ライフサイエンスコーパス: cell receptor

1 surface of the virus and SLAMF1, the immune cell receptor.

2 ion, which circumvents the need for original cell receptor.

3 d with MOG by MOG-specific B cells via the B-cell receptor.

4 surface of Tregs stimulated through their T cell receptor.

5 y one autosome expresses a functional T or B cell receptor.

6 indicating involvement of an additional host cell receptor.

7 etween a sporozoite putative ligand and host cell receptors.

8 ted with adhesive ligands specific to target cell receptors.

9 lentiviral vector expressing HCV-specific T-cell receptors.

10 cted to rare B cells carrying HDM-specific B cell receptors.

11 ths between a self-peptide and the various T cell receptors.

12 T cell receptors activated the T cell proteome and phospho

13 Because stimulation of the B-cell receptor activates JAK2 in CLL cells and the JAK2 i

14 We demonstrate that TDBs trigger T cell receptor activation by inducing target clustering a

15 Ca(2+) signals reported by Salsa6f during T cell receptor activation in naive T cells, helper Th17 T

16 ated phosphatase activities at the site of T-cell receptor activation, which is important for limitin

17 sgenically expressing the diabetogenic AI4 T-cell receptor adoptively transferred disease to otherwis

18 cinoma and express a limited repertoire of T-cell receptors against tumour-associated antigens.

19 th by the germline encoded elements of the T cell receptor alpha and beta chain and, surprisingly, dr

20 germ line encoded portions of CDR3 of the T cell receptor alpha chain.

21 that directing a CD19-specific CAR to the T-cell receptor alpha constant (TRAC) locus not only resul

22 e delta (PI3Kdelta), a linchpin in the pre-B-cell receptor and interleukin 7 receptor signaling pathw

23 other BTK mutations, and other targets in B-cell receptor and MYD88 signaling.

24 t the T cell:APC interface thereby linking T cell receptor and Notch signaling pathways.

25 MDSCs use NO to nitrate both the T-cell receptor and STAT1, thus inhibiting T-cell activati

26 proximal signaling events from activating NK cell receptors and actin dynamics were necessary to main

27 provide the antigen recognition portion of B-cell receptors and derivative antibodies.

28 recognize peptide/MHC complexes with their T-cell receptors and initiate adaptive immune responses.

29 Natural killer cell receptors and other genes related to the immune sys

30 s show how specific interactions between GBM cell receptors and scaffold components contribute signif

31 ing to CD3, the signaling component of the T-cell receptor, and a tumor target have shown clinical ac

32 ted mRNA expression of inhibitory NKR-P1A NK cell receptor, and blocking of NKR-P1A with specific mAb

33 Platelet glycoprotein Ib, T-cell receptor, and integrins are used as examples to ill

34 ory activity that reduced T-cell receptor, B-cell receptor, and interferon signaling in B cells.

35 hermore, we find that PTIP is required for B cell receptor- and T:B interaction-induced proliferation

36 ka envelope protein (ZENV) and proposed host cell receptors: AXL, HSP70, and TIM-1.

37 ed potent inhibitory activity that reduced T-cell receptor, B-cell receptor, and interferon signaling

38 verse cellular signaling events, including B cell receptor (BCR) activation, are hypothesized to be f

39 nts harbor mutations in the interconnected B-cell receptor (BCR) and CXCR4 signaling pathways.

40 ion of Ahr in B cells is up-regulated upon B-cell receptor (BCR) engagement and IL-4 treatment.

