ライフサイエンスコーパス: cell population

1 supervised stratification of a heterogeneous cell population.

2 ation subsets rather than the full claustral cell population.

3 e afferent connectivity of this diencephalic cell population.

4 specification program within the multipotent cell population.

5 ng hormonal-induced expansion of the mammary cell population.

6 MSCs) are a therapeutically relevant primary cell population.

7 ce/survival of the mature naive peripheral B cell population.

8 onal repair derived from a therapeutic donor cell population.

9 major cell types of a VIP-ires-Cre amacrine cell population.

10 type, and function from the majority (B-2) B cell population.

11 on start sites of germline genes in the stem cell population.

12 association with significantly decreased B1a cell population.

13 n, with expansion of the regulatory T (Treg) cell population.

14 hered from a single living cell other than a cell population.

15 ctly and through an intermediary nonlymphoid cell population.

16 hanced our understanding of this enigmatic B cell population.

17 hemichannel activity specifically in a glial cell population.

18 for cell types comprising >/= 20% of a mixed cell population.

19 trolling the make-up of the pluripotent stem cell population.

20 ection for a CD133(+) endothelial progenitor cell population.

21 atory synaptic inputs that differ among this cell population.

22 ted cells, consistent with a progenitor/stem cell population.

23 hy skin samples, followed by RNA-seq of each cell population.

24 of the proliferation dynamics of the cancer cell population.

25 mmune infiltration by macrophages or T- or B-cell populations.

26 xtent of internalization of nanoparticles in cell populations.

27 e cytokine expression levels within infected cell populations.

28 the differential growth of the corresponding cell populations.

29 c heterogeneity is widely observed in cancer cell populations.

30 olar type II (AECII) cells in dispersed lung cell populations.

31 ge of ECM densities, composition and stromal cell populations.

32 x, and the presence of HCV-specific CD4(+) T cell populations.

33 will require suppression of these resident T cell populations.

34 support both mature and immature GBM tumour cell populations.

35 he CD34+, LGR5+, and LGR6+ keratinocyte stem cell populations.

36 ically target these interactions in discrete cell populations.

37 to infect a variety of immune and nonimmune cell populations.

38 nly specific subsets of tumor-infiltrating T cell populations.

39 or marker differences between and/or within cell populations.

40 identifying and targeting recalcitrant stem cell populations.

41 VL sequences from sorted naive and memory B cell populations.

42 ly or by targeting non-T cell or non-myeloid cell populations.

43 ays and cellular functions in the respective cell populations.

44 r EpCAM) or size to separate them from blood cell populations.

45 the expansion of protective natural killer T-cell populations.

46 onal transcriptome analysis of heterogeneous cell populations.

47 (15 to 21 weeks postconception) using clonal cell populations.

48 microarray and BeadChip analyses of the same cell populations.

49 titative, and dynamic molecular maps in live cell populations.

50 sitivity and application when examining rare cell populations.

51 and isolating functional beta cells in mixed cell populations.

52 e, identified from DNAm measures of purified cell populations.

53 nal features of human Th17, Th1, and ex-Th17 cell populations.

54 differentiation of T follicular helper (TFH) cell populations.

55 fect the potential for repair by therapeutic cell populations.

56 (GPI-negative) HSPC-derived peripheral blood cell populations.

57 logical pathways and the isolation of target cell populations.

58 roliferation, migration or death of distinct cell populations.

59 estigation of chromatin architecture in rare cell populations.

60 are likely to synergize to maintain diploid cell populations.

61 ic damage with dramatic reduction of splenic cell populations.

62 munohistochemical staining in the respective cell populations.

63 messenger RNA expression from isolated liver cell populations.

64 tions from difficult-to-characterize or rare cell populations.

65 ntaneous PTL harbored functionally altered B cell populations.

66 ng heterogeneity in gene expression in large cell populations.

