numbers are reduced.
126             In this model, circulating tumor cell numbers are significantly reduced in mice treated w
127  parasegment, concomitant with a doubling of cell number as the tissue elongates.
128 tion of CD1d and show increased hepatic iNKT cell numbers as a consequence of altered iNKT cell apopt
129  coupled with myocyte hyperplasia (increased cell number), as observed in Mybpc(t/t) mice.
130 uced 5-bromo-2'-deoxyuridine (BrdU)-positive cell numbers at the injected site on day 7 and the expre
131  model, we show that despite reduced total B cell numbers, B cell development in these mice occurs no
132                        Increased initial ECT cell number beyond 6 M per construct resulted in reduced
133 spensable for the attainment of final Leydig cell number but is essential for Leydig cell maturation
134 bone marrow (BM) c-Kit(+)Sca1(+)Lin(-) (KSL) cell number but reduced BM KLCD150(+) and KLCD150(+)CD48
135 during repair initially increases epithelial cell number but, following the shedding phase, normal de
136 BB-Cl-amidine, there was a decrease in total cell numbers but an increase in the proportion of Th2 ce
137  not merely extruded to maintain homeostatic cell numbers, but are also sampled by a single subset of
138                         The increase in Treg cell numbers, but not their differentiation toward an ef
139 ed IL-2 signals increase peak effector CD8 T cell numbers, but only early IL-2 signals enhance memory
140  and miR-145 transfection decreased cervical cell number by increasing apoptosis and decreasing cell
141 r the bone loss as well as the increase in B cell number caused by estrogen deficiency.
142    Often, as total cell number changes, stem cell number changes proportionally in a phenomenon calle
143                              Often, as total cell number changes, stem cell number changes proportion
144                                However, Treg cell numbers collapsed after LCMV inoculation.
145 LA-4 blockade resulted in lower memory CD8 T cell numbers compared with the DC+early IL-2 treatment g
146 ant decrease in absolute live or total CLL B-cell numbers, confirming that trogocytosis occurs, rathe
147 types included smaller eyes and reduced hair cell numbers, consistent with the optic atrophy and hear
148                       We focused on amacrine cell number control, identifying three downstream Pten e
149 ed Pten downstream of TgfbetaRII in amacrine cell number control.
150 ighting its diverse actions as a mediator of cell number control.
151  all mature B-cell subsets, but follicular B-cell numbers could be largely rescued by ectopic express
152 s, bronchoalveolar lavage (BAL) inflammatory cell number, cytokine concentration, protein concentrati
153 ids varied by several structural parameters: cell number, diameter and morphology.
154 However, the change in Ki-67-positive ductal cell number did not differ significantly between the EXE
155 ckcre(tg) Grb2-deficient mice show reduced T cell numbers due to impaired negative and positive selec
156  its ligand, SDF-1 (CXCL12), decreased THP-1 cell numbers due to reduced cell proliferation.
157                    Some clusters increase in cell number during late larval stages, whereas others do
158 ox4 is essential for the maintenance of beta-cell number during the development of type 2 diabetes.
159 e beneficial effect of membrane TNF on T reg cell numbers during chronic inflammation, but in additio
160 ire months of culture to generate sufficient cell numbers for feasibility studies in a lab setting an
161 in terms of efficiency and ensuring adequate cell numbers for quantification.
162  as well as the tissue requirements (minimal cell number) for the generation of extrasystoles, and th
163 , CD4(+) naive T-lymphocyte, CD19(+), and NK-cell numbers from pretransplant until 15 years posttrans
164             Finally, early changes in immune cell numbers had a significant correlation with disease
165 scussed here include choosing of appropriate cell numbers, handling of the cells, selection of recipi
166 the OD value obtained is proportional to the cell number, i.e. the concentration of the sample.
167 luates the impact of intravascular bacterial cell numbers (ie, the level of bacteremia), in patients
168 ximal to the heart and increased endothelial cell number in arterial segments distal to the heart.
