ライフサイエンスコーパス: cell proliferative response

1 g a significant HER-2/neu protein-specific T-cell proliferative response.

2 , that generated a low-level but clear-cut T cell proliferative response.

3 s nor everolimus could inhibit the CD4CD28 T-cell proliferative response.

4 expression was associated with an impaired T cell proliferative response.

5 cells, and elicits a robust TLR9-dependent B cell proliferative response.

6 also abolishes primary mitogen-induced liver cell proliferative response.

7 amma, TNF-alpha, and IL-6 in the augmented T cell-proliferative response.

8 ory mediators, and failed to induce robust T cell proliferative responses.

9 by significant adaptive CD4(+) and CD8(+) T cell proliferative responses.

10 ergic subjects but did not change in vitro T-cell proliferative responses.

11 e potency of APCs and boost mitogen-driven T-cell proliferative responses.

12 mia was not associated with an increase in T cell proliferative responses.

13 ted in a significant enhancement of T-helper cell proliferative responses.

14 t spleen APC in vitro leads to normal CD4+ T cell proliferative responses.

15 involved in the ability of FDC to inhibit T-cell proliferative responses.

16 er, mIEC did not inhibit splenic alphabeta T cell proliferative responses.

17 nt reduction in both MBP- and PLP-specific T cell proliferative responses.

18 or antibody binding and induction of human T-cell proliferative responses.

19 ncreasing cholesterol efflux suppressed stem cell proliferative responses.

20 ccompanied by diminished antigen-specific, T-cell proliferative responses.

21 mparable levels of IL-2 and IL-4 and similar cell proliferative responses.

22 al blood lymphocytes and better priming of T-cell proliferative responses.

23 nges paralleled reduced IL-2 secretion and T cell proliferative responses after TCR-CD28 stimulation

24 onstruct produced antibodies and exhibited T-cell proliferative responses against core or envelope.

25 The frequency of T-cell proliferative responses against VP2 was significant

26 ignificantly increased autoantigen-induced T cell proliferative responses along with greater numbers

27 on of innate immune responses and adaptive T cell proliferative responses, along with only transient

28 ides containing these sequences stimulated T cell proliferative responses, although less intensely th

29 ld increase in the median p24-induced CD4+ T-cell proliferative response and a 57% increase in the nu

30 of E4 and E1 had little impact on the CD4 T-cell proliferative response and cytolytic activity of CD

31 creased its effectiveness in costimulating T cell proliferative response and early IL-2 production in

32 The in vitro splenic T cell proliferative response and induction of IFN-gamma t

33 characterized by antigen-specific impaired T cell proliferative responses and a distinct pattern of c

34 e treated with recombinant Map had reduced T cell proliferative responses and a significantly reduced

35 mpared with Ab positivity, we assessed the T-cell proliferative responses and Ab responses (islet cel

36 raft histopathology as well as anti-HLA-A2 T-cell proliferative responses and anti-HLA-A2 antibody de

37 Primary T cell proliferative responses and cytokine production (in

38 g that anti-TNF treatment in vivo enhances T cell proliferative responses and cytokine production pro

39 B-cell proliferative responses and differentiation to immu

40 Allogeneic C3H/HeJ (C3H; H2k) T-cell proliferative responses and generation of cytotoxic

41 T-cell proliferative responses and immunoglobulin G antibo

42 ration of T-regulatory cells that suppress T-cell proliferative responses and induce tolerance.

43 insight into how TNF may inhibit endothelial cell proliferative responses and modulate angiogenesis i

44 significant levels of OVA-specific CD4(+) T cell proliferative responses and OVA-induced IFN-gamma a

45 n, significant levels of OVA-specific CD4+ T cell proliferative responses and OVA-induced IL-4 and IL

46 In the mucosa, both Peyer's patch T cell proliferative responses and OVA-specific fecal IgA

47 In contrast, Th cell proliferative responses and secretion of cytokines

48 lsed DC can induce both E7-specific CD4(+) T-cell proliferative responses and strong CD8(+) CTL respo

49 Ex vivo grass antigen-driven T-cell proliferative responses and the frequency of IL-4(+

50 Although we found both a high CD4(+) T cell-proliferative response and TH2 cytokines production

51 and/or SRL both in vitro (by inhibiting of T-cell proliferative response) and in vivo (by inhibiting

52 pecific intrahepatic and peripheral CD4(+) T cell proliferative responses, and cytokines (enzyme-link

53 globulin A (IgA)- and IgG-secreting cells, T-cell proliferative responses, and gamma interferon secre

54 n of maturation markers, IL-12 production, T cell proliferative responses, and IFN-gamma production.