67 evident within the Lrig1+ keratinocyte stem cell population (69 vs. 55%, P < 0.01, n = 7), and not i

68 the Krt15 promoter marks a long-lived basal cell population able to self-renew, proliferate, and gen

69 utation in Cul9 (Deltap53) increases S-phase cell population, accumulates DNA damage during DNA repli

70 pment, tissue homeostasis and disease is how cell populations adapt to sensory inputs.

71 glass surface for stem cell maintenance and cell population analysis (3 d).

72 -resistant SCs that are not apparent through cell-population analysis.

73 hly expressed in MaSC-enriched mammary basal cell population and in mammary tumors, and is regulated

74 levated the intrahepatic regulatory T (Treg) cell population and increased the expression of transfor

75 a considerable heterogeneity of the CML stem cell population and propose a Lin(-)CD34(+)CD38(-/low)CD

76 cells results in the gradual loss of a stem cell population and severe differentiation defects, lead

77 nalized transcriptional programs in the stem cell population and subsequently promote cell-type diver

78 The identity of the cell population and the signaling pathways involved in t

79 th autoantigen and dexamethasone increased B-cell populations and antibody production, signifying an

80 location is seen not only within individual cell populations and between cell types, but also betwee

81 Dual RNA sequencing of individual host cell populations and C. albicans revealed that dermal in

82 rapid detection of iSTOP-mediated editing in cell populations and clones.

83 specific ablation of Bmp6 in different liver cell populations and evaluated their iron phenotype.

84 ly automates the classification of canonical cell populations and highlights novel cell types in mass

85 tion in different biological states, both in cell populations and in single cells.

86 th expand pre-existing neoantigen-specific T-cell populations and induce a broader repertoire of new

87 We further evaluate these barcodes in cell populations and show that they can be used to recor

88 fficacy of a new approach to classify single cell populations and subpopulations using SIMS profiling

89 ts, including similarity between Th1-Th2-Tfh cell populations and Th17 cells, as well as similarity o

90 ut epithelium by promoting goblet and Paneth cells population and reinstating the E-cadherin and N-Ca

91 a decrease in the neoplastic neuroendocrine cell population, and impaired PanIN progression to tumor

92 ely primitive skeletogenic potential of this cell population, and point to a neural crest origin of d

93 transcriptomic and metabolomics signatures, cell populations, and cytokine levels, and identifies im

94 Tag-seq of microdissected tissue, RNA-seq of cell populations, and single cells.

95 Alterations of the B cell population are not correlated with production of ne

96 Several immune cell populations are involved in cartilage damage, bone

97 cient transduction across specific organs or cell populations are needed.

98 iminished neurogenesis in the MCT8-deficient cell population as well as aberrant migration of both ea

99 ct from the precursors of circulating memory cell populations at the levels of gene expression and ch

100 staining of the viral HA revealed that most cell populations become infected, most prominently CD45(

101 The ES cell population behaves asynchronously.

102 tracked to CD34(+) hematopoietic progenitor cell populations, being further enriched in B and NK cel

103 pment and maintenance of progenitor and stem cell populations, but has also been proposed in vitro as

104 has transformed our understanding of complex cell populations, but it does not provide phenotypic inf

105 vestigated the regenerative capacity of this cell population by comparing the responses of early post

106 th moderate, discrete activation of distinct cell populations by fear or safety cues and robust, glob

107 r, and provide a new strategy on controlling cell populations by manipulating noise strength.

108 In this study, we examined CD3(+)CD4(+) T cell populations by single-cell mass cytometry.

109 come more complex, detection of minor immune cell populations by traditional gating using biaxial plo

110 This cell population can be successfully differentiated from

111 e novel evidence that a specific host immune cell population can block the potential for functional r

112 In vitro expanded cell populations can contribute to bioengineered tooth f

113 le-cell RNA sequencing data of heterogeneous cell populations, cell cycle stage of individual cells w

114 duced IL-22 production from a mixed T helper cell population comprised of Th1, Th17, and Th22 cells,

115 man breast adipose tissue is a heterogeneous cell population consisting of mature white adipocytes, m