41 a Ubqln1(-/-) mouse strain, we found that B cell receptor (BCR) ligation of Ubqln1(-/-) B cells led

42 Although inhibitors targeting the B-cell receptor (BCR) pathway have been successful in the

43 d with 2 or more mutations, and linked the B cell receptor (BCR) pathway to trisomy 12, an important

44 To investigate the effects of aging on B-cell receptor (BCR) repertoire evolution during an immun

45 delalisib, and dasatinib, drugs that block B cell receptor (BCR) signaling and are used in the treatm

46 e B-ALLs encode proteins implicated in pre-B-cell receptor (BCR) signaling and migration/adhesion, wh

47 cells in sIgM (-/-) mice display increased B cell receptor (BCR) signaling as judged by increased lev

48 However, the role of Rictor on B cell receptor (BCR) signaling as well as the underlying

49 diated genomic modification to investigate B-cell receptor (BCR) signaling in cell lines of diffuse l

50 In this study, we used chronic active B-cell receptor (BCR) signaling in diffuse large B-cell ly

51 Recent studies revealed the importance of B-cell receptor (BCR) signaling in maintaining MCL surviva

52 Targeting B-cell receptor (BCR) signaling is a successful therapeuti

53 Altered B-cell receptor (BCR) signaling might contribute to the de

54 gest a link between MYC overexpression and B-cell receptor (BCR) signaling molecules in B-NHL, signal

55 dothelial cell angiogenesis, regulation of B-cell receptor (BCR) signaling, and the survival, activat

56 ked to chronic infection, which may induce B-cell receptor (BCR) signaling, resulting in aberrant B-c

57 We discuss targeting of B cell receptor (BCR) signaling, with emphasis on identify

58 a (PCNSL) harbors mutations that reinforce B cell receptor (BCR) signaling.

59 lunteers, the balance between the CD40 and B-cell receptor (BCR) signalling modulated IL-10 productio

60 nhibited the activation of Akt kinase upon B-cell receptor (BCR) stimulation.

61 ed to regulate signaling downstream of the B-cell receptor (BCR), Fc receptors (FcRs), and toll-like

62 rgy induced by continual engagement of the B-cell receptor (BCR), such as high expression of phosphor

63 we have described a relationship among the B cell receptor (BCR), TLR9, and cytokine signals that reg

64 Mutations in genes promoting the tonic B-cell receptor (BCR)-->PI3K pathway (TCF3 and ID3) did no

65 B-cell receptor (BCR)-activated B cells contribute to path

66 Cell-autonomous B-cell receptor (BcR)-mediated signalling is a hallmark fe

67 initiated by the binding of antigen to the B-cell receptor (BCR).

68 els of B-lineage transcription factors and B cell receptor (BCR)/pre-BCR-signaling genes.

69 ntibodies (sIg) or as membrane-bound (mIg) B cell receptors (BCRs) through alternative RNA splicing.

70 tes preimmune Ig repertoires, expressed as B cell receptors (BCRs).

71 0% of cells have recombined the DNA of one T cell receptor beta (TCRbeta) V-to-DJ-joined allele in a

72 equencing to compare the global changes in T cell receptor beta chain complementarity determining reg

73 using mice expressing one of two different T cell receptor beta chains and various MHC alleles, we sh

74 CD8+ T-cells subsets were reconstituted in T-cell receptor beta knockout mice by adoptive transfer, a

75 T-cell subsets in T-cell receptor beta knockout mice were reconstituted by a

76 ed on the mutually exclusive expression of T cell receptor beta-chain constant domains 1 and 2 (TRBC1

77 by vector integration site sequencing and T-cell receptor beta-chain rearrangement sequencing, corre

78 Using T-cell receptor-beta sequencing and tumour reactivity assa

79 tive infection with wild-type and epithelial cell receptor-blind viruses demonstrated the importance

80 g recent force-dependent lifetime data for T cell receptors bound to various ligands.

81 tivalent antigens bind to and cross-link the cells' receptor-bound IgE antibodies.

82 These cells express antigen-specific T or B cell receptors, but behave with innate characteristics.

83 NK cell activation by engaging inhibitory NK cell receptors, but it was recently observed that most p

84 ay amplified signaling through activating NK cell receptors by enhancing calcium flux and LFA-1 integ

85 on of B cells carrying somatically mutated B-cell receptors by follicular helper T (TFH) cells in ger

86 gh which chronic engagement of inhibitory NK cell receptors by self MHC-I molecules preserves cellula

87 Binding to the host cell receptors, CD4 and CCR5, triggers changes in the co

88 CD19, a signaling component of the B cell receptor complex, is one of multiple regulators dri

89 roximal signaling events downstream of the T-cell receptor complex.