55 They elicited only weak allogeneic T-cell proliferative responses, and repeated stimulation i

56 enhancement in anti-CD3-stimulated CD4(+) T-cell proliferative responses, and this proliferation was

57 The results suggest that HHV-8 T cell proliferative responses are common in HIV-negative

58 llergen-driven IL-4(+) CD4(+) T cells, and T-cell proliferative responses are detectable in the perip

59 present on the surface of donor DCs, donor T cell proliferative responses are generated only in respo

60 T-cell proliferative responses are inhibited during the er

61 HIV-1-specific CD4+ T cell proliferative responses are not measurable in most

62 mg/kg APAP, these changes plus a potentiated cell-proliferative response are necessary for protection

63 , protective GSH is more abundant, and where cell-proliferative responses are better able to sustain

64 The CD4+ inflammatory T cell proliferative responses as well as CD8+ CTL activit

65 n significantly increased the CEA-specific T-cell proliferative responses as well as the cytolytic T-

66 as negatively associated with HBV-specific T-cell proliferative responses at both time points.

67 y positions induced enhanced specific CD4+ T cell proliferative responses at lower peptide concentrat

68 Despite a compensatory beta-cell proliferative response, beta-cell mass progressivel

69 the regulation of activated CD4(+) T-helper cell proliferative responses; blocking this interaction

70 pe, fail to mount a detectable FV-specific T-cell proliferative response but nevertheless produce FV-

71 eneic MLRs between DCs and T cells reduced T cell proliferative responses but did so less efficiently

72 necrosis factor alpha failed to block the T cell proliferative responses, but anti-IL-2 was strongly

73 timulatory activity for primary and memory T-cell proliferative responses, but this was substantially

74 terized by a lack of virus-specific CD4(+) T-cell-proliferative responses, but strong responses have

75 monocyte (MO) cultures inhibited mitogenic T cell proliferative responses by > 95%.

76 Suppression of CD4(+) T cell proliferative responses by both CD25(+) and CD25(-)

77 e formation prior to the induction of full T cell proliferative responses by concurrent indirect Ag p

78 ory T cells that more efficiently suppress T cell proliferative responses by mixed leukocyte reaction

79 hock-protein peptides elicited significant T-cell proliferative responses by the gamma delta subset o

80 ells, B cells, or natural killer cells, or T-cell proliferative response compared with interferon bet

81 s showed enhanced suppressive activity for T cell proliferative responses compared with freshly isola

82 H/K ATPase-specific T cell proliferative responses could first be detected 5 w

83 d activation of beta-catenin, and epithelial cell proliferative responses during C. rodentium infecti

84 Suppression of T cell-proliferative responses during malaria has been att

85 kground resulted in a dramatically reduced B cell proliferative response following IgM ligation, char

86 284, 295-314, and 305-324) elicited strong T-cell proliferative responses from all strains of mice wh

87 re, both the magnitude of p24-induced CD4+ T-cell proliferative responses from CD8-depleted PBMC and

88 These p24-induced CD4+ T-cell proliferative responses from CD8-depleted PBMC were

89 emonstrated CMV-specific CD4(+) and CD8(+) T cell proliferative responses from PBMC, with CD4(+)IFN-g

90 induced a rapid increase in NK activity, NK cell proliferative responses, generation of lymphokine-a

91 Our results suggest that the inhibition of T cell proliferative response in microgravity culture is a

92 of GFAP filament assembly and inhibition of cell proliferative response in Muller glia.

93 ptophan (1-mT) results in increased CD4(+) T-cell proliferative response in PBMCs from HIV-infected p

94 developmental abnormality in the epithelial cell proliferative response in those mice.

95 eta fusion cells failed to induce a strong T cell proliferative response in vitro, mainly due to the

96 Interestingly, most HCV-specific CD4 T-cell proliferative responses in AA patients were unaccom

97 HIV-1 Ag-specific CD4(+) T cell proliferative responses in human subjects with adva

98 T-cell proliferative responses in individuals older than 1

99 the CTLp frequency, anti-NP Ab titers, and T cell proliferative responses in mice that were injected

100 f-life becomes apparent during analyses of T cell proliferative responses in mice, particularly when

101 The inhibitory activity of GR1 reduced T cell proliferative responses in MLR and induced Ag-speci

102 on of cell cycle progression and sustained T cell proliferative responses in naive T cell populations

103 epitope, peptide 5 (P5), stimulates strong T cell proliferative responses in subjects with delayed (D

104 rtial BAFF neutralization rescues aberrant B cell proliferative responses in such mice.

105 nd TILN immunization induced specific CD4+ T cell proliferative responses in the iliac lymph nodes, w

106 The peptide also induced LT-B-specific T-cell proliferative responses in these mice.

107 rally marked, but temporary suppression of T-cell proliferative responses in vitro to phytohemaggluti

108 low level of immunogenicity; (4) decreased T-cell proliferative responses in vitro, and (5) did not i

109 Like C1q, HCV core can inhibit T-cell proliferative responses in vitro.

110 sing of DC to efficiently trigger specific T-cell proliferative responses in vitro.