116 an standard gene-editing methods, and enrich cell populations containing multiplexed precise edits up

117 xic drugs or epigenetic modifiers, NE and ML cell populations converged toward the hybrid state, sugg

118 t increased expression of Bcl-6 in CD4(+) Th cell populations correlated with enhanced enrichment of

119 in our understanding of the nature of these cell populations, coupled with a limited ability to ther

120 primary and metastatic cells as two distinct cell populations defined by differential expression of 4

121 gations revealed an increase in the G0 phase cell population depicting that majority of cells were in

122 e targeted to enhance production of specific cell populations derived from human pluripotent stem cel

123 e YFP expression in all neural crest-derived cell populations despite loss of Wnt1 expression.

124 In particular, the human progenitor cell population differentiated, matured, and integrated

125 ealed transcriptional profiles of individual cell populations distinct from bulk skin, most strikingl

126 We also observed changes in CD4+ T-cell population diversity and clonal viral sequence expa

127 expansion of pathogenic, myelin-specific Th1 cell populations drives active disease; selectively targ

128 Here we characterise the endometrial CD8-T cell population during the embryonic window of implantat

129 transcriptional resource of multiple cardiac cell populations during cardiac development, repair, and

130 RNAs control the function and homeostasis of cell populations during immune responses, emphasizing th

131 tion of doxorubicin therapy shape subsequent cell population dynamics.

132 tion with single cell arraying of the target cell population, enabling direct on-chip tumor cell iden

133 nated with projection- and behavior-specific cell populations, enabling adaptive tuning of emotional

134 Zika targets cerebral neural precursors, a cell population essential for cortical development, but

135 Consistent with a defect in the AT2 stem cell population, Etv5 deficiency markedly reduced recove

136 nial neural crest or from multiple embryonic cell populations evolving most quickly and into a greate

137 -lapse analyses to reveal that mycobacterial cell populations exhibit heterogeneity in their DNA repl

138 However, ostensibly homogeneous cell populations exhibit large clonal variance that can

139 MPN mice harbor an expanded Thy1(+)LSK stem cell population exhibiting increased cell cycling and a

140 , we identify a quiescent mammary epithelial cell population expressing high levels of Bcl11b and loc

141 ere detected in both epithelial and lymphoid cell populations expressing CD155 in the tonsil and inte

142 ion (immunohistochemistry), and infiltrating cell populations (flow cytometry).

143 , endocardially-derived angiogenic precursor cell population for coronary artery formation in mice an

144 at the same three key combinations of immune cell population frequencies can define an individual's i

145 Our analyses of various measured immune cell population frequencies in healthy humans and their

146 col to consistently generate 3 distinct stem cell populations from a single human heart biopsy.

147 of a protocol for isolation of multiple stem cell populations from a single myocardial tissue sample

148 escribed herein enables the analysis of rare cell populations from noninvasive serial tissue sampling

149 dysfunctional T cells within heterogeneous T cell populations from tumours in mice; these surface mar

150 cell niches in sorted bone marrow and rectal cell populations further supported this model and reveal

151 ntracellular abundance of eIF4G and rates of cell population growth and global mRNA translation, with

152 studies demonstrated that the original Gli1+ cell population had the capacity to heal immature enthes

153 Yeast cell populations harboring the same defined aneuploidy e

154 on of single-cell genome sequencing to large cell populations has been hindered by technical challeng

155 resolve cell-associated (metal) NPs in bulk cell populations, however, such analysis at single cell

156 The cell population identified here may serve as a promising

157 cells are homologous to the Vgamma9Vdelta2 T cell population identified in human psoriatic plaques.

158 er retina that replenishes the local myeloid cell population in a CCR2-regulated manner.

159 we identify a highly tumorigenic cancer stem cell population in a mouse model of transitional epithel

160 T lymphocytes constitute a major effector cell population in autoimmune type 1 diabetes.

161 , and which conjointly identify this retinal cell population in its entirety when using antibodies to

162 entiated, non-dividing esophageal epithelial cell population in patients with active EoE.