90 ylinositol (3,4,5)-trisphosphate (PIP3) on B cell receptor-containing early endosomes and proper sort

91 monoclonal antibodies (mAb) targeting the T-cell receptor coregulatory molecule GITR exert potent th

92 Targeting of myeloid-dendritic cell receptor DC-SIGN by numerous chronic infectious age

93 activated T cells, and ultimately augments T-cell-receptor-dependent production of interleukin 2 by 3

94 Gabapentin impairs the T-cell receptor-driven calcium response and cytokine produ

95 Cavbeta antisense reduces T-cell receptor-driven calcium responses and cytokine prod

96 a monocytogenes binds to the epithelial host cell receptor E-cadherin, which mediates a physical link

97 eminiscent of mechanical regulation of the T-cell receptor, E-cadherin, and Notch pathways, suggestin

98 The B-cell receptor enables individual B cells to identify div

99 Using this mouse model, we show that T-cell receptor engagement is critical for malignant trans

100 Although T-cell receptor engagement was sufficient to induce CD39 o

101 nities of PD-1 are as high as those of the T cell receptor for agonist pMHC and of LFA-1 (lymphocyte

102 xhibited the capacity to utilize alternative cell receptors for host binding.

103 Although there are currently no known host cell receptors for TcdA, three cell-surface receptors fo

104 B-cell receptors form ordered clusters to recruit kinases

105 ssociated with CMV and EBV infections, and T-cell receptor gammadelta(+) T cells were predominantly a

106 ll subsets (CD4, CD8, WC-1, and gammadelta T cell receptor [gammadelta-TCR]) and cytokines examined (

107 These Mphi precursors have non-rearranged B-cell receptor genes and coexpress myeloid (GR1, CD11b, a

108 mplementarity determining region 3 of each B cell receptor heavy chain in every patient repertoire as

109 gen receptors of jawed vertebrates (B- and T-cell receptors), heterodimers formed by pairs of Ig doma

110 was originally identified as an orphan beta-cell receptor; however, subsequent studies demonstrated

111 ard MRD monitoring based on immunoglobulin/T-cell receptor (Ig/TCR) gene rearrangements and with quan

112 we transferred B cells with germline VRC01 B cell receptors into congenic recipients to elucidate the

113 ffinity of human CD1d-sulfatide for the iNKT cell receptor is relatively low compared with CD1d-alpha

114 hat positive selection-induced MHC bias of T cell receptors is affected both by the germline encoded

115 The activating NK cell receptor KIR2DS1 has been shown to be involved in m

116 ptide-dependent binding of the activating NK cell receptor KIR2DS1, providing new insights into the u

117 uncharacterized ligand for the activating NK cell receptor KIR2DS2.

118 une cells, or blocking interaction with host cell receptors, making them a desirable component of a s

119 igen, the non germline encoded elements of T cell receptors may help the proteins cope with the extre

120 BTK plays a critical role in the B cell receptor mediated inflammatory signaling in the rhe

121 patients with HCV infection in response to T-cell receptor-mediated but not cytokine-mediated stimula

122 on of cytotoxic T lymphocytes depends upon T cell receptor-mediated let-7 downregulation.

123 The MAIT cell response to T-cell receptor-mediated stimulation did not change during

124 s between the virus spike and the mouse host cell receptor, mouse DPP4 (mDPP4).

125 on, and autoimmunity by signaling through NK cell receptors (NKRs).

126 s in self and non-self ligands via paired NK cell receptors (NKRs).