111 ce to generate secondary anti-VSV CTL and Th cell proliferative responses in vitro.

112 nization with this construct elicited CD4+ T cell proliferative responses in vivo.

113 Human HSCs did not stimulate allogeneic T-cell proliferative response, indicating that they are no

114 CD4(+) T-cell proliferative responses indicative of breakdown of

115 ally, both internalization of CD26 and the T cell proliferative response induced by CD26-mediated cos

116 CMX-13 inhibited T cell proliferative responses induced by Con A and alloan

117 The peripheral blood T cell proliferative responses induced by topo I and in vi

118 However, B cell-proliferative responses induced by stimulation of t

119 The results suggest that a strong T-cell proliferative response is induced upon rechallenge

120 blished in male mice: ZP3 peptide-specific T cell proliferative response is reduced and AOD is absent

121 dose levels of vaccine, peptide-specific, T-cell proliferative responses (n = 3) and/or DTH response

122 Peripheral blood mononuclear cell proliferative responses of 25 controls and 10 patie

123 T cell proliferative responses of B6.129S1-IL-12rb2(tm1Jm)

124 In contrast with B cells, proliferative responses of CD44(hi) CD8(+) cells

125 ell deficiency did not significantly alter T cell proliferative response or cause a shift in the Th1/

126 nd inguinal lymph nodes, without affecting T cell proliferative responses or levels of anticollagen a

127 The prevention of a myeloma cell proliferative response resulting from inhibition of

128 mmaRIIB only modestly affected initial CD4 T cell proliferative responses, suggesting that FcgammaRII

129 anergy to recall antigens and lower (<70%) T-cell proliferative responses than controls after activat

130 resulted in abrogation of hapten-specific T cell proliferative responses that correlated with dimini

131 d of infected individuals, inhibited human T cell proliferative response through interaction with the

132 dendritic cell responses (flow cytometry), T-cell proliferative responses (thymidine incorporation),

133 peptide tolerance suppressed the in vitro T cell proliferative response to AChR and its dominant alp

134 In addition, the T-cell proliferative response to allogeneic LC-derived mDC

135 f T-cell tolerance was assessed by splenic T-cell proliferative response to antigen at 5 weeks.

136 otective effect is associated with reduced T-cell proliferative response to B-(9-23) in B-(9-23)-trea

137 wild-type C57BL/6 mice and had an enhanced T cell proliferative response to bovine CII.

138 s little as 5 microM PAHA led to a 10-fold T cell proliferative response to chromatin in short term o

139 The T-cell proliferative response to HBcAg did not differ betw

140 ne viral load or CD4+ T cell count and the T cell proliferative response to HIV-1 Gag.

141 iency only partially reduced the naive CD8 T cell proliferative response to IL-15/IL-15Ralpha complex

142 as associated with a significantly reduced T cell proliferative response to mycobacterial Hsp65, whic

143 uction in EAE correlated with a diminished T cell proliferative response to myelin basic protein in t

144 cted with T. gondii developed a gammadelta T cell proliferative response to parasite Ag.

145 RS-1 nor IRS-2 overexpression induced a beta-cell proliferative response to TGF-alpha/EGF.

146 cretion and were unable to induce a normal T cell proliferative response to TT.

147 but two patients made primary antibody and T-cell proliferative responses to a foreign antigen admini

148 lowered serum autoantibody levels, reduced T cell proliferative responses to AChR, and an expansion i

149 immunocompromised, with reduced polyclonal T cell proliferative responses to alloantigen, defined pep

150 17 receptor (R):Fc fusion protein inhibits T-cell proliferative responses to alloantigens and prolong

151 m four different colonies side-by-side for T-cell proliferative responses to an expanded panel of aut

152 ell functions including IL-2 secretion and T cell proliferative responses to CD28 plus T cell recepto

153 Assays were performed to study T cell proliferative responses to CII in peripheral blood

154 T cell proliferative responses to diabetes-associated Ags

155 We compare changes in lymphocyte subsets, T cell proliferative responses to disease-associated targe

156 iltration into grafts but not with altered T-cell proliferative responses to donor stimulators.

157 The induction of CD4+ T cell proliferative responses to eight synthetic peptides

158 iding sufficient help to allow optimal CD8 T cell proliferative responses to exosomal protein.

159 /- --> F1 chimeras were also able to mount T-cell proliferative responses to foreign antigens equal t

160 rst, neither APC type was able to initiate T cell proliferative responses to full-length native Topo

161 The human T cell proliferative responses to GA were HLA class II DR-

162 nd untreated MS patients exhibit prominent T cell proliferative responses to GA.