163 show that Troy marks a renal stem/progenitor cell population in the developing kidney that in adult k

164 survival (RCS), i.e. the ratio of normalized cell population in the irradiated samples to that of the

165 polydendrocytes, which are a resident glial cell population in the mature mammalian central nervous

166 n, we have described a long-lived progenitor cell population in the mouse esophageal epithelium that

167 nuclear layers and within the spindle-shaped cell population in the vanguard in Case 1.

168 sting up-regulation of EP4 in an alternative cell population in these mice.

169 d mononuclear cells represent a key effector cell population in this model of virus-induced inflammat

170 ckouts showed that 2B4 functions on CD4(+) T cell populations in a cell-intrinsic manner and modulate

171 ant NKT), and mucosal-associated invariant T cell populations in a dose-dependent manner, resulting i

172 everal prostate cancer (PCa) stem/progenitor cell populations in both xenograft and primary patient t

173 Runx3 was required to establish TRM cell populations in diverse tissue environments, and sup

174 of IFN-gamma and IL-17A-producing effector T cell populations in female SjS(S) mice compared to male

175 recruitment and differentiation of different cell populations in granulomas would be a useful researc

176 stinct pluripotent stem cells in mesenchymal cell populations in humans.

177 exities in the involvement and regulation of cell populations in IgG-dependent reactions in vivo.

178 tive analysis of distinct, highly intermixed cell populations in intact Ce3D-treated tissues via 3D h

179 nd healing and the maintenance of intestinal cell populations in particular compartments.

180 We propose that residual T cell populations in resolved psoriatic lesions represent

181 ve altered hematopoietic stem and progenitor cell populations in the BM and spleen that are hypersens

182 mnar stem cells, one of the most active stem cell populations in the body.

183 DNA methylation patterns in specific immune cell populations in the Fulani to elucidate the mechanis

184 are present in both overlapping and distinct cell populations in the hippocampus, neocortex, and cere

185 uggesting that enteroviruses infect specific cell populations in the human intestine.

186 Here, we characterize the major NK cell populations in the human lung.

187 memory T cell populations, in particular TRM cell populations in the skin.

188 with the CD4(+)CD25(+)Foxp3(+) regulatory T cell populations in the tumor.

189 immune infiltration, to characterize immune cell populations in the urine of patients with NMIBC as

190 te that heterogeneity among responding CD8 T cell populations in their ability to respond to TCR-medi

191 non-invasive long-term tracking of selected cell populations in vivo.Non-invasive cell tracking is a

192 EM2 affects the function of the brain immune cell populations in which it is expressed throughout dis

193 here formation and ALDH-positive cancer stem cell population, in vitro.

194 4 protocols experimentally for batch-matched cell populations, in addition to investigating the effec

195 quired for the optimal formation of memory T cell populations, in particular TRM cell populations in

196 In contrast, epidermal immune cell populations including endogenous T cells, Langerhan

197 f traditional therapeutic agents paired with cell populations including hematopoietic stem cells, reg

198 dentify 50 transcriptionally distinct Arc-ME cell populations, including a rare tanycyte population a

199 N-beta-mediated apoptosis of major leukocyte cell populations, including CD4(+) and CD8(+) T cells.

200 ocesses requires crosstalk between different cell populations, including immune cells and mesenchymal

201 ve gliosis and elevated blood-derived immune cell populations, including phagocytic macrophages and m

202 on of a variety of neuronal and non-neuronal cell populations, including those involved in propriocep

203 fector, memory-precursor and memory CD8(+) T cell populations induced during the in vivo response to

204 lized with amino groups (GONH2) on 15 immune cell populations, interrogating 30 markers at the single

205 uce cancer risk by partitioning the dividing cell populations into lineages comprising infrequently-d

206 g blood-derived and local brain inflammatory cell populations involved in beta-amyloid clearance.SIGN

207 iscarriage, indicating that the memory CD8-T cell population is altered in RM patients.