127 Sequence analysis of T-cell receptors of CD8(+) T cells revealed the presence o

128 Some studies have linked apoptotic cell receptors on cardiac macrophages to tissue repair;

129 ic gH/gL complex binds to the EBV epithelial cell receptor or gp42, which binds to the B-cell recepto

130 Activation of the B cell receptor pathway activates lytic viral expression i

131 The pre-T cell receptor (pre-TCR) guides early thymocytes through

132 used to study host gene expression, B-cell/T-cell receptor profiles (BCR/TCR), and potential viral in

133 cterized by expression of a semi-invariant T-cell receptor, rapidly produce copious amounts of divers

134 Mature T cells bearing alphabeta T cell receptors react with foreign antigens bound to alle

135 d, and 1-DER T cells carrying a transgenic T-cell receptor reactive to Der p 1 allergen were used as

136 A NO donor inhibited OT II T cell receptor recognition of OT II specific tetramers, t

137 s/muL, CD45RA < 10%, or a restricted Vbeta T-cell receptor repertoire (<13 of 24 families) were assoc

138 Based on T cell receptor repertoire analysis, we found that PD-1-ex

139 ifferentiation resulting in an oligoclonal T-cell receptor repertoire and enhanced cytokine secretion

140 lso impacts the B-cell compartment and the B-cell receptor repertoire in patients not affected by MC

141 While AD harbors a highly polyclonal T-cell receptor repertoire, and despite the lack of inform

142 f infiltrating immune cell types, the T or B cell receptor repertoire, and direct the design of a per

143 reuteri did not shape the DP-IEL-TCR (TCR, T cell receptor) repertoire but generated indole derivativ

144 ocal microscopy imaging, we studied the host cell receptor(s) responsible for bacterial uptake via in

145 ply the Haystack Heuristic to nine million B-cell receptor sequences obtained from nearly 100 individ

146 ncing (WES), RNA sequencing (RNA-seq), and T cell receptor sequencing (TCR-seq) of pretreatment tumor

147 High-throughput T cell receptor sequencing approaches have opened up new p

148 attachment proteins mediate binding to host cell receptors, serve critical functions in cell and tis

149 e major histocompatibility complex and the T cell receptor (Signal 1) and between CD80 or CD86 and CD

150 emodeling (ARHGEF3), RNA splicing (U2AF1), T-cell receptor signaling (PTPRN2, RLTPR), and T-cell diff

151 l targeted therapies such as inhibitors of B-cell receptor signaling and B-cell lymphoma 2 have opene

152 B cell receptor signaling and downstream NF-kappaB activit

153 In the face of persistent antigen, chronic T cell receptor signaling drives T lymphocytes to a functi

154 Constitutive B-cell receptor signaling leads to overexpression of the a

155 age-gated proton channel-encoding gene and B-cell receptor signaling modulator, were associated with

156 e the expression of many components of the B cell receptor signaling pathway and the receptors for CD

157 ently described scaffolding protein in the T-cell receptor signaling pathway.

158 We conclude T cell receptor signaling via Itk controls the development

159 hways regulating estrogen, glucocorticoid, B-cell receptor signaling, and ATM signaling.

160 's tyrosine kinase (BTK), is essential for B-cell receptor signaling, and most resistant cases carry

161 critical in Treg, acting there to control T-cell receptor signaling, cell proliferation, and surviva

162 rotein, which mimics constitutively active B cell receptor signaling, is required for EBV-induced lym

163 hether the EBV protein LMP2A, which mimics B cell receptor signaling, is required for EBV-induced lym

164 K SH2 domains in kinase autoinhibition and T-cell receptor signaling, monobodies binding the Src and

165 diating energy metabolism, cell cycle, and B cell receptor signaling.

166 the survival of B cells by mimicking host B-cell receptor signaling.

167 lation of genes involved in pathways, like B cell receptor signaling.

168 miR-28 targets involved in cell-cycle and B-cell receptor signaling.

169 ly deleted and include LYN, a regulator of B-cell receptor signaling.

170 Combinatorial disruption of B-cell receptor signalling and PI3K-AKT-mTOR axis leads to

171 il is an E3 ubiquitin ligase that inhibits T-cell receptor signalling in CD4(+) T cells.

172 icroscopy and T cells transfected with the T-cell receptor specific for the birch pollen allergen Bet

173 SV-1 gD (i) neutralized HSV-1 infection in a cell receptor-specific manner, (ii) mediated ADCC, and (

174 were taken up by B cells independently of B-cell receptor specificity, indicating that HDM uptake an

175 We revealed that altering T-cell receptor stimulation influenced recruitment of mRNA

176 oRNA content in EVs released upon in vitro T cell receptor stimulation of Th1, Th17, and T regulatory

177 cally inhibits B cell responses induced by B cell receptor stimulation with antigen.