169 d migration results in decreased endothelial cell number in arterial segments proximal to the heart a
170 gly suggest that an early deficiency in beta-cell number in infants with CF may contribute to the dev
171 constitute approximately 10-20% of the total cell number in most CNS regions, a smaller fraction of t
172  development, which affect the terminal seam cell number in opposing directions.
173 these were associated with decreased Sertoli cell number in Ppard(+/+) mice.
174 veals mechanisms that precisely control stem cell number in response to tissue needs.
175 h an exogenous signal peptide increased beta-cell number in the absence of overnutrition.
176 Glut1 and Mcl-1 levels, glucose uptake and B cell number in the absence of TRAF3 were all dependent u
177  associated with embryo quality as the total cell number in the resulting morulae and blastocysts pos
178 hat Pten is a critical regulator of amacrine cell number in the retina, acting via multiple downstrea
179 ation, whereas RGF1 affected circumferential cell number in the root meristem.
180 o apoptosis, the overall maintenance of beta-cell number in those animals was sustained likely due to
181 -lysis protocol allowing acquisition of high cell numbers in 377 bone marrow follow-up samples of 178
182 novel hypothesis to explain how differential cell numbers in a bilayered epithelium can lead to shape
183 ncy of key phenotypic traits such as correct cell numbers in a certain tissue.
184 flammation/gliosis and increased neural stem cell numbers in areas of tissue injury.
185 n in the ischemic heart, and reduced myeloid cell numbers in atherosclerotic plaques.
186 ificantly increased median B cell, but not T cell numbers in both cohorts, with a trend for increased
187 ed to a marked reduction of eosinophil and T cell numbers in bronchoalveolar lavage fluid compared wi
188 Ibrutinib markedly increased CD4+ and CD8+ T cell numbers in CLL patients.
189  accompanied by significantly attenuated niT cell numbers in draining lymph nodes.
190                      Exponential increase of cell numbers in early embryos requires large amounts of
191               In this study, we found that T cell numbers in Grb2(fl/fl) CD4cre(tg) mice were normal
192 stored allergic diarrhea and intestinal mast cell numbers in IL-10(-/-) mice, suggesting that the reg
193                         The collapse of Treg cell numbers in LCMV-triggered perforin-deficient, but n
194  enhanced CD4 TFH and germinal center (GC) B cell numbers in naive mice and hastened islet allograft
195 nalyzed various molecular markers of T and B cell numbers in neonatal dried blood spots of 99 childre
196 on of Runx1 to control lineage decisions and cell numbers in progenitors, our study also revealed a c
197 C-mediated expansion of CD24(+)CD38(hi) Breg cell numbers in SLE was associated with altered STAT1 an
198 oved lung compliance, and increased CD8(+) T cell numbers in the airways.
199 e mice, there was a significant defect in NK cell numbers in the bone marrow and peripheral organs de
200 loss and osteoclast numbers by reducing Th17 cell numbers in the bone marrow and reducing the product
201 es, dibenzazepine administration increased L cell numbers in the intestine, improved the early insuli
202 ults in dramatically decreased CD4 and CD8 T-cell numbers in the lamina propria of both small and lar
203 ion, and an increase in intraepithelial mast cell numbers in the lung.
204  the bone marrow and an increase in normal B-cell numbers in the peripheral blood.
205 ads to splenic atrophy and contraction of NK cell numbers in the periphery through a modulated expres
206  of Runx1 leads to a severe decrease in iNKT cell numbers in the thymus, spleen and liver.