163 kinase proto-oncogene, reportedly modulates cell proliferative responses to growth factors, contract

164 T-cell proliferative responses to HER-2/neu peptides and i

165 It has been suggested that CD4+ T cell proliferative responses to HIV p24 Ag may be import

166 elper lymphocytes, manifested by increased T cell proliferative responses to HIV-1 Gag and recall ant

167 A range of T-cell proliferative responses to HPV-11 VLP were observed

168 ever, it has been difficult to demonstrate T cell proliferative responses to human insulin in IDDM pa

169 Their peripheral blood mononuclear cell proliferative responses to immunogen stimulation 4

170 in, saliva IgA binding to insulin, or CD4+ T-cell proliferative responses to insulin were observed in

171 nd saliva IgA binding to insulin, and CD4+ T-cell proliferative responses to insulin.

172 of 25 tested persons made antigen-specific T cell proliferative responses to L2E7, and peripheral blo

173 B-cell proliferative responses to lipopolysaccharide were

174 fter the transplantation of thymus tissue, T-cell proliferative responses to mitogens developed in fo

175 All 7 survivors developed T-cell proliferative responses to mitogens of more than 10

176 L-12 significantly increased PBMC and CD4+ T cell proliferative responses to p24 Ag in HIV-infected,

177 T cell proliferative responses to purified HHV-8 were meas

178 T-cell proliferative responses to SIV gp140 and T-helper e

179 granule precursor cells and enhances granule cell proliferative responses to Sonic hedgehog.

180 oavailability facilitated the induction of T cell proliferative responses to suboptimal stimuli.

181 T-cell proliferative responses to synthetic peptides demon

182 acrophages and DCs directly regulate human B-cell proliferative responses to T-cell-independent stimu

183 Primary T cell proliferative responses to TCR ligation plus CD28 c

184 Eleven of the 21 patients also developed T cell proliferative responses to the homologous self-Ag.

185 CD4 T cell proliferative responses to the pneumococcal protein

186 Considerable heterogeneity in the T-cell proliferative responses to these three variant anti

187 s, inhibition of SIV replication, and CD4+ T cell proliferative responses to three of the extracellul

188 T cell proliferative responses to topo I were detected in

189 w also had a reduced capacity to stimulate T cell proliferative responses to tubercle bacillus Ag 85.

190 lidated linear discriminant analysis using T cell proliferative responses to two regions of Tri r 2 (

191 munization, respectively), in increases in T cell-proliferative response to HPV-16 L1 VLPs (P<.001).

192 rosis, but had no inhibitory effect on the T cell-proliferative response to myelin basic protein (MBP

193 T cell-proliferative responses to a single epitope, HEL47-

194 nt than untreated DCs in driving syngeneic T cell-proliferative responses to staphylococcal enterotox

195 detected by inhibition of the Ag-specific T cell proliferative response upon Ag presentation by IFN-

196 lity to enhance anti-CD3-stimulated CD4(+) T cell proliferative responses via B7-1 and B7-2.

197 ability to transduce CLL cells, a vigorous T-cell proliferative response was obtained using cells tra

198 endritic cells (DCs) to induce Ag-specific T cell proliferative responses was significantly reduced c

199 ed subsets of lymphocytes and quantitative T-cell proliferative response were assessed in an explorat

200 ti-IgM- and anti-CD40 plus anti-Ig-induced B cell proliferative responses were decreased in BXD2-Aicd

201 r neutralizing antibodies nor SIV-specific T-cell proliferative responses were detectable in any of t

202 ll as anti-HLA-A2 antibody development and T cell proliferative responses were determined at days +5,

203 delayed-type hypersensitivity and splenic T cell proliferative responses were examined, Peyer's patc

204 V core epitopes; however, the humoral and Th cell proliferative responses were found to be weak.

205 oy islet tissue in vivo though spontaneous T-cell proliferative responses were observed in prediabeti

206 rsistent, and vigorous HIV-1-specific CD4+ T cell proliferative responses were present, resulting in

207 T cell proliferative responses were seen with all encephal

208 Furthermore, specific CD4(+) and CD8(+) T cell proliferative responses were significantly increase

209 In these animals, MOG-specific T cell proliferative responses were transiently suppressed

210 a significant increase in PBLs, but T and B cell-proliferative responses were not consistently enhan

211 ture DCs were used to stimulate allogeneic T cells, proliferative responses were dampened (approximat

212 sole class II molecule generated a robust T cell-proliferative response when primed with peptide 2 o

213 newborn blood specimens tested also showed T cell proliferative responses, which included a marked ex

214 h specific impairment of ex vivo antidonor T cell proliferative responses, which was not reversed by

215 These data suggest that Ply induces CD4 T cell proliferative responses with production of IFN- gam

216 e absence of strong HIV-1-specific, CD4(+) T-cell-proliferative responses, yet the mechanism underlyi