178 Upon T cell receptor stimulation, CD4(+) T helper (Th) lymphocy

179 mma2 and its downstream pathways following B cell receptor stimulation.

180 h refers to a state of unresponsiveness to B cell receptor stimulation.

181 enough to discriminate pMHC half-lives and T cell receptor (TCR) accumulation selectively stabilized

182 imit T-cell efficacy, including suboptimal T-cell receptor (TCR) activation and an immunosuppressive

183 During early T-cell receptor (TCR) activation, phosphorylation of linke

184 T-cell receptor (TCR) allorecognition is often presumed to

185 e H3.3K27M mutation, complementary DNA for T cell receptor (TCR) alpha- and beta-chains were cloned i

186 human IgA CH3, IgD CH3, IgG1 CH3, IgM CH4, T-cell receptor (TCR) alpha/beta, and TCR gamma/delta cons

187 or mMUD HSCT after depleting GvHD-causing T-cell receptor (TCR) alphabeta CD3(+) cells from the graf

188 ordance with the requirement that both the T cell receptor (TCR) and CAR be engaged to accelerate T c

189 ing high-throughput screening (HTS) of the T cell receptor (TCR) and immunostaining, we found that cl

190 Although the T-cell receptor (TCR) and LFA-1 can generate intracellular

191 of this cell-cell interface, within which T cell receptor (TCR) and peptide major histocompatibility

192 of genes associated with Notch receptors, T cell receptor (TCR) assembly, and TCR-mediated signaling

193 histocompatibility class II molecules and T-cell receptor (TCR) beta-chain variable domains (Vbetas)

194 whether intratumoral and peripheral blood T cell receptor (TCR) clonality inform clinical outcomes i

195 To define the role of individual T-cell receptor (TCR) clonotypes in differential antiviral

196 ells are activated through ligation of the T cell receptor (TCR) complex, leading to the induction of

197 e by measuring the binding strength of its T cell receptor (TCR) for peptide-loaded MHCs (pMHC) on an

198 MHC class II (MHC-II) gene, HLA-DR2a, and T-cell receptor (TCR) genes specific for MBP87-99/DR2a tha

199 ally modified to express a cancer-specific T-cell receptor (TCR) has shown significant therapeutic po

200 evelop from DP cells after partial-agonist T cell receptor (TCR) interactions with self-peptide/MHC,

201 Signaling through the T-cell receptor (TCR) is critical for T-cell development a

202 , created by transduction of a recombinant T-cell receptor (TCR) isolated from a hemophilia A subject

203 e discovered a non-MHC-linked Ir gene in a T cell receptor (TCR) locus that was required for CD8(+) T

204 hepatitis B virus-specific (HBV-specific) T cell receptor (TCR) may supplement HBV-specific immune r

205 A-A*02:01 molecules for recognition by the T cell receptor (TCR) of cytotoxic T cells.

206 pMHC) on an antigen-presenting cell to the T cell receptor (TCR) on a T cell.

207 m high affinity agonist recognition by the T cell receptor (TCR) or from a death receptor, such as tu

208 ate-like T cells expressing the gammadelta T cell receptor (TCR) rather than the alphabeta TCR could

209 s comprise a first line of defense through T-cell receptor (TCR) recognition of stressed cells.

210 the Chimeric Antigen Receptors (CARs) and T-cell Receptor (TCR) redirection.

211 overning mycolate antigenicity for the GEM T cell receptor (TCR) remain poorly understood.