207   Surprisingly, LRBA limits immunoregulatory cell numbers in tissues where GvHD is primed or initiate
208 ether STAT6 signaling regulates gammadelta17 cell numbers in vivo, we used a model of Klebsiella pneu
209 , cytokine profiles and Th-1, Th-2 and Th-17 cells numbers in each mating type treated mice showed th
210                                IgE(+) plasma cell numbers, in particular, increased after FAS inactiv
211            There are several ways to control cell number, including readouts of organ function (e.g.,
212 n proliferate but it is not known if crystal cell numbers increase by self-renewal or by de novo diff
213 ion with vaccinia virus, dermal gammadelta T cell numbers increased 10-fold in the infected ear and r
214  FOXP3(lo/-)CD4 T cells while FOXP3(hi)CD4 T cell numbers increased.
215                              The decrease in cell number is due to a combined decrease in proliferati
216 ver, they suggest that estrogen control of B cell number is indirect via osteocytes and that the incr
217                                The decreased cell number is not due to defective homeostasis or incre
218      The latter applies to the retina, where cell number is regulated by negative feedback signals, w
219    Although the age-related fall in CD8(+) T-cell numbers is well established, neither the underlying
220 ation activity and severely reduced mature B cell numbers, Lig4(R278H/R278H) (Lig4(R/R)) mice exhibit
221 rowth occurs predominately by an increase in cell number; little is known about growth mechanisms lat
222                       HDC(+)CD11b(+) myeloid cell numbers markedly increased in the injured hearts, a
223  could be shown that even very low bacterial cell numbers (minimum 500 cell ml(-1)) could be detected
224             Furthermore, new dentate granule cell number, morphology and excitatory synaptic inputs a
225 m more than one founder cell and the minimal cell number needed for successful colony formation.
226 scriptional defects were only uncovered when cell number-normalized approaches were used, and correla
227 se treatments led to an increase in absolute cell number of more than 10(12)-fold.
228                             Reduced absolute cell numbers of Tconvs after inhibitor treatment in vivo
229 lation between responsiveness to stimuli and cell numbers of the human immune system.
230      The CLAVATA pathway that regulates stem cell numbers of the shoot apical meristem has exclusivel
231                                Despite equal cell numbers on both sides, neuron identities and pathwa
232         AEA caused a significant decrease in cell number only at concentrations above 1000 nM (mean 2
233  receptor alpha from B cells did not alter B cell number or bone mass and did not alter the response
234 mor efficacy, without affecting responding T cell number or cytokine profile.
235 ity structure can be analyzed by quantifying cell numbers or by quantifying biomass for individual po
236 ated T-cell expansions do not impair naive T-cell numbers or maintenance of protective responses agai
237 1 Ab treatment did not alter immune effector cell numbers or myeloid cell activation.
238  zinc finger transgene does not restore iNKT cell numbers or the block in positive selection into the
239 ts, with significant differences in CLA(+) T-cell numbers (P < .01).
240 natal insulin secretion correlated with beta cell numbers (P = 0.03).
241  that modulating the bulk cell density (BCD: cell number per culture volume) deterministically alters
242 lesion macrophage-positive area and CD4(+) T-cell number per lesion area, but reduced lesion expressi
243  p<0.001; rs(51)=0.744, p<0.001) between the cell number per well and the number of detected referenc
244                                              Cell number plasticity is coupled to circuitry in the ne
245 g BDNF generated increased daughter neuronal cell numbers post-differentiation, with accelerated matu
246                                       Sickle cell numbers ranged from 631 (4.6%) for trait and 23 (0.
247       We recently showed that blood CD4(+) T-cell numbers rapidly increase after dUCBT, and early CD4
248 icantly reduced leukemic stem and progenitor cell numbers, reduced regeneration of leukemic long-term
249 d nod positionally and found that it encodes CELL NUMBER REGULATOR13 (CNR13), the maize MID-COMPLEMEN
250 s, but showed no differences in regulatory T-cell numbers relative to patients without IRAEs.
251  considerable virus spread, and the absolute cell numbers remained low.
252 aseline 24 hours after HC infusion, while NK cell numbers remained stable.
253 ibroblasts (CFU-Fs) on plastic and the large cell numbers required for transplantation.