208 erminal center (GC) development, and the B1a cell population is increased in mice with reduced GC for

209 s, in vitro cell expansion of tooth-inducing cell populations is an essential requirement for further

210 that expression heterogeneity within single-cell populations is regulated.

211 n single cells, particularly within the same cell population, is currently limited by the low sensiti

212 it possible to measure the proteome of mixed cell populations, it has not been possible to isolate ce

213 t prominent within the adaptive CD56(dim) NK-cell population lacking PLZF expression.

214 ealing process, with limited recovery of the cell population later in the healing process.

215 The memory CD8(+) T cell population maintained in the peripheral mucosal tis

216 t the existence of a long-lived, adaptive NK-cell population maintained independently from GPI(pos)CD

217 at the epigenetic landscape within a founder-cell population may contribute to tumor formation.

218 ever, currently it is unknown which of these cell populations mediate GR actions that eventually regu

219 Although specific cell populations mediated the effects of age and sex on

220 ed models show that carrying capacities of T cell populations naturally emerge from the balance betwe

221 eceived renewed interest as an innate-like B cell population of fetal-derived hematopoiesis, responsi

222 everal seconds and subsequently sort a mixed-cell population of varying ratios with high accuracy.

223 ted from undifferentiated and differentiated cell populations of normal, spontaneously immortalized k

224 knockin lines that Fgfr1 is expressed in all cell populations of the blastocyst, while Fgfr2 expressi

225 ignificantly higher in neurons than in other cell populations of the brain.

226 Resident cell populations of the developing brain have been sugge

227 feasibility studies in a lab setting and the cell populations often have reduced proliferation and di

228 increasing fraction of the residual infected cell population on ART, and insertion of HIV proviruses

229 platform for the screening and separation of cell populations on the basis of the in vivo response of

230 Mouse liver contains two natural killer (NK) cell populations, one of which recirculates while the ot

231 thalamic projections to two cortical layer-4 cell populations: one excitatory (putatively regular-spi

232 geneous and simple systems, such as isolated cell populations or early-development models.

233 acterizing mutations in heterogeneous cancer cell populations or identifying cells containing a speci

234 apable of monitoring ions and metabolites in cell populations or whole animals.

235 ion in population dynamics among tissues and cell populations over the course of infection.

236 errogate the biology of highly heterogeneous cell populations, owing to the ability to collect highly

237 properties of CD105-enriched PDL progenitor cell populations (PDL-CD105(+)).

238 However, two NG2-expressing cell populations, pericytes and glia, may also influence

239 of blast colony differentiation, within the cell population positive for the early hematopoietic pro

240 A clear understanding of the immune cell populations regulated by TIGIT and CD96 is key to t

241 ism between distinct myocardial-derived stem cell populations remain obscure.

242 patible tissue is likely due to many small T cell populations responding weakly to hundreds of MHC-bo

243 This matrix is averaged over a large cell population, revealing diagonal blocks called Topolo

244 In the stem cell population, RNF2, the dominant catalytic subunit of

245 Ongoing debates on optimal cell population(s) for treatment of heart failure prompt

246 the trajectory when a primitive streak-like cell population segregated into the mesodermal and endod

247 w that this squamous-columnar junction basal cell population serves as a source of progenitors for th

248 lead to the deterioration of this important cell population.SIGNIFICANCE STATEMENT Although injured

249 To this end, we set up an analysis of cell population structure at the tipping point after sys

250 eneration and to reveal heterogeneity in the cell population studied.

251 ld, which places special demands on resident cell populations such as macrophages.

252 tion and impaired function of several immune cell populations, such as natural killer cells and virus

253 ll TCR locus reconstruction identified three cell populations, T cells, a novel type of NK-like cells

254 also led to the emergence of an immature NK cell population that expressed high levels of the coinhi

255 ng-lived and indispensable Krt15+ progenitor cell population that provides additional perspective on

256 r, CD151 also marked a substantial CD28(+) T cell population that was not marked by CD57.