212 compartment must contain diversity in both T cell receptor (TCR) repertoire and cell state to provide

213 hibited mature naive phenotypes, a diverse T cell receptor (TCR) repertoire and TCR-dependent functio

214 Defects in T cell receptor (TCR) repertoire are proposed to predispos

215 licting literature on the diversity of the T-cell receptor (TCR) repertoire in lesional AD, and its r

216 The regulatory T cell (T reg cell) T cell receptor (TCR) repertoire is highly diverse and ske

217 The prevalent Vdelta1 T cell receptor (TCR) repertoire is private and initially

218 MHC specificity of the T cell receptor (TCR) repertoire is shaped during thymic d

219 nology, but these animals contain a biased T cell receptor (TCR) repertoire that might affect immune

220 T-cell receptor (TCR) repertoires directed to some immunod

221 W131A mutant mice with wild-type T cell receptor (TCR) repertoires exhibited relatively nor

222 Diversity of T cell receptor (TCR) repertoires, generated by somatic DN

223 By analyzing T-cell receptor (TCR) sequence repertoires taken from the

224 T cell receptor (TCR) sequences are very diverse, with man

225 e individual cells, coupled with assembled T cell receptor (TCR) sequences, enable us to identify 11

226 on with high-risk HLA genes using a direct T-cell receptor (TCR) sequencing approach without long-ter

227 Furthermore, T-cell receptor (TCR) sequencing identified many expanded

228 yzed by whole-exome, transcriptome, and/or T cell receptor (TCR) sequencing.

229 In Th2 cells, T cell receptor (TCR) signaling activates the transcriptio

230 irus (formerly named GBV-C) interfere with T-cell receptor (TCR) signaling by novel RNA and protein-b

231 Strong T cell receptor (TCR) signaling largely induces cell death

232 Mechanistically, T cell receptor (TCR) signaling molecule protein kinase C

233 his is potentially attributed to decreased T cell receptor (TCR) signaling strength due to inefficien

234 ive (DP) thymocytes respond to intrathymic T-cell receptor (TCR) signals by undergoing positive selec

235 Here we examined how T cell receptor (TCR) signals establish and arbitrate Bcl6

236 a fate-determination process mediated via T cell receptor (TCR) signals for differentiation into dis

237 tes the NF-kappaB signal transduction upon T-cell receptor (TCR) stimulation by specifically suppress

238 Even though T-cell receptor (TCR) stimulation together with co-stimula

239 ibility complex (MHC)-restricted alphabeta T cell receptor (TCR) T cells and non-MHC-restricted gamma

240 pecific CD8 T cells in vitro with a second T-cell receptor (TCR) that recognizes a bacterial antigen.

241 Malaria antigen-specific B5 T cell receptor (TCR) transgenic (Tg) T cells from chronic

242 T-cell receptor (TCR) triggering and subsequent T-cell act

243 a broad repertoire of target antigens and T cell receptor (TCR) usage, with initial evidence of publ

244 MAIT cell responses to SEB can occur in a T cell receptor (TCR) Vbeta-specific manner but are largel

245 specific recognition by T cells is via the T cell receptor (TCR) which is unique for each T cell.

246 the interaction of a clonotypic alphabeta T-cell receptor (TCR) with a peptide-loaded major histocom

247 , T cells interact through their alphabeta T cell receptor (TCR) with peptide-major histocompatibilit

248 OT-II mice expressing a transgenic T cell receptor (TCR) with specificity for ovalbumin (OVA)

249 ntiate in response to signals engaging the T cell receptor (TCR), express high levels of the immunosu

250 d by a heterodimeric surface receptor, the T cell receptor (TCR), that mediates recognition of pathog

251 ifferentiation, namely on the role of both T cell receptor (TCR)-dependent and TCR-independent factor

252 (IP3) production, leading to a decrease in T cell receptor (TCR)-dependent intracellular Ca(2+) respo

253 Vgamma9Vdelta2 cells underwent rapid T cell receptor (TCR)-dependent proliferation and function

254 Adoptively transferred T-cell receptor (TCR)-engineered T cells depend on host-de

255 heral tissues, SFB selectively expand dual T cell receptor (TCR)-expressing Th17 cells recognizing bo

256 ereby contributing to host resistance in a T cell receptor (TCR)-independent manner.

257 ever, common Treg expansion approaches use T-Cell Receptor (TCR)-mediated stimulation which also caus

258 studies have identified several subsets of T cell receptor (TCR)-negative IELs with intriguing proper

259 thought to suppress signaling through the T cell receptor (TCR).