254   We hypothesized that this reduction in new cell numbers resulted from impaired proliferation, which
255               Dibenzazepine also increased K cell numbers, resulting in increased gastric inhibitory
256 l stainings were analyzed for the respective cell numbers separately for tumor area, infiltrative mar
257                    Notch2(+/-)/NOD have MZ B cell numbers similar to those of wild-type C57BL/6, yet
258  volumetric differences represent changes in cell number, size, and/or connectivity, which may denote
259               Experimentally reducing Ocn(+) cell numbers suppresses the neutrophil response and lung
260                                    Dendritic cell numbers, T cell activation, and infiltration of CD8
261 ost CNS regions, a smaller fraction of total cell number than previously estimated in the normal adul
262 cytes constitute a smaller fraction of total cell number than previously estimated in the normal adul
263 henotype positively correlate with Satellite cell number, the resident stem cells of skeletal muscle.
264 pt organoid proliferation and increased stem cell numbers through pSTAT3 activation in Paneth cells.
265 y developing embryos refocus from increasing cell number to elaboration of the body plan.
266 leading to reductions in pathologic DC and T-cell numbers to nonlesional levels; and (3) inhibition o
267 tionship of these changes, especially in NKT cell numbers, to patient outcomes such as MODS warrants
268 s a homeostatic sensor to control epithelial cell numbers, triggering extrusion and apoptosis in crow
269 force generation and insufficient epithelial cell number underlie the branching defects.
270  lymph nodes and induced an increase in Treg cell numbers upon exposure to IR, but Cdkn1a(-/-) LCs di
271 x (bHLH) transcription factor, increase seam cell number variability.
272 as solar irradiation is able to reduce total cell numbers, viable E. coli remained and expressed gene
273                     However, cervical CD4+ T-cell number was associated with HSV-2 infection and a di
274                                CD4(+)CD25(+) cell number was negatively associated with blood urea ni
275                    However, a rebound in the cell number was observed after the prolonged exposure ex
276 gene-reporter probe systems for imaging of T cell number was performed, and the hNET/(18)F-MFBG PET r
277                                  Endothelial cell number was reduced in WT-diabetic hearts compared w
278                     This enhancement of Th17 cell number was specifically observed for the memory CD4
279                   Increase in KLRG1(+) ILC-2 cell numbers was attributed to an intrinsic defect in PD
280 Th) T cell activity, and natural killer (NK) cell number were measured by flow cytometry.
281                                              Cell numbers were adequate to perform flow cytometric an
282  in whom bronchoalveolar lavage regulatory T-cell numbers were also reduced.
283                                         Mast cell numbers were associated with airway smooth muscle p
284 pecific CD8(+) T cells, but overall CD8(+) T cell numbers were either unaffected or only mildly incre
285                   Naive and central memory T-cell numbers were not affected, nor were anti-tetanus an
286                        Decreases in DC and T-cell numbers were observed after weeks 1 and 2, respecti
287                            Moreover low Treg cell numbers were observed in untreated patients experie
288 c cells decreased in blood, whereas NK and T cell numbers were only marginally altered during the cou
289  cells was still abrogated, but follicular B-cell numbers were only mildly affected.
290                   BAM removal rates and MSH1 cell numbers were recorded during operation and assessed
291 onditional deletion of the Rictor gene, iNKT cell numbers were reduced in the thymus and periphery.
292                                         Beta cell numbers were significantly elevated in prenatally a
293 activated Tregs led to a 90% reduction in NK cell numbers when added at the time of commitment to the
294 l thymus recovery and boosts donor-derived T cell numbers, which correlates with increased adhesion m
295 is also likely due to an overall increase in cell numbers, which would allow for processing of a wide
296 phragm fibroblasts at 14 wk showed a similar cell number with a similar level of collagen and profibr
297 st, the rate of decline in thymic epithelial cell numbers with age was radiation-sensitive only in ma
298 teristic shift in dark zone and light zone B cell numbers, with an increase of B cells in the dark zo
299 significant reduction in monocyte/macrophage cell numbers within PBMCs in a dose-dependent manner.
300 CD45(+), CD3(+), CD4(+), CD8(+), and CD20(+) cell numbers within the insulitis (r = 0.53-0.73, P = 0.

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