257 ate infection may target SIV toward distinct cell populations that are able to support high-level vir

258 es reveal a spectrum of tumor-infiltrating T cell populations that are highly similar between tumor m

259 g of hypersensitive sites in a wide range of cell populations that cannot be analyzed using conventio

260 ent signaling, we examined two Shh-dependent cell populations that express high levels of Ptchd1 mRNA

261 generated protective effects against tumour-cell populations that lacked the HER2 receptor.

262 ct relative abundances of circulating immune cell populations that matched traditional hematology.

263 es in the social behavior network, including cell populations that produce isotocin.

264 tratumor heterogeneity and disease-resistant cell populations, that may ultimately unveil novel thera

265 depends on life-long persistence of two stem cell populations: the horizontal basal cells (HBCs), whi

266 the excitability of a unique, IT prefrontal cell population, thereby defining novel circuitry and ce

267 This phenomenon yields a heterogeneous cell population, thereby increasing the potential of dif

268 ng approach to evaluate the contributions of cell populations to bioengineered tooth formation.

269 ovir paradigm to ablate both dividing NG2(+) cell populations to determine whether either scar was al

270 clones and assorted stromal and infiltrating cell populations to pooled genomic data.

271 tinguishes CoB-sensitive and CoB-resistant T cell populations to reduce the risk of CoBRR.

272 ll, and terminally differentiated effector T cell populations to the CD3 and CD28-activated CAR-modif

273 nselective approaches targeting the entire T cell population, TRBC-targeted immunotherapy could eradi

274 receptor and ion channel expression in this cell population vary widely.

275 ges, thereby enhancing expansion of the Treg cell population via IL-10.

276 S AND Isolation of 3 endogenous cardiac stem cell populations was performed from human heart samples

277 of drug resistance in a heterogeneous cancer cell population, we found that autophagy inhibition in d

278 technique for removing behaviorally relevant cell populations, we present evidence that the ovarian s

279 selectively deplete individual innate immune cell populations, we targeted key pathways in Ly6C(low)

280 , or 1 Gy of X-rays, and the growth rates of cell populations were assessed by measuring areas of the

281 Second, infiltrating immune cell populations were decreased in vDeltaK1L-infected ea

282 Morphologic changes in specific cell populations were evaluated by multi-photon confocal

283 Distinct cell populations were produced by performing a doxorubic

284 d in the gut endoderm tissue, a non-neuronal cell population, where it mediates adhesion to fibronect

285 and regulatory CTLA-4(+)IL-2(low)Foxp3(-) T cell population, where the tolerance state is IL-10 depe

286 hylmercury was shown to decrease neural stem cell populations, whereas aerobic fitness has beneficial

287 cavenger receptor expressed on innate immune cell populations which can be shed from the plasma membr

288 cell (Th2 cell), Th17 cell, and regulatory T cell populations while suppressing Th1 cell polarization

289 th low AR expression by targeting a CSC-like cell population with anchorage independence and invasive

290 macrine cells form a neuropeptide-expressing cell population with multiple cell types, which are like

291 contrast, the cytokeratin 8-positive mammary cell population with progenitor properties is elevated i

292 A cell population with progenitor-like phenotype (CD45-CD3

293 We found that mice have many small T cell populations with Ag receptors specific for a foreig

294 for fast phenotyping of functionally diverse cell populations with reasonable accuracy and without th

295 on transcriptional heterogeneity within the cell population, with let-7c increasing and miR-294 decr

296 Input cytokines hierarchically influence the cell population, with TGFbeta being most dominant follow

297 wing for real-time, longitudinal analysis of cell populations within engineered tumor models.

298 ymph nodes and a corresponding increase in T cell populations within the FRT.

299 distinct transcriptomic profiles of multiple cell populations without substantially altering cell phe

300 Kit) expression that enriches for 2 c-Kit(+) cell populations yielding a mixture of cardiac progenito