260 trikingly, we found that antigen receptor [T-cell receptor (TCR)] signaling regulates this process th

261 unology as T cells activated through their T cell receptors (TCR) by protein antigens orchestrate imm

262 Negative selection purges thymocytes whose T-cell receptors (TCR) exhibit high affinity to self-pepti

263 Characterisation of the T cell receptors (TCR) involved in immune responses is imp

264 Inherent intermediate- to low-affinity T-cell receptors (TCR) that develop during the natural cou

265 n the context of MHC I and can be bound by T-cell receptors (TCR).

266 ll activation by linking antigen receptor (T cell receptor, TCR) signals to downstream pathways.

267 The extent to which T cell receptors (TCRs) are biased towards MHC proteins in

268 T cell receptors (TCRs) are protein complexes formed by si

269 lycolipid antigens recognized by alphabeta T-cell receptors (TCRs) drive the activation of invariant

270 (pHLA) to screen for antigens of "orphan" T cell receptors (TCRs) expressed on TILs from human color

271 d to express chimeric antigen receptors or T-cell receptors (TCRs) has demonstrated clinical efficacy

272 alphabeta T cell receptors (TCRs) interact with peptides bound to th

273 Thus, T-cell receptors (TCRs) isolated from minor H antigen-spec

274 e investigated the clonal diversity of the T cell receptors (TCRs) of infiltrating IFN-gamma and IL-1

275 ty-maturation campaigns for antibodies and T-cell receptors (TCRs) operate on the residues at the bin

276 atibility complex (MHC) class I-restricted T-cell receptors (TCRs) or chimeric antigen receptors to g

277 Here, anti-HCV T cell receptors (TCRs) recognizing the HCV nonstructural

278 Transfer of T-cell receptors (TCRs) specific for tumor-associated anti

279 Previous studies have demonstrated that T-cell receptors (TCRs) that focus on a minimal motif with

280 A2 produce cytotoxic T lymphocytes bearing T-cell receptors (TCRs) that recognize the immunodominant

281 ymphocytes use surface [Formula: see text] T-cell receptors (TCRs) to recognize peptides bound to MHC

282 During thymic selection, T cells bearing T cell receptors (TCRs) with high affinity for self-antige

283 es can be identified by documenting public T cell receptors (TCRs), we profiled the T cell repertoire

284 targeted by multiple clones with distinct T cell receptors (TCRs).

285 We bred miR-146a-deficient mice with 2D2 T cell receptor-Tg mice to generate 2D2 CD4 T cells that a

286 he NK-cell checkpoint CD96, an inhibitory NK-cell receptor that binds CD155, which was abundantly exp

287 such as chimeric antigen and high-affinity T-cell receptors to deepen the adaptive immune response; a

288 -1 envelope (Env) glycoprotein binds to host cell receptors to mediate membrane fusion.

289 tic cytokines, and (via the semi-invariant T-cell receptor) to bacteria translocated from the gut.

290 ities of B cells were studied by using new T-cell receptor transgenic 1-DER mice specific for the Der

291 Here, we used an autoimmune-prone T-cell receptor transgenic mouse (2D2) and a mouse-adapted

292 n presentation from DCs to CD4(+) T cells (T cell receptor transgenic OT-II) was measured via a [(3)H

293 The B-cell receptor transmembrane activator and calcium modula

294 cell receptor or gp42, which binds to the B-cell receptor, triggering gB-mediated fusion of the viri

295 P36 as a major parasite determinant of host cell receptor usage.

296 We sequenced T-cell receptor Vbeta genes in expanded microbe-reactive T

297 s and intestinal tissue, and had a diverse T-cell receptor Vbeta repertoire.

298 duced high levels of IL-10 and had diverse T cell receptor Vbeta repertoires with an oligoclonal expa

299 s with an oligoclonal expansion in CDR3 of T cell receptor Vbeta14.

300 Moreover, specific T cell receptor-Vbeta5.(1/2) and TCR-Vbeta11 clonal deleti